Melissa Southey

Professor

Accepting PhD Students

1990 …2024
If you made any changes in Pure these will be visible here soon.

Research Output 1990 2019

Filter
Article
2013

Functional variants at the 11q13 risk locus for breast cancer regulate cyclin D1 expression through long-range enhancers

French, J. D., Ghoussaini, M., Edwards, S. L., Meyer, K. B., Michailidou, K., Ahmed, S., Khan, S., Maranian, M. J., O'Reilly, M., Hillman, K. M., Betts, J. A., Carroll, T., Bailey, P. J., Dicks, E., Beesley, J., Tyrer, J., Maia, A-T., Beck, A. H., Knoblauch, N. W., Chen, C. & 191 othersKraft, P., Barnes, D., González-Neira, A., Alonso, M. R., Herrero, D., Tessier, D. C., Vincent, D., Bacot, F., Luccarini, C., Baynes, C., Conroy, D. M., Dennis, J., Bolla, M. K., Wang, Q., Hopper, J. L., Southey, M. C., Schmidt, M. K., Broeks, A., Verhoef, S., Cornelissen, S., Muir, K., Lophatananon, A., Stewart-Brown, S., Siriwanarangsan, P., Fasching, P. A., Loehberg, C. R., Ekici, A. B., Beckmann, M. W., Peto, J., Dos Santos Silva, I., Johnson, N., Aitken, Z., Sawyer, E. J., Tomlinson, I. P., Kerin, M. J., Miller, N., Marme, F., Schneeweiss, A., Sohn, C., Burwinkel, B., Guénel, P., Truong, T., Laurent-Puig, P., Menegaux, F., Bojesen, S. E., Nordestgaard, B. G., Nielsen, S. F., Flyger, H., Milne, R. L., Zamora, P. M., Arias Perez, J. I., Benitez, J., Anton-Culver, H., Brenner, H., Müller, H., Arndt, V., Stegmaier, C., Meindl, A., Lichtner, P., Schmutzler, R. K., Engel, C., Brauch, H., Hamann, U., Justenhoven, C., Aaltonen, K., Heikkilä, P., Aittomäki, K., Blomqvist, C., Matsuo, K., Ito, H., Iwata, H., Sueta, A., Bogdanova, N. V., Antonenkova, N., Dörk, T., Lindblom, A., Margolin, S., Mannermaa, A., Kataja, V., Kosma, V-M., Hartikainen, J. M., Wu, A. H., Tseng, C-C., Berg, D., Stram, D. O., Lambrechts, D., Peeters, S., Smeets, A., Floris, G., Chang-Claude, J., Rudolph, A., Nickels, S., Flesch-Janys, D., Radice, P., Peterlongo, P., Bonanni, B., Sardella, D., Couch, F. J., Wang, X., Pankratz, V. S., Lee, A. F., Giles, G. G., Severi, G., Baglietto, L., Haiman, C. A., Henderson, B. E., Schumacher, F., Le Marchand, L., Simard, J., Goldberg, M. S., Labrèche, F., Dumont, M., Teo, S-H., Yip, C. H., Ng, C. H., Vithana, E. N., Kristensen, V., Zheng, W., Deming-Halverson, S., Shrubsole, M., Long, J., Winqvist, R., Pylkäs, K., Jukkola-Vuorinen, A., Grip, M., Andrulis, I. L., Knight, J. A., Glendon, G., Mulligan, A. M., Devilee, P., Seynaeve, C., García-Closas, M., Figueroa, J. D., Chanock, S. J., Lissowska, J., Czene, K., Klevebring, D., Schoof, N., Hooning, M. J., Martens, J. W. M., Collée, J. M., Tilanus-Linthorst, M. M. A., Hall, P., Li, J., Liu, J., Humphreys, K., Shu, X-O., Lu, W., Gao, Y-T., Cai, H., Cox, A., Balasubramanian, S. P., Blot, W., Signorello, L. B., Cai, Q., Pharoah, P. D. P., Healey, C. S., Shah, M., Pooley, K. A., Kang, D., Yoo, K-Y., Noh, D-Y., Hartman, M., Miao, H., Sng, J. H., Sim, X., Jakubowska, A., Lubinski, J., Jaworska-Bieniek, K., Durda, K., Sangrajrang, S., Gaborieau, V., McKay, J., Toland, A. E., Ambrosone, C. B., Yannoukakos, D., Godwin, A. K., Shen, C-Y., Hsiung, C-N., Wu, P-E., Chen, S-T., Swerdlow, A. J., Ashworth, A., Orr, N., Schoemaker, M. J., Ponder, B. A. J., Nevanlinna, H., Brown, M. A., Chenevix-Trench, G., Easton, D. F. & Dunning, A. M., 4 Apr 2013, In : American Journal of Human Genetics. 92, 4, p. 489-503 15 p.

Research output: Contribution to journalArticleResearchpeer-review

Genetic modifiers of menopausal hormone replacement therapy and breast cancer risk: A genome-wide interaction study

Rudolph, A., Hein, R., Lindström, S., Beckmann, L., Behrens, S., Liu, J., Aschard, H., Bolla, M. K., Wang, J. S., Truong, T., Cordina-Duverger, E., Menegaux, F., Brüning, T., Harth, V., So, W-Y., Severi, G., Baglietto, L., Southey, M., Chanock, S. J., Lissowska, J. & 35 othersFigueroa, J. D., Eriksson, M., Humpreys, K., Darabi, H., Olson, J. E., Stevens, K. N., Vachon, C. M., Knight, J. A., Glendon, G., Marie Mulligan, A., Ashworth, A., Orr, N., Schoemaker, M., Webb, P. M., Green, A., Parsons, P., Hayward, N., Webb, P. M., Whiteman, D. C., Guenel, P., Brauch, H., Giles, G., Garca-Closas, M., Czene, K., Chenevix-Trench, G., Couch, F. J., Andrulis, I. L., Swerdlow, A. J., Hunter, D. J., Flesch-Janys, D., Easton, D. F., Hall, P., Nevanlinna, H., Kraft, P. & Chang-Claude, J., Dec 2013, In : Endocrine-Related Cancer. 20, 6, p. 875-887 13 p.

Research output: Contribution to journalArticleResearchpeer-review

Genome-wide association studies identify four ER negative-specific breast cancer risk loci

Garcia-Closas, M., Couch, F. J., Lindstrom, S., Michailidou, K., Schmidt, M. K., Brook, M. N., Orr, N., Rhie, S. K., Riboli, E. B., Feigelson, H. S., Le Marchand, L., Buring, J. E., Eccles, D. M., Miron, P., Fasching, P. A., Brauch, H., Chang-Claude, J., Carpenter, J., Godwin, A. K., Nevanlinna, H. & 3 othersGiles, G. G., Southey, M. C. & McLean, C., Apr 2013, In : Nature Genetics. 45, 4, p. 392-398 7 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
File

Genome-Wide Association Study in BRCA1 Mutation Carriers Identifies Novel Loci Associated with Breast and Ovarian Cancer Risk

