Nitin Patil

Dr

Accepting PhD Students

PhD projects

Development of Peptide Nucleic Acids (PNAs) based antisense oligonucleotides

20132020

Research output per year

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Research Output

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Article
2020

Polymyxins Bind to the Cell Surface of Unculturable Acinetobacter baumannii and Cause Unique Dependent Resistance

Zhu, Y., Lu, J., Han, M-L., Jiang, X., Azad, M. A. K., Patil, N. A., Lin, Y-W., Zhao, J., Hu, Y., Yu, H. H., Chen, K., Boyce, J. D., Dunstan, R. A., Lithgow, T., Barlow, C. K., Li, W., Schneider-Futschik, E. K., Wang, J., Gong, B., Sommer, B. & 6 others, Creek, D. J., Fu, J., Wang, L., Schreiber, F., Velkov, T. & Li, J., 8 Jun 2020, (Accepted/In press) In : Advanced Science. 13 p., 2000704.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
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2019

Rapid Photolysis-Mediated Folding of Disulfide-Rich Peptides

Patil, N. A., Karas, J. A., Wade, J. D., Hossain, M. A. & Tailhades, J., 26 Jun 2019, In : Chemistry - A European Journal. 25, 36, p. 8599-8603 5 p.

Research output: Contribution to journalArticleResearchpeer-review

1 Citation (Scopus)

The Adsorption of Amyloidogenic Peptides to Functionalized Surfaces Is Biased by Charge and Hydrophilicity

John, T., Greene, G. W., Patil, N. A., Dealey, T. J. A., Hossain, M. A., Abel, B. & Martin, L. L., 12 Nov 2019, In : Langmuir. 35, 45, p. 14522-14531 10 p.

Research output: Contribution to journalArticleResearchpeer-review

2 Citations (Scopus)

The Kinetics of Amyloid Fibrillar Aggregation of Uperin 3.5 Is Directed by the Peptide's Secondary Structure

John, T., Dealey, T. J. A., Gray, N. P., Patil, N. A., Hossain, M. A., Abel, B., Carver, J. A., Hong, Y. & Martin, L. L., 6 Aug 2019, In : Biochemistry. 58, 35, p. 3656-3668 13 p.

Research output: Contribution to journalArticleResearchpeer-review

2 Citations (Scopus)

Thiol-Cyanobenzothiazole Ligation for the Efficient Preparation of Peptide-PNA Conjugates

Patil, N. A., Karas, J. A., Turner, B. J. & Shabanpoor, F., 20 Mar 2019, In : Bioconjugate Chemistry. 30, 3, p. 793-799 7 p.

Research output: Contribution to journalArticleResearchpeer-review

2 Citations (Scopus)
2018

Amyloid aggregation and membrane activity of the antimicrobial peptide uperin 3.5

Martin, L. L., Kubeil, C., Piantavigna, S., Tikkoo, T., Gray, N. P., John, T., Calabrese, A. N., Liu, Y., Hong, Y., Hossain, M. A., Patil, N., Abel, B., Hoffmann, R., Bowie, J. H. & Carver, J. A., 1 May 2018, In : Peptide Science. 110, 3, 9 p., e24052.

Research output: Contribution to journalArticleResearchpeer-review

7 Citations (Scopus)
2017

Combination of valproic acid and morpholino splice-switching oligonucleotide produces improved outcomes in spinal muscular atrophy patient-derived fibroblasts

Farrelly-Rosch, A., Lau, C. L., Patil, N., Turner, B. J. & Shabanpoor, F., 1 Sep 2017, In : Neurochemistry International. 108, p. 213-221 9 p.

Research output: Contribution to journalArticleResearchpeer-review

7 Citations (Scopus)

Signal transduction pathways activated by insulin-like peptide 5 at the relaxin family peptide RXFP4 receptor

Ang, S. Y., Hutchinson, D. S., Patil, N., Evans, B. A., Bathgate, R. A. D., Halls, M. L., Hossain, M. A., Summers, R. J. & Kocan, M., 1 May 2017, In : British Journal of Pharmacology. 174, 10, p. 1077-1089 13 p.

