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Research Output 2005 2019

2019

Differences in Systemic IgA Reactivity and Circulating Th Subsets in Healthy Volunteers With Specific Microbiota Enterotypes

Grosserichter-Wagener, C., Radjabzadeh, D., van der Weide, H., Smit, K. N., Kraaij, R., Hays, J. P. & van Zelm, M. C., 1 Jan 2019, In : Frontiers in Immunology. 10, 12 p., 341.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
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Impaired STAT3-Dependent Upregulation of IL2Rα in B Cells of a Patient With a STAT1 Gain-of-Function Mutation

van Zelm, M. C., Bosco, J. J., Aui, P. M., De Jong, S., Hore-Lacy, F., O'Hehir, R. E., Stirling, R. G. & Cameron, P. U., 1 Jan 2019, In : Frontiers in Immunology. 10, 7 p.

Research output: Contribution to journalArticleOtherpeer-review

Open Access

Inferred Allelic Variants of Immunoglobulin Receptor Genes: A System for Their Evaluation, Documentation, and Naming

Ohlin, M., Scheepers, C., Corcoran, M., Lees, W. D., Busse, C. E., Bagnara, D., Thörnqvist, L., Bürckert, J. P., Jackson, K. J. L., Ralph, D., Schramm, C. A., Marthandan, N., Breden, F., Scott, J., Matsen Iv, F. A., Greiff, V., Yaari, G., Kleinstein, S. H., Christley, S., Sherkow, J. S. & 5 othersKossida, S., Lefranc, M. P., van Zelm, M. C., Watson, C. T. & Collins, A. M., 18 Mar 2019, In : Frontiers in Immunology. 10, 13 p., 435.

Research output: Contribution to journalReview ArticleResearchpeer-review

Open Access
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Studying the replication history of human B lymphocytes by real-time quantitative (RQ-)PCR

van Zelm, M. C., 1 Jan 2019, Lymphoma: Methods and Protocols. Küppers, R. (ed.). 2nd ed. New York, NY: Humana Press, p. 127-138 12 p. (Methods in Molecular Biology; vol. 1956).

Research output: Chapter in Book/Report/Conference proceedingChapter (Book)Otherpeer-review

The EuroFlow PID Orientation Tube for Flow Cytometric Diagnostic Screening of Primary Immunodeficiencies of the Lymphoid System

van der Burg, M., Kalina, T., Perez-Andres, M., Vlkova, M., Lopez-Granados, E., Blanco, E., Bonroy, C., Sousa, A. E., Kienzler, A. K., Wentink, M., Mejstríková, E., Šinkorova, V., Stuchly, J., van Zelm, M. C., Orfao, A. & van Dongen, J. J. M., 4 Mar 2019, In : Frontiers in Immunology. 10, 11 p., 246.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
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2018

Absence of surface IgD does not impair naive B cell homeostasis or memory B cell formation in IGHD haploinsufficient humans

Nechvatalova, J., Bartol, S. J. W., Chovancova, Z., Boon, L., Vlkova, M. & Van Zelm, M. C., 1 Oct 2018, In : Journal of Immunology. 201, 7, p. 1928-1935 8 p.

Research output: Contribution to journalArticleResearchpeer-review

Age-associated distribution of normal B-cell and plasma cell subsets in peripheral blood

Blanco, E., Pérez-Andrés, M., Arriba-Méndez, S., Contreras-Sanfeliciano, T., Criado, I., Pelak, O., Serra-Caetano, A., Romero, A., Puig, N., Remesal, A., Torres Canizales, J., López-Granados, E., Kalina, T., Sousa, A. E., van Zelm, M., van der Burg, M., van Dongen, J. J. M., Orfao, A. & on behalf of the EuroFlow PID group, 1 Jun 2018, In : Journal of Allergy and Clinical Immunology. 141, 6, p. 2208-2219.e16 28 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
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Age-dependent pre-vaccination immunity affects the immunogenicity of varicella zoster vaccination in middle-aged adults

