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Research Output 2001 2018

46 Citations (Scopus)

A common mechanism of clinical HIV-1 resistance to the CCR5 antagonist maraviroc despite divergent resistance levels and lack of common gp120 resistance mutations

Roche, M. J., Salimi, H., Duncan, R. C., Wilkinson, B., Chikere, K., Moore, M. S., Webb, N., Zappi, H., Sterjovski, J., Flynn, J. K., Ellett, A., Gray, L. R., Lee, B., Jubb, B., Westby, M., Ramsland, P. A., Lewin, S. R., Payne, R. J., Churchill, M. & Gorry, P. R., 2013, In : Retrovirology. 10, 1 (Art. No.: 43), p. 1 - 20 20 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access

A common site of the Fc receptor gamma subunit interacts with the unrelated immunoreceptors FcαRI and FcεRI

Wines, B. D., Trist, H., Ramsland, P. A. & Hogarth, P. M., 2006, In : Journal of Biological Chemistry. 281, 25, p. 17108-17113 7 p.

Research output: Contribution to journalArticleResearchpeer-review

12 Citations (Scopus)

A computational approach for exploring carbohydrate recognition by lectins in innate immunity

Agostino, M., Yuriev, E. & Ramsland, P. A., 2011, In : Frontiers in Immunology. 2, JUN, 14 p., 23.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
21 Citations (Scopus)

Acquisition of functional antibodies that block the binding of erythrocyte-binding antigen 175 and protection against plasmodium falciparum malaria in children

Irani, V. R., Ramsland, P. A., Guy, A. J., Siba, P. M., Mueller, I., Richards, J. S. & Beeson, J. G., 2015, In : Clinical Infectious Diseases. 61, 8, p. 1244 - 1252 9 p.

Research output: Contribution to journalArticleResearchpeer-review

26 Citations (Scopus)

A double mutation of MBP83-99 peptide induces IL-4 responses and antagonizes IFN-gamma responses

Katsara, M., Yuriev, E., Ramsland, P. A., Deraos, G., Tselios, T., Matsoukas, J. & Apostolopoulos, V., 2008, In : Journal of Neuroimmunology. 200, 1-2, p. 77 - 89 13 p.

Research output: Contribution to journalArticleResearchpeer-review

76 Citations (Scopus)

A glycopeptide in complex with MHC class 1 uses the GaINAc residue as an anchor

Apostolopoulos, V., Yuriev, E., Ramsland, P. A., Halton, J., Osinski, C., Li, W., Plebanski, M., Paulsen, H. & McKenzie, I. F. C., 2003, In : Proceedings of the National Academy of Sciences. 100, 25, p. 15029 - 15034 6 p.

Research output: Contribution to journalArticleResearchpeer-review

7 Citations (Scopus)

Allosteric modulation of the HIV-1 gp120-gp41 association site by adjacent gp120 variable region 1 (V1) N-glycans linked to neutralization sensitivity

Drummer, H. E., Hill, M. K., Maerz, A. L., Wood, S. J., Ramsland, P. A., Mak, J. & Poumbourios, P., 2013, In : PLoS ONE. 9, 4, 18 p., e1003218.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
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27 Citations (Scopus)

Altered peptide ligands of myelin basic protein (MBP87-99) conjugated to reduced mannan modulate immune responses in mice

Katsara, M., Yuriev, E., Ramsland, P. A., Tselios, T., Deraos, G., Lourbopoulos, A., Grigoriadis, N., Matsoukas, J. & Apostolopoulos, V., 2009, In : Immunology. 128, 4, p. 521 - 533 13 p.

Research output: Contribution to journalArticleResearchpeer-review

21 Citations (Scopus)

Alternative coreceptor requirements for efficient CCR5- and CXCR4-mediated HIV-1 entry into macrophages

Cashin, K., Roche, M., Sterjovski, J., Ellett, A., Gray, L. R., Cunningham, A., Ramsland, P., Churchill, M. & Gorry, P., 2011, In : Journal of Virology. 85, 20, p. 10699 - 10709 11 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
45 Citations (Scopus)

An altered and more efficient mechanism of CCR5 engagement contributes to macrophage tropism of CCR5-using HIV-1 envelopes

Sterjovski, J., Roche, M. J., Churchill, M., Ellett, A., Farrugia, W., Gray, L. R., Cowley, D., Poumbourios, P., Lee, B., Wesselingh, S. L., Cunningham, A. L., Ramsland, P. A. & Gorry, P. R., 2010, In : Virology. 404, 2, p. 269 - 278 10 p.