Couch, F. J., Wang, X., McGuffog, L., Lee, A., Olswold, C., Kuchenbaecker, K. B., Soucy, P., Fredericksen, Z., Barrowdale, D., Dennis, J., Gaudet, M. M., Dicks, E., Kosel, M., Healey, S., Sinilnikova, O. M., Lee, A., Bacot, F., Vincent, D., Hogervorst, F. B. L., Peock, S. & 232 othersStoppa-Lyonnet, D., Jakubowska, A., Radice, P., Schmutzler, R. K., Domchek, S. M., Piedmonte, M., Singer, C. F., Friedman, E., Thomassen, M., Hansen, T. V. O., Neuhausen, S. L., Szabo, C. I., Blanco, I., Greene, M. H., Karlan, B. Y., Garber, J., Phelan, C. M., Weitzel, J. N., Montagna, M., Olah, E., Andrulis, I. L., Godwin, A. K., Yannoukakos, D., Goldgar, D. E., Caldes, T., Nevanlinna, H., Osorio, A., Terry, M. B., Daly, M. B., van Rensburg, E. J., Hamann, U., Ramus, S. J., Ewart Toland, A., Caligo, M. A., Olopade, O. I., Tung, N., Claes, K., Beattie, M. S., Southey, M. C., Imyanitov, E. N., Tischkowitz, M., Janavicius, R., John, E. M., Kwong, A., Diez, O., Balmaña, J., Barkardottir, R. B., Arun, B. K., Rennert, G., Teo, S. H., Ganz, P. A., Campbell, I., van der Hout, A. H., van Deurzen, C. H. M., Seynaeve, C., Gómez Garcia, E. B., van Leeuwen, F. E., Meijers-Heijboer, H. E. J., Gille, J. J. P., Ausems, M. G. E. M., Blok, M. J., Ligtenberg, M. J. L., Rookus, M. A., Devilee, P., Verhoef, S., van Os, T. A. M., Wijnen, J. T., Frost, D., Ellis, S., Fineberg, E., Platte, R., Evans, D. G., Izatt, L., Eeles, R. A., Adlard, J., Eccles, D. M., Cook, J., Brewer, C., Douglas, F., Hodgson, S., Morrison, P. J., Side, L. E., Donaldson, A., Houghton, C., Rogers, M. T., Dorkins, H., Eason, J., Gregory, H., McCann, E., Murray, A., Calender, A., Hardouin, A., Berthet, P., Delnatte, C., Nogues, C., Lasset, C., Houdayer, C., Leroux, D., Rouleau, E., Prieur, F., Damiola, F., Sobol, H., Coupier, I., Venat-Bouvet, L., Castera, L., Gauthier-Villars, M., Léoné, M., Pujol, P., Mazoyer, S., GEMO Study Collaborators, Bignon, Y. J., Złowocka-Perłowska, E., Gronwald, J., Lubinski, J., Durda, K., Jaworska, K., Huzarski, T., Spurdle, A. B., Peissel, B., Bonanni, B., Melloni, G., Ottini, L., Papi, L., Varesco, L., Tibiletti, M. G., Peterlongo, P., Volorio, S., Manoukian, S., Pensotti, V., Arnold, N., Engel, C., Deissler, H., Gadzicki, D., Gehrig, A., Kast, K., Rhiem, K., Meindl, A., Niederacher, D., Ditsch, N., Plendl, H., Preisler-Adams, S., Engert, S., Sutter, C., Varon-Mateeva, R., Wappenschmidt, B., Weber, B. H. F., Arver, B., Stenmark-Askmalm, M., Loman, N., Rosenquist, R., Einbeigi, Z., Nathanson, K. L., Rebbeck, T. R., Blank, S. V., Cohn, D. E., Rodriguez, G. C., Small, L., Friedlander, M., Bae-Jump, V. L., Fink-Retter, A., Rappaport, C., Gschwantler-Kaulich, D., Pfeiler, G., Tea, M. K., Lindor, N. M., Kaufman, B., Shimon Paluch, S., Laitman, Y., Skytte, A. B., Gerdes, A. M., Pedersen, I. S., Moeller, S. T., Kruse, T. A., Jensen, U. B., Vijai, J., Sarrel, K., Robson, M., Kauff, N., Mulligan, A. M., Glendon, G., Ozcelik, H., Ejlertsen, B., Nielsen, F. C., Jønson, L., Andersen, M. K., Ding, Y. C., Steele, L., Foretova, L., Teulé, A., Lazaro, C., Brunet, J., Pujana, M. A., Mai, P. L., Loud, J. T., Walsh, C., Lester, J., Orsulic, S., Narod, S. A., Herzog, J., Sand, S. R., Tognazzo, S., Agata, S., Vaszko, T., Weaver, J., Stavropoulou, A. V., Buys, S. S., Romero, A., de la Hoya, M., Aittomäki, K., Muranen, T. A., Duran, M., Chung, W. K., Lasa, A., Dorfling, C. M., Miron, A., Benitez, J., Senter, L., Huo, D., Chan, S. B., Sokolenko, A. P., Chiquette, J., Tihomirova, L., Friebel, T. M., Agnarsson, B. A., Lu, K. H., Lejbkowicz, F., James, P. A., Hall, P., Dunning, A. M., Tessier, D., Cunningham, J. & on behalf of CIMBA, 1 Jan 2013, In : PLoS Genetics. 9, 3, 21 p., e1003212.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
File

GWAS meta-analysis and replication identifies three new susceptibility loci for ovarian cancer

Pharoah, P. D., Tsai, Y-Y., Ramus, S. J., Phelan, C. M., Goode, E. L., Lawrenson, K., Buckley, M., Fridley, B., Tyrer, J., Shen, H., Weber, R., Karevan, R., Larson, M., Song, H., Tessier, D., Bacot, F., Vincent, D., Cunningham, J., Dennis, J., Dicks, E. & 148 othersAben, K. K., Anton-Culver, H., Antonenkova, N., Armasu, S., Baglietto, L., Bandera, E., Beckmann, M., Birrer, M., Bloom, G., Bogdanova, N., Brenton, J. D., Brinton, L., Brooks-Wilson, A., Brown, R., Butzow, R., Campbell, I. G., Carney, M., Carvalho, R., Chang-Claude, J., Chen, Y. A., Chen, Z., Chow, W-H., Cicek, M. S., Coetzee, G., Cook, L., Cramer, D., Cybulski, C., Dansonka-Mieszkowska, A., Despierre, E., Doherty, J., Dork, T., Du Bois, A., Duerst, M., Eccles, D. M., Edwards, R., Ekici, A. B., Fasching, P., Fenstermacher, D., Flanagan, J., Gao, Y-T., Garcia-Closas, M., Gentry-Maharaj, A., Giles, G., Gjyshi, A., Gore, M., Gronwald, J., Guo, Q., Halle, M., Harter, P., Hein, A., Heitz, F., Hillemanns, P., Hoatlin, M., Hogdall, E., Hogdall, C., Hosono, S., Jakubowska, A., Jensen, A., Kalli, K., Karlan, B., Kelemen, L., Kiemeney, L., Kjaer, S. K., Konecny, G. E., Krakstad, C., Kupryjanczyk, J., Lambrechts, D., Lambrechts, S., Le, N., Lee, N., Lee, J., Leminen, A., Lim, B. K., Lissowska, J., Lubinski, J., Lundvall, L., Lurie, G., Massuger, L. F. A. G., Matsuo, K., McGuire, V., McLaughlin, J. R., Menon, U. N., Modugno, F., Moysich, K. B., Nakanishi, T., Narod, S. A., Ness, R. B., Nevanlinna, H., Nickels, S., Noushmehr, H., Odunsi, K., Olson, S. H., Orlow, I., Paul, J., Pejovic, T., Pelttari, L. M., Permuth-Wey, J., Pike, M. C., Poole, E. M., Qu, X., Risch, H. A., Rodriguez-Rodriguez, L., Rossing, M. A., Rudolph, A., Runnebaum, I. B., Rzepecka, I. K., Salvesen, H. B., Schwaab, I., Severi, G., Shen, H., Shridhar, V., Shu, X-O., Sieh, W., Southey, M. C., Spellman, P., Tajima, K., Teo, S-H., Terry, K. L., Thompson, P. J., Timorek, A., Tworoger, S. S., Van Altena, A. M., Van Den Berg, D., Vergote, I., Vierkant, R. A., Vitonis, A. F., Wang-Gohrke, S., Wentzensen, N., Whittemore, A. S., Wik, E., Winterhoff, B., Woo, Y. L., Wu, A. H., Yang, H. P., Zheng, W., Ziogas, A., Zulkifli, F., Goodman, M. T., Hall, P., Easton, D. F., Pearce, C. L., Berchuck, A., Chenevix-Trench, G., Iversen, E., Monteiro, A., Gayther, S. A., Schildkraut, J. M. & Sellers, T. A., 2013, In : Nature Genetics. 45, 4, p. 362 - 370 9 p.

