Projects per year
Personal profile
Biography
Professor Nellie Georgiou-Karistianis is the Pro-Vice Chancellor (Research Training) within the Deputy Vice-Chancellor (Research) portfolio. In this role she is responsible for leading and shaping the graduate research training agenda at Monash University, with a focus on implementing the broader University strategy.
Prior to this, Professor Georgiou-Karistianis was the Associate Dean (Graduate Affairs, 2015-2018) and then Deputy Dean (Academic and Graduate Affairs, 2019-2021) within the Faculty of Medicine, Nursing and Health Science at Monash University. In these roles she was responsible for overseeing academic performance across the areas of probation, performance development and promotion, as well as leading and implementing the Faculty’s graduate research strategy.
Professor Georgiou-Karistianis has a Bachelor of Science (Honours) and was awarded a Doctor of Philosophy in 1997. She heads the Georgiou-Karistianis Experimental Neuropsychology Research Unit within the Turner Institute of Brain and Mental Health. She is internationally renowned for her pioneering work in Huntington’s disease (HD) and Friedreich ataxia (FA), and has discovered novel biomarkers for tracking disease progression now being used in early drug development to inform clinical trials. Her work has provided new insights paving the way in how we examine and treat these diseases at the brain, cognitive and motor levels.
Professor Georgiou-Karistianis has led large interdisciplinary clinical programs (IMAGE-HD and IMAGE-FRDA), attracting over $16m in research funding from competitive government granting schemes (NHMRC, ARC Linkage) and philanthropic bodies. As Overall Coordinating Principal Investigator, she leads TRACK-FA – an international study comprising seven academic partners and six industry sponsors (the Friedreich’s Ataxia Research Alliance (FARA, USA), PTC Therapeutics, Takeda, IXICO, Novartis Gene Therapies, Larimar Therapeutics) across four continents (Australia, Europe, North America, South America) with a focus on validating neuroimaging biomarkers so that they’re ready to be pushed through the drug development pipeline. In this role she is also Chairperson of the TRACK-FA Neuroimaging Consortium.
She has published >230 peer-reviewed scientific papers (10 average per year), >10,500 citations, H-index 57 (Google Scholar), supervised 29 doctoral students to completion, with seven awarded NHMRC ECR Fellowships and one a Fulbright Fellowship. She has had numerous invited keynote addresses at leading international conferences, including the World Congress of Huntington’s Disease; Cure Huntington’s Disease Initiative (CHDI) Foundation Annual Therapeutics Conference; and European Huntington’s Disease Network. She is the Director of the Huntington’s Research Group of Victoria (HRGV) and is a member of the editorial board for the Journal of Huntington's Disease. She currently serves on a number of international committees, including with the Huntington’s Disease Regulatory Science Consortium (HD-RSC), Critical Path Institute and the Cure Huntington’s Disease Initiative (CHDI, USA) Foundation.