Research output: Contribution to journalArticleResearchpeer-review

15 Citations (Scopus)

The actions of relaxin family peptides on signal transduction pathways activated by the relaxin family peptide receptor RXFP4

Ang, S. Y., Hutchinson, D. S., Evans, B. A., Hossain, M. A., Patil, N., Bathgate, R. A. D., Kocan, M. & Summers, R. J., Jan 2017, In : Naunyn-Schmiedeberg's Archives of Pharmacology. 390, 1, p. 105-111 7 p.

Research output: Contribution to journalArticleResearchpeer-review

4 Citations (Scopus)
2016

A One-Pot Chemically Cleavable Bis-Linker Tether Strategy for the Synthesis of Heterodimeric Peptides

Patil, N. A., Tailhades, J., Karas, J. A., Separovic, F., Wade, J. D. & Hossain, M. A., 14 Nov 2016, In : Angewandte Chemie - International Edition. 55, 47, p. 14552-14556 5 p.

Research output: Contribution to journalArticleResearchpeer-review

11 Citations (Scopus)

A single-chain derivative of the relaxin hormone is a functionally selective agonist of the G protein-coupled receptor, RXFP1

Hossain, M. A., Kocan, M., Yao, S. T., Royce, S. G., Nair, V. B., Siwek, C., Patil, N. A., Harrison, I. P., Rosengren, K. J., Selemidis, S., Summers, R. J., Wade, J. D., Bathgate, R. A. D. & Samuel, C. S., 2016, In : Chemical Science. 7, 6, p. 3805-3819 15 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
34 Citations (Scopus)

Engineering of a novel simplified human insulin-like peptide 5 agonist

Patil, N. A., Hughes, R. A., Rosengren, K. J., Kocan, M., Ang, S. Y., Tailhades, J., Separovic, F., Summers, R. J., Grosse, J., Wade, J., Bathgate, R. A. D. & Hossain, M. A., 10 Mar 2016, In : Journal of Medicinal Chemistry. 59, 5, p. 2118-2125 8 p.

Research output: Contribution to journalArticleResearchpeer-review

14 Citations (Scopus)

The complex binding mode of the peptide hormone H2 relaxin to its receptor RXFP1

Sethi, A., Bruell, S., Patil, N., Hossain, M. A., Scott, D. J., Petrie, E. J., Bathgate, R. A. D. & Gooley, P. R., 18 Apr 2016, In : Nature Communications. 7, 11 p., 11344.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
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21 Citations (Scopus)

The C-terminus of the B-chain of human insulin-like peptide 5 is critical for cognate RXFP4 receptor activity

Patil, N. A., Bathgate, R. A. D., Kocan, M., Ang, S. Y., Tailhades, J., Separovic, F., Summers, R., Grosse, J., Hughes, R. A., Wade, J. D. & Hossain, M. A., 1 Apr 2016, In : Amino Acids. 48, 4, p. 987-992 6 p.

Research output: Contribution to journalArticleResearchpeer-review

8 Citations (Scopus)

Total Chemical Synthesis of an Intra-A-Chain Cystathionine Human Insulin Analogue with Enhanced Thermal Stability

Karas, J. A., Patil, N. A., Tailhades, J., Sani, M-A., Scanlon, D. B., Forbes, B. E., Gardiner, J., Separovic, F., Wade, J. D. & Hossain, M. A., 14 Nov 2016, In : Angewandte Chemie - International Edition. 55, 47, p. 14743-14747 6 p.

Research output: Contribution to journalArticleResearchpeer-review

18 Citations (Scopus)
2015

Site of fluorescent label modifies interaction of melittin with live cells and model membranes

Jamasbi, E., Ciccotosto, G. D., Tailhades, J., Robins-Browne, R. M., Ugalde, C. L., Sharples, R. A., Patil, N., Wade, J. D., Hossain, M. A. & Separovic, F., Oct 2015, In : Biochimica et Biophysica Acta - Biomembranes. 1848, 10, p. 2031-2039 9 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
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8 Citations (Scopus)
2013

Minimum active structure of insulin-like peptide 5

Belgi, A., Bathgate, R., Kocan, M., Patil, N., Zhang, S., Tregear, G. W., Wade, J. D. & Hossain, M. A., 2013, In : Journal of Medicinal Chemistry. 56, 23, p. 9509 - 9516 8 p.

Research output: Contribution to journalArticleResearchpeer-review

18 Citations (Scopus)