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Research Output 1975 2019

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Article
2004

Akt phosphorylation and NFactivation are counterregulated under conditions of oxidative stress

Taylor, J. M., Crack, P. J., Gould, J. A., Ali, U., Hertzog, P. J. & Iannello, R. C., 2004, In : Experimental Cell Research. 300, p. 463 - 475 13 p.

Research output: Contribution to journalArticleResearchpeer-review

20 Citations (Scopus)

Akt phosphorylation and NFκB activation are counterregulated under conditions of oxidative stress

Taylor, J. M., Crack, P. J., Gould, J. A., Ali, U., Hertzog, P. J. & Iannello, R. C., 1 Nov 2004, In : Experimental Cell Research. 300, 2, p. 463-475 13 p.

Research output: Contribution to journalArticleResearchpeer-review

30 Citations (Scopus)

A major site of expression of the ets transcription factor Elf5 is epithelia of exocrine glands

Lapinskas, E. J., Palmer, J., Ricardo, S. D., Hertzog, P. J., Hammacher, A. & Pritchard, M. A., 2004, In : Histochemistry and Cell Biology. 122, 6, p. 521 - 526 6 p.

Research output: Contribution to journalArticleResearchpeer-review

135 Citations (Scopus)

Characterization of the type I interferon locus and identification of novel genes

Hardy, M., Owczarek, C. M., Jermiin, L. S., Ejdeback, M. & Hertzog, P. J., 2004, In : Genomics. 84, 2, p. 331 - 345 15 p.

Research output: Contribution to journalArticleResearchpeer-review

32 Citations (Scopus)

Detailed mapping of the ERG-ETS2 interval of human chromosome 21 and comparison with the region of conserved synteny on mouse chromosome 16

Owczarek, C. M., Portbury, K. J., Hardy, M., O'leary, D., Kudoh, J., Shibuya, K., Shimizu, N., Kola, I. & Hertzog, P. J., 2004, In : Gene. 325, p. 65 - 77 13 p.

Research output: Contribution to journalArticleResearchpeer-review

13 Citations (Scopus)

Differential expression and effects of gp130 cytokines and receptors in prostate cancer cells

Palmer, J., Hertzog, P. J. & Hammacher, A., 1 Nov 2004, In : International Journal of Biochemistry and Cell Biology. 36, 11, p. 2258-2269 12 p.

Research output: Contribution to journalArticleResearchpeer-review

Differential expression and effects of gp 130 cytokines and receptors in prostate cancer cells

Palmer, J., Hertzog, P. J. & Hammacher, A., 2004, In : International Journal of Biochemistry and Cell Biology. 36, p. 2258 - 2269 12 p.

Research output: Contribution to journalArticleResearchpeer-review

55 Citations (Scopus)

Fibroblasts derived from Gpx1 knockout mice display senescent-like features and are susceptible to H2O2-mediated cell death

De Haan, J. B., Bladier, C., Lotfi-Miri, M., Taylor, J., Hutchinson, P., Crack, P. J., Hertzog, P. & Kola, I., 1 Jan 2004, In : Free Radical Biology and Medicine. 36, 1, p. 53-64 12 p.

Research output: Contribution to journalArticleResearchpeer-review

29 Citations (Scopus)

Generation and characterization of neuregulin-2-deficient mice

Britto, J. M., Lukehurst, S., Weller, R., Fraser, C., Qiu, Y., Hertzog, P. & Busfield, S. J., 1 Sep 2004, In : Molecular and Cellular Biology. 24, 18, p. 8221-8226 6 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access

Interferon- : An overview of signals, mechanisms and functions

Schroder, K., Hertzog, P. J., Ravasi, T. & Hume, D. A., 2004, In : Journal of leukocyte biology. 75, 2, p. 163 - 189 27 p.

Research output: Contribution to journalArticleResearchpeer-review

Mal interacts with tumor necrosis factor receptor-associated factor (TRAF)-6 to mediate NF-kB activation by Toll-like receptor (TLR)-2 and TLR4

Mansell, A. S., Brint, E., Gould, J. A., O'Neill, L. & Hertzog, P. J., 2004, In : Journal of Biological Chemistry. 279, 36, p. 37227 - 37230 4 p.

