Projects per year
Personal profile
Biography
Prof. Huntington is the head of the Cancer Immunotherapy Laboratory at the Biomedicine Discovery Institute at Monash University, Australia. He is an international leader on natural killer (NK) cell biology with notable contributions to: regulatory mechanisms of IL-15 signalling in NK cells, identification of human and murine NK cell differentiation pathways, novel xenograft models to study human haematopoiesis and identification of multiple checkpoint in NK cell activation and tumour immunity. Prof. Huntington leads a research program aimed at deciphering the regulatory networks that control NK cell immunity and a drug discovery program using cutting-edge in vivo screens for novel checkpoints in NK cell activation for targeting in cancer immunotherapy. Prof. Huntington is President of MIN (Melbourne Immunotherapy Network), serves as project director for several pharmaceutical collaborative research programs at The Walter and Eliza Hall Institute and is a co-founder and chief scientific officer of oNKo-Innate Pty Ltd
Education/Academic qualification
PhD, University of Melbourne
2002 → 2006
External positions
Laboratory Head (Level D), Walter and Eliza Hall Institute of Medical Research (WEHI)
2017 → 2018Honorary Fellow (Level C), University of Melbourne
2013 → 2017Laboratory Head (Level C), Walter and Eliza Hall Institute of Medical Research (WEHI)
2013 → 2017Senior Research Fellow (Level B), Walter and Eliza Hall Institute of Medical Research (WEHI)
2011 → 2012Human Frontiers Long-Term Fellow, Institut Pasteur (Pasteur Institute)
2008 → 2011RG Menzies Scholar & CJ Martin Fellow, Institut Pasteur (Pasteur Institute)
2007 → 2012CCV Sydney Parker Smith Postdoctoral Cancer Research Fellow, Walter and Eliza Hall Institute of Medical Research (WEHI)
2006 → 2007
Network
Recent external collaboration on country level. Dive into details by clicking on the dots.
Projects
Next Generation Cell Therapies for Cancer
Tiganis, T., Huntington, N., Darcy, P., Zhang, Z., Cursons, J. & Vivier, E.
1/12/19 → 31/12/23
Project: Research
Identification of CIS as a potent checkpoint in NK cell-mediated tumour immunity
Huntington, N., Smyth, M. J., Vivier, E. & Nicholson, S. E.
National Health & Medical Research Council (NHMRC)
1/06/19 → 31/12/20
Project: Research
Inhibiting Bcl-2 and NK cells improves stem cell transplant outcomes in Acute Myeloid Leukaemia
Ritchie, D. S. & Huntington, N.
29/01/19 → 31/12/20
Project: Research
Harnessing the innate immune response to treat small cell lung cancer
Sutherland, K., Huntington, N. & Steinfort, D. P.
National Health & Medical Research Council (NHMRC)
1/01/19 → 31/12/22
Project: Research
Research Output
Correction: NK cell-derived GM-CSF potentiates inflammatory arthritis and is negatively regulated by CIS
Louis, C., Souza-Fonseca-Guimaraes, F., Yang, Y., D'Silva, D., Kratina, T., Dagley, L., Hediyeh-Zadeh, S., Rautela, J., Masters, S. L., Davis, M. J., Babon, J. J., Ciric, B., Vivier, E., Alexander, W. S., Huntington, N. D. & Wicks, I. P., 4 May 2020, In : Journal of Experimental Medicine. 217, 5, 1 p.Research output: Contribution to journal › Article › Other › peer-review
Open Access
File
Crosstalk Between Gut Microbiota and Innate Immunity and Its Implication in Autoimmune Diseases
Jiao, Y., Wu, L., Huntington, N. D. & Zhang, X., 21 Feb 2020, In : Frontiers in Immunology. 11, 15 p., 282.Research output: Contribution to journal › Review Article › Research › peer-review
Open Access
File
Hhex regulates murine lymphoid progenitor survival independently of Stat5 and Cdkn2a
Jackson, J. T., O'Donnell, K., Light, A., Goh, W., Huntington, N. D., Tarlinton, D. M. & McCormack, M. P., 23 Feb 2020, (Accepted/In press) In : European Journal of Immunology. 13 p.Research output: Contribution to journal › Article › Research › peer-review
miR17~92 restrains pro-apoptotic BIM to ensure survival of haematopoietic stem and progenitor cells
Brinkmann, K., Ng, A. P., de Graaf, C. A., Di Rago, L., Hyland, C. D., Morelli, E., Rautela, J., Huntington, N. D., Strasser, A., Alexander, W. S. & Herold, M. J., May 2020, In : Cell Death and Differentiation. 27, 5, p. 1475-1488 14 p.Research output: Contribution to journal › Article › Research › peer-review
Open Access
File
NK cell–derived GM-CSF potentiates inflammatory arthritis and is negatively regulated by CIS
Louis, C., Souza-Fonseca-Guimaraes, F., Yang, Y., D'Silva, D., Kratina, T., Dagley, L., Hediyeh-Zadeh, S., Rautela, J., Masters, S. L., Davis, M. J., Babon, J. J., Ciric, B., Vivier, E., Alexander, W. S., Huntington, N. D. & Wicks, I. P., 4 May 2020, In : Journal of Experimental Medicine. 217, 5, 19 p., e20191421.Research output: Contribution to journal › Article › Research › peer-review
Open Access
File
1
Citation
(Scopus)
Prizes
11th Meeting of the Society for Natural Immunity Travel Scholarship
Huntington, Nicholas (Recipient), 2008
Prize: Other distinction
1st High Commendation for the Victorian Premier’s Award
Huntington, Nicholas (Recipient), 2006
Prize: Prize (including medals and awards)
2012 Travel Award for Society of Natural Immunity 2012 Meeting
Huntington, Nicholas (Recipient), 2012
Prize: Prize (including medals and awards)
Australian Museum Eureka Prize Finalist - UNSW Prize for Scientific Research
Huntington, Nicholas (Recipient), 2016
Prize: Prize (including medals and awards)
Cancer Council Victoria Postdoctoral Fellowship
Huntington, Nicholas (Recipient), 2006
Prize: Competitive Fellowships