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Research Output 2010 2019

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2019

A 30 kDa polyethylene glycol-enfuvirtide complex enhances the exposure of enfuvirtide in lymphatic viral reservoirs in rats

Kaminskas, L. M., Williams, C. C., Leong, N. J., Chan, L. J., Butcher, N. J., Feeney, O. M., Porter, C. J. H., Tyssen, D., Tachedjian, G. & Ascher, D. B., 1 Apr 2019, In : European Journal of Pharmaceutics and Biopharmaceutics. 137, p. 218-226 9 p.

Research output: Contribution to journalArticleResearchpeer-review

2018

Doxorubicin Conjugation and Drug Linker Chemistry Alter the Intravenous and Pulmonary Pharmacokinetics of a PEGylated Generation 4 Polylysine Dendrimer in Rats

Leong, N. J., Mehta, D., McLeod, V. M., Kelly, B. D., Pathak, R., Owen, D. J., Porter, C. J. H. & Kaminskas, L. M., 1 Sep 2018, In : Journal of Pharmaceutical Sciences. 107, 9, p. 2509-2513 5 p.

Research output: Contribution to journalArticleResearchpeer-review

Reducing Dendrimer Generation and PEG Chain Length Increases Drug Release and Promotes Anticancer Activity of PEGylated Polylysine Dendrimers Conjugated with Doxorubicin via a Cathepsin-Cleavable Peptide Linker

Mehta, D., Leong, N., McLeod, V. M., Kelly, B. D., Pathak, R., Owen, D. J., Porter, C. J. H. & Kaminskas, L. M., 1 Oct 2018, In : Molecular Pharmaceutics. 15, 10, p. 4568-4576 9 p.

Research output: Contribution to journalArticleResearchpeer-review

2017

An Evaluation of Optimal PEGylation Strategies for Maximizing the Lymphatic Exposure and Antiviral Activity of Interferon after Subcutaneous Administration

Chan, L. J., Feeney, O. M., Leong, N. J., McLeod, V. M., Porter, C. J. H., Williams, C. C. & Kaminskas, L. M., 11 Sep 2017, In : Biomacromolecules. 18, 9, p. 2866-2875 10 p.

Research output: Contribution to journalArticleResearchpeer-review

Microfluidic preparation of drug-loaded PEGylated liposomes, and the impact of liposome size on tumour retention and penetration

Dong, Y. D., Tchung, E., Nowell, C., Kaga, S., Leong, N., Mehta, D., Kaminskas, L. M. & Boyd, B. J., 21 Nov 2017, (Accepted/In press) In : Journal of Liposome Research. p. 1-9 9 p.

Research output: Contribution to journalArticleResearchpeer-review

The effect of intravenous sulfobutylether7-beta-cyclodextrin on the pharmacokinetics of a series of adamantane-containing compounds

Leong, N., Prankerd, R. J., Shackleford, D. & McIntosh, M. P., 2015, In : Journal of Pharmaceutical Sciences. 104, 4, p. 1492 - 1498 7 p.

Research output: Contribution to journalArticleResearchpeer-review

2010

Impact of chlorpromazine self-association on its apparent binding constants with cyclodextrins: Effect of SBE7-beta-CD on the disposition of chlorpromazine in the rat

McIntosh, M. P., Leong, N., Katneni, K., Morizzi, J., Shackleford, D. M. & Prankerd, R. J., 2010, In : Journal of Pharmaceutical Sciences. 99, 7, p. 2999 - 3008 10 p.

Research output: Contribution to journalArticleResearchpeer-review