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Research Output 1987 2019

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2019

Aspirin in coronary artery surgery: 1-year results of the Aspirin and Tranexamic Acid for Coronary Artery Surgery trial

Myles, P. S., Smith, J. A., Kasza, J., Silbert, B., Jayarajah, M., Painter, T., Cooper, D. J., Marasco, S., McNeil, J., Bussières, J. S., McGuinness, S., Chan, M. T. V., Wallace, S., Forbes, A. & for the ATACAS investigators and the ANZCA Clinical Trials Network, Feb 2019, In : Journal of Thoracic and Cardiovascular Surgery. 157, 2, p. 633-640

Research output: Contribution to journalArticleResearchpeer-review

A survey of anaesthetists’ use of tranexamic acid in noncardiac surgery

Painter, T. W., McIlroy, D., Myles, P. S. & Leslie, K., 1 Feb 2019, In : Anaesthesia and intensive care. 47, 1, p. 76-84 9 p.

Research output: Contribution to journalArticleResearchpeer-review

Days at Home after Surgery: An Integrated and Efficient Outcome Measure for Clinical Trials and Quality Assurance

Bell, M., Eriksson, L. I., Svensson, T., Hallqvist, L., Granath, F., Reilly, J. & Myles, P. S., 27 Apr 2019, (Accepted/In press) In : eClinical Medicine. p. 1-9 9 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access

Evidence for compromised data integrity in studies of liberal peri-operative inspired oxygen

Myles, P. S., Carlisle, J. B. & Scarr, B., 1 May 2019, In : Anaesthesia. 74, 5, p. 573–584 12 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
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Perioperative Fluid Therapy for Major Surgery

Miller, T. E. & Myles, P. S., 1 May 2019, In : Anesthesiology. 130, 5, p. 825-832 8 p.

Research output: Contribution to journalArticleOtherpeer-review

Postoperative critical care and high-acuity care provision in the United Kingdom, Australia, and New Zealand

Wong, D. J. N., Popham, S., Wilson, A. M., Barneto, L. M., Lindsay, H. A., Farmer, L., Saunders, D., Wallace, S., Campbell, D., Myles, P. S., Harris, S. K., Moonesinghe, S. R. & the SNAP-2: EPICCS collaborators, Apr 2019, In : British Journal of Anaesthesia. 122, 4, p. 460-469 10 p.

Research output: Contribution to journalArticleResearchpeer-review

Practice patterns and perceptions of Australian and New Zealand anaesthetists towards perioperative oxygen therapy

Frei, D. R., Beasley, R., Campbell, D., Leslie, K., Merry, A. F., Moore, M., Myles, P. S., Ruawai-Hamilton, L., Short, T. G. & Young, P. J., 24 May 2019, (Accepted/In press) In : Anaesthesia and intensive care. 7 p.

Research output: Contribution to journalArticleResearchpeer-review

Tranexamic acid in coronary artery surgery: One-year results of the Aspirin and Tranexamic Acid for Coronary Artery Surgery (ATACAS) trial

Myles, P. S., Smith, J. A., Kasza, J., Silbert, B., Jayarajah, M., Painter, T., Cooper, D. J., Marasco, S., McNeil, J., Bussières, J. S., McGuinness, S., Byrne, K., Chan, M. T. V., Landoni, G., Wallace, S., Forbes, A. & ATACAS investigators and the ANZCA Clinical Trials Network, 1 Feb 2019, In : Journal of Thoracic and Cardiovascular Surgery. 157, 2, p. 644-652 18 p.

Research output: Contribution to journalArticleResearchpeer-review

Tranexamic acid modulates the immune response and reduces postsurgical infection rates

Draxler, D. F., Yep, K., Hanafi, G., Winton, A., Daglas, M., Ho, H., Sashindranath, M., Wutzlhofer, L. M., Forbes, A., Goncalves, I., Tran, H. A., Wallace, S., Plebanski, M., Myles, P. S. & Medcalf, R. L., 28 May 2019, In : Blood Advances. 3, 10, p. 1598-1609 12 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
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Using the 6-minute walk test to predict disability-free survival after major surgery

Shulman, M. A., Cuthbertson, B. H., Wijeysundera, D. N., Pearse, R. M., Thompson, B., Torres, E., Ambosta, A., Wallace, S., Farrington, C., Myles, P. S. & on behalf of the Measurement of Exercise Tolerance for Surgery Study Investigators, 1 Jan 2019, In : British Journal of Anaesthesia. 122, 1, p. 111-119 9 p.

