Projects per year
Personal profile
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
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Projects
- 1 Active
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The impact of obesity on anti-tumour immunity in triple negative breast cancer
Tiganis, T., Goh, P., Rematta, M., Warnecke, E., McLean, C., Darcy, P. & Baell, J.
1/01/22 → 31/12/25
Project: Research
Research output
- 4 Article
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PTP1B Is an Intracellular Checkpoint that Limits T-cell and CAR T-cell Antitumor Immunity
Wiede, F., Lu, K-H., Du, X., Zeissig, M. N., Xu, R., Goh, P. K., Xirouchaki, C. E., Hogarth, S. J., Greatorex, S., Sek, K., Daly, R. J., Beavis, P. A., Darcy, P. K., Tonks, N. K. & Tiganis, T., 1 Mar 2022, In: Cancer Discovery. 12, 3, p. 752-773 22 p.Research output: Contribution to journal › Article › Research › peer-review
Open Access22 Citations (Scopus) -
PTPN2 phosphatase deletion in T cells promotes anti-tumour immunity and CAR T-cell efficacy in solid tumours
Wiede, F., Lu, K-H., Du, X., Liang, S., Hochheiser, K., Dodd, G. T., Goh, P. K., Kearney, C., Meyran, D., Beavis, P. A., Henderson, M. A., Park, S. L., Waithman, J., Zhang, S., Zhang, Z. Y., Oliaro, J., Gebhardt, T., Darcy, P. K. & Tiganis, T., 15 Jan 2020, In: The EMBO Journal. 39, 2, 26 p., e103637.Research output: Contribution to journal › Article › Research › peer-review
Open AccessFile50 Citations (Scopus) -
T-cell–specific PTPN2 deficiency in NOD mice accelerates the development of type 1 diabetes and autoimmune comorbidities
Wiede, F., Brodnicki, T. C., Goh, P. K., Leong, Y. A., Jones, G. W., Yu, D., Baxter, A. G., Jones, S. A., Kay, T. W. H. & Tiganis, T., 1 Jun 2019, In: Diabetes. 68, 6, p. 1251-1266 16 p.Research output: Contribution to journal › Article › Research › peer-review
19 Citations (Scopus) -
Obesity Drives STAT-1-Dependent NASH and STAT-3-Dependent HCC
Grohmann, M., Wiede, F., Dodd, G. T., Gurzov, E. N., Ooi, G. J., Butt, T., Rasmiena, A. A., Kaur, S., Gulati, T., Goh, P. K., Treloar, A. E., Archer, S., Brown, W. A., Muller, M., Watt, M. J., Ohara, O., McLean, C. A. & Tiganis, T., 15 Nov 2018, In: Cell. 175, 5, p. 1289-1306 18 p.Research output: Contribution to journal › Article › Research › peer-review
Open AccessFile189 Citations (Scopus)