1987 …2021

Research output per year

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Personal profile

Biography

Our group focuses on peptide-based drug design, membrane biology and biomaterials. We are developing novel compounds that allow us to exploit the potential of peptides as drugs and are currently applying our technology to new compounds for treatments of cardiovascular disease. Our membrane biology projects involve the development of new methods for membrane protein analysis with application to apoptosis, G protein-coupled receptor function and antimicrobial peptide function. We are also applying our recently developed peptide-based materials to the development of new scaffolds for stem cell growth and tissue regeneration.

The long-term aim of these studies is to increase our understanding of the molecular basis of peptide and protein function and allow the rational design of peptide and protein based therapeutics.

Research area keywords

  • Peptides
  • Biomembranes
  • Peptide Drugs
  • Bionanotechnology

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Projects

Research Output

Peptidomimetic Modulators of BACE1

Juliano, J. P., Small, D. H. & Aguilar, M. I., 2 Mar 2020, (Accepted/In press) In : Australian Journal of Chemistry. 11 p.

Research output: Contribution to journalArticleResearchpeer-review

The Effect of Charge on Melittin-Induced Changes in Membrane Structure and Morphology

Lee, T-H., Hall, K. & Aguilar, M-I., 2020, In : Australian Journal of Chemistry. 73, 3, p. 195-201 7 p.

Research output: Contribution to journalArticleResearchpeer-review

The use of bioactive matrices in regenerative therapies for traumatic brain injury

Tan, H. X., Del Borgo, M. P., Aguilar, M-I., Forsythe, J. S., Taylor, J. M. & Crack, P. J., 15 Jan 2020, In : Acta Biomaterialia. 102, p. 1-12 12 p.

Research output: Contribution to journalReview ArticleOtherpeer-review

A comment by Prof. Mibel Aguilar—2018 recipient of the Australian Society for Biophysics’ McAulay-Hope Prize for Original Biophysics

Aguilar, M-I., 1 Jun 2019, In : Biophysical Reviews. 11, 3, p. 271-272 2 p.

Research output: Contribution to journalLetterOtherpeer-review

1 Citation (Scopus)

Migration and Differentiation of Neural Stem Cells Diverted From the Subventricular Zone by an Injectable Self-Assembling β-Peptide Hydrogel

Motamed, S., Del Borgo, M. P., Zhou, K., Kulkarni, K., Crack, P. J., Merson, T. D., Aguilar, M-I., Finkelstein, D. I. & Forsythe, J. S., 8 Nov 2019, In : Frontiers in Bioengineering and Biotechnology. 7, 12 p., 315.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
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2 Citations (Scopus)

Activities

  • 1 Membership of industry collaboration/ network

Monash Antimicrobial Resistance Group (Event)

Trevor Lithgow (Chair/Co-Chair), , Max Cryle (Member), , Kellie Tuck (Member), , Ana Traven (Member), , Thomas Naderer (Member), , Julian Rood (Member), , Dena Lyras (Member), , Anton Peleg (Member), , Mibel Aguilar (Member), , Fasseli Coulibaly (Member), , Sheena McGowan (Member), , Meredith Anne Okeeffe (Member), , Matthew Belousoff (Member), & Philip Heraud (Member)

1 Mar 20171 Jan 2019

Activity: Industry, Government and Philanthropy Engagement and PartnershipsMembership of industry collaboration/ network