20002020

Research output per year

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Research Output

2020

CDK13 cooperates with CDK12 to control global RNA polymerase II processivity

Fan, Z., Devlin, J. R., Hogg, S. J., Doyle, M. A., Harrison, P. F., Todorovski, I., Cluse, L. A., Knight, D. A., Sandow, J. J., Gregory, G., Fox, A., Beilharz, T. H., Kwiatkowski, N., Scott, N. E., Vidakovic, A. T., Kelly, G. P., Svejstrup, J. Q., Geyer, M., Gray, N. S., Vervoort, S. J. & 1 others, Johnstone, R. W., 29 Apr 2020, In : Science Advances. 6, 18, 18 p., eaaz5041.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
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FGF13 promotes metastasis of triple-negative breast cancer

Johnstone, C. N., Pattison, A. D., Harrison, P. F., Powell, D. R., Lock, P., Ernst, M., Anderson, R. L. & Beilharz, T. H., 1 Jul 2020, In : International Journal of Cancer. 147, 1, p. 230-243 14 p.

Research output: Contribution to journalArticleResearchpeer-review

Splice-site strength estimation: A simple yet powerful approach to analyse RNA splicing

Dent, C., Singh, S., Mishra, S., Shamaya, N., Loo, K. P., Sarwade, R. D., Harrison, P., Sureshkumar, S., Powell, D. & Balasubramanian, S., Feb 2020, 49 p. bioRxiv.

Research output: Other contributionResearch

Open Access
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The YEATS Domain Histone Crotonylation Readers Control Virulence-Related Biology of a Major Human Pathogen

Wang, Q., Verma, J., Vidan, N., Wang, Y., Tucey, T. M., Lo, T. L., Harrison, P. F., See, M., Swaminathan, A., Kuchler, K., Tscherner, M., Song, J., Powell, D. R., Sopta, M., Beilharz, T. H. & Traven, A., 21 Apr 2020, In : Cell Reports. 31, 3, 16 p., 107528.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
File
2019

PAT-Seq: A Method for Simultaneous Quantitation of Gene Expression, Poly(A)-Site Selection and Poly(A)-Length Distribution in Yeast Transcriptomes

Swaminathan, A., Harrison, P. F., Preiss, T. & Beilharz, T. H., 2019, Yeast Systems Biology: Methods and Protocols. Oliver, S. G. & Castrillo, J. I. (eds.). 2nd ed. New York, NY: Humana Press, p. 141-164 24 p. (Methods in Molecular Biology; vol. 2049).

Research output: Chapter in Book/Report/Conference proceedingChapter (Book)Otherpeer-review

1 Citation (Scopus)

Topconfects: A package for confident effect sizes in differential expression analysis provides a more biologically useful ranked gene list

Harrison, P. F., Pattison, A. D., Powell, D. R. & Beilharz, T. H., 28 Mar 2019, In : Genome Biology. 20, 1, 12 p., 67.

Research output: Contribution to journalArticleOtherpeer-review

Open Access
File
1 Citation (Scopus)
2018

Concurrent host-pathogen transcriptional responses in a clostridium perfringens murine myonecrosis infection

Low, L-Y., Harrison, P. F., Gould, J., Powell, D. R., Choo, J. M., Forster, S. C., Chapman, R., Gearing, L. J., Cheung, J. K., Hertzog, P. & Rood, J. I., 1 Mar 2018, In : mBio. 9, 2, 15 p., e00473-18.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
File
10 Citations (Scopus)

Functional and genomic characterisation of a xenograft model system for the study of metastasis in triple-negative breast cancer

Johnstone, C. N., Pattison, A. D., Gorringe, K. L., Harrison, P. F., Powell, D. R., Lock, P., Baloyan, D., Ernst, M., Stewart, A. G., Beilharz, T. H. & Anderson, R. L., 29 May 2018, In : Disease Models and Mechanisms. 11, 5, 14 p., 032250.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
File
5 Citations (Scopus)

Glucose Homeostasis Is Important for Immune Cell Viability during Candida Challenge and Host Survival of Systemic Fungal Infection

