If you made any changes in Pure these will be visible here soon.

Research Output 1975 2019

Filter
Article
2012
212 Citations (Scopus)

Silencing of Irf7 pathways in breast cancer cells promotes bone metastasis through immune escape

Bidwell, B., Slaney, C. Y., Withana, N. P., Forster, S., Cao, Y., Loi, S., Andrews, D. M., Mikeska, T., Mangan, N., Samarajiwa, S. A., De Weerd, N. A., Gould, J. A., Argani, P., Muller, A., Smyth, M., Anderson, R., Hertzog, P. J. & Parker, B., 2012, In : Nature Medicine. 18, 8, p. 1224 - 1231 8 p.

Research output: Contribution to journalArticleResearchpeer-review

106 Citations (Scopus)

West Nile virus noncoding subgenomic RNA contributes to viral evasion of the type I interferon-mediated antiviral response

Schuessler, A., Funk, A., Lazear, H. M., Cooper, D. A., Torres, S., Daffis, S., Jha, B. K., Kumagai, Y., Takeuchi, O., Hertzog, P. J., Silverman, R. H., Akira, S., Barton, D. J., Diamond, M. S. & Khromykh, A. A., 2012, In : Journal of Virology. 86, 10, p. 5708 - 5718 11 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
2011
244 Citations (Scopus)

Analysis of microRNA turnover in mammalian cells following Dicer1 ablation

Gantier, M., McCoy, C., Rusinova, I., Saulep, D., Wang, D., Xu, D., Irving, A., Behlke, M., Hertzog, P., Mackay-Fisson, F. & Williams, B., 2011, In : Nucleic Acids Research. 39, 13, p. 5692 - 5703 12 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
35 Citations (Scopus)

Factors determining the spontaneous activation of splenic dendritic cells in culture

Vremec, D., O'Keeffe, M., Wilson, A., Ferrero, I., Koch, U., Radtke, F., Scott, B., Hertzog, P., Villadangos, J. & Shortman, K., 2011, In : Innate Immunity. 17, 3, p. 338 - 352 15 p.

Research output: Contribution to journalArticleResearchpeer-review

77 Citations (Scopus)

HIV infection of dendritic cells subverts the IFN induction pathway via IRF-1 and inhibits type 1 IFN production

Harman, A., Lai, J., Turville, S., Samarajiwa, S., Gray, L. R., Marsden, V., Mercier, S., Jones, K., Nasr, N., Rustagi, A., Cumming, H., Donaghy, H., Mak, J., Gale Jr, M., Churchill, M., Hertzog, P. & Cunningham, A., 2011, In : Blood. 118, 2, p. 298 - 308 11 p.

Research output: Contribution to journalArticleResearchpeer-review

130 Citations (Scopus)

IL-6 trans-signaling modulates TLR4-dependent inflammatory responses via STAT3

Greenhill, C. J., Rose-John, S., Lissilaa, R., Ferlin, W., Ernst, M., Hertzog, P. J., Mansell, A. S. & Jenkins, B. J., 2011, In : Journal of Immunology. 186, 2, p. 1199 - 1208 10 p.

Research output: Contribution to journalArticleResearchpeer-review

39 Citations (Scopus)

Macrophage activation and differentiation signals regulate schlafen-4 gene expression: Evidence for Schlafen-4 as a modulator of myelopoiesis

van Zuylen, W., Garceau, V., Idris, A., Schroder, K., Irvine, K., Lattin, J., Ovchinnikov, D., Perkins, A., Cook, A. D., Hamilton, J., Hertzog, P., Stacey, K., Kellie, S., Hume, D. & Sweet, M., 2011, In : PLoS ONE. 6, 1, 13 p., e15723.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
37 Citations (Scopus)

Naive and activated T cells display differential responsiveness to TL1A that affects Th17 generation, maintenance, and proliferation

Jones, G., Stumhofer, J., Foster, T., Twohig, J., Hertzog, P. J., Topley, N., Williams, A. S., Hunter, C., Jenkins, B. J., Wang, E. & Jones, S. A., 2011, In : FASEB Journal. 25, 1, p. 409 - 419 11 p.

Research output: Contribution to journalArticleResearchpeer-review

6 Citations (Scopus)

Sculpting the immune response to infection

Hertzog, P., Mansell, A., van Driel, I. R. & Hartland, E., 2011, In : Nature Immunology. 12, 7, p. 579 - 582 4 p.