Research output: Contribution to journalArticleResearchpeer-review

87 Citations (Scopus)

Mal interacts with tumor necrosis factor receptor-associated factor (TRAF)-6 to mediate NF-κB activation by Toll-like receptor (TLR)-2 and TLR4

Mansell, A., Brint, E., Gould, J. A., O'Neill, L. A. & Hertzog, P. J., 3 Sep 2004, In : Journal of Biological Chemistry. 279, 36, p. 37227-37230 4 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access

The ETS transcription factor GABPis essential for early embryogenesis

Ristevski, S., O'leary, D., Thornell, A. P., Owen, M. J., Kola, I. & Hertzog, P. J., 2004, In : Molecular and Cellular Biology. 24, 13, p. 5844 - 5849 6 p.

Research output: Contribution to journalArticleResearchpeer-review

91 Citations (Scopus)

The ETS transcription factor GABPα is essential for early embryogenesis

Ristevski, S., O'Leary, D. A., Thornell, A. P., Owen, M. J., Kola, I. & Hertzog, P. J., 1 Jul 2004, In : Molecular and Cellular Biology. 24, 13, p. 5844-5849 6 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access

Tissue-specific overexpression of the HSA21 gene GABP Implications for DS

O'leary, D., Pritchard, M. A., Xu, D., Kola, I., Hertzog, P. J. & Ristevski, S., 2004, In : Biochimica et Biophysica Acta - Reviews on Cancer. 1739, p. 81 - 87 7 p.

Research output: Contribution to journalArticleResearchpeer-review

15 Citations (Scopus)

Tissue-specific overexpression of the HSA21 gene GABPα: Implications for DS

O'Leary, D. A., Pritchard, M. A., Xu, D., Kola, I., Hertzog, P. J. & Ristevski, S., 24 Dec 2004, In : Biochimica et Biophysica Acta - Molecular Basis of Disease. 1739, 1, p. 81-87 7 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
2003

An imbalance in antioxidant defense affects cellular function: The pathophysiological consequences of a reduction in antioxidant defense in the glutathione peroxidase-1 (Gpx1) knockout mouse

De Haan, J. B., Crack, P. J., Flentjar, N. J., Iannello, R. C., Hertzog, P. J. & Kola, I., 2003, In : Redox Report. 8, 2, p. 69 - 79 11 p.

Research output: Contribution to journalArticleResearchpeer-review

12 Citations (Scopus)

Characterization and transcriptional analysis of the mouse chromosome 16 cytokine receptor gene cluster

Hardy, M. P., Sanij, E., Hertzog, P. J. & Owczarek, C. M., 1 Feb 2003, In : Mammalian Genome. 14, 2, p. 105-118 14 p.

Research output: Contribution to journalArticleResearchpeer-review

1 Citation (Scopus)

Characterization of monoclonal antibodies specific to the transcription factor ETS-2 protein

Sanij, E., Scott, B. M., Wilson, T. J., Xu, D., Hertzog, P. J. & Wolvetang, E. J., 2003, In : Immunology Letters. 86, 1, p. 63 - 70 8 p.

Research output: Contribution to journalArticleResearchpeer-review

9 Citations (Scopus)

Chemokine receptor CCR5 is not required for development of experimental autoimmune gastritis

Field, J., Marshall, A. C. J., Hertzog, P. J., Wells, T. N., Alderuccio, F. P. & Toh, B-H., 2003, In : Clinical Immunology. 109, 2, p. 238 - 247 10 p.

Research output: Contribution to journalArticleResearchpeer-review

132 Citations (Scopus)

Dendritic cell precursor populations of mouse blood: Identification of the murine homologues of human blood plasmacytoid pre-DC2 and CD11c+ DC1 precursors

O'Keeffe, M., Hochrein, H., Vremec, D., Scott, B. M., Hertzog, P. J., Tatarczuch, L. & Shortman, K., 15 Feb 2003, In : Blood. 101, 4, p. 1453-1459 7 p.

