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Research Output 1975 2019

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18 Citations (Scopus)

Aberrant Activation of JAK/STAT Pathway Components in Response to G-CSF, Interferon-a/p and Interferon-y in NFS-60 Cells

Novak, U., Ward, A. C., Hertzog, P. J., Hamilton, J. A. & Paradiso, L., 1 Jan 1996, In : Growth Factors. 13, 42067, p. 251-260 10 p.

Research output: Contribution to journalArticleResearchpeer-review

12 Citations (Scopus)

Aberrant expression of intestinal mucin antigens associated with colorectal carcinoma defined by a panel of monoclonal antibodies

Hertzog, P. J., Pilbrow, S. J., Pedersen, J., Polglase, A. L., Lawson, M. & Linnane, A. W., 1 Jan 1991, In : British Journal of Cancer. 64, 5, p. 779-808 30 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
49 Citations (Scopus)

Absence of glutathione peroxidase-1 exacerbates cerebral ischemia-reperfusion injury by reducing post-ischemic microvascular perfusion

Wong, C. H. Y., Bozinovski, S., Hertzog, P. J., Hickey, M. J. & Crack, P. J., 2008, In : Journal of Neurochemistry. 107, 1, p. 241 - 252 12 p.

Research output: Contribution to journalArticleResearchpeer-review

1 Citation (Scopus)

A cell type-specific transcriptomic approach to map B cell and monocyte type I interferon-linked pathogenic signatures in Multiple Sclerosis

Severa, M., Rizzo, F., Srinivasan, S., Di Dario, M., Giacomini, E., Buscarinu, M. C., Cruciani, M., Etna, M. P., Sandini, S., Mechelli, R., Farina, A., Trivedi, P., Hertzog, P. J., Salvetti, M., Farina, C. & Coccia, E. M., 1 Jul 2019, In : Journal of Autoimmunity. 101, p. 1-16 16 p.

Research output: Contribution to journalArticleResearchpeer-review

29 Citations (Scopus)

A conserved IFN-alpha receptor tyrosine motif directs the biological response to type I IFNs

Zhao, W., Lee, C., Piganis, R., Plumlee, C., De Weerd, N. A., Hertzog, P. J. & Schindler, C., 2008, In : Journal of Immunology. 180, 8, p. 5483 - 5489 7 p.

Research output: Contribution to journalArticleResearchpeer-review

126 Citations (Scopus)

Adamts-1 is essential for the development and function of the urogenital system

Mittaz, L., Russell, D. L., Wilson, T. J., Brasted, M., Tkalcevic, J., Salamonsen, L. A., Hertzog, P. J. & Pritchard, M. A., 2004, In : Biology of Reproduction. 70, 4, p. 1096 - 1105 10 p.

Research output: Contribution to journalArticleResearchpeer-review

59 Citations (Scopus)

Administration of Imiquimod, an Interferon Inducer, in Asymptomatic Human Immunodeficiency Virus - Infected Persons to Determine Safety and Biologic Response Modification

Goldstein, D., Hertzog, P. J., Tomkinson, E., Couldwell, D., McCarville, S., Parrish, S., Cunningham, P., Newell, M., Owens, M. & Cooper, D. A., 1998, In : Journal of Infectious Diseases. p. 858 - 861 4 p.

Research output: Contribution to journalArticleResearchpeer-review

31 Citations (Scopus)

A gene on human chromosome 21 located in the region 21q22.2 to 21q22.3 encodes a factor necessary for signal transduction and antiviral response to type I interferons

Hertzog, P. J., Hwang, S. Y., Holland, K. A., Tymms, M. J., Iannello, R. & Kola, I., 13 May 1994, In : Journal of Biological Chemistry. 269, 19, p. 14088-14093 6 p.

Research output: Contribution to journalArticleResearchpeer-review

59 Citations (Scopus)

A high pressure liquid chromatography study on the removal of DNA-bound aflatoxin B1 in rat liver and in vitro

Hertzog, P. J., Smith, J. R. L. & Garner, R. C., 1 Sep 1980, In : Carcinogenesis. 1, 9, p. 787-793 7 p.

