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Personal profile

Biography

The aim of our research is to determine imaging, genomic, other biomarkers in the early diagnosis of neurogenerative diseases (e.g. Alzheimers Disease), apply artificial intelligence for diagnoses and test new therapeutic agents in clinical trials.

Our research centres on pre-clinical and translational clinical imaging in neurological disease but also some non-neurological diseases. We utilize state of the art and ultra-high field MRI, PET, CT, magnetic particle imaging, photon microscopy approaches towards imaging pathology. We also house a data warehouse and repository for imaging, genomics, biomarker, pathology and other data to be used for machine learning, deep learning, artificial intelligence applications in diagnostics and therapeutics. We also perform pre-clinical and clinical trials on novel therapeutics in neurodegenerative diseases and non-neurological diseases.

External positions

Head of Diagnostic and Interventional Radiology research, Alfred Health

Research area keywords

  • Neuroscience
  • Alzheimer's Disease
  • Artificial intelligence
  • Imaging
  • Radiology, Radiography, Ultrasound, Imaging, Evidence Based Practice
  • Traumatic brain injury
  • MRI
  • Neuroimaging
  • Informatics
  • Bioinformatics

Network Recent external collaboration on country level. Dive into details by clicking on the dots.

Projects 2018 2021

Research Output 1997 2019

1 Citation (Scopus)

7-Tesla MRI of the brain in a research subject with bilateral, total knee replacement implants: Case report and proposed safety guidelines

Barisano, G., Culo, B., Shellock, F. G., Sepehrband, F., Martin, K., Stevens, M., Wang, D. J., Toga, A. W. & Law, M., 1 Apr 2019, In : Magnetic Resonance Imaging. 57, p. 313-316 4 p.

Research output: Contribution to journalArticleOtherpeer-review

1 Citation (Scopus)

Assessment of metallic patient support devices and other items at 7-Tesla: Findings applied to 46 additional devices

Culo, B., Valencerina, S., Law, M. & Shellock, F. G., 1 Apr 2019, In : Magnetic Resonance Imaging. 57, p. 250-253 4 p.

Research output: Contribution to journalArticleResearchpeer-review

Blood-based inflammatory biomarkers for predicting therapeutic response in regional brain volume changes in patients with alzheimer’s disease

Mishra, A., Hernandez, G. D., Lopez, C., Aydogan, D., Shi, Y., Law, M., Schneider, L. S. & Brinton, R. D., Jul 2019, In : Alzheimer's and Dementia. 15, 7 Supp, 1 p.

Research output: Contribution to journalMeeting AbstractOtherpeer-review

55 Citations (Scopus)

Blood–brain barrier breakdown is an early biomarker of human cognitive dysfunction

Nation, D. A., Sweeney, M. D., Montagne, A., Sagare, A. P., D’Orazio, L. M., Pachicano, M., Sepehrband, F., Nelson, A. R., Buennagel, D. P., Harrington, M. G., Benzinger, T. L. S., Fagan, A. M., Ringman, J. M., Schneider, L. S., Morris, J. C., Chui, H. C., Law, M., Toga, A. W. & Zlokovic, B. V., 1 Feb 2019, In : Nature Medicine. 25, 2, p. 270-276-+ 20 p.

Research output: Contribution to journalArticleResearchpeer-review

Brain imaging of vascular dysfunction as an early biomarker of cognitive decline

Montagne, A., Sweeney, M. D., Sagare, A. P., Nation, D. A., Harrington, M. G., Chui, H. C., Law, M., Toga, A. W. & Zlokovic, B. V., Jul 2019, In : Alzheimer's and Dementia. 15, 7 Supp, 1 p.

Research output: Contribution to journalMeeting AbstractOtherpeer-review