Research output: Contribution to journalArticleResearchpeer-review

2 Citations (Scopus)

Antibody-carbohydrate recognition from docked ensembles using the AutoMap procedure

Dingjan, T., Agostino, M. J., Ramsland, P. A. & Yuriev, E., 2015, Carbohydrate-Based Vaccines: Methods and Protocols. Lepenies, B. (ed.). New York NY USA: Springer, p. 41 - 55 15 p.

Research output: Chapter in Book/Report/Conference proceedingChapter (Book)Other

15 Citations (Scopus)

Antibody-ligand docking: insights into peptide-carbohydrate mimicry

Yuriev, E., Sandrin, M. S. & Ramsland, P. A., 2008, In : Molecular Simulation. 34, 4, p. 461 - 468 8 p.

Research output: Contribution to journalArticleResearchpeer-review

13 Citations (Scopus)

Antibody recognition of aberrant glycosylation on the surface of cancer cells

Soliman, C., Yuriev, E. & Ramsland, P., 1 Jun 2017, In : Current Opinion in Structural Biology. 44, p. 1-8 8 p.

Research output: Contribution to journalReview ArticleResearchpeer-review

15 Citations (Scopus)

Antibody recognition of cancer-related gangliosides and their mimics investigated using in silico site mapping

Agostino, M. J., Yuriev, E. & Ramsland, P. A., 2012, In : PLoS ONE. 7, 4, 12 p., e35457.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
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77 Citations (Scopus)

Antimicrobial and immune modulatory effects of lactic acid and short chain fatty acids produced by vaginal microbiota associated with eubiosis and bacterial vaginosis

Aldunate, M. C., Srbinovski, D., Hearps, A. C., Latham, C. F., Ramsland, P. A., Gugasyan, R., Cone, R. A. & Tachedjian, G., 2015, In : Frontiers in Physiology. 6, 23 p., 164.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
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10 Citations (Scopus)

AutoMap: A tool for analyzing protein-ligand recognition using multiple ligand binding modes

Agostino, M. J., Mancera, R., Ramsland, P. A. & Yuriev, E., 2013, In : Journal of Molecular Graphics and Modelling. 40, p. 80 - 90 11 p.

Research output: Contribution to journalArticleResearchpeer-review

12 Citations (Scopus)

Binding of Synthetic Peptides by a Human Monoclonal IgM with an Unusual Combining Site Structure

Edmundson, A. B., Tribbick, G., Plompen, S., Geysen, H. M., Yuriev, E. & Ramsland, P. A., 2001, In : Journal of Molecular Recognition. 14, 4, p. 229 - 238 10 p.

Research output: Contribution to journalArticleResearchpeer-review

16 Citations (Scopus)

Carbohydrate-mimetic peptides: structural aspects of mimicry and therapeutic implications

Agostino, M., Sandrin, M., Thompson, P., Farrugia, W., Ramsland, P. & Yuriev, E., 2011, In : Expert Opinion on Biological Therapy. 11, 2, p. 211 - 224 14 p.

Research output: Contribution to journalArticleResearchpeer-review

38 Citations (Scopus)

Carbohydrate residues downstream of the terminal Galalpha(1,3)Gal epitope modulate the specificity of xenoreactive antibodies

Milland, J., Yuriev, E., Xing, P-X., McKenzie, I., Ramsland, P. A. & Sandrin, M. S., 2007, In : Immunology and Cell Biology. 85, 8, p. 623 - 632 10 p.

Research output: Contribution to journalArticleResearchpeer-review

4 Citations (Scopus)

Carbohydrates in cyberspace

Yuriev, E. & Ramsland, P. A., 2015, In : Frontiers in Immunology. 6, p. 1 - 4 4 p.

Research output: Contribution to journalLetterOther

21 Citations (Scopus)

CD4-binding site alterations in CCR5-using HIV-1 envelopes influencing gp120-CD4 interactions and fusogenicity

Sterjovski, J., Churchill, M. J., Roche, M., Ellett, A., Farrugia, W., Wesselingh, S. L., Cunningham, A. L., Ramsland, P. A. & Gorry, P. R., 20 Feb 2011, In : Virology. 410, 2, p. 418-428 11 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
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172 Citations (Scopus)

Challenges and advances in computational docking: 2009 in review

Yuriev, E., Agostino, M. & Ramsland, P., 2011, In : Journal of Molecular Recognition. 24, 2, p. 149 - 164 16 p.