Research output: Contribution to journalArticleResearchpeer-review

Hi-Plex for high-throughput mutation screening: Application to the breast cancer susceptibility gene PALB2

Nguyen-Dumont, T., Teo, Z. L., Pope, B. J., Hammet, F., Mahmoodi, M., Tsimiklis, H., Sabbaghian, N., Tischkowitz, M., Foulkes, W. D., Giles, G. G., Hopper, J. L., Australian Breast Cancer Family Registry, Southey, M. C. & Park, D. J., 2013, In : BMC Medical Genomics. 6, 1, 5 p., 48.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
File

Identification and molecular characterization of a new ovarian cancer susceptibility locus at 17q21.31

Permuth-Wey, J., Lawrenson, K., Shen, H., Velkova, A., Tyrer, J., Chen, Z., Lin, H-Y. L., Chen, Y. A., Tsai, Y-Y., Qu, X., Ramus, S. J., Karevan, R., Lee, J., Lee, N., Larson, M., Aben, K. K., Anton-Culver, H., Antonenkova, N., Antoniou, A. C., Armasu, S. & 158 othersBacot, F., Baglietto, L., Bandera, E., Barnholtz-Sloan, J. S., Beckmann, M., Birrer, M., Bloom, G., Bogdanova, N., Brinton, L., Brooks-Wilson, A., Brown, R., Butzow, R., Cai, Q., Campbell, I. G., Chang-Claude, J., Chanock, S., Chenevix-Trench, G., Cheng, J. Q., Cicek, M. S., Coetzee, G., Cook, L., Couch, F. J., Cramer, D., Cunningham, J., Dansonka-Mieszkowska, A., Despierre, E., Doherty, J., Dork, T., Du Bois, A., Duerst, M., Easton, D. F., Eccles, D. M., Edwards, R., Ekici, A. B., Fasching, P., Fenstermacher, D., Flanagan, J., Garcia-Closas, M., Gentry-Maharaj, A., Giles, G., Glasspool, R. M., Gonzalez-Bosquet, J., Goodman, M. T., Gore, M., Gorski, B., Gronwald, J., Hall, P., Halle, M., Harter, P., Heitz, F., Hillemanns, P., Hoatlin, M., Hogdall, C., Hogdall, E., Hosono, S., Jakubowska, A., Jensen, A., Jim, H. S., Kalli, K., Karlan, B., Kaye, S. B., Kelemen, L., Kiemeney, L., Kikkawa, F., Konecny, G. E., Krakstad, C., Kjaer, S. K., Kupryjanczyk, J., Lambrechts, D., Lambrechts, S., Lancaster, J. M., Le, N., Leminen, A., Levine, D., Liang, D., Lim, B. K., Lin, J., Lissowska, J., Lu, K., Lubinski, J., Lurie, G., Massuger, L. F. A. G., Matsuo, K., McGuire, V., McLaughlin, J. R., Menon, U. N., Modugno, F., Moysich, K. B., Nakanishi, T., Narod, S. A., Nedergaard, L., Ness, R. B., Nevanlinna, H., Nickels, S., Noushmehr, H., Odunsi, K., Olson, S. H., Orlow, I., Paul, J., Pearce, C. L., Pejovic, T., Pelttari, L. M., Pike, M. C., Poole, E. M., Raska, P., Renner, S. P., Risch, H. A., Rodriguez-Rodriguez, L., Rossing, M. A., Rudolph, A., Runnebaum, I. B., Rzepecka, I. K., Salvesen, H. B., Schwaab, I., Severi, G., Shridhar, V., Shu, X-O., Shvetsov, Y. B., Sieh, W., Song, H., Southey, M. C., Spiewankiewicz, B., Stram, D. O., Sutphen, R., Teo, S-H., Terry, K. L., Tessier, D., Thompson, P. J., Tworoger, S. S., Van Altena, A. M., Vergote, I., Vierkant, R. A., Vincent, D., Vitonis, A. F., Wang-Gohrke, S., Weber, R. P., Wentzensen, N., Whittemore, A. S., Wik, E., Wilkens, L., Winterhoff, B., Woo, Y. L., Wu, A. H., Xiang, Y-B., Yang, H. P., Zheng, W., Ziogas, A., Zulkifli, F., Phelan, C. M., Iversen, E., Schildkraut, J. M., Berchuck, A., Fridley, B., Goode, E. L., Pharoah, P. D., Monteiro, A., Sellers, T. A. & Gayther, S. A., 2013, In : Nature Communications. 4, Art. ID: 1627, p. 1 - 12 12 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access

Identification of 23 new prostate cancer susceptibility loci using the iCOGS custom genotyping array

Eeles, R. A., Al Olama, A. A., Benlloch, S., Saunders, E. J., Leongamornlert, D. A., Tymrakiewicz, M., Ghoussaini, M., Luccarini, C., Dennis, J., Jugurnauth-Little, S., Dadaev, T., Neal, D. E., Hamdy, F. C., Donovan, J. L., Muir, K., Giles, G. G., Severi, G., Wiklund, F., Gronberg, H., Haiman, C. A. & 124 othersSchumacher, F., Henderson, B. E., Le Marchand, L., Lindstrom, S., Kraft, P., Hunter, D. J., Gapstur, S. M., Chanock, S. J., Berndt, S. I., Albanes, D., Andriole, G. L., Schleutker, J., Weischer, M., Canzian, F., Riboli, E. B., Key, T. J., Travis, R. C., Campa, D., Ingles, S. A., John, E. M., Hayes, R. B., Pharoah, P. D. P., Pashayan, N., Khaw, K-T., Stanford, J. L., Ostrander, E. A., Signorello, L. B., Thibodeau, S. N., Schaid, D., Maier, C., Vogel, W., Kibel, A. S., Cybulski, C., Lubinski, J., Cannon-Albright, L., Brenner, H., Park, J. Y., Kaneva, R. P., Batra, J., Spurdle, A. B., Clements, J. A., Teixeira, M. R., Dicks, E., Lee, A., Dunning, A. M., Baynes, C., Conroy, D. M., Maranian, M. J., Ahmed, S., Govindasami, K., Guy, M., Wilkinson, R. A., Sawyer, E. J., Morgan, A., Dearnaley, D. P., Horwich, A., Huddart, R. A., Khoo, V. S., Parker, C., Van As, N. J., Woodhouse, C. J., Thompson, A., Dudderidge, T., Ogden, C., Cooper, C. S., Lophatananon, A., Cox, A., Southey, M. C., Hopper, J. L., English, D. R., Aly, M., Adolfsson, J., Xu, J., Zheng, S. L., Yeager, M., Kaaks, R. J., Diver, W. R., Gaudet, M. M., Stern, M. C., Corral, R., Joshi, A. D., Shahabi, A., Wahlfors, T., Tammela, T. L. J., Auvinen, A., Virtamo, J., Klarskov, P., Nordestgaard, B. G., Røder, M. A., Nielsen, S. F., Bojesen, S. E., Siddiq, A., Fitzgerald, L. M., Kolb, S., Kwon, E. M., Karyadi, D. M., Blot, W. J., Zheng, W., Cai, Q., McDonnell, S. K., Rinckleb, A. E., Drake, B., Colditz, G. A., Wokolorczyk, D., Stephenson, R. A., Teerlink, C., Muller, H., Rothenbacher, D., Sellers, T. A., Lin, H-Y. L., Slavov, C., Mitev, V., Lose, F. A., Srinivasan, S., Maia, S., Paulo, P., Lange, E., Cooney, K. A., Antoniou, A. C., Vincent, D., Bacot, F., Tessier, D. C., Kote-Jarai, Z. & Easton, D. F., Apr 2013, In : Nature Genetics. 45, 4, p. 385-391 7 p.

