Projects per year
Personal profile
Biography
Nicole is a researcher with 29 publications in total, 9 of which are first author and 3 senior author publications. Nicole has contributed to work published in a number of high impact journals including Science, Nature Immunology, Nature Medicine, Blood and Journal of Immunology. Nicole is a recipient of an NHMRC New Investigator grant (2014-2016) and a post-doctoral research fellow in the Centre for Innate Immunity and Infectious Diseases at Hudson Institute of Medical Research (formerly Monash Institute of Medical Research), Clayton. Nicole is working to elucidate structural and mechanistic characteristics of type I interferon receptor signalling, which lead to a significant publication in Nature Immunology in 2013.
Since, and including her PhD studies, the research projects that Nicole has worked on have all had a common thread, focusing on the investigation of protein-protein interactions with the view to the development of improved immunotherapeutics. Nicole has a continued interest in this field.
Community service
2012 Science in Schools Program, Kananook Primary School, Seaford, Victoria.
2013 Science in Schools Program, Kananook Primary School, Seaford, Victoria.
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
Education/Academic qualification
Biotechnology, PhD
Award Date: 31 Oct 2002
Biotechnology, Masters
Award Date: 31 Dec 1994
Research area keywords
- Type I Interferons
- Protein-Protein Interactions
- Cytokine Signaling
- Cytokne Signaling
Network
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Deciphering novel cross-talk between innate cytokine receptors
O'Keeffe, M., De Weerd, N. & Hertzog, P.
Australian Research Council (ARC)
4/06/21 → 3/06/24
Project: Research
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Evaluation of IL-6 cytokine subfamily antagonists for the treatment of inflammatory arthritis
Jazayeri, J., Carroll, G. & De Weerd, N.
1/01/04 → 31/12/05
Project: Research
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Structural integrity with functional plasticity: what type I IFN receptor polymorphisms reveal
de Weerd, N. A., Vivian, J. P., Lim, S. S., Huang, S. U-S. & Hertzog, P. J., Sep 2020, In: Journal of Leukocyte Biology. 108, 3, p. 909-924 16 p.Research output: Contribution to journal › Review Article › Research › peer-review
5 Citations (Scopus) -
A structural "star" in interferon gamma signaling
Hertzog, P. J. & de Weerd, N. A., 1 May 2019, In: Immunology and Cell Biology. 97, 5, p. 442-444 3 p.Research output: Contribution to journal › Article › Other › peer-review
Open Access1 Citation (Scopus) -
Properties and functions of the novel type I interferon epsilon
Marks, Z. R. C., Campbell, N., deWeerd, N. A., Lim, S. S., Gearing, L. J., Bourke, N. M. & Hertzog, P. J., 1 Jun 2019, In: Seminars in Immunology. 43, 9 p., 101328.Research output: Contribution to journal › Review Article › Research › peer-review
6 Citations (Scopus) -
A proline deletion in IFNAR1 impairs IFN-signaling and underlies increased resistance to tuberculosis in humans
Zhang, G., Deweerd, N. A., Stifter, S. A., Liu, L., Zhou, B., Wang, W., Zhou, Y., Ying, B., Hu, X., Matthews, A. Y., Ellis, M., Triccas, J. A., Hertzog, P. J., Britton, W. J., Chen, X. & Feng, C. G., 1 Dec 2018, In: Nature Communications. 9, 1, 9 p., 85.Research output: Contribution to journal › Article › Research › peer-review
Open AccessFile24 Citations (Scopus) -
Defining the distinct, intrinsic properties of the novel type i interferon, IFNϵ
Stifter, S. A., Matthews, A. Y., Mangan, N. E., Fung, K. Y., Drew, A., Tate, M. D., Soares Da Costa, T. P., Hampsey, D., Mayall, J., Hansbro, P. M., Minambres, A. G., Eid, S. G., Mak, J., Scoble, J., Lovrecz, G., DeWeerd, N. A. & Hertzog, P. J., 1 Jan 2018, In: Journal of Biological Chemistry. 293, 9, p. 3168-3179 12 p.Research output: Contribution to journal › Article › Research › peer-review
14 Citations (Scopus)