Research output: Contribution to journalArticleResearchpeer-review

2018

Assessment of functional capacity before major non-cardiac surgery: an international, prospective cohort study

Wijeysundera, D. N., Pearse, R. M., Shulman, M. A., Abbott, T. E. F., Torres, E., Ambosta, A., Croal, B. L., Granton, J. T., Thorpe, K. E., Grocott, M. P. W., Farrington, C., Myles, P. S., Cuthbertson, B. H. & on behalf of the METS study investigators, 30 Jun 2018, In : The Lancet. 391, 10140, p. 2631-2640 10 p.

Research output: Contribution to journalArticleResearchpeer-review

Clinical indicators for reporting the effectiveness of patient quality and safety-related interventions: A protocol of a systematic review and Delphi consensus process as part of the international Standardised Endpoints for Perioperative Medicine initiative (StEP)

Bampoe, S., Cook, T., Fleisher, L., Grocott, M. P. W., Neuman, M., Story, D., Myles, P. & Haller, G., 1 Nov 2018, In : BMJ Open. 8, 11, 8 p., e023427.

Research output: Contribution to journalArticleOtherpeer-review

Open Access

Dexamethasone for Cardiac Surgery trial (DECS-II): Rationale and a novel, practice preference-randomized consent design

Myles, P. S., Dieleman, J. M., Forbes, A., Heritier, S. & Smith, J. A., 1 Oct 2018, In : American Heart Journal. 204, p. 52-57 6 p.

Research output: Contribution to journalArticleOtherpeer-review

Implication of major adverse postoperative events and myocardial injury on disability and survival: A planned subanalysis of the ENIGMA-II trial

Scott Beattie, W., Wijeysundera, D. N., Chan, M. T. V., Peyton, P. J., Leslie, K., Paech, M., Sessler, D. I., Wallace, S., Myles, P. S. & on behalf of the ANZCA Clinical Trials Network for the ENIGMA-II Investigators, 1 Jan 2018, In : Anesthesia and Analgesia. 127, 5, p. 1118-1126 9 p.

Research output: Contribution to journalArticleResearchpeer-review

Is Conventional Bypass for Coronary Artery Bypass Graft Surgery a Misnomer?

Likosky, D. S., Baker, R. A., Newland, R. F., Paugh, T. A., Dickinson, T. A., Fitzgerald, D., Goldberg, J. B., Mellas, N. B., Merry, A. F., Myles, P. S., Paone, G., Shann, K. G., Ottens, J., Willcox, T. W. & International Consortium for Evidence-Based Perfusion, the PERForm Registry, the Australian and New Zealand Collaborative Perfusion Registry (ANZCPR), and the Michigan Society of Thoracic and Cardiovascular Surgeons Quality Collaborative, 1 Dec 2018, In : Journal of Extra-Corporeal Technology. 50, 4, p. 225-230 6 p.

Research output: Contribution to journalArticleResearchpeer-review

Predictors of return to work in survivors of critical illness

Hodgson, C. L., Haines, K. J., Bailey, M., Barrett, J., Bellomo, R., Bucknall, T., Gabbe, B. J., Higgins, A. M., Iwashyna, T. J., Hunt-Smith, J., Murray, L. J., Myles, P. S., Ponsford, J., Pilcher, D., Udy, A. A., Walker, C., Young, M., (Jamie) Cooper, D. J. & ICU-Recovery Investigators, 1 Dec 2018, In : Journal of Critical Care. 48, p. 21-25 5 p.

Research output: Contribution to journalArticleResearchpeer-review

Restrictive versus liberal fluid therapy for major abdominal surgery

Myles, P. S., Bellomo, R., Corcoran, T., Forbes, A., Peyton, P., Story, D., Christophi, C., Leslie, K., McGuinness, S., Parke, R., Serpell, J., Chan, M. T. V., Painter, T., McCluskey, S., Minto, G. & Wallace, S., 14 Jun 2018, In : New England Journal of Medicine. 378, 24, p. 2263-2274 12 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
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Six-Month Outcomes After High-Risk Coronary Artery Bypass Graft Surgery and Preoperative Intra-aortic Balloon Counterpulsation Use: An Inception Cohort Study

Litton, E., Bass, F., Delaney, A., Hillis, G., Marasco, S., McGuinness, S., Myles, P. S., Reid, C. M., Smith, J. A. & the PINBALL study investigators and the ANZICS CTG, 1 Oct 2018, In : Journal of Cardiothoracic and Vascular Anesthesia. 32, 5, p. 2067-2073 7 p.