Research output: Contribution to journalArticleResearchpeer-review

Identification of a BRCA2-Specific Modifier Locus at 6p24 Related to Breast Cancer Risk

Gaudet, M. M., Kuchenbaecker, K. B., Vijai, J., Klein, R. J., Kirchhoff, T., McGuffog, L., Barrowdale, D., Dunning, A. M., Lee, A., Dennis, J., Healey, S., Dicks, E., Soucy, P., Sinilnikova, O. M., Pankratz, V. S., Wang, X., Eldridge, R. C., Tessier, D. C., Vincent, D., Bacot, F. & 120 othersHogervorst, F. B. L., Peock, S., Stoppa-Lyonnet, D., kConFab Investigators, Peterlongo, P., Schmutzler, R. K., Nathanson, K. L., Piedmonte, M., Singer, C. F., Thomassen, M., Sokolowska, J., Bronner, M., Hansen, T. V. O., Neuhausen, S. L., Blanco, I., Greene, M. H., Garber, J., Weitzel, J. N., Andrulis, I. L., Goldgar, D. E., D'Andrea, E., Caldes, T., Nevanlinna, H., Osorio, A., van Rensburg, E. J., Arason, A., Rennert, G., van den Ouweland, A. M. W., van der Hout, A. H., Kets, C. M., Aalfs, C. M., Wijnen, J. T., Ausems, M. G. E. M., HeBon, emBRAce, Frost, D., Ellis, S., Fineberg, E., Platte, R., Evans, D. G., Jacobs, C., Adlard, J., Tischkowitz, M., Porteous, M. E., Damiola, F., GEMO Study Collaborators, Golmard, L., Barjhoux, L., Longy, M., Belotti, M., Ferrer, S. F., Mazoyer, S., Spurdle, A. B., Manoukian, S., Barile, M., Genuardi, M., Arnold, N., Meindl, A., Sutter, C., Wappenschmidt, B., Domchek, S. M., Pfeiler, G., Friedman, E., Jensen, U. B., Robson, M., Shah, S., Lazaro, C., Mai, P. L., Benitez, J., Southey, M. C., Schmidt, M. K., Fasching, P. A., Peto, J., Humphreys, M. K., Wang, Q., Michailidou, K., Sawyer, E. J., Burwinkel, B., Guénel, P., Bojesen, S. E., Milne, R. L., Brenner, H., Lochmann, M., Brauch, H., Ko, Y. D., Baisch, C., Fischer, H. P., Bruening, T., Pesch, B., Rabstein, S., Spickenheuer, A., Aittomäki, K., Dörk, T., Margolin, S., Mannermaa, A., Lambrechts, D., Chang-Claude, J., Radice, P., Giles, G. G., Haiman, C. A., Winqvist, R., Devillee, P., García-Closas, M., Schoof, N., Hooning, M. J., Cox, A., Pharoah, P. D. P., Jakubowska, A., Orr, N., González-Neira, A., Pita, G., Alonso, M. R., Hall, P., Couch, F. J., Simard, J., Altshuler, D., Easton, D. F., Chenevix-Trench, G., Antoniou, A. C. & Offit, K., 1 Jan 2013, In : PLoS Genetics. 9, 3, 15 p., e1003173.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
File

Large-scale genotyping identifies 41 new loci associated with breast cancer risk

Michailidou, K., Hall, P., Gonzalez-Neira, A., Ghoussaini, M., Dennis, J., Milne, R. L., Schmidt, M. K., Chang-Claude, J., Bojesen, S. E., Bolla, M. K., Wang, Q., Dicks, E., Lee, A., Turnbull, C., Rahman, N., Fletcher, O., Peto, J., Gibson, L., Dos Santos Silva, I., Nevanlinna, H. & 199 othersMuranen, T. A., Aittomäki, K., Blomqvist, C., Czene, K., Irwanto, A. K., Liu, J., Waisfisz, Q., Meijers-Heijboer, H., Adank, M., Van Der Luijt, R. B., Hein, R., Dahmen, N., Beckman, L., Meindl, A., Schmutzler, R. K., Müller-Myhsok, B., Lichtner, P., Hopper, J. L., Southey, M. C., Makalic, E., Schmidt, D. F., Uitterlinden, A. G., Hofman, A., Hunter, D. J., Chanock, S. J., Vincent, D., Bacot, F., Tessier, D. C., Canisius, S., Wessels, L. F. A., Haiman, C. A., Shah, M., Luben, R., Brown, J., Luccarini, C., Schoof, N., Humphreys, K., Li, J., Nordestgaard, B. G., Nielsen, S. F., Flyger, H., Couch, F. J., Wang, X., Vachon, C. M., Stevens, K. N., Lambrechts, D., Moisse, M., Paridaens, R., Christiaens, M. R., Rudolph, A., Nickels, S., Flesch-Janys, D., Johnson, N., Aitken, Z., Aaltonen, K., Heikkinen, T., Broeks, A., Veer, L. J. V. T., van der Schoot, C. E., Guénel, P., Truong, T., Laurent-Puig, P., Menegaux, F., Marme, F., Schneeweiss, A., Sohn, C., Burwinkel, B., Zamora, P. M., Perez, J. I. A., Pita, G., Alonso, M. R., Cox, A., Brock, I. W., Cross, S. S., Reed, M. W. R., Sawyer, E. J., Tomlinson, I. P., Kerin, M. J., Miller, N., Henderson, B. E., Schumacher, F., Le Marchand, L., Andrulis, I. L., Knight, J. A., Glendon, G., Mulligan, A. M., Lindblom, A., Margolin, S., Hooning, M. J., Hollestelle, A., van den Ouweland, A. M. W., Jager, A., Bui, Q. M., Stone, J. L., Dite, G. S., Apicella, C., Tsimiklis, H., Giles, G. G., Severi, G., Baglietto, L., Fasching, P. A., Haeberle, L., Ekici, A. B., Beckmann, M. W., Brenner, H., Müller, H., Arndt, V., Stegmaier, C., Swerdlow, A. J., Ashworth, A., Orr, N., Jones, M., Figueroa, J. D., Lissowska, J., Brinton, L., Goldberg, M. S., Labrèche, F., Dumont, M., Winqvist, R., Pylkäs, K., Jukkola-Vuorinen, A., Grip, M., Brauch, H., Hamann, U., Brüning, T., Radice, P., Peterlongo, P., Manoukian, S., Bonanni, B., Devilee, P., Tollenaar, R. A. E. M., Seynaeve, C., Van Asperen, C. J., Jakubowska, A., Lubinski, J., Jaworska, K., Durda, K., Mannermaa, A., Kataja, V., Kosma, V-M., Hartikainen, J. M., Bogdanova, N. V., Antonenkova, N., Dörk, T., Kristensen, V. N., Anton-Culver, H., Slager, S., Toland, A. E., Edge, S., Fostira, F., Kang, D., Yoo, K-Y., Noh, D-Y., Matsuo, K., Ito, H., Iwata, H., Sueta, A., Wu, A. H., Tseng, C-C., Berg, D., Stram, D. O., Shu, X-O., Lu, W., Gao, Y-T., Cai, H., Teo, S-H., Yip, C. H., Phuah, S. Y., Cornes, B. K., Hartman, M., Miao, H., Lim, W. Y., Sng, J. H., Muir, K., Lophatananon, A., Stewart-Brown, S., Siriwanarangsan, P., Shen, C-Y., Hsiung, C-N., Wu, P-E., Ding, S. L., Sangrajrang, S., Gaborieau, V., Brennan, P., McKay, J., Blot, W. J., Signorello, L. B., Cai, Q., Zheng, W., Deming-Halverson, S., Shrubsole, M., Long, J., Simard, J., Garcia-Closas, M., Pharoah, P. D. P., Chenevix-Trench, G., Dunning, A. M., Benitez, J. & Easton, D. F., Apr 2013, In : Nature Genetics. 45, 4, p. 353-361 9 p.

