Projects per year
Personal profile
Biography
Associate Professor Michelle Tate is an emerging leader in the fields of viral pathogenesis and immunology. After completing her PhD studies at the University of Melbourne in 2010, Michelle was recruited to the Centre for Innate Immunity and Infectious Diseases within the Hudson Institute of Medical Research. A/Prof Tate leads the Viral Immunity and Immunopathology research group and is Deputy Centre Head.
A/Prof Tate’s research interests lie primarily in understanding the molecular mechanisms and pathways involved in the development of hyperinflammation and severe disease, particularly during influenza A virus infection. She has made a number of key contributions to understanding how the host immune system can be therapeutically modulated to limit the development of severe influenza disease. Michelle's research has been published in top virology, immunology and multidisciplinary journals such as PLoS Pathogens, Immunity, eLife, Journal of Immunology, Journal of Virology and Scientific Reports.
In recognition of her achievements, A/Prof Tate has been awarded significant NHMRC grant funding, as well as NHMRC Early Career and Career Development Fellowships. She actively and successfully engages with commercial partners to translate her discoveries, with the vision to develop new safe and effective treatment strategies for pulmonary diseases.
A/Prof Tate has received numerous national and international awards, including AIPS Young Tall Poppy Science Award (2018), the Christina Fleischmann Memorial Award (International Cytokine and Interferon Society 2016), Victorian Infection and Immunity Network Career Development Award (2016) and a Commendation for the Victorian Premier’s Award for Health & Medical Research (2011). In addition, A/Prof Tate is a member of the Journal of Virology, Virology Journal and Pathogens editorial boards.
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
Education/Academic qualification
Microbiology and Immunology, PhD, University of Melbourne
Award Date: 17 Dec 2010
Research area keywords
- Animal Models
- Virology
- influenza virus
- innate immunity
- inflammation
- Inflammasomes
- Host-Pathogen Interactions
Network
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Recognition and interaction of virus by the innate immune system
National Health and Medical Research Council (NHMRC) (Australia)
1/01/12 → 31/12/15
Project: Research
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The role of innate immune responses during influenza-induced asthma exacerbation
1/01/12 → 31/12/12
Project: Research
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Interleukin-1β exacerbates disease and is a potential therapeutic target to reduce pulmonary inflammation during severe influenza A virus infection
Bawazeer, A. O. S., Rosli, S., Harpur, C. M., Docherty, C. A. H., Mansell, A. & Tate, M. D., Aug 2021, In: Immunology and Cell Biology. 99, 7, p. 737-748 12 p.Research output: Contribution to journal › Article › Research › peer-review
Open Access3 Citations (Scopus) -
Too young to die? How aging affects cellular innate immune responses to influenza virus and disease severity
Harpur, C. M., Le Page, M. A. & Tate, M. D., 21 Jun 2021, In: Virulence. 12, 1, p. 1629-1646 18 p.Research output: Contribution to journal › Article › Research › peer-review
Open Access -
Animal and translational models of SARS-CoV-2 infection and COVID-19
Johansen, M. D., Irving, A., Montagutelli, X., Tate, M. D., Rudloff, I., Nold, M. F., Hansbro, N. G., Kim, R. Y., Donovan, C., Liu, G., Faiz, A., Short, K. R., Lyons, J. G., McCaughan, G. W., Gorrell, M. D., Cole, A., Moreno, C., Couteur, D., Hesselson, D., Triccas, J. & 9 others, , 13 Nov 2020, In: Mucosal Immunology. 13, 6, p. 877-891 15 p.Research output: Contribution to journal › Review Article › Research › peer-review
88 Citations (Scopus) -
Die Another Way: Interplay between Influenza A Virus, Inflammation and Cell Death
Laghlali, G., Lawlor, K. E. & Tate, M. D., 4 Apr 2020, In: Viruses. 12, 4, 23 p., E401.Research output: Contribution to journal › Review Article › Research › peer-review
Open AccessFile15 Citations (Scopus) -
ADAM17 selectively activates the IL-6 trans-signaling/ERK MAPK axis in KRAS-addicted lung cancer
Saad, M. I., Alhayyani, S., McLeod, L., Yu, L., Alanazi, M., Deswaerte, V., Tang, K., Jarde, T., Smith, J. A., Prodanovic, Z., Tate, M. D., Balic, J. J., Watkins, D. N., Cain, J. E., Bozinovski, S., Algar, E., Kohmoto, T., Ebi, H., Ferlin, W., Garbers, C. & 4 others, , Apr 2019, In: EMBO Molecular Medicine. 11, 4, 19 p., e9976.Research output: Contribution to journal › Article › Research › peer-review
Open AccessFile37 Citations (Scopus)
Prizes
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Chancellor's Prize for Excellence in a PhD Thesis
Tate, Michelle (Recipient), 2011
Prize: Prize (including medals and awards)
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Christina Fleischmann Memorial Award for Young Women Investigators
Tate, Michelle (Recipient), 2016
Prize: Prize (including medals and awards)
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Commendation for Premier's Award for Health and Medical Research
Tate, Michelle (Recipient), 2011
Prize: Prize (including medals and awards)
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Dean's Prize for Excellence in a PhD Thesis
Tate, Michelle (Recipient), 2011
Prize: Prize (including medals and awards)
Activities
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NHMRC Ideas Grant Panel - Chair
Michelle Tate (Fellow)
2019 → …Activity: External Academic Engagement › Peer review panel or committee
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Frontiers in Immunology (Journal)
Michelle Tate (Editorial board member)
2019Activity: Publication peer-review and editorial work types › Editorial responsibility
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NHMRC Early Career Fellowship - Panel Chair
Michelle Tate (Fellow)
15 Mar 2018 → 31 Aug 2018Activity: External Academic Engagement › Peer review panel or committee
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NHMRC Early Career Fellowship - Panel Member
Michelle Tate (Fellow)
1 Mar 2017 → 31 Aug 2017Activity: External Academic Engagement › Peer review panel or committee
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Journal of Virology (Journal)
Michelle Tate (Editorial board member)
2016 → 2021Activity: Publication peer-review and editorial work types › Editorial responsibility
Press / Media
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A second World War drug could help prevent flu deaths
15/07/19
1 Media contribution
Press/Media: Article/Feature
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Flu deaths could be prevented with a drug used during WWII
11/07/19
1 Media contribution
Press/Media: Article/Feature
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