Projects per year
Personal profile
Biography
Associate Professor Michelle Tate is a recognised leader in the fields of viral pathogenesis and immunology. After completing her PhD at the University of Melbourne in 2010, she joined the Centre for Innate Immunity and Infectious Diseases at the Hudson Institute of Medical Research. She now leads the Viral Immunity and Immunopathology research group and serves as Deputy Centre Head.
A/Prof Tate’s research focuses on understanding the molecular mechanisms that drive hyperinflammation and severe disease, particularly in the context of influenza A virus infection. Her work has significantly advanced our understanding of how the host immune response can be therapeutically modulated to reduce the severity of viral disease. Her research has been widely published in leading journals, including PLoS Pathogens, Immunity, eLife, Clinical & Translational Immunology, British Journal of Pharmacology, Journal of Immunology, and Journal of Virology.
In recognition of her contributions, A/Prof Tate has received substantial funding from the NHMRC and MRFF, including both fellowships and grants. She works closely with clinical and commercial partners to translate her discoveries into novel, host-directed therapies for pulmonary diseases, with the goal of developing safer and more effective treatment strategies.
Her achievements have been recognised through numerous national and international awards, including the Australian Institute of Policy and Science (AIPS) Young Tall Poppy Science Award (2018), the Christina Fleischmann Memorial Award from the International Cytokine and Interferon Society (2016), the Victorian Infection and Immunity Network Career Development Award (2016), and a Commendation in the Victorian Premier’s Award for Health & Medical Research (2011).
A/Prof Tate also contributes to the broader scientific community through her roles as an NHMRC peer reviewer, editorial board member for Journal of Virology, Virology Journal, and Pathogens, and active involvement in the Australiasian Virology Society.
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
Education/Academic qualification
Microbiology and Immunology, PhD, University of Melbourne
Award Date: 17 Dec 2010
Research area keywords
- Animal Models
- Virology
- influenza virus
- innate immunity
- inflammation
- Inflammasomes
- Host-Pathogen Interactions
Collaborations and top research areas from the last five years
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Targeting pyroptosis to limit the severity of influenza virus infections
Tate, M. (Primary Chief Investigator (PCI)), Lawlor, K. (Associate Investigator (AI)), Mansell, A. (Associate Investigator (AI)) & Hertzog, P. (Associate Investigator (AI))
1/01/23 → 31/12/26
Project: Research
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Potential of the NLRP3 inflammasome as a biomarker and therapeutic target in silicosis
Tate, M. (Primary Chief Investigator (PCI)) & Mansell, A. (Chief Investigator (CI))
Department of Health, Disability and Ageing (Australia)
1/08/21 → 31/07/24
Project: Research
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Finding the balance – Reducing inflammation during severe influenza infections
Tate, M. (Primary Chief Investigator (PCI)) & Mansell, A. (Chief Investigator (CI))
NHMRC - National Health and Medical Research Council (Australia)
1/01/20 → 31/12/22
Project: Research
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Understanding and modulating hyperinflammation caused by influenza viruses
Tate, M. (Primary Chief Investigator (PCI))
NHMRC - National Health and Medical Research Council (Australia)
1/01/17 → 30/09/21
Project: Research
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The role of the inflammasome in modulating disease during influenza virus infection
Tate, M. (Primary Chief Investigator (PCI))
NHMRC - National Health and Medical Research Council (Australia)
1/01/15 → 31/12/18
Project: Research
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Gasdermin E deficiency limits inflammation and lung damage during influenza virus infection
Rosli, S., Ambrose, R. L., Harpur, C. M., Lam, M., Hodges, C., Barry, K. T., West, A. C., Mansell, A., Lawlor, K. E. & Tate, M. D., 6 Jun 2025, In: Cell Death & Disease. 16, 1, 13 p., 440.Research output: Contribution to journal › Article › Research › peer-review
Open Access1 Citation (Scopus) -
