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Personal profile

Biography

Associate Professor Mireille Lahoud heads a research group focussed on Dendritic Cell Receptors, their role in pattern recognition and their application for immune modulation. 
Assoc. Prof. Lahoud completed her PhD and her early postdoctoral training at Monash University, where she focussed on identification of novel DNA binding proteins. She then applied her molecular expertise to the molecular analysis of dendritic cell (DC) subsets in Professor Shortman's team at The Walter and Eliza Hall Institute. Assoc. Prof. Lahoud's research focussed on the identification of DC-surface molecules that underpin DC function in mouse and human, and as DC targets for immune modulation. In 2012, she established a research team to focus on Dendritic Cell Receptors at Burnet Institute. In 2015, she relocated her team to Monash University. She is also an Honorary Lecturer of the Mater Resarch Institute-UQ and an Honorary Burnet Institute Senior Fellow.

Keywords

  • Clec9A
  • Clec12A
  • Damage Associated Molecular Patterns
  • Dendritic Cell Receptors
  • C-type lectin like receptors
  • Dendritic Cell Function
  • adjuvants
  • dendritic cells
  • humoral immunity
  • non-human primates
  • vaccines
  • clec9a
  • cross-presentation
  • dc targeting
  • immunotherapy
  • xcr1

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Projects 2013 2022

Research Output 1993 2019

Classical Type 1 Dendritic Cells Dominate Priming of Th1 Responses to Herpes Simplex Virus Type 1 Skin Infection

Harpur, C. M., Kato, Y., Dewi, S. T., Stankovic, S., Johnson, D. N., Bedoui, S., Whitney, P. G., Lahoud, M. H., Caminschi, I., Heath, W. R., Brooks, A. G. & Gebhardt, T., 1 Feb 2019, In : Journal of Immunology. 202, 3, p. 653-663 11 p.

Research output: Contribution to journalArticleResearchpeer-review

Zymosan by-passes the requirement for pulmonary antigen encounter in lung tissue-resident memory CD8+ T cell development

Caminschi, I., Lahoud, M. H., Pizzolla, A. & Wakim, L. M., 21 Jan 2019, In : Mucosal Immunology. 12, p. 403-412 10 p.

Research output: Contribution to journalArticleResearchpeer-review

CD8+ T Cell Activation Leads to Constitutive Formation of Liver Tissue-Resident Memory T Cells that Seed a Large and Flexible Niche in the Liver

Holz, L. E., Prier, J. E., Freestone, D., Steiner, T. M., English, K., Johnson, D. N., Mollard, V., Cozijnsen, A., Davey, G. M., Godfrey, D. I., Yui, K., Mackay, L. K., Lahoud, M. H., Caminschi, I., McFadden, G. I., Bertolino, P., Fernandez-Ruiz, D. & Heath, W. R., 2 Oct 2018, In : Cell Reports. 25, 1, p. 68-79 13 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
File

Self-adjuvanting nanoemulsion targeting dendritic cell receptor Clec9A enables antigen-specific immunotherapy

Zeng, B., Middelberg, A. P. J., Gemiarto, A., MacDonald, K. P. A., Baxter, A. G., Talekar, M., Moi, D., Tullett, K. M., Caminschi, I., Lahoud, M. H., Mazzieri, R., Dolcetti, R. & Thomas, R., 1 May 2018, In : Journal of Clinical Investigation. 128, 5, p. 1971-1984 14 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
File

Antibody-mediated targeting of antigen to C-type lectin-like receptors Clec9A and Clec12A elicits different vaccination outcomes

Macri, C., Dumont, C., Panozza, S., Lahoud, M. H., Caminschi, I., Villadangos, J. A., Johnston, A. P. R. & Mintern, J. D., Jan 2017, In : Molecular Immunology. 81, p. 143-150 8 p.

Research output: Contribution to journalArticleResearchpeer-review