Projects per year
Personal profile
Biography
Michael Chopin is leading an innovative research program that investigates the transcriptional programming of the sentinels of the immune system: the Dendritic Cells (DCs). He graduated from Max Planck Institute for Molecular biology and Bioengineering (Dresden-Germany), and then joined the laboratory of Prof. Stephen Nutt at the Walter and Eliza Hall Institute as a post-doctoral fellow.
Using state-of-the-arts genomics technologies, his postdoctoral studies have been essential to make new, impactful discoveries about cell fate decisions. These approaches include the generation of new conditional mouse mutagenesis models, genomic techniques, and novel cellular differentiation models for DCs; key innovations in the study of this fragile cell type.
In 2022, he established an independent research group at Monash University that is focusing on the molecular mechanisms underpinning DC differentiation and function.
Education/Academic qualification
Immunology, PhD
Award Date: 20 Nov 2011
External positions
Senior Postdoctoral Fellow (B), Walter and Eliza Hall Institute of Medical Research (WEHI)
2013 → 2022
Postdoctoral Fellow (A), Walter and Eliza Hall Institute of Medical Research (WEHI)
2011 → 2013
PhD Candidate, Max Planck Institut fur molekulare Zellbiologie und Genetik (Max Planck Institute of Molecular Cell Biology and Genetics)
2006 → 2010
Research Associate, Mount Sinai Health System
2004 → 2006
Research Associate, Medical College of Georgia
2003 → 2004
Research Associate, Pontificia Universidad Catolica del Ecuador (Pontifical Catholic University of Ecuador)
2001 → 2002
Research area keywords
- transcription factors
- Dendritic Cell
- Dendritic Cell Function
- cancer
- Immunity
- Cytokine
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
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SDG 3 Good Health and Well-being -
SDG 4 Quality Education
Collaborations and top research areas from the last five years
Recent external collaboration on country/territory level. Dive into details by clicking on the dots or
Projects
- 1 Finished
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Tailoring dendritic cell diversity to advance effective immunotherapies
Chopin, M. (Primary Chief Investigator (PCI)) & Dadley-Moore, D. (Sponsor)
3/07/22 → 31/12/25
Project: Research
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Adjusting the scope of natural killer cells in cancer therapy
Shen, Z., Meng, X., Rautela, J., Chopin, M. & Huntington, N. D., Jul 2025, In: Cellular & Molecular Immunology. 22, 7, p. 699-711 13 p.Research output: Contribution to journal › Review Article › Research › peer-review
Open Access24 Link opens in a new tab Citations (Scopus) -
IKAROS and AIOLOS directly regulate AP-1 transcriptional complexes and are essential for NK cell development
Goh, W., Sudholz, H., Foroutan, M., Scheer, S., Pfefferle, A., Delconte, R. B., Meng, X., Shen, Z., Hennessey, R., Kong, I. Y., Schuster, I. S., Andoniou, C. E., Davis, M. J., Hediyeh-Zadeh, S., Souza-Fonseca-Guimaraes, F., Parish, I. A., Beavis, P., Thiele, D., Chopin, M. & Degli-Esposti, M. A. & 5 others, , 2024, In: Nature Immunology. 25, 25 p.Research output: Contribution to journal › Article › Research › peer-review
24 Link opens in a new tab Citations (Scopus) -
Mis-expression of GATA6 re-programs cell fate during early hematopoiesis
Audiger, C., Laâbi, Y., Nie, J., Gibson, L., Wilson-Annan, J., Brook-Carter, P., Kueh, A., Harris, A. W., Naik, S., Nutt, S. L., Strasser, A., Adams, J. M., Bouillet, P. & Chopin, M., 28 May 2024, In: Cell Reports. 43, 5, 13 p., 114159.Research output: Contribution to journal › Article › Research › peer-review
Open Access2 Link opens in a new tab Citations (Scopus) -
CD4+ T cell calibration of antigen-presenting cells optimizes antiviral CD8+ T cell immunity
Gressier, E., Schulte-Schrepping, J., Petrov, L., Brumhard, S., Stubbemann, P., Hiller, A., Obermayer, B., Spitzer, J., Kostevc, T., Whitney, P. G., Bachem, A., Odainic, A., van de Sandt, C., Nguyen, T. H. O., Ashhurst, T., Wilson, K., Oates, C. V. L., Gearing, L. J., Meischel, T. & Hochheiser, K. & 22 others, , Jun 2023, In: Nature Immunology. 24, 6, p. 979-990 12 p.Research output: Contribution to journal › Article › Research › peer-review
34 Link opens in a new tab Citations (Scopus) -
CIS controls the functional polarization of GM-CSF-derived macrophages
Zhang, S., Rautela, J., Bediaga, N. G., Kolesnik, T. B., You, Y., Nie, J., Dagley, L. F., Bedo, J., Wang, H., Sun, L., Sutherland, R., Surgenor, E., Iannarella, N., Allan, R., Souza-Fonseca-Guimaraes, F., Xie, Y., Wang, Q., Zhang, Y., Xu, Y. & Nutt, S. L. & 5 others, , Jan 2023, In: Cellular & Molecular Immunology. 20, 1, p. 65–79 15 p.Research output: Contribution to journal › Article › Research › peer-review
15 Link opens in a new tab Citations (Scopus)
Prizes
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DC 2016-Chinese Society of Immunology Award
Chopin, M. (Recipient), 2016
Prize: Prize (including medals and awards)
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Jenny Thatchell/Pauline Speedy Innovation Award
Chopin, M. (Recipient), 2020
Prize: Prize (including medals and awards)
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The Barbara McDonald Innovation Award
Chopin, M. (Recipient), 2019
Prize: Prize (including medals and awards)
Press/Media
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Study Reveals Two Types Of Langerhans Cells
21/11/13 → 2/04/22
10 items of Media coverage, 1 Media contribution
Press/Media: Blogs, Podcasts and Social Media › Blogs
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Flipping the Script
16/05/21
1 Media contribution
Press/Media: Blogs, Podcasts and Social Media › Blogs