Projects per year
Personal profile
Biography
Dr Mitchell Lawrence is a Research Fellow in the Department of Anatomy and Developmental Biology and Biomedicine Discovery Institute, Monash University. He graduated with a PhD from Queensland University of Technology in 2009 before joining the Prostate Cancer Research Group at Monash University. His expertise includes the use of patient-derived xenografts of prostate cancer as preclinical models for studying tumour biology and testing novel therapies. His research also focusses on the tumour microenvironment of prostate cancer, particularly the features of cancer-associated fibroblasts. For these multidisciplinary studies, Dr Lawrence works with a diverse team of collaborators, including urologists, oncologists, pathologists, bioinformaticians and patient advocates.
Dr Lawrence is the recipient of funding from the National Health and Medical Research Council (Early Career Fellowship, project grants), the Victorian Government through the Victorian Cancer Agency (Early Career Seed Grant, Mid-Career Fellowship), the Prostate Cancer Foundation of Australia (Movember Young Investigator Grant) and several philanthropic organisations.
Research area keywords
- Prostate cancer
- Urology
- Endocrinology
- Tumour microenvironment
- Patient-derived models
Network
Recent external collaboration on country level. Dive into details by clicking on the dots.
Projects 2012 2023
New combination therapies for castration-resistant prostate cancer
Lawrence, M., Risbridger, G., Azad, A. & Taylor, R.
15/02/19 → 14/02/23
Project: Research
Giving prostate cancer enough rope with supraphysiologic testosterone
Lawrence, M., Risbridger, G. & Joshua, A. M.
National Health & Medical Research Council (NHMRC)
1/01/19 → 31/12/21
Project: Research
Research Output 2005 2019
Patient-derived Models of Abiraterone- and Enzalutamide-resistant Prostate Cancer Reveal Sensitivity to Ribosome-directed Therapy
Lawrence, M. G., Obinata, D., Sandhu, S., Selth, L. A., Wong, S. Q., Porter, L. H., Lister, N., Pook, D., Pezaro, C. J., Goode, D. L., Rebello, R. J., Clark, A. K., Papargiris, M., Van Gramberg, J., Hanson, A. R., Banks, P., Wang, H., Niranjan, B., Keerthikumar, S., Hedwards, S. & 32 others, , 1 Nov 2018, In : European Urology. 74, 5, p. 562-572 11 p.Research output: Contribution to journal › Article › Research › peer-review
Enduring epigenetic landmarks define the cancer microenvironment
Pidsley, R., Lawrence, M. G., Zotenko, E., Niranjan, B., Statham, A., Song, J., Chabanon, R. M., Qu, W., Wang, H., Richards, M., Nair, S. S., Armstrong, N., Nim, H. T., Papargiris, M., Balanathan, P., French, H., Peters, T., Norden, S., Ryan, A., Pedersen, J. & 9 others, , 1 May 2018, In : Genome Research. 28, 5, p. 625-638 14 p.Research output: Contribution to journal › Article › Research › peer-review
Systematic Review Links the Prevalence of Intraductal Carcinoma of the Prostate to Prostate Cancer Risk Categories
Porter, L. H., Lawrence, M. G., Ilic, D., Clouston, D., Bolton, D. M., Frydenberg, M., Murphy, D. G., Pezaro, C., Risbridger, G. P. & Taylor, R. A., Oct 2017, In : European Urology. 72, 4, p. 492-495 4 p.Research output: Contribution to journal › Article › Research › peer-review
Patient-derived Xenografts Reveal that Intraductal Carcinoma of the Prostate Is a Prominent Pathology in BRCA2 Mutation Carriers with Prostate Cancer and Correlates with Poor Prognosis
Risbridger, G. P., Taylor, R. A., Clouston, D., Sliwinski, A., Thorne, H. J., Hunter, S. M., Li, J., Mitchell, G. W. E., Murphy, D. G. M., Frydenberg, M., Pook, D. W., Pedersen, J. S., Toivanen, R., Wang, H., Papargiris, M., Lawrence, M. G. & Bolton, D. M., 1 Mar 2015, In : European Urology. 67, 3, p. 496 - 503 8 p.Research output: Contribution to journal › Article › Research › peer-review
A preclinical xenograft model of prostate cancer using human tumors
Lawrence, M. G., Taylor, R. A., Toivanen, R., Pedersen, J. S., Norden, S., Pook, D. W., Frydenberg, M., Australian Prostate Cancer BioResource, Papargiris, M., Niranjan, B., Richards, M. G., Wang, H., Collins, A. T., Maitland, N. J. & Risbridger, G. P., 2013, In : Nature Protocols. 8, 5, p. 836 - 848 13 p.Research output: Contribution to journal › Article › Research › peer-review
Prizes
Victorian Cancer Agency Mid-Career Research Fellowship
Mitchell Lawrence (Recipient), 2019
Prize: Competitive Fellowships
Science Communication and Community Engagement Award, Biomedicine Discovery Institute, Monash University
Mitchell Lawrence (Recipient), 2017
Prize: Prize (including medals and awards)
Australian Society of Medical Research Student Conference Poster Prize
Mitchell Lawrence (Recipient), 2007
Prize: Prize (including medals and awards)
Cancer Council Queensland Travel Prize
Mitchell Lawrence (Recipient), 2008
Prize: Prize (including medals and awards)
CASS Foundation Travel Award
Mitchell Lawrence (Recipient), 2014
Prize: Prize (including medals and awards)
Press / Media
Movember @ Mo-nash – Raising Awareness for Prostate Cancer Research
21/11/19
1 Media contribution
Press/Media: Blogs, Podcasts and Social Media › Podcasts