Research output: Contribution to journalArticleResearchpeer-review

Systematic review and consensus definitions for the Standardised Endpoints in Perioperative Medicine (StEP) initiative: renal endpoints

McIlroy, D. R., Bellomo, R., Billings, F. T., Karkouti, K., Prowle, J. R., Shaw, A. D. & Myles, P. S., 1 Nov 2018, In : British Journal of Anaesthesia. 121, 5, p. 1013-1024 12 p.

Research output: Contribution to journalArticleResearchpeer-review

The early in-vivo effects of a single anti-emetic dose of dexamethasone on innate immune cell gene expression and activation in healthy volunteers

Bain, C. R., Draxler, D. F., Taylor, R., Wallace, S., Gouldthorpe, O., Corcoran, T. B., Myles, P. S., L. Medcalf, R. & Bozaoglu, K., Aug 2018, In : Anaesthesia. 73, 8, p. 955-966 12 p.

Research output: Contribution to journalArticleResearchpeer-review

2017

Age and other perioperative risk factors for postoperative systemic inflammatory response syndrome after cardiac surgery

Dieleman, J. M., Peelen, L. M., Coulson, T. G., Tran, L., Reid, C. M., Smith, J. A., Myles, P. S. & Pilcher, D., 1 Oct 2017, In : British Journal of Anaesthesia. 119, 4, p. 637-644 8 p.

Research output: Contribution to journalArticleResearchpeer-review

Development and validation of Arabic version of the postoperative quality of recovery-40 questionnaire

Terkawi, A. S., Myles, P. S., Riad, W., Nassar, S. N., Mahmoud, M., AlKahtani, G. J., Sala, F. J., Abdulrahman, A., Doais, K. S., Terkawi, R. S. & Tsang, S., 1 May 2017, In : Saudi Journal of Anaesthesia. 11, 5, p. S40-S52 13 p.

Research output: Contribution to journalArticleResearchpeer-review

Intraoperative dexamethasone does not increase the risk of postoperative wound infection: A propensity score-matched post hoc analysis of the ENIGMA-II trial (EnDEX)

Corcoran, T., Kasza, J., Short, T. G., O'Loughlin, E., Chan, M. T. V., Leslie, K., Forbes, A., Paech, M., Myles, P. & ENIGMA-II investigators, 1 Feb 2017, In : British Journal of Anaesthesia. 118, 2, p. 190-199 10 p.

Research output: Contribution to journalArticleResearchpeer-review

Intra-operative protective mechanical ventilation in lung transplantation: a randomised, controlled trial

Verbeek, G. L., Myles, P. S., Westall, G. P., Lin, E., Hastings, S. L., Marasco, S. F., Jaffar, J. & Meehan, A. C., 1 Aug 2017, In : Anaesthesia. 72, 8, p. 993-1004 12 p.

Research output: Contribution to journalArticleResearchpeer-review

Measuring acute postoperative pain using the visual analog scale: The minimal clinically important difference and patient acceptable symptom state

Myles, P. S., Myles, D. B., Galagher, W., Boyd, D., Macdonald, N. & Dennis, A. A., 2017, In : British Journal of Anaesthesia. 118, 3, p. 424-429 6 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
File

Patient and community attitudes toward perioperative biobanking and genomic research

Liddell, J., Bain, C. & Myles, P. S., 1 May 2017, In : Anaesthesia and intensive care. 45, 3, p. 384-395 12 p.

Research output: Contribution to journalArticleResearchpeer-review

Restrictive versus liberal fluid therapy in major abdominal surgery (RELIEF): Rationale and design for a multicentre randomised trial

Myles, P., Bellomo, R., Corcoran, T., Forbes, A., Wallace, S., Peyton, P., Christophi, C., Story, D., Leslie, K., Serpell, J., McGuinness, S., Parke, R., Australian and New Zealand College of Anaesthetists Clinical Trials Network & Australian and New Zealand Intensive Care Society Clinical Trials Group, 1 Mar 2017, In : BMJ Open. 7, 3, 9 p., e015358.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
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SNAP-2 EPICCS: The second Sprint National Anaesthesia Project - EPIdemiology of Critical Care after Surgery: Protocol for an international observational cohort study

Moonesinghe, S. R., Wong, D. J. N., Farmer, L., Shawyer, R. & Myles, P. S., 1 Sep 2017, In : BMJ Open. 7, 9, 7 p., e017690.