Research output: Contribution to journalArticleResearchpeer-review

Meta-analysis of genome-wide association studies identifies ten loci influencing allergic sensitization

Bonnelykke, K., Matheson, M. C., Pers, T. H., Granell, R., Strachan, D. P., Couto Alves, A., Linneberg, A., Curtin, J. A., Warrington, N. M., Standl, M., Kerkhof, M., Jonsdottir, I., Bukvic, B. K., Kaakinen, M., Sleimann, P., Thorleifsson, G., Thorsteinsdottir, U., Schramm, K., Baltic, S., Kreiner-Moller, E. & 76 othersSimpson, A., Pourcain, B. S., Coin, L., Hui, J., Walters, E. H., Tiesler, C. M. T., Duffy, D., Jones, G., Marks, G. B., Danoy, P., Meszaros, D., Hayden, C., Henders, A. K., Chapman, B., Kemp, A. J., Cheah, F., Southey, M. C., Roberts, M., Tovey, E. R., Giles, G. G., Chung, L. P., Thomas, P. S., Feather, I., Temple, S., Beilby, J., Morrison, S., Johns, D. P., Mitrpant, C., Shelton, B., Jenkins, M., Britton, W. J., Kemp, A. S., Le Souef, P., Hopper, J. L., Leeder, S. R., Musk, B., Martin, N. G., Brown, M. A., Ring, S. M., McArdle, W. L., Price, L., Robertson, C. F., Pekkanen, J., Tang, C., Thiering, E., Montgomery, G. W., Hartikainen, A-L., Dharmage, S. C., Husemoen, L. L., Herder, C., Kemp, J. P., Elliot, P., James, A., Waldenberger, M., Abramson, M. J., Fairfax, B. P., Knight, J. C., Gupta, R., Thompson, P. J., Holt, P., Sly, P., Hirschhorn, J. N., Blekic, M., Weidinger, S., Hakonarsson, H., Stefansson, K., Heinrich, J., Postma, D., Custovic, A., Pennell, C., Jarvelin, M-R., Koppelman, G. H., Timpson, N., Ferreira, M., Bisgaard, H. & Henderson, A. J., 2013, In : Nature Genetics. 45, 8, p. 902 - 906 5 p.

Research output: Contribution to journalArticleResearchpeer-review

Multiple independent variants at the TERT locus are associated with telomere length and risks of breast and ovarian cancer

Bojesen, S. E., Pooley, K. A., Johnatty, S. E., Beesley, J., Michailidou, K., Tyrer, J., Edwards, S. L., Pickett, H. A., Shen, H., Smart, C. E., Hillman, K. M., Mai, P. L., Lawrenson, K., Stutz, M. D., Lu, Y., Karevan, R., Woods, N., Johnston, R. L., French, J. D., Chen, X. & 417 othersWeischer, M., Nielsen, S. F., Maranian, M. J., Ghoussaini, M., Ahmed, S., Baynes, C., Bolla, M., Wang, Q., Dennis, J., McGuffog, L., Barrowdale, D., Lee, A., Healey, S., Lush, M., Tessier, D., Vincent, D., Bacot, F., Vergote, I., Lambrechts, S., Despierre, E., Risch, H. A., Gonzalez-Neira, A., Rossing, M. A., Pita, G., Doherty, J., Alvarez, N., Larson, M., Fridley, B., Schoof, N., Chang-Claude, J., Cicek, M. S., Peto, J., Kalli, K., Broeks, A., Armasu, S., Schmidt, M., Braaf, L., Winterhoff, B., Nevanlinna, H., Konecny, G. E., Lambrechts, D., Rogmann, L., Guenel, P., Teoman, A., Milne, R. L., Garcia, J., Cox, A., Shridhar, V., Burwinkel, B., Marme, F., Hein, R., Sawyer, E. J., Haiman, C. A., Wang-Gohrke, S., Andrulis, I. L., Moysich, K. B., Hopper, J. L., Odunsi, K., Lindblom, A., Giles, G., Brenner, H., Simard, J., Lurie, G., Fasching, P., Carney, M., Radice, P., Wilkens, L., Swerdlow, A., Goodman, M. T., Brauch, H., Garcia-Closas, M., Hillemanns, P., Winqvist, R., Duerst, M., Devilee, P., Runnebaum, I. B., Jakubowska, A., Lubinski, J., Mannermaa, A., Butzow, R., Bogdanova, N., Dork, T., Pelttari, L. M., Zheng, W., Leminen, A., Anton-Culver, H., Bunker, C. H., Kristensen, V., Ness, R. B., Muir, K., Edwards, R., Meindl, A., Heitz, F., Matsuo, K., Du Bois, A., Wu, A. H., Harter, P., Teo, S-H., Schwaab, I., Shu, X-O., Blot, W., Hosono, S., Kang, D., Nakanishi, T., Hartman, M., Yatabe, Y., Hamann, U., Karlan, B., Sangrajrang, S., Kjaer, S. K., Gaborieau, V., Jensen, A., Eccles, D. M., Hogdall, E., Shen, C-Y., Brown, J. B., Woo, Y. L., Shah, M., Azmi, M. A. N., Luben, R., Omar, S. Z., Czene, K., Vierkant, R. A., Nordestgaard, B., Flyger, H., Vachon, C., Olson, J. E., Wang, X., Levine, D., Rudolph, A., Weber, R. P., Flesch-Janys, D., Iversen, E., Nickels, S., Schildkraut, J. M., Silva, I. D. S., Cramer, D., Gibson, L., Terry, K. L., Fletcher, O., Vitonis, A. F., van der Schoot, C. E., Poole, E. M., Hogervorst, F., Tworoger, S. S., Liu, J., Bandera, E., Li, J., Olson, S. H., Humphreys, K., Orlow, I., Blomqvist, C., Rodriguez-Rodriguez, L., Aittomaki, K., Salvesen, H. B., Muranen, T., Wik, E., Brouwers, B., Krakstad, C., Wauters, E., Halle, M., Wildiers, H., Kiemeney, L., Mulot, C., Aben, K. K., Laurent-Puig, P., Altena, A. M., Truong, T., Massuger, L. F. A. G., Benitez, J., Pejovic, T., Perez, J. I. A., Hoatlin, M., Zamora, M. P., Cook, L., Balasubramanian, S. P., Kelemen, L., Schneeweiss, A., Le, N., Sohn, C., Brooks-Wilson, A., Tomlinson, I. P., Kerin, M., Miller, N., Cybulski, C., Henderson, B. E., Menkiszak, J., Schumacher, F., Wentzensen, N., Le Marchand, L., Yang, H. P., Mulligan, A. M., Glendon, G., Engelholm, S. A., Knight, J. A., Hogdall, C., Apicella, C., Gore, M., Tsimiklis, H., Song, H., Southey, M. C., Jager, A., Ouweland, A. M. W. D., Brown, R., Martens, J. W. M., Flanagan, J., Kriege, M., Paul, J., Margolin, S., Siddiqui, N., Severi, G., Whittemore, A. S., Baglietto, L., McGuire, V., Stegmaier, C., Sieh, W., Muller, H., Arndt, V., Labreche, F., Gao, Y-T., Goldberg, M., Yang, G., Dumont, M., McLaughlin, J. R., Hartmann, A., Ekici, A. B., Beckmann, M., Phelan, C. M., Lux, M., Permuth-Wey, J., Peissel, B., Sellers, T. A., Ficarazzi, F., Barile, M., Ziogas, A., Ashworth, A., Gentry-Maharaj, A., Jones, M., Ramus, S. J., Orr, N., Menon, U. N., Pearce, C. L., Bruning, T., Pike, M. C., Ko, Y-D., Lissowska, J., Figueroa, J., Kupryjanczyk, J., Chanock, S., Dansonka-Mieszkowska, A., Jukkola-Vuorinen, A., Rzepecka, I. K., Pylkas, K., Bidzinski, M., Kauppila, S., Hollestelle, A., Seynaeve, C., Tollenaar, R., Durda, K., Jaworska, K., Hartikainen, J., Kosma, V-M., Kataja, V., Antonenkova, N., Long, J., Shrubsole, M., Deming-Halverson, S., Lophatananon, A., Siriwanarangsan, P., Stewart-Brown, S., Ditsch, N., Lichtner, P., Schmutzler, R., Ito, H., Iwata, H., Tajima, K., Tseng, C-C., Stram, D. O., Van Den Berg, D., Yip, C. H., Ikram, M. K., Teh, Y-C., Cai, H., Lu, W., Signorello, L., Cai, Q., Noh, D-Y., Yoo, K-Y., Miao, H., Iau, P. T-C., Teo, Y. Y., McKay, J., Shapiro, C., Ademuyiwa, F., Fountzilas, G., Hsiung, C-N., Yu, J-C., Hou, M-F., Healey, C., Luccarini, C., Peock, S., Stoppa-Lyonnet, D., Peterlongo, P., Rebbeck, T., Piedmonte, M., Singer, C., Friedman, E., Thomassen, M., Offit, K., Hansen, T. W., Neuhausen, S., Szabo, C., Blanco, I., Garber, J., Narod, S. A., Weitzel, J., Montagna, M., Olah, E., Godwin, A., Yannoukakos, D., Goldgar, D., Caldes, T., Imyanitov, E., Tihomirova, L., Arun, B., Campbell, I. G., Mensenkamp, A., van Asperen, C., van Roozendaal, K., Meijers-Heijboer, H., Collee, J. M., Oosterwijk, J., Hooning, M. J., Rookus, M., van der Luijt, R., Os, T. M., Evans, D. G., Frost, D., Fineberg, E., Barwell, J., Walker, L., Kennedy, M. J., Platte, R., Davidson, R., Ellis, S., Cole, T., Paillerets, B. B., Buecher, B., Damiola, F., Faivre, L., Frenay, M., Sinilnikova, O., Caron, O., Giraud, S., Mazoyer, S., Bonadona, V., Caux-Moncoutier, V., Toloczko-Grabarek, A., Gronwald, J., Byrski, T., Spurdle, A. B., Bonanni, B., Zaffaroni, D., Giannini, G., Bernard, L., Dolcetti, R., Manoukian, S., Arnold, N., Engel, C., Deissler, H., Rhiem, K., Niederacher, D., Plendl, H., Sutter, C., Wappenschmidt, B., Borg, A., Melin, B., Rantala, J., Soller, M., Nathanson, K. L., Domchek, S., Rodriguez, G. A., Salani, R., Kaulich, D. G., Tea, M-K., Paluch, S. S., Laitman, Y., Skytte, A-B., Kruse, T., Jensen, U. B., Robson, M., Gerdes, A-M., Ejlertsen, B., Foretova, L., Savage, S., Lester, J., Soucy, P., Kuchenbaecker, K., Olswold, C., Cunningham, J., Slager, S., Pankratz, V., Dicks, E., Lakhani, S., Couch, F. J., Hall, P., Monteiro, A., Gayther, S. A., Pharoah, P. D., Reddel, R., Goode, E. L., Greene, M. E., Easton, D. F., Berchuck, A., Antoniou, A. C., Chenevix-Trench, G. & Dunning, A. M., 2013, In : Nature Genetics. 45, 4, p. 371 - 384 14 p.