Research output: Contribution to journalArticleResearchpeer-review

9 Citations (Scopus)

A hot spot on interferon α/β receptor subunit 1 (IFNAR1) underpins its interaction with interferon-β and dictates signaling

de Weerd, N. A., Matthews, A. Y., Pattie, P. R., Bourke, N. M., Lim, S. S., Vivian, J. P., Rossjohn, J. & Hertzog, P. J., 5 May 2017, In : Journal of Biological Chemistry. 292, 18, p. 7554-7565 13 p.

Research output: Contribution to journalArticleResearchpeer-review

3 Citations (Scopus)

A Human CD2 minigene directs CRE-mediated recombination in T cells in vivo

Wilson, T. J., Cowdery, H. E., Xu, D., Kola, I. & Hertzog, P. J., 2002, In : Genesis. 33, 4, p. 181 - 184 4 p.

Research output: Contribution to journalArticleResearchpeer-review

Akt phosphorylation and NFactivation are counterregulated under conditions of oxidative stress

Taylor, J. M., Crack, P. J., Gould, J. A., Ali, U., Hertzog, P. J. & Iannello, R. C., 2004, In : Experimental Cell Research. 300, p. 463 - 475 13 p.

Research output: Contribution to journalArticleResearchpeer-review

20 Citations (Scopus)

Akt phosphorylation and NFκB activation are counterregulated under conditions of oxidative stress

Taylor, J. M., Crack, P. J., Gould, J. A., Ali, U., Hertzog, P. J. & Iannello, R. C., 1 Nov 2004, In : Experimental Cell Research. 300, 2, p. 463-475 13 p.

Research output: Contribution to journalArticleResearchpeer-review

30 Citations (Scopus)

A major site of expression of the ets transcription factor Elf5 is epithelia of exocrine glands

Lapinskas, E. J., Palmer, J., Ricardo, S. D., Hertzog, P. J., Hammacher, A. & Pritchard, M. A., 2004, In : Histochemistry and Cell Biology. 122, 6, p. 521 - 526 6 p.

Research output: Contribution to journalArticleResearchpeer-review

244 Citations (Scopus)

Analysis of microRNA turnover in mammalian cells following Dicer1 ablation

Gantier, M., McCoy, C., Rusinova, I., Saulep, D., Wang, D., Xu, D., Irving, A., Behlke, M., Hertzog, P., Mackay-Fisson, F. & Williams, B., 2011, In : Nucleic Acids Research. 39, 13, p. 5692 - 5703 12 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access

An imbalance in antioxidant defense affects cellular function: The pathophysiological consequences of a reduction in antioxidant defense in the glutathione peroxidase-1 (Gpx1) knockout mouse

De Haan, J. B., Crack, P. J., Flentjar, N. J., Iannello, R. C., Hertzog, P. J. & Kola, I., 2003, In : Redox Report. 8, 2, p. 69 - 79 11 p.

Research output: Contribution to journalArticleResearchpeer-review

A novel member of the STOMATIN/EPB72/mec-2 family, stomatin-like2 (STOML2), is ubiquitously expressed and localizes to HSA chromosome 9p13.1

Owczarek, C. M., Treutlein, H. R., Portbury, K. J., Gulluyan, L. M., Kola, I. & Hertzog, P. J., 2001, In : Cytogenetics and Cell Genetics. 92, p. 196 - 203 8 p.

Research output: Contribution to journalArticleResearchpeer-review

24 Citations (Scopus)

A novel member of the STOMATIN/EPB72/mec-2 family, stomatin-like 2 (STOML2), is ubiquitously expressed and localizes to HSA chromosome 9p13.1

Owczarek, C. M., Treutlein, H. R., Portbury, K. J., Gulluyan, L. M., Kola, I. & Hertzog, P. J., 24 Jul 2001, In : Cytogenetics and Cell Genetics. 92, 3-4, p. 196-203 8 p.

Research output: Contribution to journalArticleResearchpeer-review

127 Citations (Scopus)

Antiproliferative potencies of interferons on melanoma cell lines and xenografts: Higher efficacy of interferon β

Johns, T. G., Mackay, I. R., Callister, K. A., Hertzog, P. J., Devenish, R. J. & Linnance, A. W., 5 Aug 1992, In : Journal of the National Cancer Institute. 84, 15, p. 1185-1190 6 p.

Research output: Contribution to journalArticleResearchpeer-review

26 Citations (Scopus)

Antiviral and Antiproliferative Activities of Interferon-α1: The Role of Cysteine Residues

Beilharz, M. W., Nisbet, I. T., Tymms, M. J., Hertzog, P. J. & Linnane, A. W., 1 Jan 1986, In : Journal of Interferon Research. 6, 6, p. 677-685 9 p.