Research output: Contribution to journalArticleOtherpeer-review

Open Access
File

The impact of disability in survivors of critical illness

Hodgson, C. L., Udy, A. A., Bailey, M., Barrett, J., Bellomo, R., Bucknall, T., Gabbe, B. J., Higgins, A. M., Iwashyna, T. J., Hunt-Smith, J., Murray, L. J., Myles, P. S., Ponsford, J., Pilcher, D., Walker, C., Young, M. & Cooper, D. J., 1 Jul 2017, In : Intensive Care Medicine. 43, 7, p. 992-1001 10 p.

Research output: Contribution to journalArticleResearchpeer-review

Tranexamic acid in patients undergoing coronary-artery surgery

Myles, P. S., Smith, J. A., Forbes, A., Silbert, B. & the ATACAS Investigators of the ANZCA Clinical Trials Network, 12 Jan 2017, In : New England Journal of Medicine. 376, 2, p. 136-148 13 p.

Research output: Contribution to journalArticleResearchpeer-review

Validation of days at home as an outcome measure after surgery: A prospective cohort study in Australia

Myles, P. S., Shulman, M. A., Heritier, S., Wallace, S., McIlroy, D. R., McCluskey, S., Sillar, I. & Forbes, A., 1 Aug 2017, In : BMJ Open. 7, 8, e015828.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
File
2016

Chronic postsurgical pain in the evaluation of nitrous oxide in the gas mixture for anaesthesia (ENIGMA)-II trial

Chan, M. T. V., Peyton, P. J., Myles, P. S., Leslie, K., Kasza, J., Paech, M. J., Beattie, W. S., Sessler, D. I., Forbes, A. B., Forbes, A., Wallace, S., Chen, Y., Tian, Y., Wu, W. K. K. & Australian and New Zealand College of Anaesthetists Clinical Trials Network for the ENIGMA-II investigators, 12 Dec 2016, In : British Journal of Anaesthesia. 117, 6, p. 801-811 11 p.

Research output: Contribution to journalArticleResearchpeer-review

Global patient outcomes after elective surgery: Prospective cohort study in 27 low-, middle- and high-income countries

Shulman, M., Myles, P. & The International Surgical Outcomes Study Group, 1 Nov 2016, In : British Journal of Anaesthesia. 117, 5, p. 601-609 9 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
File

Measurement of Exercise Tolerance before Surgery (METS) study: A protocol for an international multicentre prospective cohort study of cardiopulmonary exercise testing prior to major non-cardiac surgery

Wijeysundera, D. N., Pearse, R. M., Shulman, M. A., Abbott, T. E. F., Torres, E., Croal, B. L., Granton, J. T., Thorpe, K. E., Grocott, M. P. W., Farrington, C., Myles, P. S., Cuthbertson, B. H. & on behalf of the METS study investigators, 2016, In : BMJ Open. 6, 3, 10 p., e010359.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
File

Minimal clinically important difference for three quality of recovery scales

Myles, P. S., Myles, D. B., Galagher, W., Chew, C., Macdonald, N. & Dennis, A., 1 Jul 2016, In : Anesthesiology. 125, 1, p. 39-45 7 p.

Research output: Contribution to journalArticleResearchpeer-review

Mortality of emergency general surgical patients and associations with hospital structures and processes

Ozdemir, B. A., Sinha, S., Karthikesalingam, A., Poloniecki, J. D., Pearse, R. M., Grocott, M. P. W., Thompson, M. M., Holt, P. J. E. & Myles, P. S. (ed.), 1 Jan 2016, In : British Journal of Anaesthesia. 116, 1, p. 54-62 9 p.

Research output: Contribution to journalArticleOtherpeer-review

Perioperative management of patients treated with angiotensin-converting enzyme inhibitors and angiotensin II receptor blockers: A quality improvement audit

Vijay, A., Grover, A., Coulson, T. G. & Myles, P. S., 1 May 2016, In : Anaesthesia and intensive care. 44, 3, p. 346-352 7 p.

Research output: Contribution to journalArticleResearchpeer-review

Restrictive versus liberal transfusion strategy in the perioperative and acute care settings: A context-specific systematic review and meta-analysis of randomized controlled trials

Hovaguimian, F. & Myles, P. S., 1 Jul 2016, In : Anesthesiology. 125, 1, p. 46-61 16 p.

Research output: Contribution to journalArticleResearchpeer-review

Serious adverse event reporting in investigator-initiated clinical trials

Wallace, S., Myles, P. S., Zeps, N. & Zalcberg, J. R., 4 Apr 2016, In : Medical Journal of Australia. 204, 6, p. 231-233.e1 4 p.

