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Personal profile


Professor Paul Lacaze is a pioneering researcher in public health genomics and population DNA screening. He holds a NHMRC Investigator Leadership grant and Heart Foundation Future Leader Fellowship and is the Cheif Investigator A (CIA) of the landmark DNA Screen national pilot study, offering preventive population DNA screening to 10,000 healthy adults for medically actionable conditions. Lacaze is also CIA of the Australian Genetics and Life Insurance Moratorium: Monitoring the Effectiveness and Response (A-GLIMMER) project. Lacaze leads the genomics research program for the ASPREE study, Australia’s largest randomised trial and genomic cohort of ageing. Lacaze is one of few Australian researchers to have designed, executed and analysed large genomic cohort studies (N > 10,000) within his own group. He also leads a parallel research stream focused on ethical, legal, social, health-economic and policy aspects of human genomics. He is an Affiliate Faculty Member, Massachusetts General Hospital, Boston, USA, an Honorary Fellow, Adult Genomic Medicine, Royal Melbourne Hospital, and a visiting Scientist, Garvan Institute of Medical Research. 

Community service

Professor Lacaze regularly works with patient groups to deliver patient-centred research and advocate for issues in Australia. This includes working with the Familial Hypercholesterolemia Network Australia, Pink Hope, Lynch Syndrome Australia and Rare Voices Australia. Lacaze founded the Australian Genetic Non-Discrimination Working Group, and on behalf of the group, provided evidence to the 2017 Parliamentary inquiry into life insurance (Canberra). This has led to a moratorium on the use of genetic test results in Australian life insurance, is now directly benefiting Australian consumers, clinicians and researchers. Lacaze was recently selected to represent the Australian Cardiovascular Alliance as an EMCR at the Science Meets Parliament event in Canberra. Lacaze serves on the Scientific and Medical Advisory Committee of Rare Voices Australia.

Expertise related to UN Sustainable Development Goals

In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):

  • SDG 3 - Good Health and Well-being
  • SDG 9 - Industry, Innovation, and Infrastructure
  • SDG 11 - Sustainable Cities and Communities

Education/Academic qualification

Genomics, PhD, Genomics, immunology, virology, University of Edinburgh

Award Date: 20 Apr 2011

Systems Biology, MSc, University of Edinburgh


Award Date: 30 Sept 2005

Science, BSc, Genomics & Biotechnology, University of Melbourne


Award Date: 30 Nov 2003

International Baccalaureate, Ivanhoe Grammar School

Award Date: 30 Dec 2000

Research area keywords

  • Public Health
  • Human genomics
  • Clinical translation
  • Preventive Medicine
  • Genetics
  • population genetics and genomics
  • Ageing
  • Dementia
  • Cancer
  • Cardiovascular Disease
  • coronary heart disease