• 15 Innovation Walk, Level 3, Rm-376

    3800 Clayton

    Australia

Accepting PhD Students

20072021
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Research Output 2007 2019

2019
1 Citation (Scopus)

TAF5L and TAF6L Maintain Self-Renewal of Embryonic Stem Cells via the MYC Regulatory Network

Seruggia, D., Oti, M., Tripathi, P., Canver, M. C., LeBlanc, L., Di Giammartino, D. C., Bullen, M. J., Nefzger, C. M., Sun, Y. B. Y., Farouni, R., Polo, J. M., Pinello, L., Apostolou, E., Kim, J., Orkin, S. H. & Das, P. P., 20 Jun 2019, In : Molecular Cell. 74, 6, p. 1148-1163 16 p.

Research output: Contribution to journalArticleResearchpeer-review

2018
4 Citations (Scopus)

Inhibition of a K9/K36 demethylase by an H3.3 point mutation found in paediatric glioblastoma

Voon, H. P. J., Udugama, M., Lin, W., Hii, L., Law, R. H. P., Steer, D. L., Das, P. P., Mann, J. R. & Wong, L. H., 1 Dec 2018, In : Nature Communications. 9, 1, 10 p., 3142.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
File
2017
20 Citations (Scopus)

The histone demethylase UTX regulates the lineage-specific epigenetic program of invariant natural killer T cells

Beyaz, S., Kim, J. H., Pinello, L., Xifaras, M. E., Hu, Y., Huang, J., Kerenyi, M. A., Das, P. P., Barnitz, R. A., Herault, A., Dogum, R., Haining, W. N., Yilmaz, Ö. H., Passegue, E., Yuan, G. C., Orkin, S. H. & Winau, F., 1 Feb 2017, In : Nature Immunology. 18, 2, p. 184-195 12 p.

Research output: Contribution to journalArticleResearchpeer-review

42 Citations (Scopus)

Variant-aware saturating mutagenesis using multiple Cas9 nucleases identifies regulatory elements at trait-associated loci

Canver, M. C., Lessard, S., Pinello, L., Wu, Y., Ilboudo, Y., Stern, E. N., Needleman, A. J., Galactéros, F., Brugnara, C., Kutlar, A., McKenzie, C., Reid, M., Chen, D. D., Das, P. P., A Cole, M., Zeng, J., Kurita, R., Nakamura, Y., Yuan, G. C., Lettre, G. & 2 others, Bauer, D. E. & Orkin, S. H., Apr 2017, In : Nature Genetics. 49, 4, p. 625-634 10 p.

Research output: Contribution to journalArticleResearchpeer-review

2016
27 Citations (Scopus)

Chronic myelogenous leukemia-initiating cells require polycomb group protein EZH2

Xie, H., Peng, C., Huang, J., Li, B. E., Kim, W., Smith, E. C., Fujiwara, Y., Qi, J., Cheloni, G., Das, P. P., Nguyen, M., Li, S., Bradner, J. E. & Orkin, S. H., 1 Nov 2016, In : Cancer Discovery. 6, 11, p. 1237-1247 11 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
File
2015
27 Citations (Scopus)

Flow-induced protein kinase A-CREB pathway acts via BMP signaling to promote HSC emergence

Kim, P. G., Nakano, H., Das, P. P., Chen, M. J., Rowe, R. G., Chou, S. S., Ross, S. J., Sakamoto, K. M., Zon, L. I., Schlaeger, T. M., Orkin, S. H., Nakano, A. & Daley, G. Q., 4 May 2015, In : Journal of Experimental Medicine. 212, 5, p. 633-648 16 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
File
16 Citations (Scopus)

Functional proteomic analysis of repressive histone methyltransferase complexes reveals ZNF518B as a G9A regulator

Maier, V. K., Feeney, C. M., Taylor, J. E., Creech, A. L., Qiao, J. W., Szanto, A., Das, P. P., Chevrier, N., Cifuentes-Rojas, C., Orkin, S. H., Carr, S. A., Jaffe, J. D., Mertins, P. & Lee, J. T., 1 Jun 2015, In : Molecular & Cellular Proteomics. 14, 6, p. 1435-1446 12 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
File
25 Citations (Scopus)

PRC2 Is Required to Maintain Expression of the Maternal Gtl2-Rian-Mirg Locus by Preventing De Novo DNA Methylation in Mouse Embryonic Stem Cells

Das, P. P., Hendrix, D. A., Apostolou, E., Buchner, A. H., Canver, M. C., Beyaz, S., Ljuboja, D., Kuintzle, R., Kim, W., Karnik, R., Shao, Z., Xie, H., Xu, J., De Los Angeles, A., Zhang, Y., Choe, J., Jun, D. L. J., Shen, X., Gregory, R. I., Daley, G. Q. & 5 others, Meissner, A., Kellis, M., Hochedlinger, K., Kim, J. & Orkin, S. H., 1 Sep 2015, In : Cell Reports. 12, 9, p. 1456-1470 15 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
File
2014
55 Citations (Scopus)

