Projects per year
Personal profile
Biography
Associate Professor Mireille Lahoud heads a research group focussed on Dendritic Cell Receptors, their role in pattern recognition and their application for immune modulation.
Assoc. Prof. Lahoud completed her PhD and her early postdoctoral training at Monash University, where she focussed on identification of novel DNA binding proteins. She then applied her molecular expertise to the molecular analysis of dendritic cell (DC) subsets in Professor Shortman's team at The Walter and Eliza Hall Institute. Assoc. Prof. Lahoud's research focussed on the identification of DC-surface molecules that underpin DC function in mouse and human, and as DC targets for immune modulation. In 2012, she established a research team to focus on Dendritic Cell Receptors at Burnet Institute. In 2015, she relocated her team to Monash University. She is also an Honorary Lecturer of the Mater Resarch Institute-UQ and an Honorary Burnet Institute Senior Fellow.
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
Research area keywords
- Clec9A
- Clec12A
- Damage Associated Molecular Patterns
- Dendritic Cell Receptors
- C-type lectin like receptors
- Dendritic Cell Function
- adjuvants
- dendritic cells
- humoral immunity
- non-human primates
- vaccines
- clec9a
- cross-presentation
- dc targeting
- immunotherapy
- xcr1
Network
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The regulatory role of Clec12A in antigen presentation and inflammatory disease
Lahoud, M., Begun, J., Caminschi, I. & Shortman, K. D.
1/01/18 → 31/12/22
Project: Research
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Clec9A targeting antibodies as a new immunotherapy for prostate cancer
Radford, K. & Lahoud, M.
Project: Research
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Molecular basis for the efficient processing of antigens taken up by Clec9A, a DAMP receptor on dendritic cells
Lahoud, M., Caminschi, I. & Shortman, K. D.
National Health and Medical Research Council (NHMRC) (Australia)
1/01/15 → 31/12/19
Project: Research
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Enhancing the immunogenicity of cancer vaccines by harnessing CLEC9A
Lahoud, M. H. & Radford, K. J., 2022, In: Human Vaccines & Immunotherapeutics. 18, 1, 5 p., 1873056.Research output: Contribution to journal › Article › Other › peer-review
Open Access1 Citation (Scopus) -
The cryo-EM structure of the endocytic receptor DEC-205
Gully, B. S., Venugopal, H., Fulcher, A. J., Fu, Z., Li, J., Deuss, F. A., Llerena, C., Heath, W. R., Lahoud, M. H., Caminschi, I., Rossjohn, J. & Berry, R., 1 Jan 2021, In: Journal of Biological Chemistry. 296, 12 p., 100127.Research output: Contribution to journal › Article › Research › peer-review
Open Access1 Citation (Scopus) -
The Inhibitory Receptor CLEC12A Regulates PI3K-Akt Signaling to Inhibit Neutrophil Activation and Cytokine Release
Paré, G., Vitry, J., Merchant, M. L., Vaillancourt, M., Murru, A., Shen, Y., Elowe, S., Lahoud, M. H., Naccache, P. H., McLeish, K. R. & Fernandes, M. J., 21 Jun 2021, In: Frontiers in Immunology. 12, 15 p., 650808.Research output: Contribution to journal › Article › Research › peer-review
Open Access4 Citations (Scopus) -
A Natural Peptide Antigen within the Plasmodium Ribosomal Protein RPL6 Confers Liver TRM Cell-Mediated Immunity against Malaria in Mice
Valencia-Hernandez, A. M., Ng, W. Y., Ghazanfari, N., Ghilas, S., de Menezes, M. N., Holz, L. E., Huang, C., English, K., Naung, M., Tan, P. S., Tullett, K. M., Steiner, T. M., Enders, M. H., Beattie, L., Chua, Y. C., Jones, C. M., Cozijnsen, A., Mollard, V., Cai, Y., Bowen, D. G. & 15 others, , 10 Jun 2020, In: Cell Host & Microbe. 27, 6, p. 950-962 13 p.Research output: Contribution to journal › Article › Research › peer-review
22 Citations (Scopus) -
Display of native antigen on cDC1 that have spatial access to both T and B cells underlies efficient humoral vaccination
Kato, Y., Steiner, T. M., Park, H-Y., Hitchcock, R. O., Zaid, A., Hor, J. L., Devi, S., Davey, G. M., Vremec, D., Tullett, K. M., Tan, P. S., Ahmet, F., Mueller, S. N., Alonso, S., Tarlinton, D. M., Ploegh, H. L., Kaisho, T., Beattie, L., Manton, J. H., Fernandez-Ruiz, D. & 4 others, , 1 Oct 2020, In: Journal of Immunology. 205, 7, p. 1842-1856 15 p.Research output: Contribution to journal › Article › Research › peer-review
Open AccessFile10 Citations (Scopus)