Projects per year
Personal profile
Biography
Dr Murthi is a Senior Research Fellow within the Fibrosis Laboratory at the Department of Pharmacology. Dr Murthi is working with A/Prof Chrishan Samuel on the NHMRC funded project on "enhancing the anti-fibrotic and regenerative capcity of bone-marrow derived stem cells". Dr Murthi will also "evaluate the peptide-based anti-fibrotics in treating cardiac, kidney and lung fibrosis".
Dr Murthi is a reproductive biologist and placentologist with research expertise in placental development and function in human idiopathic fetal growth restriction (FGR) and has generated more than 100 publications in this field. FGR significantly contributes to higher incidence of metabolic, renal and cardiovascular diseases (CVD) later in life. Dr Murthi's long term research aim is to develop and deliver novel peptides as targted therapeutics to improve cardiac and vascular structure and function in individuals with FGR. A more detailed knowledge of underlying disease mechanisms is likely to advance prevention and treatment of FGR and its complications, and thereby improve long-term out-comes for patients with FGR.
Dr Murthi was awarded a PhD in 1995 from the University of Melbourne under the supervision of Prof Richard Larkins. From 2000 to 2014, Dr Murthi was employed at the Department of Obstetrics and Gynaecology, University of Melbourne and the Department of Maternal-Fetal Medicine, Royal Women's Hospital. In 2015-2018, she was recruited to Monash University within the Department of Medicine, School of Clinical Sciences and the Ritchie Centre, Hudson Institute of Medical Research as a Senior Research Fellow and as a Teaching Associate.
Dr Murthi also serves on the editorial boards of reproductive biology journals, Placenta and International Journal of Reproductive Sciences and Scientific Reprots. She is the elected secretary of International Federation of Placental Associations (IFPA) and act as a chair person of the IFPA award committee.
Education/Academic qualification
Education, Graduate Certificate in Higher Education, Victoria University
Award Date: 15 May 2020
Medicine, PhD, University of Melbourne
Award Date: 4 Nov 1994
Medicine, MPhil, University of Madras, Chennai, India
Award Date: 3 Jun 1988
Biochemistry, MSc, University of Madras, Chennai, India
Award Date: 30 Dec 1986
Zoology, BSc, University of Madras, Chennai, India
Award Date: 15 Jun 1984
Network
Recent external collaboration on country level. Dive into details by clicking on the dots.
Projects
- 4 Finished
Biodistribution of Cynata-MSCs following intra-muscular injection to mice
22/04/19 → 30/06/19
Project: Research
Investigating the role of novel peptide receptor as an effective target to improve placental function in preeclampsia.
1/01/17 → 31/12/17
Project: Research
The role of placental proteoglycans in diabetic vasculopathy
The Australasian diabetes in Pregnancy Society ADIPS
1/03/15 → 27/07/16
Project: Research
Investigating the role of altered proteoglycan function in diabetic placental vasculopathy
Murthi, P. & Said, J. M.
1/03/15 → 3/03/15
Project: Research
Research Output
Inflammasomes—a molecular link for altered immunoregulation and inflammation mediated vascular dysfunction in preeclampsia
Murthi, P., Pinar, A. A., Dimitriadis, E. & Samuel, C. S., 19 Feb 2020, In : International Journal of Molecular Sciences. 21, 4, 18 p., 1406.Research output: Contribution to journal › Review Article › Research › peer-review
Open Access
File
Placental serotonin systems in pregnancy metabolic complications associated with maternal obesity and gestational diabetes mellitus
Murthi, P. & Vaillancourt, C., 1 Feb 2020, In : Biochimica et Biophysica Acta - Molecular Basis of Disease. 1866, 2, 8 p., 165391.Research output: Contribution to journal › Review Article › Research › peer-review
5
Citations
(Scopus)
The Effects of Early-Onset Pre-Eclampsia on Placental Creatine Metabolism in the Third Trimester
Ellery, S. J., Murthi, P., Gatta, P. A. D., May, A. K., Davies-Tuck, M. L., Kowalski, G. M., Callahan, D. L., Bruce, C. R., Wallace, E. M., Walker, D. W., Dickinson, H. & Snow, R. J., 26 Jan 2020, In : International Journal of Molecular Sciences. 21, 3, 14 p., 806.Research output: Contribution to journal › Article › Research › peer-review
Open Access
File
Decreased placental glypican expression is associated with human fetal growth restriction
Gunatillake, T., Chui, A., Fitzpatrick, E., Ignjatovic, V., Monagle, P., Whitelock, J., Zanten, D., Eijsink, J., Borg, A., Stevenson, J., Brennecke, S. P., Erwich, J. J. H. M., Said, J. M. & Murthi, P., 15 Jan 2019, In : Placenta. 76, p. 6-9 4 p.Research output: Contribution to journal › Article › Research › peer-review
1
Citation
(Scopus)
Disrupted placental serotonin synthetic pathway and increased placental serotonin: Potential implications in the pathogenesis of human fetal growth restriction
Ranzil, S., Ellery, S., Walker, D. W., Vaillancourt, C., Alfaidy, N., Bonnin, A., Borg, A., Wallace, E. M., Ebeling, P. R., Erwich, J. J. & Murthi, P., 1 Sep 2019, In : Placenta. 84, p. 74-83 10 p.Research output: Contribution to journal › Review Article › Research › peer-review
3
Citations
(Scopus)