NLRP3 deficiency abrogates silica-induced neutrophil infiltration, pulmonary damage and fibrosis
Lam, M., Barry, K. T., Hodges, C. J., Harpur, C. M., Ong, J. D. H., Rosli, S., West, A. C., Dousha, L., Hertzog, P. J., Mansell, A. & Tate, M. D., 21 Mar 2025, In: Respiratory Research. 26, 1, 17 p., 109.Research output: Contribution to journal › Article › Research › peer-review
Open Access5 Citations (Scopus) -
Twelfth scientific biennial meeting of the Australasian Virology Society: AVS12 2024
Monson, E. A., Loterio, R. K., Roby, J. A., Adhikari, A., Bull, R. A., Carr, J. M., Chatzileontiadou, D. S. M., Cheng, C. X., Coulibaly, F., Davis, S. K., Deerain, J. M., Douglas, M. W., Drummer, H. E., Eyre, N. S., Freppel, W., Gowripalan, A., Grant, E. J., Gras, S., Guthmiller, J. J. & Herrero, L. J. & 19 others, , May 2025, In: Journal of Virology. 99, 5, 14 p., e02255-24.Research output: Contribution to journal › Review Article › Other › peer-review
Open Access -
Harnessing Endogenous Peptide Compounds as Potential Therapeutics for Severe Influenza
West, A. C., Harpur, C. M., Le Page, M. A., Lam, M., Hodges, C., Ely, L. K., Gearing, A. J. & Tate, M. D., 16 Aug 2024, In: The Journal of Infectious Diseases. 230, 2, p. e384-e394 11 p.Research output: Contribution to journal › Article › Research › peer-review
Open Access3 Citations (Scopus) -
Interferon epsilon is produced in the testis and protects the male reproductive tract against virus infection, inflammation and damage
Wijayarathna, R., de Geus, E. D., Genovese, R., Gearing, L. J., Wray-McCann, G., Sreenivasan, R., Hasan, H., Fijak, M., Stanton, P., Fietz, D., Pilatz, A., Schuppe, H. C., Tate, M. D., Hertzog, P. J. & Hedger, M. P., 2 Dec 2024, In: PLoS Pathogens. 20, 12, 30 p., e1012702.Research output: Contribution to journal › Article › Research › peer-review
Open Access2 Citations (Scopus)
Prizes
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Chancellor's Prize for Excellence in a PhD Thesis
Tate, M. (Recipient), 2011
Prize: Prize (including medals and awards)
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Christina Fleischmann Memorial Award for Young Women Investigators
Tate, M. (Recipient), 2016
Prize: Prize (including medals and awards)
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Commendation for Premier's Award for Health and Medical Research
Tate, M. (Recipient), 2011
Prize: Prize (including medals and awards)
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Dean's Prize for Excellence in a PhD Thesis
Tate, M. (Recipient), 2011
Prize: Prize (including medals and awards)
Activities
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NHMRC Ideas Grant Peer Review
Tate, M. (Reviewer)
2023Activity: External Academic Engagement › Grant review responsibilities
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Pathogens (Journal)
Tate, M. (Editorial board member)
2020 → …Activity: Publication peer-review and editorial work types › Editorial responsibility
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MRFF Grant Panel
Tate, M. (Reviewer)
2019Activity: External Academic Engagement › Peer review panel or committee
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NHMRC Ideas Grant Panel - Chair
Tate, M. (Chair/ Co-Chair)
2019 → 2020Activity: External Academic Engagement › Peer review panel or committee
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NHMRC Early Career Fellowship - Chair
Tate, M. (Chair/ Co-Chair)
15 Mar 2018 → 31 Aug 2018Activity: External Academic Engagement › Peer review panel or committee
Press/Media
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An early flu season is looming. When's the best time to get vaccinated?
14/04/23
1 Media contribution
Press/Media: Expert Comment
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Pre-clinical study: Novel therapy could provide important flu treatment option
5/04/23
1 item of Media coverage
Press/Media: Research
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New therapy gives important flu treatment option
5/04/23
1 item of Media coverage
Press/Media: Research
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The COVID-flu nexus: how is having COVID around changing our flu season?
27/06/22
1 Media contribution
Press/Media: Expert Comment
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Silicosis research awarded more than $1.6 million – Hudson Institute of Medical Research and Monash University
20/05/21
1 item of Media coverage
Press/Media: Research