van der Heiden, M., de Rond, L. G. H., van Zelm, M. C., Berbers, G. A. M., Boots, A. M. H. & Buisman, A. M., 23 Jan 2018, In : Frontiers in Immunology. 9, JAN, 10 p., 46.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
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An explorative biomarker study for vaccine responsiveness after a primary meningococcal vaccination in middle-aged adults

van der Heiden, M., Berbers, G. A. M., Fuentes, S., van Zelm, M. C., Boots, A. M. H. & Buisman, A. M., 11 Jan 2018, In : Frontiers in Immunology. 8, JAN, 11 p., 1962.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
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Deficiencies in the CD19 complex

Wentink, M. W. J., van Zelm, M. C., van Dongen, J. J. M., Warnatz, K. & van der Burg, M., 1 Oct 2018, In : Clinical Immunology. 195, p. 82-87 6 p.

Research output: Contribution to journalReview ArticleResearchpeer-review

Delayed diagnosis and complications of predominantly antibody deficiencies in a cohort of Australian adults

Slade, C. A., Bosco, J. J., Giang, T. B., Kruse, E., Stirling, R. G., Cameron, P. U., Hore-Lacy, F., Sutherland, M. F., Barnes, S. L., Holdsworth, S., Ojaimi, S., Unglik, G. A., De Luca, J., Patel, M., McComish, J., Spriggs, K., Tran, Y., Auyeung, P., Nicholls, K., O'Hehir, R. E. & 4 othersHodgkin, P. D., Douglass, J. A., Bryant, V. L. & van Zelm, M. C., 14 May 2018, In : Frontiers in Immunology. 9, MAY, 9 p., 694.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
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Dietary Patterns After the Weaning and Lactation Period Are Associated With Celiac Disease Autoimmunity in Children

Barroso, M., Beth, S. A., Voortman, T., Jaddoe, V. W. V., van Zelm, M. C., Moll, H. A. & Kiefte-de Jong, J. C., 1 Jun 2018, In : Gastroenterology. 154, 8, p. 2087-2096.e7 17 p.

Research output: Contribution to journalArticleResearchpeer-review

Epidemic thunderstorm asthma protection with five-grass pollen tablet sublingual immunotherapy: A clinical trial

O'Hehir, R. E., Varese, N. P., Deckert, K., Zubrinich, C. M., Van Zelm, M. C., Rolland, J. M. & Hew, M., 1 Jul 2018, In : American Journal of Respiratory and Critical Care Medicine. 198, 1, p. 126-128 3 p.

Research output: Contribution to journalLetterResearchpeer-review

Expansion of blood IgG4 + B, TH2, and regulatory T cells in patients with IgG4-related disease

Heeringa, J. J., Karim, A. F., van Laar, J. A. M., Verdijk, R. M., Paridaens, D., van Hagen, P. M. & van Zelm, M. C., May 2018, In : Journal of Allergy and Clinical Immunology. 141, 5, p. 1831-1843.e10 23 p.

Research output: Contribution to journalArticleResearchpeer-review

IgE-expressing memory B cells and plasmablasts are increased in blood of children with asthma, food allergy, and atopic dermatitis

Heeringa, J. J., Rijvers, L., Arends, N. J., Driessen, G. J., Pasmans, S. G., van Dongen, J. J. M., de Jongste, J. C. & van Zelm, M. C., 1 Jun 2018, In : Allergy. 73, 6, p. 1331-1336 6 p.

Research output: Contribution to journalArticleResearchpeer-review

In vitro measles virus infection of human lymphocyte subsets demonstrates high susceptibility and permissiveness of both naive and memory B cells

Laksono, B. M., Grosserichter-Wagener, C., de Vries, R. D., Langeveld, S. A. G., Brem, M. D., van Dongen, J. J. M., Katsikis, P. D., Koopmans, M. P. G., van Zelm, M. C. & de Swart, R. L., 1 Apr 2018, In : Journal of Virology. 92, 8, 13 p., e00131-18.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
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Reply

Karim, A. F., Heeringa, J. J., van Laar, J. A. M., Verdijk, R. M., Dik, W. A., Paridaens, A. D., van Hagen, P. M. & van Zelm, M. C., 1 May 2018, In : Journal of Allergy and Clinical Immunology. 141, 5, p. 1958-1960.e4 3 p.