Research output: Contribution to journalArticleOther

81 Citations (Scopus)

Suppressor of cytokine signaling (SOCS) 1 inhibits type I interferon (IFN) signaling via the interferon alpha receptor (IFNAR1)-associated tyrosine kinase Tyk2

Piganis, R., De Weerd, N. A., Gould, J., Schindler, C., Mansell, A., Nicholson, S. & Hertzog, P., 2011, In : Journal of Biological Chemistry. 286, 39, p. 33811 - 33818 8 p.

Research output: Contribution to journalArticleResearchpeer-review

72 Citations (Scopus)

Systems biology of interferon responses

Hertzog, P., Forster, S. & Samarajiwa, S., 2011, In : Journal of Interferon and Cytokine Research. 31, 1, p. 5 - 11 7 p.

Research output: Contribution to journalArticleResearchpeer-review

7 Citations (Scopus)

The Ets transcription factor ELF5 functions as a tumor suppressor in the kidney

Lapinskas, E., Svobodova, S., Davis, I., Cebon, J., Hertzog, P. & Pritchard, M., 2011, In : Twin Research and Human Genetics. 14, 4, p. 316 - 322 7 p.

Research output: Contribution to journalArticleResearchpeer-review

35 Citations (Scopus)

Type I-IFNs control GVHD and GVL responses after transplantation

Robb, R., Kreijveld, E., Kuns, R., Wilson, Y., Olver, S., Don, A., Raffelt, N., De Weerd, N. A., Lineburg, K., Varelias, A., Markey, K., Koyama, M., Clouston, A., Hertzog, P., MacDonald, K. & Hill, G., 2011, In : Blood. 118, 12, p. 3399 - 3409 11 p.

Research output: Contribution to journalArticleResearchpeer-review

64 Citations (Scopus)

Type I interferons suppress CD4{+} T-cell-dependent parasite control during blood-stage Plasmodium infection

Haque, A., Best, S., Ammerdorffer, A., Desbarrieres, L., Montes de Oca, M., Amante, F., de Labastida Rivera, F., Hertzog, P., Boyle, G., Hill, G. & Engwerda, C., 2011, In : European Journal of Immunology. 41, 9, p. 2688 - 2698 11 p.

Research output: Contribution to journalArticleResearchpeer-review

2010
186 Citations (Scopus)

Bacterial membrane vesicles deliver peptidoglycan to NOD1 in epithelial cells

Liaskos, M., Turnbull, L., Carneiro, L., Firth, S. D., Coleman, H. A., Parkington, H. C., Le Bourhis, L., Karrar, A., Viala, J., Mak, J., Hutton, M. L., Davies, J. K., Crack, P. J., Hertzog, P. J., Philpott, D., Girardin, S. E., Whitchurch, C. B. & Ferrero, R. L., 2010, In : Cellular Microbiology. 12, p. 372 - 385 13 p.

Research output: Contribution to journalArticleResearchpeer-review

35 Citations (Scopus)

Cutting edge: Pulmonary Legionella pneumophila is controlled by plasmacytoid dendritic cells but not type I IFN

Ang, D. KY., Oates, C. VL., Schuelein, R., Kelly, M. L., Sansom, F. M., Bourges, D., Boon, L., Hertzog, P. J., Hartland, E. L. & van Driel, I. R., 2010, In : Journal of Immunology. 184, 10, p. 5429 - 5433 5 p.

Research output: Contribution to journalArticleResearchpeer-review

90 Citations (Scopus)

Functional crosstalk between type I and II interferon through the regulated expression of STAT1

Gough, D. J., Messina, N. L., Hii, L., Gould, J. A., Sabapathy, K., Robertson, A. P. S., Trapani, J. A., Levy, D. E., Hertzog, P. J., Clarke, C. J. P. & Johnstone, R. W., 2010, In : PLoS Biology. 8, 4 (e1000361), p. 1 - 12 12 p.

Research output: Contribution to journalArticleResearchpeer-review

6 Citations (Scopus)

Transcript profiling of Elf5+/- mammary glands during pregnancy identifies novel targets of elf5

Chehab Rogers, R., van Seuningen, I., Gould, J. A., Hertzog, P. J., Naylor, M. J. & Pritchard, M. A., 2010, In : PLoS ONE. 5, 10 (e13150), p. 1 - 10 10 p.

Research output: Contribution to journalArticleResearchpeer-review

2009
172 Citations (Scopus)

GM-CSF- and M-CSF-dependent macrophage phenotypes display differential dependence on Type I interferon signaling

Fleetwood, A. J., Dinh, H., Cook, A. D., Hertzog, P. J. & Hamilton, J. A., 2009, In : Journal of leukocyte biology. 86, 2, p. 411 - 421 11 p.