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
Education/Academic qualification
Bachelor of Science (Honours), MONASH UNIVERSITY
Doctor of Philosophy, MONASH UNIVERSITY
Leadership for Senior Executives, Harvard University
Williamson Community Leadership, Leadership Victoria
Research area keywords
- Cognitive Function
- Friedreich Ataxia
- Huntington Disease
- Motor Function
- Neurodegenerative disorders
- Neuroimaging
- Exercise training
- Cognitive neuroscience
- Dementia
- Cognitive brain training
Collaborations and top research areas from the last five years
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Deriving Functional MRI Equivalent Biomarkers in Friedreich Ataxia Solely Using Brain Structure Data
Saha, S. (Primary Chief Investigator (PCI)), Cao, T. (Chief Investigator (CI)), Naeije, G. (Chief Investigator (CI)), Noman, F. (Chief Investigator (CI)), Karistianis, N. (Chief Investigator (CI)) & Fornito, A. (Chief Investigator (CI))
Friedreich's Ataxia Research Alliance (United States of America)
1/09/24 → 31/08/25
Project: Research
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A natural history study to TRACK brain and spinal cord changes in individuals with Friedreich Ataxia (TRACK-FA)
Karistianis, N. (Primary Chief Investigator (PCI))
Friedreich's Ataxia Research Alliance (United States of America)
8/12/20 → 30/11/26
Project: Research
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A Prospective Registry Study in a Global Huntington's Disease Cohort (Enroll-HD)
10/06/13 → 8/07/28
Project: Research
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INT - 1220 Image Classification of Corrosion Cladding
Ghofrani-Jahromi, M. (Primary Chief Investigator (PCI)) & Karistianis, N. (Supervisor)
26/06/23 → 26/10/23
Project: Research
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Computerised cognitive training in Huntington’s disease
Huynh, K. (Primary Chief Investigator (PCI)), Karistianis, N. (Supervisor), Lampit, A. (Supervisor) & Jamadar, S. (Supervisor)
1/05/22 → 30/04/23
Project: Research
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Computerized Cognitive Training Increases Gray Matter Volumes in Huntington's Disease: A Pilot Study
Huynh, K., Georgiou-Karistianis, N., Lampit, A., Siddiqui, M. N., Stout, J. C. & Jamadar, S. D., Nov 2024, In: Movement Disorders. 39, 11, p. 2119-2121 4 p.Research output: Contribution to journal › Letter › Other › peer-review
Open Access2 Citations (Scopus) -
Gradient of microstructural damage along the dentato-thalamo-cortical tract in Friedreich ataxia
Cocozza, S., Bosticardo, S., Battocchio, M., Corben, L., Delatycki, M., Egan, G., Georgiou-Karistianis, N., Monti, S., Palma, G., Pane, C., Saccà, F., Schiavi, S., Selvadurai, L., Tranfa, M., Daducci, A., Brunetti, A. & Harding, I. H., Jul 2024, In: Annals of Clinical and Translational Neurology. 11, 7, p. 1691-1702 12 p.Research output: Contribution to journal › Article › Research › peer-review
Open Access1 Citation (Scopus) -
Localized Changes in Dentate Nucleus Shape and Magnetic Susceptibility in Friedreich Ataxia
Harding, I. H., Nur Karim, M. I., Selvadurai, L. P., Corben, L. A., Delatycki, M. B., Monti, S., Saccà, F., Georgiou-Karistianis, N., Cocozza, S. & Egan, G. F., Jul 2024, In: Movement Disorders. 39, 7, p. 1109-1118 10 p.Research output: Contribution to journal › Article › Research › peer-review
Open Access2 Citations (Scopus) -
Prognostic enrichment for early-stage Huntington's disease: An explainable machine learning approach for clinical trial
Ghofrani-Jahromi, M., Poudel, G. R., Razi, A., Abeyasinghe, P. M., Paulsen, J. S., Tabrizi, S. J., Saha, S. & Georgiou-Karistianis, N., Jan 2024, In: NeuroImage: Clinical. 43, 11 p., 103650.Research output: Contribution to journal › Article › Research › peer-review
Open Access2 Citations (Scopus) -
Cognition-oriented treatments and physical exercise on cognitive function in Huntington’s disease: a systematic review
Huynh, K., Nategh, L., Jamadar, S., Stout, J., Georgiou-Karistianis, N. & Lampit, A., Apr 2023, In: Journal of Neurology. 270, 4, p. 1857-1879 23 p.Research output: Contribution to journal › Review Article › Research › peer-review
9 Citations (Scopus)
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Journal of Huntington's Disease (Journal)
Nellie Georgiou-Karistianis (Editor in chief)
2017 → …Activity: Publication peer-review and editorial work types › Editorial responsibility
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Recent Patents on Biomarkers (Journal)
Nellie Georgiou-Karistianis (Editor in chief)
2017 → …Activity: Publication peer-review and editorial work types › Editorial responsibility
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NHMRC Project Grants Peer Review (Event)
Nellie Georgiou-Karistianis (Editor in chief)
2004 → 2017Activity: Publication peer-review and editorial work types › Peer review responsibility
Press/Media
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By tracking postgraduate careers, we can build on data with destiny
11/10/17
1 Media contribution
Press/Media: Public Engagement Activities
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