Nicole De Weerd

Research output

Research output per year 1999 1999 2002 2003 2007 2011 2012 2013 2017 2018 2019 2022 2022

• 27 Article
• 3 Encyclopaedia / Dictionary Entry
• 3 Review Article
• 1 Short Survey

Research output per year

Research output per year

Search results

• 2022

  Epigenetic Activation of Plasmacytoid DCs Drives IFNAR-Dependent Therapeutic Differentiation of AML

  Salmon, J. M., Todorovski, I., Stanley, K. L., Bruedigam, C., Kearney, C. J., Martelotto, L. G., Rossello, F., Semple, T., Arnau, G. M., Zethoven, M., Bots, M., Bjelosevic, S., Cluse, L. A., Fraser, P. J., Litalien, V., Vidacs, E., McArthur, K., Matthews, A. Y., Gressier, E., De Weerd, N. A., & 15 othersLichte, J., Kelly, M. J., Hogg, S. J., Hertzog, P. J., Kats, L. M., Vervoort, S. J., De Carvalho, D. D., Scheu, S., Bedoui, S., Kile, B. T., Lane, S. W., Perkins, A. C., Wei, A. H., Dominguez, P. M. & Johnstone, R. W., Jun 2022, In: Cancer Discovery. 12, 6, p. 1560-1579 20 p.

  Research output: Contribution to journal › Article › Research › peer-review

  Open Access
  5 Citations (Scopus)

• Type I interferon antagonism of the JMJD3-IRF4 pathway modulates macrophage activation and polarization

  Ming-Chin Lee, K., Achuthan, A. A., De Souza, D. P., Lupancu, T. J., Binger, K. J., Lee, M. K. S., Xu, Y., McConville, M. J., de Weerd, N. A., Dragoljevic, D., Hertzog, P. J., Murphy, A. J., Hamilton, J. A. & Fleetwood, A. J., 19 Apr 2022, In: Cell Reports. 39, 3, 11 p., 110719.

  Research output: Contribution to journal › Article › Research › peer-review

  Open Access
  9 Citations (Scopus)
• 2019

  A structural "star" in interferon gamma signaling

  Hertzog, P. J. & de Weerd, N. A., 1 May 2019, In: Immunology and Cell Biology. 97, 5, p. 442-444 3 p.

  Research output: Contribution to journal › Article › Other › peer-review

  Open Access
  2 Citations (Scopus)
• 2018

  A proline deletion in IFNAR1 impairs IFN-signaling and underlies increased resistance to tuberculosis in humans

  Zhang, G., Deweerd, N. A., Stifter, S. A., Liu, L., Zhou, B., Wang, W., Zhou, Y., Ying, B., Hu, X., Matthews, A. Y., Ellis, M., Triccas, J. A., Hertzog, P. J., Britton, W. J., Chen, X. & Feng, C. G., 1 Dec 2018, In: Nature Communications. 9, 1, 9 p., 85.

  Research output: Contribution to journal › Article › Research › peer-review

  Open Access

  File
  34 Citations (Scopus)

• Defining the distinct, intrinsic properties of the novel type i interferon, IFNϵ

  Stifter, S. A., Matthews, A. Y., Mangan, N. E., Fung, K. Y., Drew, A., Tate, M. D., Soares Da Costa, T. P., Hampsey, D., Mayall, J., Hansbro, P. M., Minambres, A. G., Eid, S. G., Mak, J., Scoble, J., Lovrecz, G., DeWeerd, N. A. & Hertzog, P. J., 1 Jan 2018, In: Journal of Biological Chemistry. 293, 9, p. 3168-3179 12 p.

  Research output: Contribution to journal › Article › Research › peer-review
  23 Citations (Scopus)
• 2017

  A hot spot on interferon α/β receptor subunit 1 (IFNAR1) underpins its interaction with interferon-β and dictates signaling

  de Weerd, N. A., Matthews, A. Y., Pattie, P. R., Bourke, N. M., Lim, S. S., Vivian, J. P., Rossjohn, J. & Hertzog, P. J., 5 May 2017, In: Journal of Biological Chemistry. 292, 18, p. 7554-7565 13 p.

  Research output: Contribution to journal › Article › Research › peer-review
  18 Citations (Scopus)

• Auto-phosphorylation represses protein kinase R activity

  Wang, D., De Weerd, N. A., Willard, B., Polekhina, G., Williams, B. R. G. & Sadler, A. J., 10 Mar 2017, In: Scientific Reports. 7, 15 p., 44340.

