Projects per year
Personal profile
Biography
Our group focuses on peptide-based drug design, membrane biology and biomaterials. We are developing novel compounds that allow us to exploit the potential of peptides as drugs and are currently applying our technology to new compounds for treatments of cardiovascular disease. Our membrane biology projects involve the development of new methods for membrane protein analysis with application to apoptosis, G protein-coupled receptor function and antimicrobial peptide function. We are also applying our recently developed peptide-based materials to the development of new scaffolds for stem cell growth and tissue regeneration.
The long-term aim of these studies is to increase our understanding of the molecular basis of peptide and protein function and allow the rational design of peptide and protein based therapeutics.
Research area keywords
- Peptides
- Biomembranes
- Peptide Drugs
- Bionanotechnology
Network
Recent external collaboration on country level. Dive into details by clicking on the dots.
Projects
Atomic Scale Precision Engineering of Cell-Material Interfaces
Aguilar, M., Yarovsky, I. & Serpell, L. C.
1/01/19 → 31/12/21
Project: Research
From a Venom to a Potential Treatment for Alzheimer's Disease
Kuruppu, S., Rajapakse, N., Parkington, H., Smith, I., Aguilar, M. & Martins, R. N.
30/09/18 → 31/05/21
Project: Research
Mechanism of Bacterial Membrane Resistance to Antimicrobial Peptides
Aguilar, M., Reid, G. & Separovic, F.
1/01/18 → 31/12/20
Project: Research
Research Output
Peptidomimetic Modulators of BACE1
Juliano, J. P., Small, D. H. & Aguilar, M. I., 2 Mar 2020, (Accepted/In press) In : Australian Journal of Chemistry. 11 p.Research output: Contribution to journal › Article › Research › peer-review
The Effect of Charge on Melittin-Induced Changes in Membrane Structure and Morphology
Lee, T-H., Hall, K. & Aguilar, M-I., 2020, In : Australian Journal of Chemistry. 73, 3, p. 195-201 7 p.Research output: Contribution to journal › Article › Research › peer-review
The use of bioactive matrices in regenerative therapies for traumatic brain injury
Tan, H. X., Del Borgo, M. P., Aguilar, M-I., Forsythe, J. S., Taylor, J. M. & Crack, P. J., 15 Jan 2020, In : Acta Biomaterialia. 102, p. 1-12 12 p.Research output: Contribution to journal › Review Article › Other › peer-review
A comment by Prof. Mibel Aguilar—2018 recipient of the Australian Society for Biophysics’ McAulay-Hope Prize for Original Biophysics
Aguilar, M-I., 1 Jun 2019, In : Biophysical Reviews. 11, 3, p. 271-272 2 p.Research output: Contribution to journal › Letter › Other › peer-review
1
Citation
(Scopus)
Migration and Differentiation of Neural Stem Cells Diverted From the Subventricular Zone by an Injectable Self-Assembling β-Peptide Hydrogel
Motamed, S., Del Borgo, M. P., Zhou, K., Kulkarni, K., Crack, P. J., Merson, T. D., Aguilar, M-I., Finkelstein, D. I. & Forsythe, J. S., 8 Nov 2019, In : Frontiers in Bioengineering and Biotechnology. 7, 12 p., 315.Research output: Contribution to journal › Article › Research › peer-review
Open Access
File
2
Citations
(Scopus)
Activities
- 1 Membership of industry collaboration/ network
Monash Antimicrobial Resistance Group (Event)
Trevor Lithgow (Chair/Co-Chair), , Max Cryle (Member), , Kellie Tuck (Member), , Ana Traven (Member), , Thomas Naderer (Member), , Julian Rood (Member), , Dena Lyras (Member), , Anton Peleg (Member), , Mibel Aguilar (Member), , Fasseli Coulibaly (Member), , Sheena McGowan (Member), , Meredith Anne Okeeffe (Member), , Matthew Belousoff (Member), & Philip Heraud (Member)
1 Mar 2017 → 1 Jan 2019
Activity: Industry, Government and Philanthropy Engagement and Partnerships › Membership of industry collaboration/ network