Research output: Contribution to journalArticleResearchpeer-review

158 Citations (Scopus)

INTERFEROME: the database of interferon regulated genes

Forster, S., Samarajiwa, S., Auchettl, K. & Hertzog, P., 2009, In : Nucleic Acids Research. 37, Database issue, p. D852 - D857 6 p.

Research output: Contribution to journalArticleResearchpeer-review

123 Citations (Scopus)

MyD88 adapter-like (Mal)/TIRAP interaction with TRAF6 is critical for TLR2- and TLR4-mediated NF-kappaB proinflammatory responses

Verstak, B., Nagpal, K., Bottomley, S. P., Golenbock, D. T., Hertzog, P. J. & Mansell, A. S., 2009, In : Journal of Biological Chemistry. 284, 36, p. 24192 - 24203 12 p.

Research output: Contribution to journalArticleResearchpeer-review

29 Citations (Scopus)

The genomic profile of the cerebral cortex after closed head injury in mice: Effects of minocycline

Crack, P. J., Gould, J. A., Bye, N., Ross, S., Ali, U., Habgood, M., Morganti-Kossmann, M. C., Saunders, N. R. & Hertzog, P. J., 2009, In : Journal of Neural Transmission. 116, 1, p. 1 - 12 12 p.

Research output: Contribution to journalArticleResearchpeer-review

28 Citations (Scopus)

TRIL, a functional component of the TLR4 signaling complex, highly expressed in brain

Carpenter, S., Carlson, T., Dellacasagrande, J., Garcia, A., Gibbons, S., Hertzog, P. J., Lyons, A., Lin, L., Lynch, M., Monie, T., Murphy, C., Seidl, K. J., Wells, C., Dunne, A. & O'Neill, L., 2009, In : Journal of Immunology. 183, 6, p. 3989 - 3995 7 p.

Research output: Contribution to journalArticleResearchpeer-review

54 Citations (Scopus)

Type I interferon receptor controls B-cell expression of nucleic acid-sensing Toll-like receptors and autoantibody production in a murine model of lupus

Thibault, D. L., Graham, K. L., Lee, L. Y., Balboni, I., Hertzog, P. J. & Utz, P. J., 2009, In : Arthritis Research & Therapy. 11, R112, p. 1 - 10 10 p.

Research output: Contribution to journalArticleResearchpeer-review

2008
49 Citations (Scopus)

Absence of glutathione peroxidase-1 exacerbates cerebral ischemia-reperfusion injury by reducing post-ischemic microvascular perfusion

Wong, C. H. Y., Bozinovski, S., Hertzog, P. J., Hickey, M. J. & Crack, P. J., 2008, In : Journal of Neurochemistry. 107, 1, p. 241 - 252 12 p.

Research output: Contribution to journalArticleResearchpeer-review

29 Citations (Scopus)

A conserved IFN-alpha receptor tyrosine motif directs the biological response to type I IFNs

Zhao, W., Lee, C., Piganis, R., Plumlee, C., De Weerd, N. A., Hertzog, P. J. & Schindler, C., 2008, In : Journal of Immunology. 180, 8, p. 5483 - 5489 7 p.

Research output: Contribution to journalArticleResearchpeer-review

2 Citations (Scopus)

GM-CSF-induced autoimmune gastritis in interferon alpha receptor deficient mice

Field, J., Alderuccio, F. P., Hertzog, P. J. & Toh, B-H., 2008, In : Journal of Autoimmunity. 31, 3, p. 274 - 280 7 p.

Research output: Contribution to journalArticleResearchpeer-review

43 Citations (Scopus)

Regulation of epithelium-specific Ets-like factors ESE-1 and ESE-3 in airway epithelial cells: potential roles in airway inflammation

Wu, J., Duan, R., Cao, H., Field, D., Newnham, C. M., Koehler, D. R., Zamel, N., Pritchard, M. A., Hertzog, P. J., Post, M., Tanswell, A. K. & Hu, J., 2008, In : Cell Research. 18, 6, p. 649 - 663 15 p.

Research output: Contribution to journalArticleResearchpeer-review

231 Citations (Scopus)

STAT3 and STAT1 mediate IL-11-dependent and inflammation-associated gastric tumorigenesis in gp130 receptor mutant mice

Ernst, M. R., Najdovska, M., Grail, D., Lundgren-May, T., Buchert, M., Tye, Y. M. H., Matthews, V. B., Armes, J. E., Bhathal, P. S., Hughes, N. R., Marcusson, E. G., Karras, J. G., Na, S., Sedgwick, J. D., Hertzog, P. J. & Jenkins, B. J., 2008, In : Journal of Clinical Investigation. 118, 5, p. 1727 - 1738 12 p.