Research output: Contribution to journalArticleResearchpeer-review

PIK3CA Activating Mutation in Colorectal Carcinoma: Associations with Molecular Features and Survival

Rosty, C., Young, J. P., Walsh, M. D., Clendenning, M., Sanderson, K., Walters, R. J., Parry, S., Jenkins, M. A., Win, A. K., Southey, M. C., Hopper, J. L., Giles, G. G., Williamson, E. J., English, D. R. & Buchanan, D. D., 13 Jun 2013, In : PLoS ONE. 8, 6, e65479.

Research output: Contribution to journalArticleResearchpeer-review

Open Access

Population-Based Estimate of Prostate Cancer Risk for Carriers of the HOXB13 Missense Mutation G84E

MacInnis, R. J., Severi, G., Baglietto, L., Dowty, J. G., Jenkins, M. A., Southey, M. C., Hopper, J. L. & Giles, G. G., 15 Feb 2013, In : PLoS ONE. 8, 2, e54727.

Research output: Contribution to journalArticleResearchpeer-review

Open Access

Prevalence of PALB2 mutations in Australasian multiple-case breast cancer families

Teo, Z. L., Park, D. J., Provenzano, E., Chatfield, C. A., Odefrey, F. A., Nguyen-Dumont, T., Dowty, J. G., Hopper, J. L., Winship, I., Goldgar, D. E. & Southey, M. C., 28 Feb 2013, In : Breast Cancer Research. 15, 1, 14 p., R17.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
File

Prospective validation of the breast cancer risk prediction model BOADICEA and a batch-mode version BOADICEACentre

MacInnis, R. J., Bickerstaffe, A., Apicella, C., Dite, G. S., Dowty, J. G., Aujard, K., Phillips, K. A., Weideman, P., Lee, A., Terry, M. B., Giles, G. G., Southey, M. C., Antoniou, A. C. & Hopper, J. L., Sep 2013, In : British Journal of Cancer. 109, 5, p. 1296-1301 6 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access

Tamoxifen and risk of contralateral breast cancer for BRCA1 and BRCA2 mutation carriers

Phillips, K. A., Milne, R. L., Rookus, M. A., Daly, M. B., Antoniou, A. C., Peock, S., Frost, D., Easton, D. F., Ellis, S., Friedlander, M. L., Buys, S. S., Andrieu, N., Noguès, C., Stoppa-Lyonnet, D., Bonadona, V., Pujol, P., McLachlan, S. A., John, E. M., Hooning, M. J., Seynaeve, C. & 16 othersTollenaar, R. A. E. M., Goldgar, D. E., Terry, M. B., Caldes, T., Weideman, P. C., Andrulis, I. L., Singer, C. F., Birch, K., Simard, J., Southey, M. C., Olsson, H. L., Jakubowska, A., Olah, E., Gerdes, A. M., Foretova, L. & Hopper, J. L., 1 Sep 2013, In : Journal of Clinical Oncology. 31, 25, p. 3091-3099 9 p.

Research output: Contribution to journalArticleResearchpeer-review

The use of DNA from archival dried blood spots with the Infinium HumanMethylation450 array

Joo, J. H. E., Wong, E. M., Baglietto, L., Jung, C-H., Tsimiklis, H., Park, D. J., Wong, N. C., English, D. R., Hopper, J. L., Severi, G., Giles, G. G. & Southey, M. C., 15 Mar 2013, In : BMC Biotechnology. 13, 23.