Research output: Contribution to journalArticleOtherpeer-review

Severe nausea and vomiting in the evaluation of nitrous oxide in the gas mixture for Anesthesia II trial

Myles, P. S., Chan, M. T. V., Kasza, J., Paech, M. J., Leslie, K., Peyton, P. J., Sessler, D. I., Haller, G., Beattie, W. S., Osborne, C., Sneyd, J. R. & Forbes, A., 1 May 2016, In : Anesthesiology. 124, 5, p. 1032-1040 9 p.

Research output: Contribution to journalArticleResearchpeer-review

Stopping vs. continuing aspirin before coronary artery surgery

Myles, P. S., Smith, J. A., Forbes, A., Silbert, B., Jayarajah, M., Painter, T., Cooper, D. J., Marasco, S., McNeil, J., Bussières, J. S. & Wallace, S., 25 Feb 2016, In : New England Journal of Medicine. 374, 8, p. 728-737 10 p.

Research output: Contribution to journalArticleResearchpeer-review

2015

Acute alcohol intoxication and bispectral index monitoring

Gerstman, M. D., Merry, A. F., McIlroy, D. R., Hannam, J. A., Mitchell, S. J. & Myles, P. S., 2015, In : Acta Anaesthesiologica Scandinavica. 59, 8, p. 1015 - 1021 7 p.

Research output: Contribution to journalArticleResearchpeer-review

An enhanced recovery after surgery program for hip and knee arthroplasty

Christelis, N., Wallace, S., Sage, C., Babitu, U., Liew, S. M., Dugal, J., Nyulasi, I., Mutalima, N., Tran, T. & Myles, P. S., 2015, In : Medical Journal of Australia. 202, 7, p. 363 - 369 7 p.

Research output: Contribution to journalArticleResearchpeer-review

Apnea after Awake Regional and General Anesthesia in Infants: The General Anesthesia Compared to Spinal Anesthesia Study-Comparing Apnea and Neurodevelopmental Outcomes, a Randomized Controlled Trial

Davidson, A. J., Morton, N. S., Arnup, S. J., De Graaff, J. C., Disma, N., Withington, D. E., Frawley, G., Hunt, R. W., Hardy, P., Khotcholava, M., Von Ungern Sternberg, B. S., Wilton, N., Tuo, P., Salvo, I., Ormond, G., Stargatt, R., Locatelli, B. G., McCann, M. E., General Anesthesia Compared to Spinal Anesthesia (GAS) Study Consortium, Sheppard, S. & 4 othersHartmann, P., Myles, P., Carlin, J. & Leslie, K., 20 Jul 2015, In : Anesthesiology. 123, 1, p. 38-54 17 p.

Research output: Contribution to journalArticleResearchpeer-review

Aspirin and coronary artery surgery: a systematic review and meta-analysis

Hastings, S., Myles, P. S. & McIlroy, D. R., 2015, In : British Journal of Anaesthesia. 3, 3, p. 376 - 385 10 p.

Research output: Contribution to journalArticleResearchpeer-review

Does the use of statins improve outcomes in coronary artery bypass graft surgery?

McIlroy, D. R. & Myles, P. S., 2015, In : Expert Review of Cardiovascular Therapy. 13, 12, p. 1285 - 1288 4 p.

Research output: Contribution to journalArticleOtherpeer-review

ENIGMA-II, and can an old dog be taught new tricks?

Myles, P., 2015, In : Southern African Journal of Anaesthesia and Analgesia. 21, 1, p. 68 - 68 1 p.

Research output: Contribution to journalArticleOtherpeer-review

Hyperbaric Oxygen in Lower Limb Trauma (HOLLT); protocol for a randomised controlled trial

Millar, I. L., McGinnes, R. A., Williamson, O. D., Lind, F., Jansson, K-A., Hajek, M., Smart, D., Fernandes, T., Miller, R. D., Myles, P. S. & Cameron, P., 2015, In : BMJ Open. 5, 6, p. 1 - 10 10 p., e008381.

Research output: Contribution to journalArticleOther

Interrelationship of preoperative anemia, intraoperative anemia, and red blood cell transfusion as potentially modifiable risk factors for acute kidney injury in cardiac surgery: a historical multicentre cohort study

Karkouti, K., Grocott, H. P., Hall, R. I., Jessen, M. E., Kruger, C., Lerner, A. B., MacAdams, C., Mazer, C. D., de Medicis, E., Myles, P. S., Ralley, F., Rheault, M. R., Rochon, A., Slaughter, M. S., Sternlicht, A., Syed, S. & Waters, T., 2015, In : Canadian Journal of Anaesthesia-Journal Canadien D Anesthesie. 62, 4, p. 377 - 384 8 p.

Research output: Contribution to journalArticleResearchpeer-review