Research output: Contribution to journalArticleResearchpeer-review

66 Citations (Scopus)

Epstein-Barr virus LMP1 blocks p16INK4a-RB pathway by promoting nuclear export of E2F4/5

Ohtani, N., Brennan, P., Gaubatz, S., Sanij, E., Hertzog, P. J., Wolvetang, E. J., Ghysdael, J., Rowe, M. & Hara, E., 2003, In : Journal of Cell Biology. 162, 2, p. 173 - 183 11 p.

Research output: Contribution to journalArticleResearchpeer-review

30 Citations (Scopus)

Ets1 as a marker of malignant potential in gastric carcinoma

Yong, Y., Zhang, Y-C., Zhang, W-Z., Shen, L-S., Hertzog, P. J., Wilson, T. J. & Xu, D-K., 2003, In : World Journal of Gastroenterology. 9, 10, p. 2154 - 2159 6 p.

Research output: Contribution to journalArticleResearchpeer-review

ETS2 overexpression in transgenic models and in Down syndrome predisposes to apoptosis via the p53 pathway

Wolvetang, E. J., Wilson, T. J., Sanij, E., Busciglio, J., Hatzistavrou, T., Seth, A., Hertzog, P. J. & Kola, I., 2003, In : Human Molecular Genetics. 12, 3, p. 247 - 255 9 p.

Research output: Contribution to journalArticleResearchpeer-review

5 Citations (Scopus)

Generation and characterization of recombinant unmodified and phosphorylatable murine IFN-1 in the methylotropic yeast Pichia pastoris

Trajanovska, S., Owczarek, C. M., Stanton, P. G. & Hertzog, P. J., 2003, In : Journal of Interferon and Cytokine Research. 23, 12, p. 351 - 358 8 p.

Research output: Contribution to journalArticleResearchpeer-review

51 Citations (Scopus)

Glutathione peroxidase-1 contributes to the neuroprotection seen in the superoxide dismutase-1 transgenic mouse in response to ischemia/reperfusion injury

Crack, P. J., Taylor, J. M., De Haan, J. B., Kola, I., Hertzog, P. & Iannello, R. C., 1 Jan 2003, In : Journal of Cerebral Blood Flow and Metabolism. 23, 1, p. 19-22 4 p.

Research output: Contribution to journalArticleResearchpeer-review

38 Citations (Scopus)

Overexpression of the chromosome 21 transcription factor Ets2 induces neuronal apoptosis

Wolvetang, E. J., Bradfield, O. M., Hatzistavrou, T., Crack, P. J., Busciglio, J., Kola, I. & Hertzog, P. J., 2003, In : Neurobiology of Disease. 14, 6, p. 349 - 356 8 p.

Research output: Contribution to journalArticleResearchpeer-review

28 Citations (Scopus)

The chromosome 21 transcription factor ETS2 transactivates the beta-APP promoter: Implications for Down syndrome

Wolvetang, E. J., Bradfield, O. M., Tymms, M. J., Zavarsek, S., Hatzistavrou, T., Kola, I. & Hertzog, P. J., 2003, In : Biochimica et Biophysica Acta - Gene Structure and Expression. 1628, 2, p. 105 - 110 6 p.

Research output: Contribution to journalArticleResearchpeer-review

144 Citations (Scopus)

The interferon in TLR signaling: more than just antiviral

Hertzog, P. J., O'Neill, L. A. & Hamilton, J. A., 2003, In : Trends in Immunology. 24, 10, p. 534 - 539 6 p.

Research output: Contribution to journalArticleResearchpeer-review

14 Citations (Scopus)

Transformation induced by Ewing's sarcoma associated EWS/FLI-1 is suppressed by KRAB/FLI-1

Chan, D., Wilson, T. J., Xu, D., Cowdery, H. E., Sanij, E., Hertzog, P. J. & Kola, I., 2003, In : British Journal of Cancer. 88, p. 137 - 145 9 p.

Research output: Contribution to journalArticleResearchpeer-review

2002
3 Citations (Scopus)

A Human CD2 minigene directs CRE-mediated recombination in T cells in vivo

Wilson, T. J., Cowdery, H. E., Xu, D., Kola, I. & Hertzog, P. J., 2002, In : Genesis. 33, 4, p. 181 - 184 4 p.

