20032021

Research output per year

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Personal profile

Biography

Prof. Huntington is the head of the Cancer Immunotherapy Laboratory at the Biomedicine Discovery Institute at Monash University, Australia. He is an international leader on natural killer (NK) cell biology with notable contributions to: regulatory mechanisms of IL-15 signalling in NK cells, identification of human and murine NK cell differentiation pathways, novel xenograft models to study human haematopoiesis and identification of multiple checkpoint in NK cell activation and tumour immunity. Prof. Huntington leads a research program aimed at deciphering the regulatory networks that control NK cell immunity and a drug discovery program using cutting-edge in vivo screens for novel checkpoints in NK cell activation for targeting in cancer immunotherapy. Prof. Huntington is President of MIN (Melbourne Immunotherapy Network), serves as project director for several pharmaceutical collaborative research programs at The Walter and Eliza Hall Institute and is a co-founder and chief scientific officer of oNKo-Innate Pty Ltd

Education/Academic qualification

PhD, University of Melbourne

20022006

External positions

Laboratory Head (Level D), Walter and Eliza Hall Institute of Medical Research (WEHI)

20172018

Honorary Fellow (Level C), University of Melbourne

20132017

Laboratory Head (Level C), Walter and Eliza Hall Institute of Medical Research (WEHI)

20132017

Senior Research Fellow (Level B), Walter and Eliza Hall Institute of Medical Research (WEHI)

20112012

Human Frontiers Long-Term Fellow, Institut Pasteur (Pasteur Institute)

20082011

RG Menzies Scholar & CJ Martin Fellow, Institut Pasteur (Pasteur Institute)

20072012

CCV Sydney Parker Smith Postdoctoral Cancer Research Fellow, Walter and Eliza Hall Institute of Medical Research (WEHI)

20062007

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Projects

Research Output

Correction: NK cell-derived GM-CSF potentiates inflammatory arthritis and is negatively regulated by CIS

Louis, C., Souza-Fonseca-Guimaraes, F., Yang, Y., D'Silva, D., Kratina, T., Dagley, L., Hediyeh-Zadeh, S., Rautela, J., Masters, S. L., Davis, M. J., Babon, J. J., Ciric, B., Vivier, E., Alexander, W. S., Huntington, N. D. & Wicks, I. P., 4 May 2020, In : Journal of Experimental Medicine. 217, 5, 1 p.

Research output: Contribution to journalArticleOtherpeer-review

Open Access
File

Crosstalk Between Gut Microbiota and Innate Immunity and Its Implication in Autoimmune Diseases

Jiao, Y., Wu, L., Huntington, N. D. & Zhang, X., 21 Feb 2020, In : Frontiers in Immunology. 11, 15 p., 282.

Research output: Contribution to journalReview ArticleResearchpeer-review

Open Access
File

Hhex regulates murine lymphoid progenitor survival independently of Stat5 and Cdkn2a

Jackson, J. T., O'Donnell, K., Light, A., Goh, W., Huntington, N. D., Tarlinton, D. M. & McCormack, M. P., 23 Feb 2020, (Accepted/In press) In : European Journal of Immunology. 13 p.

Research output: Contribution to journalArticleResearchpeer-review

miR17~92 restrains pro-apoptotic BIM to ensure survival of haematopoietic stem and progenitor cells

Brinkmann, K., Ng, A. P., de Graaf, C. A., Di Rago, L., Hyland, C. D., Morelli, E., Rautela, J., Huntington, N. D., Strasser, A., Alexander, W. S. & Herold, M. J., May 2020, In : Cell Death and Differentiation. 27, 5, p. 1475-1488 14 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
File

NK cell–derived GM-CSF potentiates inflammatory arthritis and is negatively regulated by CIS

Louis, C., Souza-Fonseca-Guimaraes, F., Yang, Y., D'Silva, D., Kratina, T., Dagley, L., Hediyeh-Zadeh, S., Rautela, J., Masters, S. L., Davis, M. J., Babon, J. J., Ciric, B., Vivier, E., Alexander, W. S., Huntington, N. D. & Wicks, I. P., 4 May 2020, In : Journal of Experimental Medicine. 217, 5, 19 p., e20191421.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
File
1 Citation (Scopus)