Tucey, T. M., Verma, J., Harrison, P. F., Snelgrove, S. L., Lo, T. L., Scherer, A. K., Barugahare, A. A., Powell, D. R., Wheeler, R. T., Hickey, M. J., Beilharz, T. H., Naderer, T. & Traven, A., 1 May 2018, In : Cell Metabolism. 27, 5, p. 988-1006.e7 27 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
File
37 Citations (Scopus)

αβ T-cell receptors with a central CDR3 cysteine are enriched in CD8αα intraepithelial lymphocytes and their thymic precursors

Wirasinha, R. C., Singh, M., Archer, S. K., Chan, A., Harrison, P. F., Goodnow, C. C. & Daley, S. R., Jul 2018, In : Immunology and Cell Biology. 96, 6, p. 553-561 9 p.

Research output: Contribution to journalArticleResearchpeer-review

7 Citations (Scopus)
2017

Coordination of cell cycle progression and mitotic spindle assembly involves histone H3 lysine 4 methylation by set1/COMPASS

Beilharz, T. H., Harrison, P. F., Miles, D. M., See, M. M., Le, U. M. M., Kalanon, M., Curtis, M. J., Hasan, Q., Saksouk, J., Margaritis, T., Holstege, F., Geli, V. & Dichtl, B., 1 Jan 2017, In : Genetics. 205, 1, p. 185-199 15 p.

Research output: Contribution to journalArticleResearchpeer-review

4 Citations (Scopus)

PiRNAs and Aubergine cooperate with Wispy poly(A) polymerase to stabilize mRNAs in the germ plasm

Dufourt, J., Bontonou, G., Chartier, A., Jahan, C., Meunier, A. C., Pierson, S., Harrison, P. F., Papin, C., Beilharz, T. H. & Simonelig, M., 1 Dec 2017, In : Nature Communications. 8, 1, 12 p., 1305.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
File
14 Citations (Scopus)
2016

Perturbation of the two-component signal transduction system, BprRS, results in attenuated virulence and motility defects in Burkholderia pseudomallei

Lazar Adler, N. R., Allwood, E. M., Deveson Lucas, D., Harrison, P., Watts, S., Dimitropoulos, A., Treerat, P., Alwis, P., Devenish, R. J., Prescott, M., Govan, B., Adler, B., Harper, M. & Boyce, J. D., 4 May 2016, In : BMC Genomics. 17, 17 p., 331.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
File
8 Citations (Scopus)

RNA-seq analysis of virR and revR mutants of Clostridium perfringens

Low, L-Y., Harrison, P. F., Lin, Y-H., Boyce, J. D., Rood, J. I. & Cheung, J. K., 23 May 2016, In : BMC Genomics. 17, 14 p., 391.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
File
6 Citations (Scopus)
2015

Integration of posttranscriptional gene networks into metabolic adaptation and biofilm maturation in candida albicans

Verma-Gaur, J., Qu, Y., Harrison, P. F., Lo, T. L., Quenault, T. L., Dagley, M. J., Belousoff, M. J., Powell, D. R., Beilharz, T. H. & Traven, A., 2015, In : PLoS Genetics. 11, 10, 28 p., e1005590.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
File
22 Citations (Scopus)

PAT-seq: a method to study the integration of 3'-UTR dynamics with gene expression in the eukaryotic transcriptome

Harrison, P. F., Powell, D. R., Clancy, J. L., Preiss, T., Boag, P. R., Traven, A., Seemann, T. & Beilharz, T. H., 2015, In : Rna-A Publication of the Rna Society. 21, 8, p. 1502 - 1510 9 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
File
34 Citations (Scopus)

POS-1 promotes endo-mesoderm development by inhibiting the cytoplasmic polyadenylation of neg-1 mRNA

Elewa, A., Shirayama, M., Kaymak, E., Harrison, P. F., Powell, D. R., Du, Z., Chute, C. D., Woolf, H., Yi, D., Ishidate, T., Srinivasan, J., Bao, Z., Beilharz, T. H., Ryder, S. P. & Mello, C. C., 2015, In : Developmental Cell. 34, 1, p. 108 - 118 11 p.

