Research output per year
Research output per year
Accepting PhD Students
PhD projects
For more information and application, please visit the link in the supervision interest.
Non-coding RNAs in human gliomas (2D and 3D models) drug resistance and cell motility.
Mechanisms or standard drugs chemosensitization in cancer cells.
Natural products and adjuvant potential in cancer and gliomas.
https://supervisorconnect.med.monash.edu/projects/elucidating-synergistic-proteogenomic-anticancer-mechanisms-lentinan-shiitake-mushroom
https://supervisorconnect.med.monash.edu/projects/long-noncoding-rna-regulation-temozolomide-resistance-p53-mutant-glioblastoma
https://supervisorconnect.med.monash.edu/projects/elucidating-synergistic-mechanisms-ms17-and-chrysin-combination-human-chemoresistant
Research activity per year
Muhamad Noor Alfarizal Kamarudin is a lecturer at Jeffrey Cheah School of Medicine and Health Sciences, Monash University Malaysia. His research particular interest is to identify and develop a diagnostic and therapeutic approach to human gliomas.
He completed his Bachelor's Degree (Biochemistry, Hons) from the University of Malaya (UM). He pursued his Master's studies, which he successfully converted into a doctorate program (UM, 2012). Upon completing his Ph.D. (2016), he obtained a postdoctoral researcher position under a three-way collaboration between UM, Taibah University of Medina, and Lincoln College University on Glioblastoma before joining BRIMS, JCSMHS in October 2017.
He specializes in cancer biology, molecular biology, neuroimmunology, neuroprotection, and natural products. His Ph.D. thesis focuses on modulating molecular signaling in neuroinflammation with particular attention to cytokines and chemokines. He identified a potentially novel role of CCL21/exodus in neuronal differentiation key regulator of microglia activation. Through this, he developed an immense interest and in-depth knowledge of the modulation of neuroinflammation, particularly innate immunity in neurons and glia in neuroprotection, neuritogenesis, and anti-inflammatory.
Dr. Alfa is also the Guest Associate Editor for Frontiers in Pharmacology (Section - Ethnopharmacology) and Topic Editor for 'Natural Products for Neuroprotection and Neuroregeneration'.
Awards:
He also has won several awards during his such as the Best Thesis Award University Malaya & Amersham Biosciences Prize by the Malaysia Society of Biochemistry and Molecular Biology (MSBMB), 1st Prize Oral Presenter at InPRAS Conference UM 2014, 1st Prize Poster Presenter at World Congress on Healthy Ageing, Best Poster Presentation, 39th Annual Malaysian Society for Biochemistry and Molecular Biology Conference, and Silver Medal Winner for Poster Presentation (Biochemistry & Physiology), at Biological Sciences Graduate Congress, the National University of Singapore, 2014 (International).
Professional Membership
Dr. Alfa primary research aspiration is to develop novel therapeutic targets in human gliomas management that will tackle tumor cell motility, chemoresistant, and tumor recurrence, ultimately improving the prognosis among patients with different tumor status backgrounds. His cardinal focus is on targeting multimodal mechanistic pathways using molecules such as natural products, neuropeptides, noncoding RNAs. Additionally, his research team focuses on the alternative neuroendocrine system since gender disparity is seen in human gliomas. He envisions human gliomas management's bright future through neo-adjuvants' potentiality in improving current established therapy that enhances patients' prognoses while being cost-effective with marginal side effects would lead to more affordable treatment gliomas.
He has been involved in obtaining various research grants such as FRGS grant 2019, BRIMS-JCSMHS collaboration grants (2020), High Impact Research (HIR) UM, Fundamental Research Grant Scheme (MoHE – Best FRGS Project Award 2014), and University Malaya Research Grant (UMRG). He is also an active reviewer for several journals such as the Journal of Experimental & Clinical Cancer Research, Scientific Reports, Scientific Reports, Biomedicine & Pharmacotherapy, Frontiers in Pharmacology, Oncotarget and Therapy, Molecular and Cellular Biochemistry, Journal of Ethnopharmacology, Cancer Management and Research and Journal of Functional Food.
Areas of Interests:
Current research projects:
Internal Research Grant
External Seed Grant
Yayasan Penyelidikan Otak, Minda dan Neurosains Malaysia (YPOMN) 2021 - Identification of spexin receptors & their functionality in human glioblastoma with different Temozolomide sensitivity/RM5, 0000 (Co-Investigator). Status: Ongoing
MED 1100/1200 - PBL Year 1
MED 1100/1200 - Health, Knowledge & Society
MED 1100/1200 - Biochemistry
MED 1100/1200 - Physiology
MED 2100 & MED 2200 - Student project cases
MED5101 - Applied Studies in Medical Research and Professional Practice/Scholarly Intensive Placement (SIP)
NUT1023 - Nutritional Biochemistry & Nutrigenomics
My supervision interests in the field of:
For more information and application, please visit:
1) long noncoding RNA regulation of temozolomide resistance p53-mutant glioblastoma
2) ms17 and chrysin combination in human chemoresistant Glioblastoma
3) synergistic proteogenomic anticancer mechanisms of lentinan towards Temozolomide
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
Biochemistry: Molecular Biology & Neuroimmunology, Ph.D, Universiti Malaya (University of Malaya)
Award Date: 8 Oct 2016
Music (Teaching), Associate Diploma, International Music Examinations Board, Australia
Award Date: 31 Jan 2014
Biochemistry, Bsc, Universiti Malaya (University of Malaya)
Award Date: 15 Oct 2010
Research output: Contribution to journal › Review Article › Research › peer-review
Research output: Contribution to journal › Review Article › Research › peer-review
Research output: Contribution to journal › Review Article › Research › peer-review
Research output: Contribution to journal › Review Article › Research › peer-review
Research output: Contribution to journal › Review Article › Research › peer-review
Kamarudin, MNA (Recipient), 29 Aug 2014
Prize: Prize (including medals and awards)
Kamarudin, MNA (Recipient), 27 Jul 2010
Prize: Prize (including medals and awards)
Balasubramaniam, Vinod (Recipient), Hooi, Yuan Teng (Recipient), SyedHassan, Sharifah (Recipient), Ogawa, Satoshi (Recipient), Kamarudin, MNA (Recipient), Wong, P. K. T. (Recipient), Hariono , M. (Recipient) & Sastre , P. A. G. (Recipient), 2021
Prize: Other distinction
Kamarudin, MNA (Recipient), 11 Dec 2014
Prize: Prize (including medals and awards)
Kamarudin, MNA (Recipient), 31 Mar 2012
Prize: Prize (including medals and awards)
MNA Kamarudin (Guest editor)
Activity: Publication peer-review and editorial work types › Editorial responsibility
MNA Kamarudin (Associate editor)
Activity: Publication peer-review and editorial work types › Editorial responsibility