Research output: Contribution to journalArticleResearchpeer-review

5 Citations (Scopus)

Characterization of a unique conformational epitope on free immunoglobulin kappa light chains that is recognized by an antibody with therapeutic potential

Hutchinson, A. T., Alexova, R., Bockhorni, V., Ramsland, P. A., Jones, D. R., Jennings, C., Broady, K., Edmundson, A. B. & Raison, R. L., 2011, In : Molecular Immunology. 48, 9-10, p. 1245 - 1252 8 p.

Research output: Contribution to journalArticleResearchpeer-review

5 Citations (Scopus)

Cold-induced precipitation of a monoclonal IgM: a negative activation enthalpy reaction

Meliga, S. C., Farrugia, W., Ramsland, P. A. & Falconer, R. J., 2013, In : Journal of Physical Chemistry B. 117, 2, p. 490 - 494 5 p.

Research output: Contribution to journalArticleResearchpeer-review

1 Citation (Scopus)

Computational approaches for studying carbohydrate-lectin interactions in infection

Dingjan, T., Yuriev, E. & Ramsland, P., 22 Feb 2016, Glycobiology and Human Diseases. Wiederschain, G. (ed.). Boca Raton FL USA: CRC Press, p. 129-147 19 p.

Research output: Chapter in Book/Report/Conference proceedingChapter (Book)Researchpeer-review

9 Citations (Scopus)

Conformational alterations in the CD4 binding cavity of HIV-1 gp120 influencing gp120-CD4 interactions and fusogenicity of HIV-1 envelopes derived from brain and other tissues

Gray, L. R., Sterjovski, J., Ramsland, P., Churchill, M. & Gorry, P., 2011, In : Retrovirology. 8, 42, p. 1 - 9 9 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
9 Citations (Scopus)

Covariance of charged amino acids at positions 322 and 440 of HIV-1 Env contributes to coreceptor specificity of subtype B viruses, and can be used to improve the performance of V3 sequence-based coreceptor usage prediction algorithms

Cashin, K., Sterjovski, J., Harvey, K. L., Ramsland, P. A., Churchill, M. J. & Gorry, P. R., 2014, In : PLoS ONE. 9, 10, 11 p., e109771.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
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3 Citations (Scopus)

Cross-species analysis of Fc engineered anti-Lewis-Y human IgG1 variants in human neonatal receptor transgenic mice reveal importance of S254 and Y436 in binding human neonatal Fc receptor

Burvenich, I. J. G., Farrugia, W., Lee, F. T., Catimel, B., Liu, Z., Makris, D., Cao, D., O'Keefe, G. J., Brechbiel, M. W., King, D., Spirkoska, V., Allan, L. C., Ramsland, P. A. & Scott, A. M., 18 May 2016, In : mAbs. 8, 4, p. 775-786 12 p.

Research output: Contribution to journalArticleResearchpeer-review

2 Citations (Scopus)

Crystallization and preliminary X-ray diffraction analysis of monkey dimeric dihydrodiol dehydrogenase

El-Kabbani, O., Chung, R. P-T., Ramsland, P. A., Asada, Y., Ishikura, S., Usami, N. & Hara, A., 2002, In : Acta Crystallographica Section D: Biological Crystallography. D58, Part 1, p. 163 - 164 2 p.

Research output: Contribution to journalArticleResearchpeer-review

20 Citations (Scopus)

Distinct patterns of diversity, population structure and evolution in the AMA1 genes of sympatric Plasmodium falciparum and Plasmodium vivax populations of Papua New Guinea from an area of similarly high transmission

Arnott, A., Wapling, J. A., Mueller, I., Ramsland, P. A., Siba, P. M., Reeder, J. C. & Barry, A. E., 2014, In : Malaria Journal. 13, 1 (Art. No.:233), p. 1 - 16 16 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access

Docking of carbohydrates into protein binding sites

Agostino, M. J., Ramsland, P. A. & Yuriev, E., 2012, Structural Glycobiology. Yuriev, E. & Ramsland, P. (eds.). Boca Raton USA: CRC Press, p. 111 - 140 30 p.