Research output: Contribution to journalArticleResearchpeer-review

Open Access

Tumour morphology predicts PALB2 germline mutation status

Teo, Z. L., Provenzano, E., Dite, G. S., Park, D. J., Apicella, C., Sawyer, S. D., James, P. A., Mitchell, B. G., Trainer, A. H., Lindeman, G. J., Shackleton, K., Cicciarelli, L., Buys, S. S., Andrulis, I. L., Mulligan, A. M. A., Glendon, G., John, E. M., Terry, M. B., Daly, T. M., Odefrey, F. A. & 7 othersNguyen-Dumont, T., Giles, G. G., Dowty, J. G., Winship, I., Goldgar, D. E., Hopper, J. L. & Southey, M. C., 9 Jul 2013, In : British Journal of Cancer. 109, 1, p. 154-163 10 p.

Research output: Contribution to journalArticleResearchpeer-review

Using SNP genotypes to improve the discrimination of a simple breast cancer risk prediction model

Dite, G. S., Mahmoodi, M., Bickerstaffe, A., Hammet, F., Macinnis, R. J., Tsimiklis, H., Dowty, J. G., Apicella, C., Phillips, K. A., Giles, G. G., Southey, M. C. & Hopper, J. L., Jun 2013, In : Breast Cancer Research and Treatment. 139, 3, p. 887-896 10 p.

Research output: Contribution to journalArticleResearchpeer-review

Whole Exome Sequencing Suggests Much of Non-BRCA1/BRCA2 Familial Breast Cancer Is Due to Moderate and Low Penetrance Susceptibility Alleles

Gracia-Aznarez, F. J., Fernandez, V., Pita, G., Peterlongo, P., Dominguez, O., de la Hoya, M., Duran, M., Osorio, A., Moreno, L., Gonzalez-Neira, A., Rosa-Rosa, J. M., Sinilnikova, O., Mazoyer, S., Hopper, J., Lazaro, C., Southey, M., Odefrey, F., Manoukian, S., Catucci, I., Caldes, T. & 8 othersLynch, H. T., Hilbers, F. S. M., van Asperen, C. J., Vasen, H. F. A., Goldgar, D., Radice, P., Devilee, P. & Benitez, J., 8 Feb 2013, In : PLoS ONE. 8, 2, 9 p., e55681.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
File
2012

11q13 is a susceptibility locus for hormone receptor positive breast cancer

Lambrechts, D., Truong, T., Justenhoven, C., Humphreys, M. K., Wang, J. S., Hopper, J. L., Dite, G. S., Apicella, C., Southey, M., Schmidt, M. K., Broeks, A., Cornelissen, S., Van Hien, R., Sawyer, E. J., Tomlinson, I. P., Kerin, M., Miller, N., Milne, R. L., Zamora, P. M., Pérez, J. I. A. & 131 othersBenítez, J., Hamann, U., Ko, Y-D., Brüning, T., Chang-Claude, J., Eilber, U., Hein, R., Nickels, S., Flesch-Janys, D., Wang-Gohrke, S., John, E. M., Miron, A., Winqvist, R., Pylkäs, K., Jukkola-Vuorinen, A., Grip, M., Chenevix-Trench, G., Beesley, J., Chen, X., Investigators, K. C. F., Menegaux, F., Cordina-Duverger, E., Shen, C-Y., Yu, J-C., Wu, P-E., Hou, M-F., Andrulis, I. L., Selander, T., Glendon, G., Mulligan, A. M., Anton-Culver, H., Ziogas, A., Muir, K. R., Lophatananon, A., Rattanamongkongul, S., Puttawibul, P., Jones, M., Orr, N., Ashworth, A., Swerdlow, A. J., Severi, G., Baglietto, L., Giles, G., Southey, M., Marmé, F., Schneeweiss, A., Sohn, C., Burwinkel, B., Yesilyurt, B. T., Neven, P., Paridaens, R., Wildiers, H., Brenner, H., Müller, H., Arndt, V., Stegmaier, C., Meindl, A., Schott, S., Bartram, C. R., Schmutzler, R. K., Cox, A., Brock, I. W., Elliott, G., Cross, S. S., Fasching, P. A., Schulz-wendtland, R., Ekici, A. B., Beckmann, M. W., Fletcher, O., Johnson, N., Silva, I. D. S., Peto, J., Nevanlinna, H., Muranen, T. A., Aittomäki, K., Blomqvist, C., Dörk, T., Schürmann, P., Bremer, M., Hillemanns, P., Bogdanova, N. V., Antonenkova, N., Rogov, Y. I., Karstens, J. H., Khusnutdinova, E., Bermisheva, M., Prokofieva, D., Gancev, S., Jakubowska, A., Lubinski, J., Jaworska, K., Durda, K., Nordestgaard, B. G., Bojesen, S. E., Lanng, C., Mannermaa, A., Kataja, V., Kosma, V-M., Hartikainen, J. M., Radice, P., Peterlongo, P., Manoukian, S., Bernard, L., Couch, F. J., Olson, J. E., Wang, X., Fredericksen, Z., Alnæs, G. G., Kristensen, V., Børresen-Dale, A. L., Devilee, P., Tollenaar, R. A. E. M., Seynaeve, C. M., Hooning, M. J., García-Closas, M., Chanock, S. J., Lissowska, J., Sherman, M. E., Hall, P., Liu, J., Czene, K., Kang, D., Yoo, K-Y., Noh, D-Y., Lindblom, A., Margolin, S., Dunning, A. M., Pharoah, P. D. P., Easton, D. F., Guénel, P. & Brauch, H., Jul 2012, In : Human Mutation. 33, 7, p. 1123-1132 10 p.

Research output: Contribution to journalArticleResearchpeer-review

19p13.1 Is a triple-negative-specific breast cancer susceptibility locus

Stevens, K. N., Fredericksen, Z., Vachon, C. M., Wang, X., Margolin, S., Lindblom, A., Nevanlinna, H., Greco, D., Aittomak̈i, K., Blomqvist, C., Chang-Claude, J., Vrieling, A., Flesch-Janys, D., Sinn, H. P., Wang-Gohrke, S., Nickels, S., Brauch, H., Ko, Y-D., Fischer, H-P., Schmutzler, R. K. & 4 othersHopper, J. L., Southey, M. C., Giles, G. G. & McLean, C. A., 1 Apr 2012, In : Cancer Research. 72, 7, p. 1795-1803 9 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
File

9q31.2-rs865686 as a susceptibility locus for estrogen receptor-positive breast cancer: Evidence from the Breast Cancer Association Consortium

Warren, H., Dudbridge, F., Fletcher, O., Orr, N., Johnson, N., Hopper, J. L., Apicella, C., Southey, M. C., Mahmoodi, M., Schmidt, M. K., Broeks, A., Cornelissen, S., Braaf, L. M., Muir, K. R., Lophatananon, A., Chaiwerawattana, A., Wiangnon, S., Fasching, P. A., Beckmann, M. W., Ekici, A. B. & 3 othersGiles, G., McLean, C. A. & Cox, A., Oct 2012, In : Cancer Epidemiology Biomarkers and Prevention. 21, 10, p. 1783-1791 9 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
File

A meta-analysis of genome-wide association studies of breast cancer identifies two novel susceptibility loci at 6q14 and 20q11

