20122019

Research output per year

If you made any changes in Pure these will be visible here soon.

Personal profile

Biography

Dr. Natasha Anstee completed her PhD in 2015 at The Walter and Eliza Hall Institute of Medical Research where she was supervised by Prof. Suzanne Cory. During her PhD, Dr. Anstee investigated the consequences of overexpression of the prosurvial protein MCL-1 for haemopoiesis, autoimmunity and for the development and treatment of MLL-AF9-induced AML. 

From 2017-2019 Dr. Anstee worked as a Postdoctoral Reseach Fellow at the German Cancer Research Centre (DKFZ) and Heidelberg Institute of Stem Cell Technology and Experimental Medicine (HI-STEM) in the laboratory of Dr. Michael Milsom. Her research was focused on reassessing the concept of haempoietic stem cell self-renewal based on single cell tranplantation outcomes.

In 2020 she joined the Leukemia Research Group, led by A/Prof. Andrew Wei at the Austrlian Centre for Blood Diseases (Monash University), based at The Alfred Hospital. She is in charge of the correlative studies emerging from AML clinical trials led by A/Prof. Wei, with a major focus on tracking MRD using NGS assays as well investigating clonal evolution through single cell technologies.

External positions

Research Scientist, Alfred Hospital

Network Recent external collaboration on country level. Dive into details by clicking on the dots.

Research Output

Platelet GPIbα is a mediator and potential interventional target for NASH and subsequent liver cancer

Malehmir, M., Pfister, D., Gallage, S., Szydlowska, M., Inverso, D., Kotsiliti, E., Leone, V., Peiseler, M., Surewaard, B. G. J., Rath, D., Ali, A., Wolf, M. J., Drescher, H., Healy, M. E., Dauch, D., Kroy, D., Krenkel, O., Kohlhepp, M., Engleitner, T., Olkus, A. & 46 others, Sijmonsma, T., Volz, J., Deppermann, C., Stegner, D., Helbling, P., Nombela-Arrieta, C., Rafiei, A., Hinterleitner, M., Rall, M., Baku, F., Borst, O., Wilson, C. L., Leslie, J., O’Connor, T., Weston, C. J., Adams, D. H., Sheriff, L., Teijeiro, A., Prinz, M., Bogeska, R., Anstee, N., Bongers, M. N., Notohamiprodjo, M., Geisler, T., Withers, D. J., Ware, J., Mann, D. A., Augustin, H. G., Vegiopoulos, A., Milsom, M. D., Rose, A. J., Lalor, P. F., Llovet, J. M., Pinyol, R., Tacke, F., Rad, R., Matter, M., Djouder, N., Kubes, P., Knolle, P. A., Unger, K., Zender, L., Nieswandt, B., Gawaz, M., Weber, A. & Heikenwalder, M., 1 Apr 2019, In : Nature Medicine. 25, 4, p. 641-655 15 p.

Research output: Contribution to journalArticleResearchpeer-review

26 Citations (Scopus)

Anti-apoptotic proteins BCL-2, MCL-1 and A1 summate collectively to maintain survival of immune cell populations both in vitro and in vivo

Carrington, E. M., Zhan, Y., Brady, J. L., Zhang, J. G., Sutherland, R. M., Anstee, N. S., Schenk, R. L., Vikstrom, I. B., Delconte, R. B., Segal, D., Huntington, N. D., Bouillet, P., Tarlinton, D. M., Huang, D. C. S., Strasser, A., Cory, S., Herold, M. J. & Lew, A. M., 1 May 2017, In : Cell Death and Differentiation. 24, 5, p. 878-888 11 p.

Research output: Contribution to journalArticleResearchpeer-review

24 Citations (Scopus)

Elevated Mcl-1 inhibits thymocyte apoptosis and alters thymic selection

Campbell, K. J., Gray, D. H. D., Anstee, N., Strasser, A. & Cory, S., 1 Dec 2012, In : Cell Death and Differentiation. 19, 12, p. 1962-1971 10 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
9 Citations (Scopus)