Research output: Chapter in Book/Report/Conference proceedingChapter (Book)Researchpeer-review

20 Citations (Scopus)

Docking of Combinatorial Peptide Libraries into a Broadly Cross-reactive Human IgM

Yuriev, E., Ramsland, P. A. & Edmundson, A. B., 2001, In : Journal of Molecular Recognition. 14, 3, p. 172 - 184 13 p.

Research output: Contribution to journalArticleResearchpeer-review

5 Citations (Scopus)

Engineering anti-Lewis-Y hu3S193 antibodies with improved therapeutic ratio for radioimmunotherapy of epithelial cancers

Burvenich, I. J. G., Lee, F-T., O’Keefe, G. J., Makris, D., Cao, D. X., Gong, S. J., Rigopoulos, A., Allan, L. C., Brechbiel, M. W., Liu, Z., Ramsland, P. A. & Scott, A. M., 1 Dec 2016, In : EJNMMI Research. 6, 1, 13 p., 26.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
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25 Citations (Scopus)

Evidence for structurally conserved recognition of the major carbohydrate xenoantigen by natural antibodies

Ramsland, P. A., Farrugia, W., Yuriev, E., Edmundson, A. B. & Sandrin, M. S., 2003, In : Cellular and Molecular Biology. 49, 2, p. 307 - 317 11 p.

Research output: Contribution to journalArticleResearchpeer-review

7 Citations (Scopus)

Formation of assemblies on cell membranes by secreted proteins: molecular studies of free lambda light chain aggregates found on the surface of myeloma cells

Hutchinson, A. T., Malik, A., Berkahn, M. B., Agostino, M. J., To, J., Tacchi, J. L., Djordjevic, S. P., Turnbull, L., Whitchurch, C. B., Edmundson, A. B., Jones, D. R., Raison, R. L. & Ramsland, P. A., 2013, In : Biochemical Journal. 454, 3, p. 479 - 489 11 p.

Research output: Contribution to journalArticleResearchpeer-review

16 Citations (Scopus)

Free ig light chains interact with sphingomyelin and are found on the surface of myeloma plasma cells in an aggregated form

Hutchinson, A., Ramsland, P., Jones, D., Agostino, M., Lund, M., Jennings, C., Bockhorni, V., Yuriev, E., Edmundson, A. & Raison, R., 2010, In : Journal of Immunology. 185, p. 4179 - 4188 10 p.

Research output: Contribution to journalArticleResearchpeer-review

29 Citations (Scopus)

Global population structure of the genes encoding the Malaria vaccine candidate, Plasmodium vivax Apical Membrane Antigen 1 (PvAMA1)

Arnott, A., Mueller, I., Ramsland, P. A., Siba, P., Reeder, J. C. & Barry, A. E., 2013, In : PLoS Neglected Tropical Diseases. 7, 10, 14 p., e2506.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
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58 Citations (Scopus)

HIV-1 escape from the CCR5 antagonist maraviroc associated with an altered and less-efficient mechanism of gp120-CCR5 engagement that attenuates macrophage tropism

Roche, M., Jakobsen, M., Sterjovski, J., Ellett, A., Posta, F., Lee, B., Jubb, B., Westby, M., Lewin, S. R., Ramsland, P. A., Churchill, M. & Gorry, P. R., 2011, In : Journal of Virology. 85, 9, p. 4330 - 4342 13 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
25 Citations (Scopus)

Identification of preferred carbohydrate binding modes in xenoreactive antibodies by combining conformational filters and binding site maps

Agostino, M., Sandrin, M., Thompson, P., Yuriev, E. & Ramsland, P., 2010, In : Glycobiology. 20, 6, p. 724 - 735 12 p.

Research output: Contribution to journalArticleResearchpeer-review

6 Citations (Scopus)

Identification of residues involved in NS2 homodimerization and elucidation of their impact on the HCV life cycle

Gorzin, A. A., Ramsland, P. A., Tachedjian, G. & Gowans, E. J., 2012, In : Journal of Viral Hepatitis. 19, 3, p. 189 - 198 10 p.

Research output: Contribution to journalArticleResearchpeer-review

7 Citations (Scopus)

Immunoglobulin Cross-Reactivity Examined by Library Screening, Crystallography and Docking Studies

Ramsland, P. A., Yuriev, E. & Edmundson, A. B., 2001, In : Combinatorial Chemistry and High Throughput Screening. 4, 5, p. 397 - 408 12 p.