Research output: Contribution to journalArticleResearchpeer-review

291 Citations (Scopus)

A null mutation in the gene encoding a type I interferon receptor component eliminates antiproliferative and antiviral responses to interferons α and β and alters macrophage responses

Hwang, S. Y., Hertzog, P. J., Holland, K. A., Sumarsono, S. H., Tymms, M. J., Hamilton, J. A., Whitty, G., Bertoncello, I. & Kola, I., 21 Nov 1995, In : Proceedings of the National Academy of Sciences of the United States of America. 92, 24, p. 11284-11288 5 p.

Research output: Contribution to journalArticleResearchpeer-review

11 Citations (Scopus)

A proline deletion in IFNAR1 impairs IFN-signaling and underlies increased resistance to tuberculosis in humans

Zhang, G., Deweerd, N. A., Stifter, S. A., Liu, L., Zhou, B., Wang, W., Zhou, Y., Ying, B., Hu, X., Matthews, A. Y., Ellis, M., Triccas, J. A., Hertzog, P. J., Britton, W. J., Chen, X. & Feng, C. G., 1 Dec 2018, In : Nature Communications. 9, 1, 9 p., 85.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
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1 Citation (Scopus)

Assignment of protein kinase C mu (PRKCM) to human chromosome band 14q11 with somatic cell hybrids and radiation hybrids

Owczarek, C. M., Portbury, K. J., Kola, I. & Hertzog, P. J., 2000, In : Cytogenetics and Cell Genetics. p. 240 - 241 2 p.

Research output: Contribution to journalArticleResearchpeer-review

1 Citation (Scopus)

A structural "star" in interferon gamma signaling

Hertzog, P. J. & de Weerd, N. A., 1 May 2019, In : Immunology and Cell Biology. 97, 5, p. 442-444 3 p.

Research output: Contribution to journalArticleOtherpeer-review

Open Access
26 Citations (Scopus)

A subset of HLA-I peptides are not genomically templated: Evidence for cis- and trans-spliced peptide ligands

Faridi, P., Li, C., Ramarathinam, S. H., Vivian, J. P., Illing, P. T., Mifsud, N. A., Ayala, R., Song, J., Gearing, L. J., Hertzog, P. J., Ternette, N., Rossjohn, J., Croft, N. P. & Purcell, A. W., 12 Oct 2018, In : Science Immunology. 3, 28, 12 p., eaar3947.

Research output: Contribution to journalArticleResearchpeer-review

14 Citations (Scopus)

A type I interferon signaling factor, ISF21, encoded on chromosome 21 is distinct from receptor components and their down-regulation and is necessary for transcriptional activation of interferon-regulated genes

Holland, K. A., Owczarek, C. M., Hwang, S. Y., Tymms, M. J., Constantinescu, S. N., Pfeffer, L. M., Kola, I. & Hertzog, P. J., 22 Aug 1997, In : Journal of Biological Chemistry. 272, 34, p. 21045-21051 7 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access

A type I interferon signaling factor, ISF21, encoded on chromosome 21 is distinct from receptor components and their down-regulation and is necessary for transcritpional activation of interferon-regulated genes

Holland, K. A., Owczarek, C. M., Hwang, S. Y., Tymms, M. J., Constantinescu, S., Pfeffer, L. M., Kola, I. & Hertzog, P. J., 1997, In : Journal of Biological Chemistry. p. 21045 - 21051 7 p.

Research output: Contribution to journalArticleResearchpeer-review

186 Citations (Scopus)

Bacterial membrane vesicles deliver peptidoglycan to NOD1 in epithelial cells

Liaskos, M., Turnbull, L., Carneiro, L., Firth, S. D., Coleman, H. A., Parkington, H. C., Le Bourhis, L., Karrar, A., Viala, J., Mak, J., Hutton, M. L., Davies, J. K., Crack, P. J., Hertzog, P. J., Philpott, D., Girardin, S. E., Whitchurch, C. B. & Ferrero, R. L., 2010, In : Cellular Microbiology. 12, p. 372 - 385 13 p.

