Projects per year
Personal profile
Biography
Associate Professor Michelle Tate is a leader in the fields of viral pathogenesis and immunology. After completing her PhD studies at the University of Melbourne in 2010, Michelle was recruited to the Centre for Innate Immunity and Infectious Diseases within the Hudson Institute of Medical Research. A/Prof Tate currently leads the Viral Immunity and Immunopathology research group and is Deputy Centre Head.
A/Prof Tate’s research interests lie primarily in understanding the molecular mechanisms and pathways involved in the development of hyperinflammation and severe disease, particularly during influenza A virus infection. She has made a number of key contributions to understanding how the host immune system can be therapeutically modulated to limit the development of severe influenza disease. Michelle's research has been published in top virology, immunology, and multidisciplinary journals such as PLoS Pathogens, Immunity, eLife, Clinical & Translational Immunology, British Journal of Pharmacology, Journal of Immunology, and Journal of Virology.
In recognition of her achievements, A/Prof Tate has been awarded significant NHMRC grant funding, including Early Career and Career Development Fellowships. She actively and successfully engages with commercial partners to translate her discoveries, with the vision of developing new safe and effective host-directed treatment strategies for pulmonary diseases.
A/Prof Tate has received numerous national and international awards, including the Australian Institute of Policy and Science (AIPS) Young Tall Poppy Science Award (2018), the Christina Fleischmann Memorial Award (International Cytokine and Interferon Society 2016), Victorian Infection and Immunity Network Career Development Award (2016) and a Commendation for the Victorian Premier’s Award for Health & Medical Research (2011). In addition, A/Prof Tate is a member of the Journal of Virology, Virology Journal, and Pathogens editorial boards.
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
Education/Academic qualification
Microbiology and Immunology, PhD, University of Melbourne
Award Date: 17 Dec 2010
Research area keywords
- Animal Models
- Virology
- influenza virus
- innate immunity
- inflammation
- Inflammasomes
- Host-Pathogen Interactions
Collaborations and top research areas from the last five years
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Targeting pyroptosis to limit the severity of influenza virus infections
Tate, M., Lawlor, K., Mansell, A. & Hertzog, P.
1/01/23 → 31/12/26
Project: Research
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Potential of the NLRP3 inflammasome as a biomarker and therapeutic target in silicosis
Department of Health and Aged Care (Australia)
1/08/21 → 31/07/24
Project: Research
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Toward targeted treatments for silicosis
Barnes, H., Lam, M., Tate, M. D. & Hoy, R., Mar 2024, In: Current Opinion in Pulmonary Medicine. 30, 2, p. 185-194 10 p.Research output: Contribution to journal › Review Article › Research › peer-review
3 Citations (Scopus) -
Aggregated Hendra virus C-protein activates the NLRP3 inflammasome to induce inflammation
Barry, K., Harpur, C., Lam, M., Tate, M. D. & Mansell, A., 10 Nov 2023, In: Journal of Inflammation. 20, 1, 12 p., 38.Research output: Contribution to journal › Article › Research › peer-review
Open Access3 Citations (Scopus) -
A novel dual NLRP1 and NLRP3 inflammasome inhibitor for the treatment of inflammatory diseases
Docherty, C. A. H., Fernando, A. J., Rosli, S., Lam, M., Dolle, R. E., Navia, M. A., Farquhar, R., La France, D., Tate, M. D., Murphy, C. K., Rossi, A. G. & Mansell, A., 22 Jun 2023, In: Clinical & Translational Immunology. 12, 6, 18 p., e1455.Research output: Contribution to journal › Article › Research › peer-review
Open Access22 Citations (Scopus) -
Constitutive expression and distinct properties of IFN-epsilon protect the female reproductive tract from Zika virus infection
Coldbeck-Shackley, R. C., Romeo, O., Rosli, S., Gearing, L. J., Gould, J. A., Lim, S. S., Van der Hoek, K. H., Eyre, N. S., Shue, B., Robertson, S. A., Best, S. M., Tate, M. D., Hertzog, P. J. & Beard, M. R., 10 Mar 2023, In: PLoS Pathogens. 19, 3, 26 p., e1010843.Research output: Contribution to journal › Article › Research › peer-review
Open Access10 Citations (Scopus) -
Flu on the Brain: Identification of Highly Pathogenic Influenza in the Brains of Wild Carnivores in The Netherlands
Barry, K. T. & Tate, M. D., Sept 2023, In: Pathogens. 12, 9, 2 p., 1111.Research output: Contribution to journal › Editorial › Other › peer-review
Open Access
Prizes
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Chancellor's Prize for Excellence in a PhD Thesis
Tate, Michelle (Recipient), 2011
Prize: Prize (including medals and awards)
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Christina Fleischmann Memorial Award for Young Women Investigators
Tate, Michelle (Recipient), 2016
Prize: Prize (including medals and awards)
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Commendation for Premier's Award for Health and Medical Research
Tate, Michelle (Recipient), 2011
Prize: Prize (including medals and awards)
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Dean's Prize for Excellence in a PhD Thesis
Tate, Michelle (Recipient), 2011
Prize: Prize (including medals and awards)
Activities
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NHMRC Ideas Grant Peer Review
Michelle Tate (Reviewer)
2023Activity: External Academic Engagement › Grant review responsibilities
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Pathogens (Journal)
Michelle Tate (Editorial board member)
2020 → …Activity: Publication peer-review and editorial work types › Editorial responsibility
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NHMRC Ideas Grant Panel - Chair
Michelle Tate (Chair/ Co-Chair)
2019 → 2020Activity: External Academic Engagement › Peer review panel or committee
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MRFF Grant Panel
Michelle Tate (Reviewer)
2019Activity: External Academic Engagement › Peer review panel or committee
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NHMRC Early Career Fellowship - Chair
Michelle Tate (Chair/ Co-Chair)
15 Mar 2018 → 31 Aug 2018Activity: External Academic Engagement › Peer review panel or committee
Press/Media
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An early flu season is looming. When's the best time to get vaccinated?
14/04/23
1 Media contribution
Press/Media: Expert Comment
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New therapy gives important flu treatment option
5/04/23
1 item of Media coverage
Press/Media: Research
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Pre-clinical study: Novel therapy could provide important flu treatment option
5/04/23
1 item of Media coverage
Press/Media: Research
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The COVID-flu nexus: how is having COVID around changing our flu season?
27/06/22
1 Media contribution
Press/Media: Expert Comment
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