Distinct and Combinatorial Functions of Jmjd2b/Kdm4b and Jmjd2c/Kdm4c in Mouse Embryonic Stem Cell Identity

Das, P. P., Shao, Z., Beyaz, S., Apostolou, E., Pinello, L., De Los Angeles, A., O’Brien, K., Marino Atsma, J., Fujiwara, Y., Nguyen, M., Ljuboja, D., Guo, G., Woo, A., Yuan, G. C., Onder, T., Daley, G., Hochedlinger, K., Kim, J. & Orkin, S. H., 9 Jan 2014, In : Molecular Cell. 53, 1, p. 32-48 17 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
File
2013
143 Citations (Scopus)

Mapping cellular hierarchy by single-cell analysis of the cell surface repertoire

Guo, G., Luc, S., Marco, E., Lin, T-W., Peng, C., Kerenyi, M. A., Beyaz, S., Kim, W., Xu, J., Das, P. P., Neff, T., Zou, K., Yuan, G. C. & Orkin, S. H., 3 Oct 2013, In : Cell Stem Cell. 13, 4, p. 492-505 14 p.

Research output: Contribution to journalArticleResearchpeer-review

2008
72 Citations (Scopus)

Maternal argonaute 2 is essential for early mouse development at the maternal-zygotic transition

Lykke-Andersen, K., Gilchrist, M. J., Grabarek, J. B., Das, P., Miska, E. & Zernicka-Goetz, M., 1 Oct 2008, In : Molecular Biology of the Cell. 19, 10, p. 4383-4392 10 p.

Research output: Contribution to journalArticleResearchpeer-review

296 Citations (Scopus)

MicroRNA biogenesis is required for mouse primordial germ cell development and spermatogenesis

Hayashi, K., Chuva de Sousa Lopes, S. M., Kaneda, M., Tang, F., Hajkova, P., Lao, K., O'Carroll, D., Das, P. P., Tarakhovsky, A., Miska, E. A. & Surani, M. A., 5 Mar 2008, In : PLoS ONE. 3, 3, e1738.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
222 Citations (Scopus)

Piwi and piRNAs Act Upstream of an Endogenous siRNA Pathway to Suppress Tc3 Transposon Mobility in the Caenorhabditis elegans Germline

Das, P. P., Bagijn, M. P., Goldstein, L. D., Woolford, J. R., Lehrbach, N. J., Sapetschnig, A., Buhecha, H. R., Gilchrist, M. J., Howe, K. L., Stark, R., Matthews, N., Berezikov, E., Ketting, R. F., Tavaré, S. & Miska, E. A., 11 Jul 2008, In : Molecular Cell. 31, 1, p. 79-90 12 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
2007
263 Citations (Scopus)

A Slicer-independent role for Argonaute 2 in hematopoiesis and the microRNA pathway

O'Carroll, D., Mecklenbrauker, I., Das, P. P., Santana, A., Koenig, U., Enright, A. J., Miska, E. A. & Tarakhovsky, A., 15 Aug 2007, In : Genes and Development. 21, 16, p. 1999-2004 6 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
711 Citations (Scopus)

Genetic unmasking of an epigenetically silenced microRNA in human cancer cells

Lujambio, A., Ropero, S., Ballestar, E., Fraga, M. F., Cerrato, C., Setién, F., Casado, S., Suarez-Gauthier, A., Sanchez-Cespedes, M., Gitt, A., Spiteri, I., Das, P. P., Caldas, C., Miska, E. & Esteller, M., 15 Feb 2007, In : Cancer Research. 67, 4, p. 1424-1429 6 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
541 Citations (Scopus)

microRNA-155 Regulates the Generation of Immunoglobulin Class-Switched Plasma Cells

Vigorito, E., Perks, K. L., Abreu-Goodger, C., Bunting, S., Xiang, Z., Kohlhaas, S., Das, P. P., Miska, E. A., Rodriguez, A., Bradley, A., Smith, K. G. C., Rada, C., Enright, A. J., Toellner, K. M., MacLennan, I. C. M. & Turner, M., 21 Dec 2007, In : Immunity. 27, 6, p. 847-859 13 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
1349 Citations (Scopus)

Requirement of bic/microRNA-155 for normal immune function

Rodriguez, A., Vigorito, E., Clare, S., Warren, M. V., Couttet, P., Soond, D. R., Van Dongen, S., Grocock, R. J., Das, P. P., Miska, E. A., Vetrie, D., Okkenhaug, K., Enright, A. J., Dougan, G., Turner, M. & Bradley, A., 27 Apr 2007, In : Science. 316, 5824, p. 608-611 4 p.

Research output: Contribution to journalArticleResearchpeer-review