Projects per year
Personal profile
Biography
Assoc. Prof. Ooi Chien Wei specializes in the fields of bioprocess design and biocatalysis. His research focus is on the development of integrated microbial fermentation systems and bioprocess model prediction tools for the expression of industrially important enzymes and proteins derived from recombinant DNA technology. His research also involves the applications of bio-derived ionic liquids and stimuli-responsive polymers in the designs of novel bioprocesses, bioseparation systems and biosensing materials. Aside from the field of bioprocess engineering, his research focuses on the development of food-grade emulsion systems and the extraction technologies applied in food waste valorization and recovery of phytonutrients from microalgal source and agrowastes. He has been working with the industrial partners in the development of smart hydrogels for glove application and in the transformation of chemical synthesis routes by biocatalysis strategy, ranging from enzyme engineering to molecular dynamic simulations. He has published more than 90 ISI-indexed journals, and holds 6 patents related to bioprocess technology, biomass processing and smart hydrogel application. He has secured multiple research grants from government and industry worth more than RM680,000 as principle investigator.
Research interests
- Bioseparation and bioprocess engineering
- Downstream processing of proteins
- Bioprocess integration
- Enzyme technology
- Biomass valorization
- Biosensors
Monash teaching commitment
- ENG1010 - Process System Analysis (2012)
- CHE2165 - Bionano Engineering (2012 - 2015)
- CHE2871 - Biochemistry for Engineers (2017 - present)
- CHE4162 - Particle Technology (2011 - 2016)
- CHE4171 - Biochemical Engineering (2014 - present)
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
Education/Academic qualification
Graduate Certificate in Higher Education, Monash University Malaysia
Award Date: 1 Jul 2013
Process and Food Engineering, Ph.D. in Bioprocess Engineering , Universiti Putra Malaysia (University Putra Malaysia)
Award Date: 12 May 2011
B.Sc. (Hons) in Biotechnology, Universiti Tunku Abdul Rahman (UTAR) (Tunku Abdul Rahman University)
Award Date: 31 Jul 2007
Research area keywords
- Bioseparation and bioprocess engineering
- Downstream processing of proteins
- Bioprocess integration
- Enzyme technology
- Polymer chemistry
- Biomass valorization
- Biosensors
- Ooi C.W.
- Ooi Chien-Wei
- Chien Wei Ooi
- Ooi, Chien-Wei
- Ooi Chien Wei
Collaborations and top research areas from the last five years
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Development of a One-Pot Enzymatic Approach for the Delignification and Bioconversion of Lignocellulose into Bioproducts
Chien Wei (Edward), O. (Primary Chief Investigator (PCI)) & Sewn Cen, L. (Chief Investigator (CI))
1/08/25 → 31/07/26
Project: Research
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Bioconversion of Oil Palm Waste into Valuable Low-carbon Products
Chien Wei (Edward), O. (Primary Chief Investigator (PCI)) & Sewn Cen, L. (Chief Investigator (CI))
1/02/25 → 31/05/26
Project: Research
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Production of high value thiochemicals using bio-chemical process
Chien Wei (Edward), O. (Primary Chief Investigator (PCI)), Eng Seng, C. (Chief Investigator (CI)) & Beng Ti, T. (Chief Investigator (CI))
1/08/23 → 31/07/26
Project: Research
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Molecular Dynamics Simulation Studies of Thermostabilization of Industrially Important Proteins by Cholinium-based Ionic Liquids
Chien Wei (Edward), O. (Primary Chief Investigator (PCI)), Ranganathan, V. (Chief Investigator (CI)), Macfarlane, D. (Chief Investigator (CI)), Ho Yong Kuen, J. (Chief Investigator (CI)), Sundaram, V. (Chief Investigator (CI)) & Naga Sundararamanan, R. (Chief Investigator (CI))
1/01/19 → 31/03/23
Project: Research
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An investigation of global limiting factors in fermentation process for recombinant protein production in periplasm of Escherichia coli
Beng Ti, T. (Primary Chief Investigator (PCI)), Chien Wei (Edward), O. (Chief Investigator (CI)), Arif, A. (Chief Investigator (CI)) & Song, J. (Chief Investigator (CI))
1/08/16 → 31/07/19
Project: Research
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Hybridizing O-C3N4 with NIR-responsive Cu2(OH)PO4 for effective broad-spectrum solar driven inactivation of Escherichia coli and methicillin-resistant Staphylococcus aureus
Dahlan, N. A. N., Putri, L. K., Ooi, C. W., Tan, L. L. & Chai, S. P., 7 Feb 2026, In: Separation and Purification Technology. 380, Part 3, 15 p., 135447.Research output: Contribution to journal › Article › Research › peer-review
Open Access -
Affordable CO2-derived alkyl carbamate ionic liquids boosting enzymatic production of renewable hydrocarbon fuels via Chlorella variabilis NC64A fatty acid photodecarboxylase (CVFAP)
Ng, W. Z., Chan, E. S., Liow, M. Y., Ooi, C. W., Tey, B. T. & Song, C. P., May 2025, In: International Journal of Biological Macromolecules. 305, Part 1, 10 p., 141187.Research output: Contribution to journal › Article › Research › peer-review
Open Access1 Citation (Scopus) -
Effects of oxidation inducers on palm, jatropha, and sunflower biodiesel properties during 22-week storage and improvements with antioxidants
Laemthong, T., Chiarasamran, N., Saisriyoot, M., Thanapimmetha, A., Ooi, C. W., Chang, Y. K. & Srinophakun, P., May 2025, In: Biofuels, Bioproducts and Biorefining. 19, 3, p. 678-689 12 p.Research output: Contribution to journal › Article › Research › peer-review
2 Citations (Scopus) -
Elliptical electrode designs in quartz crystal microbalances: Enhancing sensitivity in liquid biosensing applications
Ahamed, A., Ooi, C. W., Lim, H. J., Ramakrishnan, N. & Saha, T., 1 Jun 2025, In: Sensors and Actuators A: Physical. 387, 9 p., 116392.Research output: Contribution to journal › Article › Research › peer-review
Open Access1 Citation (Scopus) -
In situ loading of lipase onto polycaprolactone nanofibers via alternate electrospin-electrospray for enzymatic self-degradable air filtration membranes
Thew, C. X. E., Lo, S. C., Palaniandy, K., Pasbakhsh, P. & Ooi, C. W., Jun 2025, In: International Journal of Biological Macromolecules. 317, Part 1, 10 p., 144679.Research output: Contribution to journal › Article › Research › peer-review
Open Access1 Citation (Scopus)
Prizes
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Monash-Sunway Decarbonization initiative: Microalgae farming and Native Tree Planting
Foo, S. C. (Recipient), Barclay, H. (Recipient), Meng Nan, C. (Recipient), Chien Wei (Edward), O. (Recipient), Ilankoon, S. (Recipient), Watabe, M. (Recipient), Lian, T. C. (Recipient) & Rahman, S. (Recipient), 23 Aug 2018
Prize: Other distinction
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