Research output: Contribution to journalLetterOtherpeer-review

Review article: short chain fatty acids as potential therapeutic agents in human gastrointestinal and inflammatory disorders

Gill, P. A., van Zelm, M. C., Muir, J. G. & Gibson, P. R., 1 Jul 2018, In : Alimentary Pharmacology and Therapeutics. 48, 1, p. 15-34 20 p.

Research output: Contribution to journalReview ArticleResearchpeer-review

Open Access
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Studies into the mechanism of measles-associated immune suppression during a measles outbreak in the Netherlands

Laksono, B. M., de Vries, R. D., Verburgh, R. J., Visser, E. G., de Jong, A., Fraaij, P. L. A., Ruijs, W. L. M., Nieuwenhuijse, D. F., van den Ham, H. J., Koopmans, M. P. G., van Zelm, M. C., Osterhaus, A. D. M. E. & de Swart, R. L., 1 Dec 2018, In : Nature Communications. 9, 1, 10 p., 4944.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
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The identification of celiac disease in asymptomatic children: the Generation R Study

Jansen, M. A. E., van Zelm, M., Groeneweg, M., Jaddoe, V. W. V., Dik, W. A., Schreurs, M. W. J., Hooijkaas, H., Moll, H. & Escher, J. C., Mar 2018, In : Journal of Gastroenterology. 53, 3, p. 377-386 10 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
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The Rare Anaphylaxis-Associated FcγRIIa3 Exhibits Distinct Characteristics From the Canonical FcγRIIa1

Anania, J. C., Trist, H., Palmer, C., Tan, P. S., Kouskousis, B., Chenoweth, A., Kent, S., Mackay, G., Hoi, A., Koelmeyer, R., Slade, C. A., Bryant, V. L., Hodgkin, P. D., Aui, P. M., van Zelm, M., Wines, B. D. & Hogarth, P. M., 20 Aug 2018, In : Frontiers in Immunology. 9, 13 p., 1809.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
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Treatment for moderate to severe atopic dermatitis in alpine and moderate maritime climates differentially affects helper T cells and memory B cells in children

Heeringa, J. J., Fieten, K. B., Bruins, F. M., van Hoffen, E., Knol, E. F., Pasmans, S. G. M. A. & van Zelm, M. C., 1 Jun 2018, In : Clinical and Experimental Allergy. 48, 6, p. 679-690 12 p.

Research output: Contribution to journalArticleResearchpeer-review

2017

Abnormalities in CD57+ cytotoxic T cells and Vδ1+ γδT cells in subclinical celiac disease in childhood are affected by cytomegalovirus. The Generation R Study

Jansen, M. A. E., Van Den Heuvel, D., Jaddoe, V. W. V., van Zelm, M. C. & Moll, H. A., Oct 2017, In : Clinical Immunology. 183, p. 233-239 7 p.

Research output: Contribution to journalArticleResearchpeer-review

Chronic signs of memory B cell activation in patients with Behçet's disease are partially restored by anti-tumour necrosis factor treatment

Van Der Houwen, T. B., Van Hagen, P. M., Timmermans, W. M. C., Bartol, S. J. W., Lam, K. H., Kappen, J. H., van Zelm, M. C. & Van Laar, J. A. M., 1 Jan 2017, In : Rheumatology. 56, 1, p. 134-144 11 p.

Research output: Contribution to journalArticleResearchpeer-review

Differentiation stage of myeloma plasma cells: Biological and clinical significance

GEM (Grupo Español de MM)/PETHEMA (Programa para el Estudio de la Terapéutica en Hemopatías Malignas) cooperative study groups, 2017, In : Leukemia. 31, p. 382-392 11 p.

