Projects per year
Personal profile
Biography
Professor Nellie Georgiou-Karistianis is the Pro-Vice Chancellor (Research Training) within the Deputy Vice-Chancellor (Research) portfolio. In this role she is responsible for leading and shaping the graduate research training agenda at Monash University, with a focus on implementing the broader University strategy.
Prior to this, Professor Georgiou-Karistianis was the Associate Dean (Graduate Affairs, 2015-2018) and then Deputy Dean (Academic and Graduate Affairs, 2019-2021) within the Faculty of Medicine, Nursing and Health Science at Monash University. In these roles she was responsible for overseeing academic performance across the areas of probation, performance development and promotion, as well as leading and implementing the Faculty’s graduate research strategy.
Professor Georgiou-Karistianis has a Bachelor of Science (Honours) and was awarded a Doctor of Philosophy in 1997. She heads the Georgiou-Karistianis Experimental Neuropsychology Research Unit within the Turner Institute of Brain and Mental Health. She is internationally renowned for her pioneering work in Huntington’s disease (HD) and Friedreich ataxia (FA), and has discovered novel biomarkers for tracking disease progression now being used in early drug development to inform clinical trials. Her work has provided new insights paving the way in how we examine and treat these diseases at the brain, cognitive and motor levels.
Professor Georgiou-Karistianis has led large interdisciplinary clinical programs (IMAGE-HD and IMAGE-FRDA), attracting over $16m in research funding from competitive government granting schemes (NHMRC, ARC Linkage) and philanthropic bodies. As Overall Coordinating Principal Investigator, she leads TRACK-FA – an international study comprising six academic partners and five industry sponsors (PTC Therapeutics, Takeda, IXICO, Novartis Gene Therapies) across four continents (Australia, Europe, USA, South America) with a focus on validating neuroimaging biomarkers so that they’re ready to be pushed through the drug development pipeline. In this role she is also Chairperson of the TRACK-FA Neuroimaging Consortium.
She has published >210 peer-reviewed scientific papers (10 average per year), >8,700 citations, H-index 51 (google scholar), supervised 29 doctoral students to completion, with seven awarded NHMRC ECR Fellowships and one a Fulbright Fellowship. She has had numerous invited keynote addresses at leading international conferences, including the World Congress of Huntington’s Disease; Cure Huntington’s Disease Initiative (CHDI) Foundation Annual Therapeutics Conference; and European Huntington’s Disease Network. She is the Director of the Huntington’s Research Group of Victoria (HRGV) and is a member of the editorial board for the Journal of Huntington's Disease. She currently serves on a number of international committees, including with the Huntington’s Disease Regulatory Science Consortium (HD-RSC), Critical Path Institute and the Cure Huntington’s Disease Initiative (CHDI, USA) Foundation and is a current board member on the Board of Directors of Health Education Australia Limited (HEAL).
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
Education/Academic qualification
Bachelor of Science (Honours), MONASH UNIVERSITY
Doctor of Philosophy, MONASH UNIVERSITY
Leadership for Senior Executives, Harvard University
Williamson Community Leadership, Leadership Victoria
Research area keywords
- Cognitive Function
- Friedreich Ataxia
- Huntington Disease
- Motor Function
- Neurodegenerative disorders
- Neuroimaging
- Exercise training
- Cognitive neuroscience
- Dementia
- Cognitive brain training
Network
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A Prospective Registry Study in a Global Huntington's Disease Cohort (Enroll-HD)
Stout, J. & Georgiou-Karistianis, N.
10/06/13 → 8/07/28
Project: Research
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Computerised cognitive training in Huntington’s disease
Huynh, K., Georgiou-Karistianis, N., Lampit, A. & Jamadar, S.
1/05/22 → 30/04/23
Project: Research
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A natural history study to TRACK brain and spinal changes in individuals with Friedreich Ataxia
Georgiou-Karistianis, N., Corben, L., Harding, I. & Delatycki, M.
Friedreich's Ataxia Research Alliance (United States of America)
1/11/19 → 31/01/21
Project: Research
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Neuroinflammation in Friedreich Ataxia: Mechanism, Biomarker, and Therapeutic Target
Harding, I., Egan, G., Delatycki, M., Corben, L. & Georgiou-Karistianis, N.
1/11/18 → 31/10/20
Project: Research
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Cognition-oriented treatments and physical exercise on cognitive function in Huntington’s disease: a systematic review
Huynh, K., Nategh, L., Jamadar, S., Stout, J., Georgiou-Karistianis, N. & Lampit, A., Apr 2023, In: Journal of Neurology. 270, 4, p. 1857-1879 23 p.Research output: Contribution to journal › Review Article › Research › peer-review
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Progressive Spinal Cord Degeneration in Friedreich's Ataxia: Results from ENIGMA-Ataxia
Rezende, T. J. R., Adanyeguh, I. M., Arrigoni, F., Bender, B., Cendes, F., Corben, L. A., Deistung, A., Delatycki, M., Dogan, I., Egan, G. F., Göricke, S. L., Georgiou-Karistianis, N., Henry, P-G., Hutter, D., Jahanshad, N., Joers, J. M., Lenglet, C., Lindig, T., Martinez, A. R. M., Martinuzzi, A., & 12 others , Jan 2023, In: Movement Disorders. 45, 56, p. 45-56 12 p.Research output: Contribution to journal › Article › Research › peer-review
Open Access1 Citation (Scopus) -
A natural history study to track brain and spinal cord changes in individuals with Friedreich's ataxia: TRACK-FA study protocol
Georgiou-Karistianis, N., Corben, L. A., Reetz, K., Adanyeguh, I. M., Corti, M., Deelchand, D. K., Delatycki, M. B., Dogan, I., Evans, R., Farmer, J., França, M. C., Gaetz, W., Harding, I. H., Harris, K. S., Hersch, S., Joules, R., Joers, J. J., Krishnan, M. L., Lax, M., Lock, E. F., & 17 others , 2022, In: PLoS ONE. 17, 11, 21 p., e0269649.Research output: Contribution to journal › Article › Other › peer-review
Open Access1 Citation (Scopus) -
Cognition-oriented treatments and physical exercise on cognitive function in Huntington’s disease: protocol for systematic review
Huynh, K., Nategh, L., Jamadar, S., Georgiou-Karistianis, N. & Lampit, A., Mar 2022, In: Physical Therapy Reviews. 27, 2, p. 89-94 6 p.Research output: Contribution to journal › Article › Other › peer-review
2 Citations (Scopus) -
Investigating longitudinal changes to frontal cortico-striatal tracts in Huntington’s disease: the IMAGE-HD study
Tan, B., Shishegar, R., Oldham, S., Fornito, A., Poudel, G. & Georgiou-Karistianis, N., Dec 2022, In: Brain Imaging and Behavior. 16, p. 2457–2466 10 p.Research output: Contribution to journal › Article › Research › peer-review
Open Access
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Journal of Huntington's Disease (Journal)
Nellie Georgiou-Karistianis (Editor in chief)
2017 → …Activity: Publication peer-review and editorial work types › Editorial responsibility
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Recent Patents on Biomarkers (Journal)
Nellie Georgiou-Karistianis (Editor in chief)
2017 → …Activity: Publication peer-review and editorial work types › Editorial responsibility
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NHMRC Project Grants Peer Review (Event)
Nellie Georgiou-Karistianis (Editor in chief)
2004 → 2017Activity: Publication peer-review and editorial work types › Peer review responsibility
Press/Media
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By tracking postgraduate careers, we can build on data with destiny
11/10/17
1 Media contribution
Press/Media: Public Engagement Activities
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