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PhD projects

Identification of ADAM17-driven molecular events in health and disease

20152019

Research output per year

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Personal profile

Education/Academic qualification

Molecular and Translational Sciences, PhD, MONASH UNIVERSITY

Award Date: 29 May 2019

Biochemistry, Master, Alexandria University

Award Date: 30 Sep 2014

Pharmaceutical Sciences, Bachelor, Alexandria University

Award Date: 1 Aug 2010

Research area keywords

  • Cancer
  • Cancer Biology
  • Inflammation
  • Signalling pathways
  • Cytokines
  • Lung Cancer

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Research Output

ADAM17: An emerging therapeutic target for lung cancer

Saad, M. I., Rose-John, S. & Jenkins, B. J., 21 Aug 2019, In : Cancers. 11, 9, 28 p., 1218.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
File
5 Citations (Scopus)

ADAM17 selectively activates the IL-6 trans-signaling/ERK MAPK axis in KRAS-addicted lung cancer

Saad, M. I., Alhayyani, S., McLeod, L., Yu, L., Alanazi, M., Deswaerte, V., Tang, K., Jarde, T., Smith, J. A., Prodanovic, Z., Tate, M. D., Balic, J. J., Watkins, D. N., Cain, J. E., Bozinovski, S., Algar, E., Kohmoto, T., Ebi, H., Ferlin, W., Garbers, C. & 4 others, Ruwanpura, S., Sagi, I., Rose-John, S. & Jenkins, B. J., Apr 2019, In : EMBO Molecular Medicine. 11, 4, 19 p., e9976.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
File
6 Citations (Scopus)

Serine-phosphorylated STAT3 promotes tumorigenesis via modulation of RNA polymerase transcriptional activity

Balic, J. J., Garama, D. J., Saad, M. I., Yu, L., West, A. C., West, A. J., Livis, T., Bhathal, P. S., Gough, D. J. & Jenkins, B. J., 15 Oct 2019, In : Cancer Research. 79, 20, p. 5272-5287 16 p.

Research output: Contribution to journalArticleResearchpeer-review

1 Citation (Scopus)

Amnion Epithelial Cell-Derived Exosomes Restrict Lung Injury and Enhance Endogenous Lung Repair

Tan, J. L., Lau, S. N., Leaw, B., Nguyen, H. P. T., Salamonsen, L. A., Saad, M. I., Chan, S. T., Zhu, D., Krause, M., Kim, C., Sievert, W., Wallace, E. M. & Lim, R., 1 Feb 2018, In : Stem Cells Translational Medicine. 7, 2, p. 180-196 17 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
File
31 Citations (Scopus)

Tissue processing for stereological analyses of lung structure in chronic obstructive pulmonary disease

Saad, M. & Ruwanpura, S. M., 1 Jan 2018, Inflammation and Cancer: Methods and Protocols. Jenkins, B. J. (ed.). USA: Humana Press, p. 155-162 8 p. (Methods in Molecular Biology; vol. 1725).

Research output: Chapter in Book/Report/Conference proceedingChapter (Book)Otherpeer-review

2 Citations (Scopus)