Research output: Contribution to journalArticleResearchpeer-review

5 Citations (Scopus)

The transcriptomic response of Acinetobacter baumannii to colistin and doripenem alone and in combination in an in vitro pharmacokinetics/pharmacodynamics model

Henry, R. M., Crane, B. A., Powell, D. R., Deveson-Lucas, D. S., Li, Z., Aranda, J., Harrison, P. F., Nation, R. L., Adler, B., Harper, M., Boyce, J. D. & Li, J., 2015, In : Journal of Antimicrobial Chemotherapy. 70, 5, p. 1303 - 1313 11 p.

Research output: Contribution to journalArticleResearchpeer-review

35 Citations (Scopus)
2014

Adaptive change inferred from genomic population analysis of the ST93 epidemic clone of community-associated methicillin-resistant Staphylococcus aureus

Stinear, T. P., Holt, K. E., Chua, K., Stepnell, J., Tuck, K. L., Coombs, G., Harrison, P. F., Seemann, T. & Howden, B. P., 2014, In : Genome Biology and Evolution. 6, 2, p. 366 - 378 13 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
18 Citations (Scopus)

Innate immune pathways in afferent lymph following vaccination with poly(I:C)-containing liposomes

Burke, M. L., de Veer, M. J., Pleasance, J. L., Neeland, M., Elhay, M. J., Harrison, P. F. & Meeusen, E. N. T., 2014, In : Innate Immunity. 20, 5, p. 501 - 510 10 p.

Research output: Contribution to journalArticleResearchpeer-review

11 Citations (Scopus)

The use of high-throughput DNA sequencing in the investigation of antigenic variation: application to Neisseria species

Davies, J. K., Harrison, P. F., Lin, Y-H., Bartley, S. N., Khoo, C. A., Seemann, T., Ryan, C. S., Kahler, C. M. & Hill, S. A., 2014, In : PLoS ONE. 9, 1, 9 p., e86704.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
File
9 Citations (Scopus)
2013

Analysis of the small RNA transcriptional response in multidrug-resistant Staphylococcus aureus after antimicrobial exposure

Howden, B. P., Beaume, M., Harrison, P. F., Hernandez, D., Schrenzel, J., Seemann, T., Francois, P. & Stinear, T. P., 2013, In : Antimicrobial Agents and Chemotherapy. 57, 8, p. 3864 - 3874 11 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
44 Citations (Scopus)

Regulation of sialidase production in Clostridium perfringens by the orphan sensor histidine kinase ReeS

Hiscox, T. J., Harrison, P. F., Chakravorty, A., Choo, J. M. F., Ohtani, K., Shimizu, T., Cheung, K-L. J. & Rood, J. I., 2013, In : PLoS ONE. 8, 9, 8 p., e73525.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
File
12 Citations (Scopus)

Transcriptional profiling of a yeast colony provides new insight into the heterogeneity of multicellular fungal communities

Traven, A., Jaenicke, A., Harrison, P., Swaminathan, A., Seemann, T. & Beilharz, T. H., 2012, In : PLoS ONE. 7, 9, 11 p., e46243.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
File
24 Citations (Scopus)
2011

Evolution of multidrug resistance during Staphylococcus aureus infection involves mutation of the essential two component regulator walKR

Howden, B. P., McEvoy, C. RE., Allen, D. L., Chua, K., Gao, W., Harrison, P. F., Bell, J., Coombs, G., Bennett-Wood, V., Porter, J. L., Robins-Browne, R. M., Davies, J. K., Seemann, T. & Stinear, T. P., 2011, In : PLoS Pathogens. 7, 11 (Art. No: e1002359), p. 1 - 15 15 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
166 Citations (Scopus)

Necrotic enteritis-derived Clostridium perfringens strain with three closely related independently conjugative toxin and antibiotic resistance plasmids

Bannam, T. L., Yan, X., Harrison, P. F., Seemann, T., Keyburn, A. L., Stubenrauch, C., Weeramantri, L. H., Cheung, J. K-L., McClane, B. A., Boyce, J. D., Moore, R. J. & Rood, J. I., 2011, In : mBio. 2, 5, p. 1 - 9 9 p., e00190.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
57 Citations (Scopus)

