Projects per year
Personal profile
Biography
Associate Professor Miles Sparrow is a gastroenterologist specialising in inflammatory bowel disease (IBD) who is the Director of the IBD Unit at The Alfred Hospital, Melbourne and Adjunct Clinical Associate Professor at Monash University.
His research interests include use and optimisation of immunomodulators, therapeutic drug monitoring, novel E-Health models of care in IBD and clinical trials of novel experimental agents in IBD. He is a member of the Australian-IBD Association, IBD-Melbourne and BRIDGe IBD special interest groups, and is a faculty member of the Cornerstones IBD medical education program.
Research interests
Inflammatory bowel disease clinical trials of experimental new agents
Therapeutic drug monitoring in inflammatory bowel disease of thiopurine immunomodulators and biologic agents
Novel models of care including E-Health in inflammatory bowel disease
Supervision interests
Inflamatory bowel disease clinical research.
Currently qualified to supervise BMedSci medical students and to co-supervise graduate research students. Currently applying for AQF Level 10 qualification to enable primary supervision of gradulat research students.
Clinical activities
Director, Alfred Hospital Inflammatory Bowel Disease Unit and Inflammatory Bowel Disease Clinical Trials program.
Works in private practice at Brighton Gastroenterology Associates.
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
Education/Academic qualification
Medicine, MBBS, University of Melbourne
… → 1995
Research area keywords
- inflammatory bowel disease
Network
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A Phase 2b Randomized, Double-blind, Active and Placebo-controlled, Parallel-group, Multicenter Study to Evaluate the Efficacy and Safety of Induction and Maintenance Combination Therapy with Guselkumab and Golimumab in Participants with Moderately to Severely Active Ulcerative Colitis
Sparrow, M. & McKenzie, J.
20/04/23 → 19/04/25
Project: Research
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A Prospective Randomised Controlled Trial of Adults with Perianal Fistulising Crohn’s Disease and Optimised Therapeutic Infliximab Levels: PROACTIVE Trial
Connor, S., Garden, F., Ding, N., De Cruz, P., Sparrow, M., Liew, D. & D'Souza, B.
1/06/22 → 31/05/25
Project: Research
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A phase 3, multicenter, open-label extension study of oral Ozanimod for moderately to severely active Crohn’s disease.
Sparrow, M. & McKenzie, J.
2/02/22 → 31/12/25
Project: Research
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A phase 3, multicenter, randomized, double-blind, placebo- controlled study of oral ozanimod as maintenance therapy for moderately to severely active Crohn’s disease.
Sparrow, M. & McKenzie, J.
19/01/22 → 31/12/24
Project: Research
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Withdrawal of infliximab or concomitant immunosuppressant therapy in patients with Crohn's disease on combination therapy (SPARE): a multicentre, open-label, randomised controlled trial
Louis, E., Resche-Rigon, M., Laharie, D., Satsangi, J., Ding, N., Siegmund, B., D'Haens, G., Picon, L., Bossuyt, P., Vuitton, L., Irving, P., Viennot, S., Lamb, C. A., Pollok, R., Baert, F., Nachury, M., Fumery, M., Gilletta, C., Almer, S., Ben-Horin, S., & 4 others , Mar 2023, In: The Lancet Gastroenterology & Hepatology. 8, 3, p. 215-227 13 p.Research output: Contribution to journal › Article › Research › peer-review
Open Access6 Citations (Scopus) -
Accuracy of Gastrointestinal Ultrasound and Calprotectin in the Assessment of Inflammation and its Location in Patients with an Ileoanal Pouch
Ardalan, Z. S., Friedman, A. B., Con, D., Chandran, S., Gibson, D., Pham, A., De Cruz, P., Tay, K., Bell, S., Rosella, O., Sparrow, M. P. & Gibson, P. R., Jan 2022, In: Journal of Crohn's and Colitis. 16, 1, p. 79-90 12 p.Research output: Contribution to journal › Article › Research › peer-review
4 Citations (Scopus) -
Acute pouchitis: the condition that time forgot about
Segal, J. P., Kayal, M., Ardalan, Z., Garg, M., Sparrow, M. & Barnes, E., 2022, In: Therapeutic Advances in Gastroenterology. 15, p. 1-3 3 p.Research output: Contribution to journal › Editorial › Other › peer-review
Open Access -
Appropriateness of Medical and Surgical Treatments for Chronic Pouchitis Using RAND/UCLA Appropriateness Methodology
Syal, G., Sparrow, M. P., Velayos, F., Cheifetz, A. S., Devlin, S., Irving, P. M., Kaplan, G. G., Raffals, L. E., Ullman, T., Gecse, K. B., Fleshner, P. R., Lightner, A. L., Siegel, C. A. & Melmed, G. Y., 2022, (Accepted/In press) In: Digestive Diseases and Sciences. 8 p.Research output: Contribution to journal › Article › Research › peer-review
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De-escalation from Dose-Intensified Anti-TNF Therapy Is Successful in the Majority of IBD Patients at 12 Months
Little, R. D., Chu, I. E., Ward, M. G. & Sparrow, M. P., Jan 2022, In: Digestive Diseases and Sciences. 67, 1, p. 259–262 4 p.Research output: Contribution to journal › Article › Research › peer-review
1 Citation (Scopus)