Research output: Contribution to journalArticleResearchpeer-review

Effects of nongenetic factors on immune cell dynamics in early childhood: The Generation R Study

van den Heuvel, D., Jansen, M. A. E., Nasserinejad, K., Dik, W. A., van Lochem, E. G., Bakker-Jonges, L. E., Bouallouch-Charif, H., Jaddoe, V. W. V., Hooijkaas, H., van Dongen, J. J. M., Moll, H. A. & van Zelm, M. C., Jun 2017, In : Journal of Allergy and Clinical Immunology. 139, 6, p. 1923–1934.e17 29 p.

Research output: Contribution to journalArticleResearchpeer-review

Ethnic differences in coeliac disease autoimmunity in childhood: The Generation R Study

Jansen, M. A. E., Beth, S. A., van den Heuvel, D., Kiefte-de Jong, J. C., Raat, H., Jaddoe, V. W. V., van Zelm, M. C. & Moll, H. A., Jun 2017, In : Archives of Disease in Childhood. 102, 6, p. 529-534 6 p.

Research output: Contribution to journalArticleResearchpeer-review

Human IgG2- and IgG4-expressing memory B cells display enhanced molecular and phenotypic signs of maturity and accumulate with age

De Jong, B. G., Ijspeert, H., Marques, L., Van Der Burg, M., Van Dongen, J. J. M., Loos, B. G. & Van Zelm, M. C., 1 Oct 2017, In : Immunology and Cell Biology. 95, 9, p. 744-752 9 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
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Human Secretory IgM Emerges from Plasma Cells Clonally Related to Gut Memory B Cells and Targets Highly Diverse Commensals

Magri, G., Comerma, L., Pybus, M., Sintes, J., Lligé, D., Segura-Garzón, D., Bascones, S., Yeste, A., Grasset, E. K., Gutzeit, C., Uzzan, M., Ramanujam, M., van Zelm, M. C., Albero-González, R., Vazquez, I., Iglesias, M., Serrano, S., Márquez, L., Mercade, E., Mehandru, S. & 1 othersCerutti, A., 18 Jul 2017, In : Immunity. 47, 1, p. 118-134 17 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
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No interactive effects of sex and persistent cytomegalovirus on immune phenotypes in young children: The generation R study

Jansen, M. A. E., Van Den Heuvel, D., Jaddoe, V. W. V., Moll, H. A. & Van Zelm, M. C., 15 Mar 2017, In : Journal of Infectious Diseases. 215, 6, p. 883-888 6 p.

Research output: Contribution to journalArticleResearchpeer-review

T and B cell markers in dried blood spots of neonates with congenital cytomegalovirus infection: B cell numbers at birth are associated with long-term outcomes

Rovito, R., Korndewal, M. J., Van Zelm, M. C., Ziagkos, D., Wessels, E., Van Der Burg, M., Kroes, A. C. M., Langerak, A. W. & Vossen, A. C. T. M., 1 Jan 2017, In : Journal of Immunology. 198, 1, p. 102-109 8 p.

Research output: Contribution to journalArticleResearchpeer-review

The role of vitamin D on circulating memory T cells in children: The Generation R study

Looman, K. I. M., Jansen, M. A. E., Voortman, T., van den Heuvel, D., Jaddoe, V. W. V., Franco, O. H., van Zelm, M. C. & Moll, H. A., 1 Sep 2017, In : Pediatric Allergy and Immunology. 28, 6, p. 579-587 9 p.

Research output: Contribution to journalArticleResearchpeer-review

Transient reduction in IgA+ and IgG+ memory B cell numbers in young EBV-seropositive children: The generation R study

van den Heuvel, D., Jansen, M. A. E., Bell, A. I., Rickinson, A. B., Jaddoe, V. W. V., van Dongen, J. J. M., Moll, H. A. & van Zelm, M. C., 1 Apr 2017, In : Journal of leukocyte biology. 101, 4, p. 949-956 8 p.