  Research output: Contribution to journal › Article › Research › peer-review

  Open Access

  File
  6 Citations (Scopus)

• Interferon epsilon promotes HIV restriction at multiple steps of viral replication

  Garcia-Minambres, A., Eid, S. G., Mangan, N. E., Pade, C., Lim, S. S., Matthews, A. Y., de Weerd, N. A., Hertzog, P. J. & Johnson, M., May 2017, In: Immunology and Cell Biology. 95, 5, p. 478-483 6 p.

  Research output: Contribution to journal › Article › Research › peer-review
  25 Citations (Scopus)
• 2014

  Purification and biological characterization of soluble, recombinant mouse IFNbeta expressed in insect cells

  Stifter, S. A., Gould, J. A., Mangan, N., Reid, H. H., Rossjohn, J., Hertzog, P. J. & De Weerd, N. A., 2014, In: Protein Expression and Purification. 94, p. 7 - 14 8 p.

  Research output: Contribution to journal › Article › Research › peer-review
  16 Citations (Scopus)
• 2013

  Interferon-epsilon protects the female reproductive tract from viral and bacterial infection

  Fung, K. Y., Mangan, N., Cumming, H. E., Horvat, J. C., Mayall, J. R., Stifter, S. A., De Weerd, N. A., Roisman, L. C., Rossjohn, J., Roberston, S. A., Schjenken, J. E., Parker, B. S., Gargett, C. E., Nguyen, H. P. T., Carr, D. J. J., Hansbro, P. M. & Hertzog, P. J., 2013, In: Science. 339, 6123, p. 1088 - 1092 5 p.

  Research output: Contribution to journal › Article › Research › peer-review
  163 Citations (Scopus)

• Structural basis of a unique interferon-beta signaling axis mediated via the receptor IFNAR1

  De Weerd, N. A., Vivian, J., Nguyen, T. K., Mangan, N., Gould, J. A., Braniff, S-J., Zaker-Tabrizi, L., Fung, K. Y., Forster, S., Beddoe, T. C., Reid, H. H., Rossjohn, J. & Hertzog, P. J., 2013, In: Nature Immunology. 14, 9, p. 901 - 907 7 p.

  Research output: Contribution to journal › Article › Research › peer-review
  205 Citations (Scopus)
• 2012

  Silencing of Irf7 pathways in breast cancer cells promotes bone metastasis through immune escape

  Bidwell, B., Slaney, C. Y., Withana, N. P., Forster, S., Cao, Y., Loi, S., Andrews, D. M., Mikeska, T., Mangan, N., Samarajiwa, S. A., De Weerd, N. A., Gould, J. A., Argani, P., Muller, A., Smyth, M., Anderson, R., Hertzog, P. J. & Parker, B., 2012, In: Nature Medicine. 18, 8, p. 1224 - 1231 8 p.

  Research output: Contribution to journal › Article › Research › peer-review
  361 Citations (Scopus)

• The interferons and their receptors--distribution and regulation

  De Weerd, N. A. & Nguyen, T. K. T., 2012, In: Immunology and Cell Biology. 90, 5, p. 483 - 491 9 p.

  Research output: Contribution to journal › Article › Research › peer-review

  Open Access

  File
  329 Citations (Scopus)
• 2011

  Suppressor of cytokine signaling (SOCS) 1 inhibits type I interferon (IFN) signaling via the interferon alpha receptor (IFNAR1)-associated tyrosine kinase Tyk2

  Piganis, R., De Weerd, N. A., Gould, J., Schindler, C., Mansell, A., Nicholson, S. & Hertzog, P., 2011, In: Journal of Biological Chemistry. 286, 39, p. 33811 - 33818 8 p.

  Research output: Contribution to journal › Article › Research › peer-review
  118 Citations (Scopus)

• Type I-IFNs control GVHD and GVL responses after transplantation

  Robb, R., Kreijveld, E., Kuns, R., Wilson, Y., Olver, S., Don, A., Raffelt, N., De Weerd, N. A., Lineburg, K., Varelias, A., Markey, K., Koyama, M., Clouston, A., Hertzog, P., MacDonald, K. & Hill, G., 2011, In: Blood. 118, 12, p. 3399 - 3409 11 p.

  Research output: Contribution to journal › Article › Research › peer-review
  61 Citations (Scopus)
• 2008

  A conserved IFN-alpha receptor tyrosine motif directs the biological response to type I IFNs

  Zhao, W., Lee, C., Piganis, R., Plumlee, C., De Weerd, N. A., Hertzog, P. J. & Schindler, C., 2008, In: Journal of Immunology. 180, 8, p. 5483 - 5489 7 p.