The dominant Australian community-acquired methicillin-resistant Staphylococcus aureus clone ST93-IV [2B] is highly virulent and genetically distinct

Chua, K., Seemann, T., Harrison, P. F., Monagle, S., Korman, T. M., Johnson, P. D. R., Coombs, G. W., Howden, B. O., Davies, J. K., Howden, B. P. & Stinear, T. P., 2011, In : PLoS ONE. 6, 10 , 10 p., e25887.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
44 Citations (Scopus)
2010

Automated estimation of parasitaemia of Plasmodium yoelii-infected mice by digital image analysis of Giemsa-stained thin blood smears

Ma, C., Harrison, P. F., Wang, L. & Coppel, R. L., 2010, In : Malaria Journal. 9, Art. No: 348, p. 1 - 9 9 p.

Research output: Contribution to journalArticleResearchpeer-review

28 Citations (Scopus)

Colistin resistance in Acinetobacter baumannii is mediated by complete loss of lipopolysaccharide production

Moffatt, J. H., Harper, M., Harrison, P. F., Hale, J. DF., Vinogradov, E., Seemann, T., Henry, R. M., Crane, B. A., St Michael, F., Cox, A. D., Adler, B., Nation, R. L., Li, J. & Boyce, J. D., 2010, In : Antimicrobial Agents and Chemotherapy. 54, 12, p. 4971 - 4977 7 p.

Research output: Contribution to journalArticleResearchpeer-review

376 Citations (Scopus)

Complete genome sequence of Staphylococcus aureus strain JKD6008, an ST239 clone of methicillin-resistant Staphylococcus aureus with intermediate-level vancomycin resistance

Howden, B. P., Seemann, T., Harrison, P. F., McEvoy, C. R., Stanton, J. L., Rand, C., Mason, C. W., Jensen, S. O., Firth, N., Davies, J. K., Johnson, P. DR. & Stinear, T., 2010, In : Journal of Bacteriology. 192, 21, p. 5848 - 5849 2 p.

Research output: Contribution to journalArticleResearchpeer-review

41 Citations (Scopus)

Complete genome sequence of Staphylococcus aureus strain JKD6159, a unique Australian clone of ST93-IV community methicillin-resistant Staphylococcus aureus

Chua, K., Seemann, T., Harrison, P. F., Davies, J. K., Coutts, S. A. J., Chen, H., Haring, V., Moore, R., Howden, B. P. & Stinear, T. P., 2010, In : Journal of Bacteriology. 192, 20, p. 5556 - 5557 2 p.

Research output: Contribution to journalArticleResearchpeer-review

29 Citations (Scopus)

Fis is essential for capsule production in Pasteurella multocida and regulates expression of other important virulence factors

Steen, J. A., Steen, J. A., Harrison, P. F., Seemann, T., Wilkie, I. W., Harper, M., Adler, B. & Boyce, J. D., 2010, In : PLoS Pathogens. 6, 2, p. e1000750-1 - e1000750-14 14 p.

Research output: Contribution to journalArticleResearchpeer-review

48 Citations (Scopus)

Immune cell kinetics in the ovine abomasal mucosa following hyperimmunization and challenge with Haemonchus contortus

Robinson, N. A., Piedrafita, D. M., Snibson, K., Harrison, P. F. & Meeusen, E. N. T., 2010, In : Veterinary Research. 41, 4 (37), p. 1 - 10 10 p.

Research output: Contribution to journalArticleResearchpeer-review

25 Citations (Scopus)

Two novel point mutations in clinical Staphylococcus aureus reduce linezolid susceptibility and switch on the stringent response to promote persistent infection

Gao, W., Chua, K., Davies, J. K., Newton, H. J., Seemann, T., Harrison, P. F., Holmes, N. E., Rhee, H-W., Hong, J-I., Hartland, E. L., Stinear, T. P. & Howden, B. P., 2010, In : PLoS Pathogens. 6, 6 (e1000944), p. 1 - 15 15 p.