Research output: Contribution to journalArticleResearchpeer-review

2016

B-cell dysregulation in Crohn's disease is partially restored with infliximab therapy

Timmermans, W. M. C., van Laar, J. A. M., van der Houwen, T. B., Kamphuis, L. S. J., Bartol, S. J. W., Lam, K. H., Ouwendijk, R. J., Sparrow, M. P., Gibson, P. R., van Hagen, P. M. & van Zelm, M. C., 1 Jul 2016, In : PLoS ONE. 11, 7, 15 p., e0160103.

Research output: Contribution to journalArticleResearchpeer-review

Open Access

Cell type specific DNA methylation in cord blood: A 450K-reference data set and cell count-based validation of estimated cell type composition

Gervin, K., Page, C. M., Aass, H. C. D., Jansen, M. A., Fjeldstad, H. E., Andreassen, B. K., Duijts, L., van Meurs, J. B., van Zelm, M. C., Jaddoe, V. W., Nordeng, H., Knudsen, G. P., Magnus, P., Nystad, W., Staff, A. C., Felix, J. F. & Lyle, R., 1 Sep 2016, In : Epigenetics. 11, 9, p. 690-698 9 p.

Research output: Contribution to journalArticleResearchpeer-review

Cytomegalovirus- and epstein-barr virus-induced T-cell expansions in young children do not impair naive T-cell populations or vaccination responses: The Generation R study

Van Den Heuvel, D., Jansen, M. A. E., Dik, W. A., Bouallouch-Charif, H., Zhao, D., Van Kester, K. A. M., Smits-Te Nijenhuis, M. A. W., Kolijn-Couwenberg, M. J., Jaddoe, V. W. V., Arens, R., Van Dongen, J. J. M., Moll, H. A. & Van Zelm, M. C., 15 Jan 2016, In : Journal of Infectious Diseases. 213, 2, p. 233-242 10 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
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Decreased IL7Rα and TdT expression underlie the skewed immunoglobulin repertoire of human B-cell precursors from fetal origin

Rother, M. B., Jensen, K., van der Burg, M., van de Bovenkamp, F. S., Kroek, R., van Ijcken, W. F. J., van der Velden, V. H. J., Cupedo, T., Olstad, O. K., van Dongen, J. J. M. & Van Zelm, M. C., 23 Sep 2016, In : Scientific Reports. 6, 13 p., 33924.

Research output: Contribution to journalArticleResearchpeer-review

Open Access

Determinants of ethnic differences in cytomegalovirus, Epstein-Barr Virus, and herpes simplex virus type 1 Seroprevalence in childhood

Jansen, M. A. E., van den Heuvel, D., Bouthoorn, S. H., Jaddoe, V. W. V., Hooijkaas, H., Raat, H., Fraaij, P. L. A., van Zelm, M. C. & Moll, H. A., 1 Mar 2016, In : Journal of Pediatrics. 170, p. 126-134e6 15 p.

Research output: Contribution to journalArticleResearchpeer-review

Differential effects of cytomegalovirus carriage on the immune phenotype of middle-aged males and females

van der Heiden, M., Van Zelm, M. C., Bartol, S. J. W., de Rond, L. G. H., Berbers, G. A. M., Boots, A. M. H. & Buisman, A. M., 31 May 2016, In : Scientific Reports. 6, p. 1-12 12 p., 26892.

Research output: Contribution to journalArticleResearchpeer-review

Open Access

Generation R birth cohort study shows that specific enamel defects were not associated with elevated serum transglutaminase type 2 antibodies

Beth, S. A., Jansen, M. A. E., Elfrink, M. E. C., Kiefte-de Jong, J. C., Wolvius, E. B., Jaddoe, V. W. V., van Zelm, M. C. & Moll, H. A., 1 Oct 2016, In : Acta Paediatrica. 105, 10, p. e485-e491 7 p.

