20042019
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Research Output 2004 2019

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2019

Paclitaxel-Induced Src Activation Is Inhibited by Dasatinib Treatment, Independently of Cancer Stem Cell Properties, in a Mouse Model of Ovarian Cancer

Kadife, E., Chan, E., Luwor, R., Kannourakis, G., Findlay, J. K. & Ahmed, N., 19 Feb 2019, In : Cancers. 11, 2, p. 1-24 24 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
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2018
5 Citations (Scopus)

Momelotinib decreased cancer stem cell associated tumor burden and prolonged disease-free remission period in a mouse model of human ovarian cancer

Chan, E., Luwor, R., Burns, C., Kannourakis, G., Findlay, J. K. & Ahmed, N., 30 Mar 2018, In : Oncotarget. 9, 24, p. 16599-16618 20 p.

Research output: Contribution to journalArticleResearchpeer-review

2017
8 Citations (Scopus)

Knockdown of stem cell regulator Oct4A in ovarian cancer reveals cellular reprogramming associated with key regulators of cytoskeleton-extracellular matrix remodelling

Samardzija, C., Greening, D. W., Escalona, R., Chen, M., Bilandzic, M., Luwor, R. B., Kannourakis, G., Findlay, J. K. & Ahmed, N., 13 Apr 2017, In : Scientific Reports. 7, 18 p., 46312.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
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2016
3 Citations (Scopus)

Coalition of Oct4A and β1 integrins in facilitating metastasis in ovarian cancer

Samardzija, C., Luwor, R. B., Quinn, M. A., Kannourakis, G., Findlay, J. & Ahmed, N., 8 Jul 2016, In : BMC Cancer. 16, 1, 16 p., 432.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
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11 Citations (Scopus)

Unique proteome signature of post-chemotherapy ovarian cancer ascites-derived tumor cells

Ahmed, N., Greening, D., Samardzija, C., Escalona, R. M., Chen, M., Findlay, J. K. & Kannourakis, G., 29 Jul 2016, In : Scientific Reports. 6, 13 p., 30061.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
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2015
17 Citations (Scopus)

A critical role of Oct4A in mediating metastasis and disease-free survival in a mouse model of ovarian cancer

Samardzija, C., Luwor, R. B., Volchek, M., Quinn, M. A., Findlay, J. J. K. & Ahmed, N., 2015, In : Molecular Cancer. 14, p. 1 - 19 19 p., 152.

Research output: Contribution to journalArticleResearchpeer-review

Open Access

Enhanced activation of STAT3 in ascites-derived recurrent ovarian tumors: inhibition of cisplatin-induced STAT3 activation reduced tumorigenicity of ovarian cancer by a loss of cancer stem cell-like characteristics

Abubaker, K., Latifi, A., Chan, E., Luwor, R. B., Burns, C. J., Thompson, E. W., Findlay, J. J. K. & Ahmed, N., 2015, In : Journal of Cancer Stem Cell Research. 3, 17 p., e1001.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
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2014
16 Citations (Scopus)

Betaglycan blocks metastatic behaviors in human granulosa cell tumors by suppressing NF?B-mediated induction of MMP2

Bilandzic, M., Wang, Y., Ahmed, N., Luwor, R. B., Zhu, H-J., Findlay, J. J. K. & Stenvers, K. L., 2014, In : Cancer Letters. 354, 1, p. 107 - 114 8 p.

Research output: Contribution to journalArticleResearchpeer-review

18 Citations (Scopus)

Granulocyte colony-stimulating factor receptor signalling via Janus kinase 2/signal transducer and activator of transcription 3 in ovarian cancer

Kumar, J., Fraser, F. W., Riley, C., Ahmed, N., McCulloch, D. R. & Ward, A. C., 7 Jan 2014, In : British Journal of Cancer. 110, 1, p. 133-145 13 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
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64 Citations (Scopus)

Inhibition of the JAK2/STAT3 pathway in ovarian cancer results in the loss of cancer stem cell-like characteristics and a reduced tumor burden

Abubaker, K., Luwor, R. B., Zhu, H-J., McNally, O. M., Quinn, M. A., Burns, C. J., Thompson, E. W., Findlay, J. K. & Ahmed, N., 6 May 2014, In : BMC Cancer. 14, 1, 22 p., 317.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
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32 Citations (Scopus)

Targeted disruption of the JAK2/STAT3 pathway in combination with systemic administration of paclitaxel inhibits the priming of ovarian cancer stem cells leading to a reduced tumor burden

Abubaker, K., Luwor, R. B., Escalona, R., McNally, O., Quinn, M. A., Thompson, E. W., Findlay, J. K. & Ahmed, N., 2014, In : Frontiers in Oncology. 4 APR, 12 p., Article 75.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
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2013
143 Citations (Scopus)