Research output: Contribution to journalArticleResearchpeer-review

127 Citations (Scopus)
2008

Dynamic reserve design with the union-find algorithm

Harrison, P. F., Spring, D. A., McKenzie, M. D. & Mac Nally, R. C., 2008, In : Ecological Modelling. 215, 4, p. 369 - 376 8 p.

Research output: Contribution to journalArticleResearchpeer-review

12 Citations (Scopus)

Insights from the complete genome sequence of Mycobacterium marinum on the evolution of Mycobacterium tuberculosis

Stinear, T. P., Seemann, T., Harrison, P. F., Jenkin, G. A., Davies, J. K., Johnson, P. D. R., Abdellah, Z., Arrowsmith, C., Chillingworth, T., Churcher, C., Clarke, K., Cronin, A., Davis, P., Goodhead, I., Holroyd, N., Jagels, K., Lord, A., Moule, S., Mungall, K., Norbertczak, H. & 11 others, Quail, M. A., Rabbinowitsch, E., Walker, D., White, B., Whitehead, S., Small, P. L. C., Brosch, R., Ramakrishnan, L., Fischbach, M. A., Parkhill, J. & Cole, S. T., 2008, In : Genome Research. 18, 5, p. 729 - 741 13 p.

Research output: Contribution to journalArticleResearchpeer-review

338 Citations (Scopus)

Insights from the complete genome sequence of Mycobacterium marinum on the evolution of Mycobacterium tuberculosis (Genome Research (2008) 18 (729-741))

Stinear, T. P., Seemann, T., Harrison, P. F., Jenkin, G. A., Davies, J. K., Johnson, P. D. R., Abdellah, Z., Arrowsmith, C., Chillingworth, T., Churcher, C., Clarke, K., Cronin, A., Davis, P., Goodhead, I., Holroyd, N., Jagels, K., Lord, A., Moule, S., Mungall, K., Norbertczak, H. & 11 others, Quail, M. A., Rabbinowitsch, E., Walker, D., White, B., Whitehead, S., Small, P. L. C., Brosch, R., Ramakrishnan, L., Fischbach, M. A., Parkhill, J. & Cole, S. T., 1 Oct 2008, In : Genome Research. 18, 10, 1 p.

Research output: Contribution to journalComment / DebateOtherpeer-review

Ocean urea fertilization for carbon credits poses high ecological risks

Glibert, P., Azanza, R., Burford, M., Furuya, K., Abal, E., Al-Azri, A., Al-Yamani, F., Andersen, P., Anderson, D., Beardall, J., Berg, G. M., Brand, L., Bronk, D., Brookes, J., Burkholder, J., Cembella, A., Cochlan, W., Collier, J., Collos, Y., Diaz, R. & 37 others, Doblin, M. A., Drennan, T., Dyhrman, S., Fukuyo, Y., Farnas, M., Galloway, J., Graneli, E., Ha, D. V., Hallegraeff, G., Harrison, J., Harrison, P., Heil, C., Heimann, K., Howarth, R., Jauzein, C., Kana, A., Kana, T., Kim, H., Kudela, R., Legrand, C., Mallin, M., Mulholland, M., Murray, S., O'Neil, J., Pitcher, G., Qi, Y., Rabalais, N., Raine, R., Seitzinger, S., Solomon, P., Solomon, C., Stoecker, D., Usup, G., Wilson, J., Yin, K., Zhou, M. & Zhu, M., 2008, In : Marine Pollution Bulletin. 56, 6, p. 1049 - 1056 8 p.

Research output: Contribution to journalArticleResearchpeer-review

42 Citations (Scopus)
2001

A non-hierarchical procedure for re-synthesis of complex textures

Harrison, P., 2001, Proceedings of The 9-th International Conference in Central Europe on Computer Graphics, Visualization and Computer Vision'2001. Skala, V. (ed.). Czech Republic: University of West Bohemia, p. 190 - 197 8 p.

Research output: Chapter in Book/Report/Conference proceedingConference PaperResearchpeer-review

2000

A Non-hierarchical Procedure for Re-synthesis of Complex Textures

Harrison, P., 2000, Clayton Vic Australia: Monash University. 16 p.

Research output: Book/ReportBookOther