If you made any changes in Pure these will be visible here soon.

Personal profile

Biography

Completed Undergraduate training at Victoria University of Wellington, New Zealand. Moved to Melbourne to complete a PhD with Professor K. H. Andy Choo on DNA Methyation in Neocentromeres. Post doctoral training was in the lab of A. Prof Jeff Craig and A. Prof Richard Saffery working on DNA methylation profiling of paediatric leukaemia. Projects then led to adult tumour streams including Breast, Head and Neck and Colorectal. Took a career change and moved into commerical research and development for Pacific Edge Limited. 

Through this journey, bioinformatic skills were recognised as a valuable skill and a dialogue across disparte disciplines of biology, computer science and mathmatics converging towards bioinformatics and computational biology was mastered. 

Published over 20 peer-reviewed articles and numours book chapters in the area of Epigenetics and biomarker discovery to date. Funded previously by NHMRC as CI and the Leukaemia Foundation of Australia.

Research interests include epigenetics, DNA methylation, genomics, bioinformatics and cancer. 

Research area keywords

  • DNA Methylation
  • Bioinformatics
  • RNA-Seq
  • Next Generation Sequencing

Network Recent external collaboration on country level. Dive into details by clicking on the dots.

Projects 2019 2021

Research Output 2004 2018

2 Citations (Scopus)

A novel role for Lyl1 in primitive erythropoiesis

Chiu, S. K., Saw, J. M. Y., Huang, Y., Sonderegger, S. E., Wong, N. C. L., Powell, D. R., Beck, D., Pimanda, J., Tremblay, C. & Curtis, D. J., 11 Oct 2018, In : Development. 145, 19, 9 p., dev162990.

Research output: Contribution to journalArticleResearchpeer-review

5 Citations (Scopus)

Early-Life Formation of the Microbial and Immunological Environment of the Human Airways

Pattaroni, C., Watzenboeck, M. L., Schneidegger, S., Kieser, S., Wong, N. C., Bernasconi, E., Pernot, J., Mercier, L., Knapp, S., Nicod, L. P., Marsland, C. P., Roth-Kleiner, M. & Marsland, B. J., 12 Dec 2018, In : Cell Host and Microbe. 24, 6, p. 857-865.e4 13 p.

Research output: Contribution to journalArticleResearchpeer-review

3 Citations (Scopus)

Profiling DNA methylation differences between inbred mouse strains on the Illumina Human Infinium MethylationEPIC microarray

Gujar, H., Liang, J. W., Wong, N. C. & Mozhui, K., 1 Mar 2018, In : PLoS ONE. 13, 3, 18 p., 0193496.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
File
2 Citations (Scopus)

Restricted cell cycle is essential for clonal evolution and therapeutic resistance of pre-leukemic stem cells

Tremblay, C., Saw, J., Chiu, S. K., Wong, N. C., Tsyganov, K., Ghotb, S., Graham, A. N., Yan, F., Guirguis, A., Sonderegger, S., Lee, N., Kalitsis, P., Reynolds, J., Ting, S., Powell, D., Jane, S. & Curtis, D., 1 Dec 2018, In : Nature Communications. 9, 1, 13 p., 3535.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
File
5 Citations (Scopus)

The evolutionary pattern of mutations in glioblastoma reveals therapy-mediated selection

Muscat, A. M., Wong, N. C., Drummond, K. J., Algar, E. M., Khasraw, M., Verhaak, R., Field, K., Rosenthal, M. A. & Ashley, D. M., 1 Jan 2018, In : Oncotarget. 9, 8, p. 7844-7858 15 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
File