Getting to know ovarian cancer ascites: opportunities for targeted therapy-based translational research

Ahmed, N. & Stenvers, K. L., 2013, In : Frontiers in Oncology. 3, Art. No.: 256, p. 1 - 12 12 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
113 Citations (Scopus)

Short-term single treatment of chemotherapy results in the enrichment of ovarian cancer stem cell-like cells leading to an increased tumor burden

Abubaker, K., Latifi, A., Luwor, R., Nazaretian, S., Zhu, H., Quinn, M. A., Thompson, E. W., Findlay, J. K. & Ahmed, N., 27 Mar 2013, In : Molecular Cancer. 12, 1, 24.

Research output: Contribution to journalArticleResearchpeer-review

2012
38 Citations (Scopus)

Contribution of fibroblast and mast cell (afferent) and tumor (efferent) IL-6 effects within the tumor microenvironment

Hugo, H. J., Lebret, S., Tomaskovic-Crook, E., Ahmed, N., Blick, T., Newgreen, D. F., Thompson, E. W. & Ackland, M. L., Apr 2012, In : Cancer Microenvironment. 5, 1, p. 83-93 11 p.

Research output: Contribution to journalArticleResearchpeer-review

108 Citations (Scopus)

Isolation and Characterization of Tumor Cells from the Ascites of Ovarian Cancer Patients: Molecular Phenotype of Chemoresistant Ovarian Tumors

Latifi, A., Luwor, R. B., Bilandzic, M., Nazaretian, S., Stenvers, K., Pyman, J. M., Zhu, H., Thompson, E. W., Quinn, M. A., Findlay, J. K. & Ahmed, N., 8 Oct 2012, In : PLoS ONE. 7, 10, e46858.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
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2011
17 Citations (Scopus)

2D-PAGE of ovarian cancer: Analysis of soluble and insoluble fractions using medium-range immobilized pH gradients

Lim, R., Lappas, M., Ahmed, N., Permezel, M., Quinn, M. A. & Rice, G. E., 18 Mar 2011, In : Biochemical and Biophysical Research Communications. 406, 3, p. 408-413 6 p.

Research output: Contribution to journalArticleResearchpeer-review

147 Citations (Scopus)

Cisplatin treatment of primary and metastatic epithelial ovarian carcinomas generates residual cells with mesenchymal stem cell-like profile

Latifi, A., Abubaker, K., Castrechini, N., Ward, A. C., Liongue, C., Dobill, F., Kumar, J., Thompson, E. W., Quinn, M. A., Findlay, J. K. & Ahmed, N., Oct 2011, In : Journal of Cellular Biochemistry. 112, 10, p. 2850-2864 15 p.

Research output: Contribution to journalArticleResearchpeer-review

2010
160 Citations (Scopus)

Epithelial mesenchymal transition and cancer stem cell-like phenotypes facilitate chemoresistance in recurrent ovarian cancer

Ahmed, N., Abubaker, K., Findlay, J. & Quinn, M., 2010, In : Current Cancer Drug Targets. 10, 3, p. 268-278 11 p.

Research output: Contribution to journalArticleResearchpeer-review

8 Citations (Scopus)
Open Access
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2009
208 Citations (Scopus)

Cross talk of signals between EGFR and IL-6R through JAK2/STAT3 mediate epithelial-mesenchymal transition in ovarian carcinomas

Magee, M., Ward, A. C., Riley, C. B., Trenerry, M. K., Cameron-Smith, D., Findlay, J. J. K., Ackland, M. L. & Ahmed, N., 2009, In : British Journal of Cancer. 100, 1, p. 134 - 144 11 p.

Research output: Contribution to journalArticleResearchpeer-review

47 Citations (Scopus)
2005
87 Citations (Scopus)

Proteomic tracking of serum protein isoforms as screening biomarkers of ovarian cancer

Ahmed, N., Oliva, K. T., Barker, G., Hoffmann, P., Reeve, S. B., Smith, A. I., Quinn, M. A. & Rice, G. E., 2005, In : Proteomics. 5, 17, p. 4625 - 4636 12 p.

Research output: Contribution to journalArticleResearchpeer-review

2004
100 Citations (Scopus)

Proteomic-based identification of haptoglobin-1 precursor as a novel circulating biomarker of ovarian cancer

Ahmed, N., Barker, G., Oliva, K. T., Hoffmann, P., Riley, C., Reeve, S. B., Smith, A. I., Kemp, B. E., Quinn, M. A. & Rice, G. E., 2004, In : British Journal of Cancer. 91, 1, p. 129 - 140 12 p.

Research output: Contribution to journalArticleResearchpeer-review