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Personal profile


Professor Patrick Kwan 

Department of Neuroscience research groups - Kwan Lab

Patrick is a Professor in the Van Cleef Centre for Nervous Diseases, Department of Neuroscience, within the Central Clinical School, and Consultant Neurologist and Head of the Epilepsy Clinic at Alfred Health.

He is a medical specialist in neurology and an international authority in epileptology and antiepileptic drug development. 

Professor Kwan’s research portfolio encompasses both applied basic science and clinical aspects to improve the treatment outcomes of epilepsy. His research is focused on understanding the effects of long term treatment, identifying factors that affect outcomes, mechanisms of drug resistance, identifying novel molecular targets for the treatment and prevention of epilepsy and translating research findings into the practice of personalized medicine for epilepsy.


Research area keywords

  • Neurology
  • Epilepsy
  • Drug Development

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Research Output

30 years of second-generation antiseizure medications: impact and future perspectives

Perucca, E., Brodie, M. J., Kwan, P. & Tomson, T., Jun 2020, In : The Lancet Neurology. 19, 6, p. 544-556 13 p.

Research output: Contribution to journalReview ArticleResearchpeer-review

1 Citation (Scopus)

Antiepileptic drugs are not independently associated with cognitive dysfunction

Foster, E., Malpas, C. B., Ye, K., Johnstone, B., Carney, P. W., Velakoulis, D., O'Brien, T. J. & Kwan, P., 10 Mar 2020, In : Neurology. 94, 10, p. e1051-e1061 11 p.

Research output: Contribution to journalArticleResearchpeer-review

Antiepileptic Drug Teratogenicity and De Novo Genetic Variation Load

Perucca, P., Anderson, A., Jazayeri, D., Hitchcock, A., Graham, J., Todaro, M., Tomson, T., Battino, D., Perucca, E., Ferri, M. M., Rochtus, A., Lagae, L., Canevini, M. P., Zambrelli, E., Campbell, E., Koeleman, B. P. C., Scheffer, I. E., Berkovic, S. F., Kwan, P., Sisodiya, S. M. & 6 others, Goldstein, D. B., Petrovski, S., Craig, J., Vajda, F. J. E., O'Brien, T. J. & the EpiPGX and EPIGEN Consortia, 1 Jun 2020, In : Annals of Neurology. 87, 6, p. 897-906 10 p.

Research output: Contribution to journalArticleResearchpeer-review

Emergency presentation of new onset versus recurrent undiagnosed seizures: A retrospective review

Holper, S., Foster, E., Chen, Z. & Kwan, P., Jun 2020, In : Emergency Medicine Australasia. 32, 3, p. 430–437 8 p.

Research output: Contribution to journalArticleResearchpeer-review

Epileptic Seizure Detection Using Convolutional Neural Network: A Multi-Biosignal study

Liu, Y., Sivathamboo, S., Goodin, P., Bonnington, P., Kwan, P., Kuhlmann, L., O'Brien, T., Perucca, P. & Ge, Z., 4 Feb 2020, Proceedings of the Australasian Computer Science Week Multiconference 2020, ACSW 2020. Forkan, A. (ed.). New York NY USA: Association for Computing Machinery (ACM), 8 p. 37

Research output: Chapter in Book/Report/Conference proceedingConference PaperResearch