Research output: Contribution to journalArticleResearchpeer-review

Endogenous interferon-reduces c expression and blocks IL-4 regulation of TNF production of human monocyte-derived macrophages

Bonder, C. S., Davies, K. VL., Liu, X., Hertzog, P. J., Woodcock, J. M., Finlay-Jones, J. J. & Hart, P. H., 2002, In : Cytokine. 17, 4, p. 187 - 196 10 p.

Research output: Contribution to journalArticleResearchpeer-review

3 Citations (Scopus)

Endogenous interferon-α production by differentiating human monocytes regulates expression and function of the IL-2/IL-4 receptor γ chain

Bonder, C. S., Davies, K. V. L., Liu, X., Hertzog, P. J., Woodcock, J. M., Finlay-Jones, J. J. & Hart, P. H., 1 Jan 2002, In : Cytokine. 17, 4, p. 187-196 10 p.

Research output: Contribution to journalArticleResearchpeer-review

65 Citations (Scopus)

Ets1 is required for p53 transcriptional activity in UV-induced apoptosis in embryonic stem cells

Xu, D., Wilson, T. J., Chan, D., De Luca, E., Zhou, J., Hertzog, P. & Kola, I., 2002, In : EMBO Journal. 21, 15, p. 4081 - 4093 13 p.

Research output: Contribution to journalArticleResearchpeer-review

12 Citations (Scopus)

Ets2 is expressed during morphogenesis of the somite and limb in the mouse embryo

Ristevski, S., Tam, P., Hertzog, P. J. & Kola, I., 2002, In : Mechanisms of Development. 116, 1-Feb, p. 165 - 168 4 p.

Research output: Contribution to journalArticleResearchpeer-review

111 Citations (Scopus)

Inactivation of the transcription factor Elf3 in mice results in dysmorphogenesis and altered differentiation of intestinal epithelium

Ng, A. Y-N., Waring, P., Ristevski, S., Wang, C., Wilson, T. J., Pritchard, M. A., Hertzog, P. J. & Kola, I., 2002, In : Gastroenterology. 122, p. 1455 - 1466 12 p.

Research output: Contribution to journalArticleResearchpeer-review

36 Citations (Scopus)

Mice lacking glutathione peroxidase-1 activity show increased tunel staining and an accelerated inflammatory response in brain following a cold induced injury

Flentjar, N. J., Crack, P. J., Boyd, R., Malin, M. A., De Haan, J. B., Hertzog, P. J., Kola, I. & Iannello, R. C., 2002, In : Experimental Neurology. 177, p. 9 - 20 12 p.

Research output: Contribution to journalArticleResearchpeer-review

311 Citations (Scopus)

Mouse Plasmacytoid Cells: Long-lived Cells, Heterogeneous in Surface Phenotype and Function, that Differentiate Into CD8+ Dendritic Cells Only after Microbial Stimulus

O'Keeffe, M., Hochrein, H., Vremec, D., Caminschi, I., Miller, J. L., Anders, M. L., Wu, L., Mahoud, M. H., Henri, S., Scott, B. M., Hertzog, P. J., Tatarczuch, L. & Shortman, K., 2002, In : Journal of Experimental Medicine. 196, 10, p. 1307 - 1319 13 p.

Research output: Contribution to journalArticleResearchpeer-review

20 Citations (Scopus)

Multiple regions within the promoter of the murine Ifnar-2 gene confer basal and inducible expression

Hardy, M. P., Hertzog, P. & Owczarek, C. M., 2002, In : Biochemical Journal. 365, p. 355 - 367 13 p.

Research output: Contribution to journalArticleResearchpeer-review

2001

A novel member of the STOMATIN/EPB72/mec-2 family, stomatin-like2 (STOML2), is ubiquitously expressed and localizes to HSA chromosome 9p13.1

Owczarek, C. M., Treutlein, H. R., Portbury, K. J., Gulluyan, L. M., Kola, I. & Hertzog, P. J., 2001, In : Cytogenetics and Cell Genetics. 92, p. 196 - 203 8 p.

