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Research Output

2017

First person - Olivia Susanto

Susanto, O., 1 Jan 2017, In : Journal of Cell Science. 130, 20, p. 3421-3422 2 p.

Research output: Contribution to journalArticleOtherpeer-review

LPP3 mediates self-generation of chemotactic LPA gradients by melanoma cells

Susanto, O., Koh, Y. W. H., Morrice, N., Tumanov, S., Thomason, P. A., Nielson, M., Tweedy, L., Muinonen-Martin, A. J., Kamphorst, J. J., Mackay, G. M. & Insall, R. H., 1 Jan 2017, In : Journal of Cell Science. 130, 20, p. 3455-3466 12 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
File
16 Citations (Scopus)
2016

Self-generated chemotactic gradients - cells steering themselves

Tweedy, L., Susanto, O. & Insall, R. H., 1 Oct 2016, In : Current Opinion in Cell Biology. 42, p. 46-51 6 p.

Research output: Contribution to journalReview ArticleOtherpeer-review

13 Citations (Scopus)

Visualizing cancer cell chemotaxis and invasion in 2D and 3D

Susanto, O., Muinonen-Martin, A. J., Nobis, M. & Insall, R. H., 1 Jan 2016, Methods in Molecular Biology. Jin, T. & Hereld, D. (eds.). New York, NY: Humana Press, p. 217-228 12 p. (Methods in Molecular Biology; vol. 1407).

Research output: Chapter in Book/Report/Conference proceedingChapter (Book)Otherpeer-review

4 Citations (Scopus)
2014

A functional genomics screen identifies PCAF and ADA3 as regulators of human granzyme B-mediated apoptosis and Bid cleavage

Brasacchio, D., Noori, T., House, C. M., Brennan, A. J., Simpson, K. J., Susanto, O., Bird, P. I., Johnstone, R. W. & Trapani, J. A., 2014, In : Cell Death and Differentiation. 21, 5, p. 748 - 760 13 p.

Research output: Contribution to journalArticleResearchpeer-review

12 Citations (Scopus)

Melanoma Cells Break Down LPA to Establish Local Gradients That Drive Chemotactic Dispersal

Muinonen-Martin, A. J., Susanto, O., Zhang, Q., Smethurst, E., Faller, W. J., Veltman, D. M., Kalna, G., Lindsay, C., Bennett, D. C., Sansom, O. J., Herd, R., Jones, R., Machesky, L. M., Wakelam, M. J. O., Knecht, D. A. & Insall, R. H., 1 Jan 2014, In : PLoS Biology. 12, 10, 17 p., e1001966.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
File
56 Citations (Scopus)
2013

Mouse granzyme A induces a novel death with writhing morphology that is mechanistically distinct from granzyme B-induced apoptosis

Susanto, O., Stewart, S. E., Voskoboinik, I., Brasacchio, D., Hagn, M., Ellis, S. L., Asquith, S., Sedelies, K. A., Bird, P. I., Waterhouse, N. J. & Trapani, J. A., 2013, In : Cell Death and Differentiation. 20, 9, p. 1183 - 1193 11 p.

Research output: Contribution to journalArticleResearchpeer-review

27 Citations (Scopus)

Perforin forms transient pores on the target cell plasma membrane to facilitate rapid access of granzymes during killer cell attack

Lopez, J., Susanto, O., Jenkins, M., Lukoyanova, N., Sutton, V. R., Law, R. H. P., Johnston, A., Bird, C. H., Bird, P. I., Whisstock, J., Trapani, J. A., Saibil, H. & Voskoboinik, I., 2013, In : Blood. 121, 14, p. 2659 - 2668 10 p.

Research output: Contribution to journalArticleResearchpeer-review

100 Citations (Scopus)
2012

Controversies in granzyme biology

Susanto, O., Trapani, J. A. & Brasacchio, D., Dec 2012, In : Tissue Antigens. 80, 6, p. 477-487 11 p.

Research output: Contribution to journalArticleResearchpeer-review

43 Citations (Scopus)
2011

Protection from endogenous perforin: Glycans and the C terminus regulate exocytic trafficking in cytotoxic lymphocytes

Brennan, A., Chia, J., Browne, K., Ciccone, A., Ellis, S. L., Lopez, J., Susanto, O., Verschoor, S., Yagita, H., Whisstock, J., Trapani, J. & Voskoboinik, I., 2011, In : Immunity. 34, 6, p. 879 - 892 14 p.

Research output: Contribution to journalArticleResearchpeer-review

42 Citations (Scopus)
2009

Granule-mediated death by cytotoxic lymphocytes does not require mitochondrial polarization toward the immunologic synapse in target cells

Susanto, O., Sedelies, K., Trapani, J. & Waterhouse, N., 12 Feb 2009, In : Blood. 113, 7, p. 1609-1611 3 p.

Research output: Contribution to journalLetterOtherpeer-review

2008

Blocking granule-mediated death by primary human NK cells requires both protection of mitochondria and inhibition of caspase activity

Sedelies, K. A., Ciccone, A., Clarke, C. J. P., Oliaro, J., Sutton, V. R., Scott, F. L., Silke, J., Susanto, O., Green, D. R., Johnstone, R. W., Bird, P. I., Trapani, J. A. & Waterhouse, N. J., 2008, In : Cell Death and Differentiation. 15, 4, p. 708 - 717 10 p.

Research output: Contribution to journalArticleResearchpeer-review

27 Citations (Scopus)