Research output: Contribution to journalArticleResearchpeer-review

9 Citations (Scopus)

Binding of interferon-α and -β to a component of the human type I interferon receptor expressed in simian cells

Hwang, S. Y., Holland, K. A., Kola, I. & Hertzog, P. J., 1 Jan 1996, In : International Journal of Biochemistry and Cell Biology. 28, 8, p. 911-916 6 p.

Research output: Contribution to journalArticleResearchpeer-review

42 Citations (Scopus)

Biological and chemical studies on 8,9-dihydroxy-8,9-dihydro-aflatoxin B1 and some of its esters

Coles, B. F., Welch, A. M., Hertzog, P. J., Smith, J. R. L. & Garner, R. C., 1 Jan 1980, In : Carcinogenesis. 1, 1, p. 79-90 12 p.

Research output: Contribution to journalArticleResearchpeer-review

Blocking HIV-1 transmission in the female reproductive tract: from microbicide development to exploring local antiviral responses

Eid, S. G., Mangan, N., Hertzog, P. J. & Mak, J., 2015, In : Clinical and Translational Immunology. 4, 10, 9 p., e43.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
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150 Citations (Scopus)

Blocking monoclonal antibodies specific for mouse IFN-alpha/beta receptor subunit 1 (IFNAR-1) from mice immunized by in vivo hydrodynamic transfection

Sheehan, K. CF., Lai, K. S., Dunn, G. P., Bruce, A. T., Diamond, M. S., Heutel, J. D., Dungo-Arthur, C., Carrero, J. A., White, J. M., Hertzog, P. J. & Schreiber, R. D., 2006, In : Journal of Interferon and Cytokine Research. 26, p. 804 - 819 16 p.

Research output: Contribution to journalArticleResearchpeer-review

Bone disease - Current knowledge and future propects

Lazner, F., Wolvetang, E. J., Lazner, D. & Hertzog, P. J., 2001, In : Current Genomics. 2, 2, p. 91 - 124 34 p.

Research output: Contribution to journalArticleResearchpeer-review

Bone disease - Current knowledge and future prospects

Lazner, F., Wolvetang, E., Lazner, D. & Hertzog, P., 5 Jun 2001, In : Current Genomics. 2, 2, p. 91-124 34 p.

Research output: Contribution to journalArticleResearchpeer-review

381 Citations (Scopus)

Cathepsin K knockout mice develop osteopetrosis due to a deficit in matrix degradation but not demineralization

Gowen, M., Lazner, F., Dodds, R., Kapadia, R., Feild, J., Tavaria, M., Bertoncello, I., Drake, F., Zavarsek, S., Tellis, I., Hertzog, P. J., Debouck, C. & Kola, I., 1999, In : Journal of Bone and Mineral Research. p. 1654 - 1663 10 p.

Research output: Contribution to journalArticleResearchpeer-review

42 Citations (Scopus)

Cellular localization of α‐interferon in hepatitis B virus‐infected liver tissue

Jilbert, A. R., Burrell, C. J., Gowans, E. J., Hertzog, P. J., Linnane, A. W. & Marmion, B. P., 1 Jan 1986, In : Hepatology. 6, 5, p. 957-961 5 p.

Research output: Contribution to journalArticleResearchpeer-review

59 Citations (Scopus)

Characterisation of the imidazole ring-opened forms of trans-8,9-di-hydro-8-(7-guanyl)9-hydroxy aflatoxin b1

Hertzog, P. J., Smith, J. R. L. & Garner, R. C., 1 Dec 1982, In : Carcinogenesis. 3, 6, p. 723-725 3 p.

Research output: Contribution to journalArticleResearchpeer-review

12 Citations (Scopus)

Characterization and transcriptional analysis of the mouse chromosome 16 cytokine receptor gene cluster

Hardy, M. P., Sanij, E., Hertzog, P. J. & Owczarek, C. M., 1 Feb 2003, In : Mammalian Genome. 14, 2, p. 105-118 14 p.

Research output: Contribution to journalArticleResearchpeer-review

3 Citations (Scopus)

Characterization of epitopes of the yeast mitochondrial H+-ATPase complex recognized by monoclonal antibodies

Hadikusumo, R. G., Hertzog, P. J. & Marzuki, S., 10 Jun 1986, In : BBA - Bioenergetics. 850, 1, p. 33-40 8 p.