Research output: Contribution to journalArticleResearchpeer-review

24 Citations (Scopus)

A novel member of the STOMATIN/EPB72/mec-2 family, stomatin-like 2 (STOML2), is ubiquitously expressed and localizes to HSA chromosome 9p13.1

Owczarek, C. M., Treutlein, H. R., Portbury, K. J., Gulluyan, L. M., Kola, I. & Hertzog, P. J., 24 Jul 2001, In : Cytogenetics and Cell Genetics. 92, 3-4, p. 196-203 8 p.

Research output: Contribution to journalArticleResearchpeer-review

Bone disease - Current knowledge and future propects

Lazner, F., Wolvetang, E. J., Lazner, D. & Hertzog, P. J., 2001, In : Current Genomics. 2, 2, p. 91 - 124 34 p.

Research output: Contribution to journalArticleResearchpeer-review

Bone disease - Current knowledge and future prospects

Lazner, F., Wolvetang, E., Lazner, D. & Hertzog, P., 5 Jun 2001, In : Current Genomics. 2, 2, p. 91-124 34 p.

Research output: Contribution to journalArticleResearchpeer-review

7 Citations (Scopus)

Desrt, an AT-rich interaction domain family transcription factor gene, is an early marker for nephrogenic mesoderm and is expressed dynamically during mouse limb development

Ristevski, S., Tam, P., Kola, I. & Hertzog, P. J., 2001, In : Mechanisms of Development. 104, p. 139 - 142 4 p.

Research output: Contribution to journalArticleResearchpeer-review

Differential production of IL-12, IFN-a and IFN-g by mouse dendritic cell subsets

Hochrein, H., Shortman, K., Vremec, D., Scott, B. M., Hertzog, P. J. & O'Keeffe, M., 2001, In : Journal of Immunology. 166, p. 5448 - 5455 8 p.

Research output: Contribution to journalArticleResearchpeer-review

398 Citations (Scopus)

Differential production of IL-12, IFN-α, and IFN-γ by mouse dendritic cell subsets

Hochrein, H., Shortman, K., Vremec, D., Scott, B., Hertzog, P. & O'Keeffe, M., 1 May 2001, In : Journal of Immunology. 166, 9, p. 5448-5455 8 p.

Research output: Contribution to journalArticleResearchpeer-review

40 Citations (Scopus)

Ets-2 is induced by oxidative stress and sensitizes cells to H2O2-induced apoptosis: Implications for Down's syndrome

Sanij, E., Hatzistavrou, T., Hertzog, P. J., Kola, I. & Wolvetang, E. J., 5 Oct 2001, In : Biochemical and Biophysical Research Communications. 287, 4, p. 1003-1008 6 p.

Research output: Contribution to journalArticleResearchpeer-review

78 Citations (Scopus)

Gene targeting of Desrt, a novel ARID class DNA-binding protein, causes growth retardation and abnormal development of reproductive organs

Lahoud, M. H., Ristevski, S., Venter, D. J., Jermiin, L. S., Bertoncello, I., Zavarsek, S., Hasthorpe, S., Drago, J., de Kretser, D. M., Hertzog, P. J. & Kola, I., 2001, In : Genome Research. 11, p. 1327 - 1334 8 p.

Research output: Contribution to journalArticleResearchpeer-review

8 Citations (Scopus)

Identification and characterization of alternatively spliced murine Rgs11 isoforms: genomic structure and gene analysis

Giudice, A., Gould, J., Freeman, K. B., Rastan, S., Hertzog, P. J., Kola, I. & Iannello, R. C., 2001, In : Cytogenetics and Cell Genetics. 94, 3-4, p. 216 - 224 9 p.

Research output: Contribution to journalArticleResearchpeer-review

148 Citations (Scopus)

Increased infarct size and exacerbated apoptosis in the glutathione peroxidase-1 (Gpx-1) knockout mouse brain in response to ischemia/reperfusion injury

Crack, P. J., Taylor, J. M., Flentjar, N. J., De Haan-Klein, J. B., Hertzog, P. J., Iannello, R. C. & Kola, I., 2001, In : Journal of Neurochemistry. 78, p. 1389 - 1399 11 p.

Research output: Contribution to journalArticleResearchpeer-review