Research output per year
Research output per year
Personal profile
Research interests
Nicholas is a synthetic organic chemist who’s work focuses on the design and synthesis of molecules that have applications within the areas of drug discovery and life sciences.
Research area keywords
- Organic chemistry
- Peptide Chemistry
- Medicinal Chemistry
- Structure-Based Drug Design
- Fragment Based Drug Design
- Drug Delivery
- Hit-to-lead
Network
Recent external collaboration on country level. Dive into details by clicking on the dots or
Research output
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Improving Membrane Permeation in the Beyond Rule-of-Five Space by Using Prodrugs to Mask Hydrogen Bond Donors
Barlow, N., Chalmers, D. K., Williams-Noonan, B. J., Thompson, P. E. & Norton, R. S., 21 Aug 2020, In : ACS Chemical Biology. 15, 8, p. 2070-2078 9 p.Research output: Contribution to journal › Article › Research › peer-review
1 Citation (Scopus) -
IRAP Inhibitors: M1-Aminopeptidase Family Inspiration
Barlow, N. & Thompson, P. E., 25 Sep 2020, In : Frontiers in Pharmacology. 11, 8 p., 585930.Research output: Contribution to journal › Review Article › Research › peer-review
Open Access -
Macrocyclic peptidomimetics as inhibitors of insulin-regulated aminopeptidase (IRAP)
Barlow, N., Vanga, S. R., Sävmarker, J., Sandström, A., Burns, P., Hallberg, A., Åqvist, J., Gutiérrez-De-Terán, H., Hallberg, M., Larhed, M., Chai, S. Y. & Thompson, P. E., Feb 2020, In : RSC Medicinal Chemistry. 11, 2, p. 234-244 11 p.Research output: Contribution to journal › Article › Research › peer-review
5 Citations (Scopus) -
8-Mercaptoguanine Derivatives as Inhibitors of Dihydropteroate Synthase
Dennis, M. L., Lee, M. D., Harjani, J. R., Ahmed, M., Debono, A. J., Pitcher, N. P., Wang, Z-C., Chhabra, S., Barlow, N., Rahmani, R., Cleary, B., Dolezal, O., Hattarki, M., Aurelio, L., Shonberg, J., Graham, B., Peat, T. S., Baell, J. B. & Swarbrick, J. D., 6 Feb 2018, In : Chemistry - A European Journal. 24, 8, p. 1922-1930 9 p.Research output: Contribution to journal › Article › Research › peer-review
7 Citations (Scopus) -
A Cyclic Peptide Inhibitor of the iNOS-SPSB Protein-Protein Interaction as a Potential Anti-Infective Agent
Sadek, M. M., Barlow, N., Leung, E. W. W., Williams-Noonan, B. J., Yap, B. K., Shariff, F. M., Caradoc-Davies, T. T., Nicholson, S. E., Chalmers, D. K., Thompson, P. E., Law, R. H. P. & Norton, R. S., 19 Oct 2018, In : ACS Chemical Biology. 13, 10, p. 2930-2938 9 p.Research output: Contribution to journal › Article › Research › peer-review
7 Citations (Scopus)