Research output: Contribution to journalArticleResearchpeer-review

2007
9 Citations (Scopus)

Comparison of mice born after intracytoplasmic sperm injection with in vitro fertilization and natural mating

Wilson, T. J., Lacham, O., Gould, J. A., Holloway, A. J., Bertoncello, I., Hertzog, P. J. & Trounson, A. O., 2007, In : Molecular Reproduction and Development. 74, 1, p. 512 - 519 8 p.

Research output: Contribution to journalArticleResearchpeer-review

54 Citations (Scopus)

Macrophage lineage phenotypes and osteoclastogenesis-Complexity in the control by GM-CSF and TGF-beta

Lari, R., Fleetwood, A. J., Kitchener, P. D., Cook, A. D., Pavasovic, D., Hertzog, P. J. & Hamilton, J., 2007, In : Bone. 40, 2, p. 323 - 336 14 p.

Research output: Contribution to journalArticleResearchpeer-review

20 Citations (Scopus)

Targeting of the ETS factor Gabpalpha disrupts neuromuscular junction synaptic function

O'Leary, D. A., Noakes, P. G., Lavidis, N. A., Kola, I., Hertzog, P. J. & Ristevski, S., 2007, In : Molecular and Cellular Biology. 27, 9, p. 3470 - 3480 11 p.

Research output: Contribution to journalArticleResearchpeer-review

24 Citations (Scopus)

TGF-betaRII rescues development of small intestinal epithelial cells in Elf3-deficient mice

Flentjar, N. J., Chu, P-Y., Ng, A. Y. N., Johnstone, C. N., Heath, J. K., Ernst, M. R., Hertzog, P. J. & Pritchard, M. A., 2007, In : Gastroenterology. 132, p. 1410 - 1419 10 p.

Research output: Contribution to journalArticleResearchpeer-review

The role of type 1 interferons in TLR responses.

Noppert, S-J., Fitzgerald, K. A. & Hertzog, P. J., 2007, In : Immunology and Cell Biology. 85, p. 446 - 457 12 p.

Research output: Contribution to journalArticleOther

93 Citations (Scopus)

The role of type I interferons in TLR responses

Noppert, S-J., Fitzgerald, K. A. & Hertzog, P. J., 2007, In : Immunology and Cell Biology. 85, p. 446 - 457 12 p.

Research output: Contribution to journalArticleResearchpeer-review

45 Citations (Scopus)

Toll-like receptor signalling and the clinical benefits that lie within

Verstak, B., Hertzog, P. J. & Mansell, A. S., 2007, In : Inflammation Research. 56, 1, p. 1 - 10 10 p.

Research output: Contribution to journalArticleResearchpeer-review

Type 1 interferon receptors: Biochemistry and biological functions.

De Weerd, N. A., Samarajiwa, S. & Hertzog, P. J., 2007, In : Journal of Biological Chemistry. 282, 28, p. 20053 - 20057 5 p.

Research output: Contribution to journalArticleOther

163 Citations (Scopus)

Type I IFN contributes to NK cell homeostasis, activation, and antitumor function

Swann, J. B., Hayakawa, Y., Zerafa, N., Sheehan, K. CF., Scott, B. M., Schreiber, R. D., Hertzog, P. J. & Smyth, M. J., 2007, In : Journal of Immunology. 178, 12, p. 7540 - 7549 10 p.

Research output: Contribution to journalArticleResearchpeer-review

2006
151 Citations (Scopus)

Blocking monoclonal antibodies specific for mouse IFN-alpha/beta receptor subunit 1 (IFNAR-1) from mice immunized by in vivo hydrodynamic transfection

Sheehan, K. CF., Lai, K. S., Dunn, G. P., Bruce, A. T., Diamond, M. S., Heutel, J. D., Dungo-Arthur, C., Carrero, J. A., White, J. M., Hertzog, P. J. & Schreiber, R. D., 2006, In : Journal of Interferon and Cytokine Research. 26, p. 804 - 819 16 p.

Research output: Contribution to journalArticleResearchpeer-review

48 Citations (Scopus)

Lack of glutathione peroxidase-1 exacerbates Abeta-mediated neurotoxicity in cortical neurons

Crack, P. J., Cimdins, K., Ali, U., Hertzog, P. J. & Iannello, R. C., 2006, In : Journal of Neural Transmission. 113, p. 645 - 657 13 p.