Research output: Contribution to journalArticleResearchpeer-review

Herpesvirus infections and transglutaminase type 2 antibody positivity in childhood: The Generation R Study

Jansen, M. A. E., van den Heuvel, D., van der Zwet, K. V. M., Jaddoe, V. W. V., Hofman, A., Escher, J. C., Fraaij, P. L. A., Hooijkaas, H., van Zelm, M. C. & Moll, H. A., 2016, In : Journal of Pediatric Gastroenterology and Nutrition. 63, 4, p. 423-430 8 p.

Research output: Contribution to journalArticleResearchpeer-review

Immunopathogenesis of granulomas in chronic autoinflammatory diseases

Timmermans, W. M. C., Van Laar, J. A. M., Van Hagen, P. M. & van Zelm, M. C., 2016, In : Clinical and Translational Immunology. 5, 12 p., e118.

Research output: Contribution to journalReview ArticleResearchpeer-review

Open Access
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Is there a pathogenic role for IgE in psoriasis?

Heeringa, J. J. & van Zelm, M. C., 1 Jul 2016, In : British Journal of Dermatology. 175, 1, p. 16-17 2 p.

Research output: Contribution to journalComment / DebateOtherpeer-review

Nomenclature of CD molecules from the Tenth Human Leucocyte Differentiation Antigen Workshop

Clark, G., Stockinger, H., Balderas, R., van Zelm, M. C., Zola, H., Hart, D. & Engel, P., 1 Jan 2016, In : Clinical and Translational Immunology. 5, 1, 3 p., e57.

Research output: Contribution to journalEditorialOtherpeer-review

Open Access
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Nuclear positioning rather than contraction controls ordered rearrangements of immunoglobulin loci

Rother, M. B., Palstra, R. J., Jhunjhunwala, S., van Kester, K. A. M., van IJcken, W. F. J., Hendriks, R. W., van Dongen, J. J. M., Murre, C. & van Zelm, M. C., 8 Jan 2016, In : Nucleic Acids Research. 44, 1, p. 175-186 12 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
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Systemic B-cell abnormalities in patients with atopic dermatitis?

Heeringa, J. J., Hajdarbegovic, E., Thio, H. B. & van Zelm, M. C., 2016, In : Journal of Allergy and Clinical Immunology. 138, 1, p. 317-318 2 p.

Research output: Contribution to journalArticleOtherpeer-review

The human thymus is enriched for autoreactive B cells

Rother, M. B., Schreurs, M. W. J., Kroek, R., Bartol, S. J. W., Van Dongen, J. J. M. & Van Zelm, M. C., 15 Jul 2016, In : Journal of Immunology. 197, 2, p. 441-448 8 p.

Research output: Contribution to journalArticleResearchpeer-review

2015

A mutation in the human tetraspanin CD81 gene is expressed as a truncated protein but does not enable CD19 maturation and cell surface expression

Vences-Catalán, F., Kuo, C. C., Sagi, Y., Chen, H., Kela-Madar, N., van Zelm, M. C., van Dongen, J. J. M. & Levy, S., 2015, In : Journal of Clinical Immunology. 35, 3, p. 254-263 10 p.

Research output: Contribution to journalArticleResearchpeer-review

Basal Ca2+ signaling is particularly increased in mutated chronic lymphocytic leukemia

Muggen, A. F., Pillai, S. Y., Kil, L. P., Van Zelm, M. C., Van Dongen, J. J. M., Hendriks, R. W. & Langerak, A. W., 7 Feb 2015, In : Leukemia. 29, 2, p. 321-328 8 p.

Research output: Contribution to journalArticleResearchpeer-review

CD21 and CD19 deficiency: Two defects in the same complex leading to different disease modalities

Wentink, M. W. J., Lambeck, A. J. A., van Zelm, M. C., Simons, E., van Dongen, J. J. M., Ijspeert, H., Schölvinck, E. H. & van der Burg, M., 1 Dec 2015, In : Clinical Immunology. 161, 2, p. 120-127 8 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
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