1997 …2023

Research activity per year

Personal profile

Biography

Prof. Paul Stupple is a seasoned medicinal chemist with more than 20 years of experience in the global pharmaceutical industry and academia.

He has an outstanding track record of advancing projects to clinical development through progression of effective design strategies, development of exceptional teams and an enthusiastic approach to building strong multidisciplinary relationships.

Prof. Stupple has a BA and DPhil in Chemistry from the University of Oxford in the UK and spent the first decade of his career at Pfizer, UK where, as medicinal chemistry design leader with management responsibility, he provided leadership to multidisciplinary teams which delivered 6 clinical candidates of which 2 have advanced to Phase I clinical trials and 3 to Phase II.

Following a subsequent move to Australia, initially to WEHI and for the past 7 years at Monash University, Prof. Stupple led the Medicinal Chemistry program at the Cancer Therapeutics CRC (CTx), an organisation that ultimately became Canthera Discovery. In this role he led a chemistry program that resulted in two of the largest preclinical licencing agreements ever made in Australia. These included two projects; the first of which was licensed to Merck, Sharp and Dohme (MSD) in 2016, and the second was licensed to Pfizer in 2018 from which its lead compound was nominated as a development candidate and is currently undergoing Phase I clinical trials.

Research interests

Small molecule drug discovery

Expertise related to UN Sustainable Development Goals

In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):

  • SDG 3 - Good Health and Well-being

Education/Academic qualification

Organic Chemistry, DPhil, University of Oxford

1 Oct 199620 Dec 1999

Award Date: 31 Jan 2000

Chemistry, BA, University of Oxford

1 Oct 199231 Jul 1996

Award Date: 31 Aug 1996

External positions

Director, Medicinal Chemistry, Canthera Discovery Ltd

1 Jan 2021 → …

Director, Medicinal Chemistry, Canthera Discovery Ltd

24 Jan 201231 Dec 2020

Collaborations and top research areas from the last five years

Recent external collaboration on country/territory level. Dive into details by clicking on the dots or