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Projects 2012 2019

Research Output 2009 2019

Tranexamic acid is an active site inhibitor of urokinase plasminogen activator

Wu, G., Mazzitelli, B. A., Quek, A. J., Veldman, M. J., Conroy, P. J., Caradoc-Davies, T. T., Ooms, L. M., Tuck, K. L., Schoenecker, J. G., Whisstock, J. C. & Law, R. H. P., 12 Mar 2019, In : Blood Advances. 3, 5, p. 729-733 5 p.

Research output: Contribution to journalArticleResearchpeer-review

Crystal structure of TcpK in complex with oriT DNA of the antibiotic resistance plasmid pCW3

Traore, D. A. K., Wisniewski, J. A., Flanigan, S. F., Conroy, P. J., Panjikar, S., Mok, Y-F., Lao, C., Griffin, M. D. W., Adams, V., Rood, J. I. & Whisstock, J. C., 13 Sep 2018, In : Nature Communications. 9, 1, 11 p., 3732.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
File

Perforin proteostasis is regulated through its C2 domain: supra-physiological cell death mediated by T431D-perforin

Brennan, A. J., Law, R. H. P., Conroy, P. J., Noori, T., Lukoyanova, N., Saibil, H., Yagita, H., Ciccone, A., Verschoor, S., Whisstock, J. C., Trapani, J. A. & Voskoboinik, I., 7 Feb 2018, In : Cell Death and Differentiation. 25, p. 1517-1529 13 p.

Research output: Contribution to journalArticleResearchpeer-review

The first transmembrane region of complement component-9 acts as a brake on its self-assembly

Spicer, B. A., Law, R. H. P., Caradoc-Davies, T. T., Ekkel, S. M., Bayly-Jones, C., Pang, S-S., Conroy, P. J., Ramm, G., Radjainia, M., Venugopal, H., Whisstock, J. C. & Dunstone, M. A., 15 Aug 2018, In : Nature Communications. 9, 1, 7 p., 3266.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
File

Antibodies: From novel repertoires to defining and refining the structure of biologically important targets

Conroy, P. J., Law, R. H. P., Caradoc-Davies, T. T. & Whisstock, J. C., 1 Mar 2017, In : Methods. 116, p. 12-22 11 p.

Research output: Contribution to journalArticleResearchpeer-review