Personal profile
Biography
Dr Minni (Minna-Liisa) Änkö heads the Functional RNAomics laboratory, holding a joint appointment at the Centre of Reproductive Health and Centre for Cancer Research.
Minni obtained her PhD from the Åbo Akademi University in Finland. She was a post-doctoral fellow at the Max Planck Institute of Cell Biology and Genetics, in Dresden, Germany 2006-2011, supported by a Sigrid Juselius Foundation Post-doctoral Fellowship. Minni moved to Australia in 2011 when she received a Jane and Aatos Erkko Foundation Fellowship, and worked as a visiting scientist at the Australian Regenerative Medicine Institute, Monash University. She then continued her research as a senior research fellow at the Walter and Eliza Hall Institute (2012-2013) until establishing her independent laboratory at the Monash University in 2014 and relocating to Hudson Institute in 2018.
The Functional RNAomics laboratory investigates gene regulation via RNA processing by combining wet and dry lab approaches. The team aims to crack the RNA code of cells by investigating how RNA binding proteins tune the gene expression output in various types of stem cells, during early development and in specialised cell types. Importantly, by understanding the underlying mechanisms of RNA regulation we gain critical insights into how aberrations in the RNA machinery result in genetic disorders and cancer.
Minni is a passionate ambassador of RNA research as well as the significance of RNA regulation in human health. She is the Victorian representative for the RNAoz, a special interest group in RNA biology in Australia and convenes meRNA club, a seminar series supported by the International RNA Society.
Education/Academic qualification
Biology, PhD, Abo Akademi University
Award Date: 28 Dec 2005
Bichemistry, MSc, Turun Yliopisto (University of Turku)
Award Date: 21 Dec 1999
Research area keywords
- RNA, RNA binding proteins, gene expression, genetic disease, stem cell, differentiation
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
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SDG 3 Good Health and Well-being
Collaborations and top research areas from the last five years
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Dynamic assembly of mRNP complexes in response to differentiation and stress
Anko, M.-L. (Primary Chief Investigator (PCI)), Preiss, T. (Associate Investigator (AI)) & Straesser, K. (Chief Investigator (CI))
Monash University – Internal University Contribution
Project: Research
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Regulatory roles of the RNA helicase DDX5 in male germline stem cells
Hobbs, R. (Primary Chief Investigator (PCI)) & Anko, M.-L. (Partner Investigator (PI))
12/07/22 → 11/07/25
Project: Research
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Precursor neurons on standby fast track neural repair
Kaslin, J. (Primary Chief Investigator (PCI)), Anko, M.-L. (Chief Investigator (CI)), Vukovic, J. (Associate Investigator (AI)) & Rossello, F. (Associate Investigator (AI))
1/01/22 → 31/12/24
Project: Research
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Automatic quantitative locomotion and behaviour phenotyping setup for small animals
Kaslin, J. (Primary Chief Investigator (PCI)), Currie, P. (Chief Investigator (CI)), Ruparelia, A. (Chief Investigator (CI)), Pocock, R. (Chief Investigator (CI)), Ramialison, M. (Chief Investigator (CI)), Martino, M. (Chief Investigator (CI)), Lieschke, G. (Chief Investigator (CI)), Nillegoda, N. (Chief Investigator (CI)) & Anko, M.-L. (Chief Investigator (CI))
1/01/21 → 31/12/21
Project: Research
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Tapping the power of pluripotency: The role of HMGA1 protein in stem cell renewal and cell fate transitions.
Anko, M.-L. (Primary Chief Investigator (PCI)), Kaslin, J. (Chief Investigator (CI)), Davidovich, C. (Chief Investigator (CI)) & Ramialison, M. (Chief Investigator (CI))
1/01/18 → 31/12/20
Project: Research
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Epigenomics and transcriptomics profiles of developing zebrafish heart cells
Chahal, G., Eichenlaub, M. P., Tondl, M., Pawlak, M., Mohenska, M., Grimm, L., Bottrell, L., Drvodelic, M., Alaei, S., Hallab, J., Waylen, L. N., Polo, J. M., Blanpain, C., Palpant, N., Rossello, F. J., Änkö, M. L., Currie, P. D., Hogan, B. M., Winata, C. & Salimova, E. & 2 others, , 7 Oct 2025, In: Scientific Data. 12, 1, 10 p., 1620.Research output: Contribution to journal › Article › Research › peer-review
Open Access1 Link opens in a new tab Citation (Scopus) -
High ploidy large cytoplasmic megakaryocytes are hematopoietic stem cells regulators and essential for platelet production
Heazlewood, S. Y., Ahmad, T., Cao, B., Cao, H., Domingues, M., Sun, X., Heazlewood, C. K., Li, S., Williams, B., Fulton, M., White, J. F., Nebl, T., Nefzger, C. M., Polo, J. M., Kile, B. T., Kraus, F., Ryan, M. T., Sun, Y. B., Choong, P. F. M. & Ellis, S. L. & 2 others, , Dec 2023, In: Nature Communications. 14, 1, 18 p., 2099.Research output: Contribution to journal › Article › Research › peer-review
Open Access34 Link opens in a new tab Citations (Scopus) -
SRSF3 shapes the structure of miR-17-92 cluster RNA and promotes selective processing of miR-17 and miR-20a
Ratnadiwakara, M., Bahrudeen, M. N. M., Aikio, E., Takabe, P., Engel, R. M., Zahir, Z., Jardé, T., McMurrick, P. J., Abud, H. E. & Änkö, M. L., 5 Jul 2023, In: EMBO Reports. 24, 7, 14 p., e56021.Research output: Contribution to journal › Article › Research › peer-review
Open Access5 Link opens in a new tab Citations (Scopus) -
The RNA-binding protein SRSF3 has an essential role in megakaryocyte maturation and platelet production
Heazlewood, S. Y., Ahmad, T., Mohenska, M., Guo, B. B., Gangatirkar, P., Josefsson, E. C., Ellis, S. L., Ratnadiwakara, M., Cao, H., Cao, B., Heazlewood, C. K., Williams, B., Fulton, M., White, J. F., Ramialison, M., Nilsson, S. K. & Änkö, M. L., 3 Mar 2022, In: Blood. 139, 9, p. 1359-1373 15 p.Research output: Contribution to journal › Article › Research › peer-review
Open Access19 Link opens in a new tab Citations (Scopus) -
An engineered sgsh Mutant Zebrafish recapitulates molecular and behavioural pathobiology of sanfilippo syndrome A/MPS IIIA
Douek, A. M., Khabooshan, M. A., Henry, J., Stamatis, S. A., Kreuder, F., Ramm, G., Änkö, M.-L., Wlodkowic, D. & Kaslin, J., 1 Jun 2021, In: International Journal of Molecular Sciences. 22, 11, 28 p., 5948.Research output: Contribution to journal › Article › Research › peer-review
Open Access12 Link opens in a new tab Citations (Scopus)
Activities
- 1 Editorial responsibility
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Seminars in Cell & Developmental Biology (Journal)
Anko, M.-L. (Editor in chief)
May 2017 → Dec 2017Activity: Publication peer-review and editorial work types › Editorial responsibility