Pasquale Fedele

ADJUNCT SENIOR LECTURER, Medicine Monash Health

EmailPasquale.Fedele@monash.edu

Research activity per year

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2 Active

Phase II Study of Blinatumomab as Induction Therapy in Adolescent and Young Adult Acute Lymphoblastic Leukaemia
Fedele, P.
19/11/19 → 18/11/24
Project: Research
A Phase 3, Randomized, Open-label, Multicenter Study Comparing Ponatinib versus Imatinib, Administered in Combination with Reduced-intensity Chemotherapy, in Patients with Newly Diagnosed Philadelphia Chromosome-positive Acute Lymphoblastic Leukemia (Ph+ ALL)
Fedele, P.
2/02/19 → 1/02/24
Project: Research

11 Article
3 Letter

Deep profiling of apoptotic pathways with mass cytometry identifies a synergistic drug combination for killing myeloma cells
Teh, C. E., Gong, J. N., Segal, D., Tan, T., Vandenberg, C. J., Fedele, P. L., Low, M. S. Y., Grigoriadis, G., Harrison, S. J., Strasser, A., Roberts, A. W., Huang, D. C. S., Nolan, G. P., Gray, D. H. D. & Ko, M. E., 1 Jul 2020, In : Cell Death and Differentiation. 27, 7, p. 2217-2233 17 p.
Research output: Contribution to journal › Article › Research › peer-review

5 Citations (Scopus)
Excellent outcomes of transformed lymphomas in the rituximab era without autologous stem cell transplantation: an Australian, single‐centre experience
Tedjaseputra, A., Gilbertson, M., Low, M., Fedele, P. L., Kumar, B., Simpson, I., Grigoriadis, G., Shortt, J., Opat, S. & Gregory, G. P., 1 Jul 2020, (Accepted/In press) In : Internal Medicine Journal. 29 p.
Research output: Contribution to journal › Article › Research › peer-review
IRF4 Activity Is Required in Established Plasma Cells to Regulate Gene Transcription and Mitochondrial Homeostasis
Low, M. S. Y., Brodie, E. J., Fedele, P. L., Liao, Y., Grigoriadis, G., Strasser, A., Kallies, A., Willis, S. N., Tellier, J., Shi, W., Gabriel, S., O'Donnell, K., Pitt, C., Nutt, S. L. & Tarlinton, D., 26 Nov 2019, In : Cell Reports. 29, 9, p. 2634-2645.e5 18 p.
Research output: Contribution to journal › Article › Research › peer-review

Open Access
File

5 Citations (Scopus)
Failure to achieve early disease response is associated with inferior survival in patients with newly diagnosed multiple myeloma
Chee, A., Low, M. S., Vilcassim, S., Gregory, G. P., Gilbertson, M., Ratnasingam, S., Grigoriadis, G. & Fedele, P. L., Sep 2018, In : British Journal of Haematology. 182, 5, p. 739-741 3 p.
Research output: Contribution to journal › Article › Other › peer-review

1 Citation (Scopus)
IMiDs prime myeloma cells for daratumumab-mediated cytotoxicity through loss of Ikaros and Aiolos
Fedele, P. L., Willis, S. N., Liao, Y., Low, M. S., Rautela, J., Segal, D. H., Gong, J. N., Huntington, N. D., Shi, W., Huang, D. C. S., Grigoriadis, G., Tellier, J. & Nutt, S. L., 15 Nov 2018, In : Blood. 132, 20, p. 2166-2178 13 p.
Research output: Contribution to journal › Article › Research › peer-review

Open Access
File

22 Citations (Scopus)

Phase II Study of Blinatumomab as Induction Therapy in Adolescent and Young Adult Acute Lymphoblastic Leukaemia

A Phase 3, Randomized, Open-label, Multicenter Study Comparing Ponatinib versus Imatinib, Administered in Combination with Reduced-intensity Chemotherapy, in Patients with Newly Diagnosed Philadelphia Chromosome-positive Acute Lymphoblastic Leukemia (Ph+ ALL)

Deep profiling of apoptotic pathways with mass cytometry identifies a synergistic drug combination for killing myeloma cells

Excellent outcomes of transformed lymphomas in the rituximab era without autologous stem cell transplantation: an Australian, single‐centre experience

IRF4 Activity Is Required in Established Plasma Cells to Regulate Gene Transcription and Mitochondrial Homeostasis

Failure to achieve early disease response is associated with inferior survival in patients with newly diagnosed multiple myeloma

IMiDs prime myeloma cells for daratumumab-mediated cytotoxicity through loss of Ikaros and Aiolos