Research output: Contribution to journalArticleResearchpeer-review

99 Citations (Scopus)

Improvements, trends, and new ideas in molecular docking: 2012-2013 in review

Yuriev, E., Holien, J. & Ramsland, P. A., 2015, In : Journal of Molecular Recognition. 28, 10, p. 581-604 24 p.

Research output: Contribution to journalArticleResearchpeer-review

24 Citations (Scopus)

Inhibition of destructive autoimmune arthritis in FcgRIIa transgenic mice by small chemical entities

Pietersz, G. A., Mottram, P. L., van de Velde, N. C., Sardjono, C. T., Esparon, S. E., Ramsland, P. A., Moloney, G., Baell, J. B., McCarthy, T. D., Matthews, B. R., Powell, M. & Hogarth, P. M., 2009, In : Immunology and Cell Biology. 87, 1, p. 3 - 12 10 p.

Research output: Contribution to journalArticleResearchpeer-review

15 Citations (Scopus)

Insights into the immunological properties of intrinsically disordered malaria proteins using proteome scale predictions

Guy, A. J., Irani, V. R., MacRaild, C. A., Anders, R. F., Norton, R. S., Beeson, J. G., Richards, J. S. & Ramsland, P. A., 2015, In : PLoS ONE. 10, 10, 22 p., e0141729.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
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27 Citations (Scopus)

In silico analysis of antibody-carbohydrate interactions and its application to xenoreactive antibodies

Agostino, M. J., Sandrin, M. S., Thompson, P., Yuriev, E. & Ramsland, P. A., 2009, In : Molecular Immunology. 47, 2-3, p. 233 - 246 14 p.

Research output: Contribution to journalArticleResearchpeer-review

9 Citations (Scopus)

Interaction of human, rat, and mouse immunoglobulin A (IgA) with staphylococcal superantigen-like 7 (SSL7) decoy protein and leukocyte IgA receptor

Wines, B. D., Ramsland, P. A., Trist, H. M., Gardam, S., Brink, R., Fraser, J. D. & Hogarth, P. M., 23 Sep 2011, In : Journal of Biological Chemistry. 286, 38, p. 33118-33124 7 p.

Research output: Contribution to journalArticleResearchpeer-review

165 Citations (Scopus)

Latest developments in molecular docking: 2010-2011 in review

Yuriev, E. & Ramsland, P. A., 2013, In : Journal of Molecular Recognition. 26, 5, p. 215 - 239 25 p.

Research output: Contribution to journalArticleResearchpeer-review

19 Citations (Scopus)

Longitudinal analysis of CCR5 and CXCR4 usage in a cohort of antiretroviral therapy-naive subjects with progressive HIV-1 subtype C infection

Jakobsen, M. R., Cashin, K., Roche, M., Sterjovski, J., Ellett, A., Borm, K., Flynn, J. K., Erikstrup, C., Gouillou, M., Gray, L. R., Saksena, N. K., Wang, B., Purcell, D. F., Kallestrup, P., Zinyama-Gutsire, R., Gomo, E., Ullum, H., Ostergaard, L., Lee, B., Ramsland, P. A. & 2 others, Churchill, M. & Gorry, P. R., 2013, In : PLoS ONE. 8, 6, 13 p., e65950.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
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26 Citations (Scopus)

Macrophage-tropic HIV-1 variants from brain demonstrate alterations in the way gp120 engages both CD4 and CCR5

Salimiseyedabad, H., Roche, M., Webb, N., Gray, L. R., Chikere, K., Sterjovski, J., Ellett, A., Wesselingh, S. L., Ramsland, P. A., Lee, B., Churchill, M. & Gorry, P. R., 2013, In : Journal of leukocyte biology. 93, 1, p. 113 - 126 14 p.

Research output: Contribution to journalArticleResearchpeer-review

24 Citations (Scopus)

Mannosylation of mutated MBP83-99 peptides diverts immune responses from Th1 to Th2

Katsara, M., Yuriev, E., Ramsland, P. A., Deraos, G., Tselios, T., Matsoukas, J. & Apostolopoulos, V., 2008, In : Molecular Immunology. 45, 13, p. 3661 - 3670 10 p.

Research output: Contribution to journalArticleResearchpeer-review