Research output: Contribution to journalArticleResearchpeer-review

3 Citations (Scopus)

Characterization of interferons produced by peripheral blood mononuclear cells from healthy subjects in response to Corynebacterium parvum or poly I: poly C

Hertzog, P. J., Cheetham, B. F., Sexton, J. L. & Linnane, A. W., 1 Dec 1989, In : Biochemistry International. 19, 6, p. 1427-1436 10 p.

Research output: Contribution to journalArticleResearchpeer-review

1 Citation (Scopus)

Characterization of monoclonal antibodies specific to the transcription factor ETS-2 protein

Sanij, E., Scott, B. M., Wilson, T. J., Xu, D., Hertzog, P. J. & Wolvetang, E. J., 2003, In : Immunology Letters. 86, 1, p. 63 - 70 8 p.

Research output: Contribution to journalArticleResearchpeer-review

134 Citations (Scopus)

Characterization of the type I interferon locus and identification of novel genes

Hardy, M., Owczarek, C. M., Jermiin, L. S., Ejdeback, M. & Hertzog, P. J., 2004, In : Genomics. 84, 2, p. 331 - 345 15 p.

Research output: Contribution to journalArticleResearchpeer-review

9 Citations (Scopus)

Chemokine receptor CCR5 is not required for development of experimental autoimmune gastritis

Field, J., Marshall, A. C. J., Hertzog, P. J., Wells, T. N., Alderuccio, F. P. & Toh, B-H., 2003, In : Clinical Immunology. 109, 2, p. 238 - 247 10 p.

Research output: Contribution to journalArticleResearchpeer-review

Cloning and characterisation of a novel component of the murine type I interferon receptor, IFNAR2

Hwang, S. Y., Owczarek, C. M., Holland, K. A., Weaver, B., Reich, N. C., Kola, I., Gulluyan, L. & Hertzog, P. J., 1997, In : Journal of Biological Chemistry. p. 23865 - 23870 6 p.

Research output: Contribution to journalArticleResearchpeer-review

46 Citations (Scopus)

Cloning and characterization of soluble and transmembrane isoforms of a novel component of the murine type I interferon receptor, IFNAR 2

Owczarek, C. M., Hwang, S. Y., Holland, K. A., Gulluyan, L. M., Tavaria, M., Weaver, B., Reich, N. C., Kola, I. & Hertzog, P. J., 19 Sep 1997, In : Journal of Biological Chemistry. 272, 38, p. 23865-23870 6 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
9 Citations (Scopus)

Comparative antiproliferative and receptor binding activities of interferons α and β on lymphoblastoid and melanoma cells

Hertzog, P. J., Johns, T. G., Callister, K. A., Dinatale, A. & Linnane, A. W., 1 Dec 1990, In : Biochemistry International. 22, 6, p. 1095-1102 8 p.

Research output: Contribution to journalArticleResearchpeer-review

4 Citations (Scopus)

Comparative metabolomics and transcriptomics reveal multiple pathways associated with polymyxin killing in pseudomonas aeruginosa

Han, M-L., Zhu, Y., Creek, D. J., Lin, Y-W., Gutu, A. D., Hertzog, P., Purcell, T., Shen, H-H., Moskowitz, S. M., Velkov, T. & Li, J., 1 Jan 2019, In : mSystems. 4, 1, 18 p., e00149-18.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
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13 Citations (Scopus)

Comparison of different ELISAs for the detection of monoclonal antibodies to human interferon-α. Implications for antibody screening

Overall, M. L., Marzuki, S. & Hertzog, P. J., 21 Apr 1989, In : Journal of Immunological Methods. 119, 1, p. 27-33 7 p.

Research output: Contribution to journalArticleResearchpeer-review

9 Citations (Scopus)

Comparison of mice born after intracytoplasmic sperm injection with in vitro fertilization and natural mating

Wilson, T. J., Lacham, O., Gould, J. A., Holloway, A. J., Bertoncello, I., Hertzog, P. J. & Trounson, A. O., 2007, In : Molecular Reproduction and Development. 74, 1, p. 512 - 519 8 p.

Research output: Contribution to journalArticleResearchpeer-review

Comparison of the effects of Enovid and α-naphthylisothiocyanate on bromosulphophthalein excretion in Syrian golden hamsters

Hertzog, P. J., Ilacqua, V. & Gingell, R., 15 Mar 1980, In : Biochemical Pharmacology. 29, 6, p. 960-962 3 p.

Research output: Contribution to journalArticleResearchpeer-review