  Research output: Contribution to journal › Article › Research › peer-review

  39 Citations (Scopus)
• 2007

  Generation of mutant leukaemia inhibitory factor (LIF)-IgG heavy chain fusion proteins as bivalent antagonists of LIF

  Jazayeri, J., De Weerd, N. A., Raye, W. S., Velkov, T., Santos, L. L., Taylor, D. & Carroll, G. J., 2007, In: Journal of Immunological Methods. 323, 1, p. 1 - 10 10 p.

  Research output: Contribution to journal › Article › Research › peer-review

  6 Citations (Scopus)

• In vitro evaluation of leukemia inhibitory factor receptor antagonists as candidate therapeutics for inflammatory arthritis

  Jazayeri, J., De Weerd, N. A., Raye, W. S., Kivivuori, S. E., Zabihi, E. & Carroll, G. J., 2007, In: Journal of Interferon and Cytokine Research. 27, 4, p. 281 - 289 9 p.

  Research output: Contribution to journal › Article › Research › peer-review
  15 Citations (Scopus)

• Type 1 interferon receptors: Biochemistry and biological functions.

  De Weerd, N. A., Samarajiwa, S. & Hertzog, P. J., 2007, In: Journal of Biological Chemistry. 282, 28, p. 20053 - 20057 5 p.

  Research output: Contribution to journal › Article › Other
• 2004

  Molecular characterization of polygalacturonase as grass pollen-specific marker allergens: expulsion from pollen via submicronic respirable particles

  Swoboda, I., Grote, M., Verdino, P., Keller, W., Singh, M. B., De Weerd, N. A., Sperr, W. R., Valent, P., Balic, N., Reichelt, R., Suck, R., Fiebig, H., Valenta, R. & Spitzauer, S., 2004, In: Journal of Immunology. 172, p. 6490 - 6500 11 p.

  Research output: Contribution to journal › Article › Research › peer-review

  54 Citations (Scopus)
• 2003

  Effect of cysteine mutagenesis on human IgE reactivity of recombinant forms of the major rye grass pollen allergen Lol p 1

  De Weerd, N. A., Bhalla, P. L. & Singh, M. B., 2003, In: Allergology International. 52, 4, p. 183 - 190 8 p.

  Research output: Contribution to journal › Article › Research › peer-review
  10 Citations (Scopus)

• Oral immunization with a recombinant major grass pollen allergen induces blocking antibodies in mice

  De Weerd, N. A., Bhalla, P. L. & Singh, M. B., 2003, In: International Archives of Allergy and Immunology. 130, p. 119 - 124 6 p.

  Research output: Contribution to journal › Article › Research › peer-review
  11 Citations (Scopus)
• 2002

  Aeroallergens and pollinosis: Molecular and immunological characteristics of cloned pollen allergens

  De Weerd, N. A., Bhalla, P. L. & Singh, M. B., 1 Jun 2002, In: Aerobiologia. 18, 2, p. 87-106 20 p.

  Research output: Contribution to journal › Article › Research › peer-review
  30 Citations (Scopus)

• Mutants of the major ryegrass pollen allergen, Lol p 5, with reduced IgE-binding capacity:candidates for grass pollen-specific immunotherapy

  Swoboda, I., De Weerd, N. A., Bhalla, P. L., Niederberger, V., Sperr, W. R., Valent, P., Kahlert, H., Fiebig, H., Verdino, P., Keller, W., Ebner, C., Spitzauer, S., Valenta, R. & Singh, M. B., 2002, In: European Journal of Immunology. 32, p. 270 - 280 11 p.

  Research output: Contribution to journal › Article › Research › peer-review

  81 Citations (Scopus)
• 2001

  Hypoallergenic forms of the ryegrass pollen allergen Lol p5 as candidates for immunotherapy

  Swoboda, I., De Weerd, N. A., Bhalla, P. L., Niederberger, V., Sperr, W. R., Valenta, R., Kahlert, H., Fiebig, H., Verdino, P., Keller, W., Ebner, C., Spitzauer, S., Valent, P. & Singh, M. B., 2001, In: International Archives of Allergy and Immunology. 124, p. 380 - 382 3 p.

  Research output: Contribution to journal › Article › Research › peer-review
  3 Citations (Scopus)
• 1999

  Genetically engineered plant allergens with reduced anaphylatic activity

  Singh, M. B., De Weerd, N. A. & Bhalla, P. L., 1999, In: International Archives of Allergy and Immunology. 119, 2, p. 75 - 85 11 p.

  Research output: Contribution to journal › Article › Research › peer-review

• In vitro propagation of cauliflower, Brassica oleracea var. botrytis for hybrid seed production

  Bhalla, P. L. & De Weerd, N., 1 Jan 1999, In: Plant Cell, Tissue and Organ Culture. 56, 2, p. 89-95 7 p.

  Research output: Contribution to journal › Article › Research › peer-review
  23 Citations (Scopus)