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Personal profile

Biography

Dr Michelle Tate is an emerging leader in the fields of viral pathogenesis and immunology. After completing her PhD studies at the University of Melbourne in 2010, Michelle was recruited to the Centre for Innate Immunity and Infectious Diseases within the Hudson Institute of Medical Research under the supervision of Professor Paul Hertzog. Dr Tate is currently a NHMRC Career Development Fellow and head of the Viral Immunity and Immunopathology research group.

Dr Tate’s research interests lie primarily in understanding the molecular mechanisms and pathways involved in the development of hyperinflammation and severe disease, particularly during influenza A virus infection. She has made a number of key contributions to understanding how innate immune defences modulate disease during influenza virus infection, as well as other infectious diseases. Dr Tate’s research has been published in top virology, immunology and multidisciplinary journals such as PLoS PathogensImmunity, eLife, Journal of ImmunologyJournal of Virology and Scientific Reports.

In recognition of her achievements, Dr Tate has been awarded an NHMRC project grant and NHMRC Early Career and Career Development Fellowships. Dr Tate has received numerous national and international awards, including Young Tall Poppy Science Award (2018), the Christina Fleischmann Memorial Award (International Cytokine and Interferon Society 2016), Victorian Infection and Immunity Network Career Development Award (2016) and a Commendation for the Victorian Premier’s Award for Health & Medical Research (2011). In addition, Dr Tate is a member of the Journal of Virology, Virology Journal and Frontiers Viral Immunology editorial boards.

Education/Academic qualification

Microbiology and Immunology, PhD, The University of Melbourne

Research area keywords

  • Animal Models
  • Virology
  • influenza virus
  • innate immunity
  • inflammation
  • Inflammasomes
  • Host-Pathogen Interactions

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Projects 2012 2021

Research Output 2007 2019

ADAM17 selectively activates the IL-6 trans-signaling/ERK MAPK axis in KRAS-addicted lung cancer

Saad, M. I., Alhayyani, S., McLeod, L., Yu, L., Alanazi, M., Deswaerte, V., Tang, K., Jarde, T., Smith, J. A., Prodanovic, Z., Tate, M. D., Balic, J. J., Watkins, D. N., Cain, J. E., Bozinovski, S., Algar, E., Kohmoto, T., Ebi, H., Ferlin, W., Garbers, C. & 4 others, Ruwanpura, S., Sagi, I., Rose-John, S. & Jenkins, B. J., Apr 2019, In : EMBO Molecular Medicine. 11, 4, 19 p., e9976.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
File

Repurposing drugs targeting the P2X7 receptor to limit hyperinflammation and disease during influenza virus infection

Rosli, S., Kirby, F. J., Lawlor, K. E., Rainczuk, K., Drummond, G. R., Mansell, A. & Tate, M. D., Oct 2019, In : British Journal of Pharmacology. 176, 19, p. 3834-3844 11 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
File

RIPLET, and not TRIM25, is required for endogenous RIG-I-dependent antiviral responses

Hayman, T. J., Hsu, A. C., Kolesnik, T. B., Dagley, L. F., Willemsen, J., Tate, M. D., Baker, P. J., Kershaw, N. J., Kedzierski, L., Webb, A. I., Wark, P. A., Kedzierska, K., Masters, S. L., Belz, G. T., Binder, M., Hansbro, P. M., Nicola, N. A. & Nicholson, S. E., Oct 2019, In : Immunology and Cell Biology. 97, 9, p. 840-852 13 p.

Research output: Contribution to journalArticleResearchpeer-review

SIDT1 localizes to endolysosomes and mediates double-stranded RNA transport into the cytoplasm

Nguyen, T. A., Smith, B. R. C., Elgass, K. D., Creed, S. J., Cheung, S., Tate, M. D., Belz, G. T., Wicks, I. P., Masters, S. L. & Pang, K. C., 15 Jun 2019, In : Journal of Immunology. 202, 12, p. 3483-3492 10 p.

Research output: Contribution to journalArticleResearchpeer-review

Tanking influenza a virus in the lung

Rosli, S. & Tate, M. D., 1 Mar 2019, In : American Journal of Respiratory Cell and Molecular Biology. 60, 3, p. 255-256 2 p.

Research output: Contribution to journalEditorialOtherpeer-review

Prizes

Bridging Postdoctoral Fellowship

Michelle Tate (Recipient), 2011

Prize: Competitive Fellowships

Chancellor's Prize for Excellence in a PhD Thesis

Michelle Tate (Recipient), 2011

Prize: Prize (including medals and awards)

Christina Fleischmann Memorial Award for Young Women Investigators

Michelle Tate (Recipient), 2016

Prize: Prize (including medals and awards)

Commendation for Premier's Award for Health and Medical Research

Michelle Tate (Recipient), 2011

Prize: Prize (including medals and awards)

Dean's Prize for Excellence in a PhD Thesis

Michelle Tate (Recipient), 2011

Prize: Prize (including medals and awards)

Activities 2011 2019

  • 4 Peer review panel or committee
  • 3 Editorial responsibility
  • 2 External research organisation, centre or institute

Frontiers in Immunology (Journal)

Michelle Tate (Editorial board member)
2019

Activity: Publication peer-review and editorial work typesEditorial responsibility

NHMRC Ideas Grant Panel - Chair

Michelle Tate (Fellow)
2019 → …

Activity: External Academic EngagementPeer review panel or committee

NHMRC Early Career Fellowship - Panel Chair

Michelle Tate (Fellow)
15 Mar 201831 Aug 2018

Activity: External Academic EngagementPeer review panel or committee

NHMRC Early Career Fellowship - Panel Member

Michelle Tate (Fellow)
1 Mar 201731 Aug 2017

Activity: External Academic EngagementPeer review panel or committee

Journal of Virology (Journal)

Michelle Tate (Editorial board member)
20162021

Activity: Publication peer-review and editorial work typesEditorial responsibility

Press / Media

A second World War drug could help prevent flu deaths

Michelle Tate

15/07/19

1 Media contribution

Press/Media: Article/Feature

Back to the flu-ture

Michelle Tate

11/07/19

1 Media contribution

Press/Media: Article/Feature

Could flu deaths be relegated to history?

Michelle Tate

11/07/19

1 Media contribution

Press/Media: Article/Feature

Flu deaths could be prevented with a drug used during WWII

Michelle Tate

11/07/19

1 Media contribution

Press/Media: Article/Feature