Research output: Contribution to journalArticleResearchpeer-review

61 Citations (Scopus)

Potential contribution of NF-kappaB in neuronal cell death in the glutathione peroxidase-1 knockout mouse in response to ischemia-reperfusion injury

Crack, P. J., Taylor, J. M., Ali, U., Mansell, A. S. & Hertzog, P. J., 2006, In : Stroke. 37, 6, p. 1533 - 1538 6 p.

Research output: Contribution to journalArticleResearchpeer-review

389 Citations (Scopus)

Suppressor of cytokine signaling 1 negatively regulates Toll-like receptor signaling by mediating Mal degradation

Mansell, A. S., Smith, R. A., Doyle, S. L., Gray, P., Fenner, J. E., Crack, P. J., Nicholson, S. E., Hilton, D. J., O'Neill, L. & Hertzog, P. J., 2006, In : Nature Immunology. 7, 2, p. 148 - 155 8 p.

Research output: Contribution to journalArticleResearchpeer-review

191 Citations (Scopus)

Suppressor of cytokine signaling 1 regulates the immune response to infection by a unique inhibition of type I interferon activity

Fenner, J. E., Starr, R. J., Cornish, A. L., Zhang, J-G., Metcalf, D., Schreiber, R. D., Sheehan, K., Hilton, D. J., Alexander, W. S. & Hertzog, P. J., 2006, In : Nature Immunology. 7, 1, p. 33 - 39 7 p.

Research output: Contribution to journalArticleResearchpeer-review

2005
15 Citations (Scopus)

Constitutive activation of gp130 leads to neuroendocrine differentiation in vitro and in vivo

Palmer, J., Ernst, M. R., Hammacher, A. & Hertzog, P. J., 2005, In : Prostate. 62, 3, p. 282 - 289 8 p.

Research output: Contribution to journalArticleResearchpeer-review

44 Citations (Scopus)

Diminished Akt phosphorylation in neurons lacking glutathione peroxidase-1 (Gpx1) leads to increased susceptibility to oxidative stress-induced cell death

Taylor, J. M., Ali, U., Iannello, R. C., Hertzog, P. J. & Crack, P. J., 2005, In : Journal of Neurochemistry. 92, p. 283 - 293 11 p.

Research output: Contribution to journalArticleResearchpeer-review

90 Citations (Scopus)

Elf5 is essential for early embryogenesis and mammary gland development during pregnancy and lactation

Zhou, J., Chehab, R., Tkalcevic, J., Naylor, M. J., Harris, J., Wilson, T. J., Tsao, S. E., Tellis, I., Zavarsek, S., Xu, D., Lapinskas, E. J., Visvader, J., Lindeman, G. J., Thomas, R. S., Ormandy, C. J., Hertzog, P. J., Kola, I. & Pritchard, M. A., 2005, In : EMBO Journal. 24, 3, p. 635 - 644 10 p.

Research output: Contribution to journalArticleResearchpeer-review

10 Citations (Scopus)

Identification and expression analysis of alternative transcripts of the mouse GA-binding protein (Gabp) subunits alpha and beta1

O'leary, D. A., Koleski, D., Kola, I., Hertzog, P. J. & Ristevski, S., 2005, In : Gene. 344, p. 79 - 92 14 p.

Research output: Contribution to journalArticleResearchpeer-review

46 Citations (Scopus)

Kidney expression of glutathione peroxidase-1 is not protective against streptozotocin-induced diabetic nephropathy

De Haan-Klein, J. B., Stefanovic, N., Nikolic-Paterson, D. J., Scurr, L. L., Croft, K. D., Mori, T. A., Hertzog, P. J., Kola, I., Atkins, R. C. & Tesch, G. H., 2005, In : American Journal of Physiology - Renal Physiology. 289, 3, p. F544 - F551 8 p.

Research output: Contribution to journalArticleResearchpeer-review

23 Citations (Scopus)

Neonatal calyceal dilation and renal fibrosis resulting from loss of Adamts-1 in mouse kidney is due to a developmental dysgenesis

Mittaz, L., Ricardo, S. D., Martinez, G., Kola, I., Kelly, D. J., Little, M. H., Hertzog, P. J. & Pritchard, M. A., 2005, In : Nephrology Dialysis Transplantation. 20, p. 419 - 423 5 p.

Research output: Contribution to journalArticleResearchpeer-review

2004
126 Citations (Scopus)

Adamts-1 is essential for the development and function of the urogenital system

Mittaz, L., Russell, D. L., Wilson, T. J., Brasted, M., Tkalcevic, J., Salamonsen, L. A., Hertzog, P. J. & Pritchard, M. A., 2004, In : Biology of Reproduction. 70, 4, p. 1096 - 1105 10 p.

Research output: Contribution to journalArticleResearchpeer-review