Siddiq, A., Couch, F. J., Chen, G. K., Lindström, S., Eccles, D. M., Millikan, R. C., Michailidou, K., Stram, D. O., Beckmann, L., Rhie, S. K., Ambrosone, C. B., Aittomäki, K., Amiano, P., Apicella, C., Baglietto, L., Bandera, E. V., Beckmann, M. W., Berg, C. D., Bernstein, L., Blomqvist, C. & 121 othersBrauch, H., Brinton, L., Bui, Q. M., Buring, J. E., Buys, S. S., Campa, D., Carpenter, J. E., Chasman, D. I., Chang-Claude, J., Chen, C., Clavel-Chapelon, F., Cox, A., Cross, S. S., Czene, K., Deming Halverson, S. L., Diasio, R. B., Ryan Diver, W., Dunning, A. M., Durcan, L., Ekici, A. B., Fasching, P. A., Feigelson, H. S., Fejerman, L., Figueroa, J. D., Fletcher, O., Flesch-Janys, D., Gaudet, M. M., Gerty, S. M., Rodriguez-Gil, J. L., Giles, G. G., Van Gils, C. H., Godwin, A. K., Graham, N. J., Greco, D., Hall, P., Hankinson, S. E., Hartmann, A., Hein, R., Heinz, J., Hoover, R. N., Hopper, J. L., Hu, J. J., Huntsman, S., Ingles, S. A., Irwanto, A. K., Isaacs, C. J. D., Jacobs, K. B., John, E. M., Justenhoven, C., Kaaks, R. J., Kolonel, L. N., Coetzee, G. A., Lathrop, M. G., Marchand, L. L., Lee, A. M., Lee, I-M., Lesnick, T., Lichtner, P., Liu, J., Lund, E. E., Makalic, E., Martin, N. G., McLean, C. A., Meijers-Heijboer, H., Meindl, A., Miron, P., Monroe, K. R., Montgomery, G. W., Müller-Myhsok, B., Nickels, S., Nyante, S. J., Olswold, C., Overvad, K., Palli, D., Park, D. J., Palmer, J. R., Pathak, H., Peto, J., Pharoah, P. D. P., Rahman, N., Rivadeneira, F., Schmidt, D. F., Schmutzler, R. K., Slager, S., Southey, M. C., Stevens, K. N., Sinn, H. P., Press, M. F., Ross, E., Riboli, E. B., Ridker, P. M., Schumacher, F. R., Severi, G., dos Santos Silva, I., Stone, J. L., Sund, M., Tapper, W. J., Thun, M. J., Travis, R. C., Turnbull, C., Uitterlinden, A. G., Waisfisz, Q., Wang, X., Wang, Z., Weaver, J. E., Schulz-Wendtland, R., Wilkens, L. R., Berg, D., Zheng, W., Ziegler, R. G., Ziv, E., Nevanlinna, H., Easton, D. F., Hunter, D. J., Henderson, B. E., Chanock, S. J., Garcia-Closas, M., Kraft, P., Haiman, C. A., Vachon, C. M. & Australian Breast Cancer Tissue Bank Investigators, 2012, In : Human Molecular Genetics. 21, 24, p. 5373-5384 12 p., dds381.

Research output: Contribution to journalArticleResearchpeer-review

Open Access

A nonsynonymous polymorphism in IRS1 modifies risk of developing breast and ovarian cancers in BRCA1 and ovarian cancer in BRCA2 mutation carriers

Ding, Y. C., McGuffog, L., Healey, S., Friedman, E., Laitman, Y., Shimon, S. P., Kaufman, B., for SWE-BRCA, Liljegren, A., Lindblom, A., Olsson, H., Kristoffersson, U., Stenmark-Askmalm, M., Melin, B., Domchek, S. M., Nathanson, K. L., Rebbeck, T. R., Jakubowska, A., Lubinski, J., Jaworska, K. & 144 othersDurda, K., Gronwald, J., Huzarski, T., Cybulski, C., Byrski, T., Osorio, A., Cajal, T. R., Stavropoulou, A. V., Benítez, J., Hamann, U., Rookus, M., Aalfs, C. M., De Lange, J. L., Meijers-Heijboer, H. E. J., Oosterwijk, J. C., Van Asperen, C. J., Gómez García, E. B., Hoogerbrugge, N., Jager, A., Van Der Luijt, R. B., Easton, D. F., Peock, S., Frost, D., Ellis, S. D., Platte, R., Fineberg, E., Evans, D. G., Lalloo, F., Izatt, L., Eeles, R., Adlard, J., Davidson, R., Eccles, D., Cole, T., Cook, J., Brewer, C., Tischkowitz, M., Godwin, A. K., Pathak, H., Stoppa-Lyonnet, D., Sinilnikova, O. M., Mazoyer, S., Barjhoux, L., Léoné, M., Gauthier-Villars, M., Caux-Moncoutier, V., De Pauw, A., Hardouin, A., Berthet, P., Dreyfus, H., Ferrer, S. F., Collonge-Rame, M. A., Sokolowska, J., Buys, S., Daly, M., Miron, A., Terry, M. B., Chung, W., John, E. M., Southey, M., Goldgar, D., Singer, C. F., Tea, M. K. M., Gschwantler-Kaulich, D., Fink-Retter, A., Hansen, T. V. O., Ejlertsen, B., Johannsson, O. T., Offi, K., Sarrel, K., Gaudet, M. M., Vijai, J., Robson, M., Piedmonte, M. R., Andrews, L., Cohn, D., DeMars, L. R., DiSilvestro, P., Rodriguez, G., Toland, A. E., Montagna, M., Agata, S., Imyanitov, E., Isaacs, C., Janavicius, R., Lazaro, C., Blanco, I., Ramus, S. J., Sucheston, L., Karlan, B. Y., Gross, J., Ganz, P. A., Beattie, M. S., Schmutzler, R. K., Wappenschmidt, B., Meindl, A., Arnold, N., Niederacher, D., Preisler-Adams, S., Gadzicki, D., Varon-Mateeva, R., Deissler, H., Gehrig, A., Sutter, C., Kast, K., Nevanlinna, H., Aittomäki, K., Simard, J., for KConFab Investigators, Spurdle, A. B., Beesley, J., Chen, X., Tomlinson, G. E., Weitzel, J., Garber, J. E., Olopade, O. I., Rubinstein, W. S., Tung, N., Blum, J. L., Narod, S. A., Brummel, S., Gillen, D. L., Lindor, N., Fredericksen, Z., Pankratz, V. S., Couch, F. J., Radice, P., Peterlongo, P., Greene, M. H., Loud, J. T., Mai, P. L., Andrulis, I. L., Glendon, G., Ozcelik, H., Gerdes, A. M., Thomassen, M., Jensen, U. B., Skytte, A. B., Caligo, M. A., Lee, A., Chenevix-Trench, G., Antoniou, A. C., Neuhausen, S. L. & on behalf of Consortium of Investigators of Modifiers of BRCA1/2, 1 Aug 2012, In : Cancer Epidemiology Biomarkers and Prevention. 21, 8, p. 1362-1370 9 p.

Research output: Contribution to journalArticleResearchpeer-review

Body size and risk for colorectal cancers showing BRAF mutations or microsatellite instability: A pooled analysis

Hughes, L. A. E., Williamson, E. J., van Engeland, M., Jenkins, M. A., Giles, G. G., Hopper, J. L., Southey, M. C., Young, J. P., Buchanan, D. D., Walsh, M. D., Van Den Brandt, P. A., Alexandra Goldbohm, R., Weijenberg, M. P. & English, D. R., Aug 2012, In : International Journal of Epidemiology. 41, 4, p. 1060-1072 13 p., dys055.

Research output: Contribution to journalArticleResearchpeer-review

Breast cancer prognosis in BRCA1 and BRCA2 mutation carriers: An international prospective breast cancer family registry population-based cohort study

Goodwin, P. J., Phillips, K. A., West, D. W., Ennis, M., Hopper, J. L., John, E. M., O'Malley, F. P., Milne, R. L., Andrulis, I. L., Friedlander, M. L., Southey, M. C., Apicella, C., Giles, G. G. & Longacre, T. A., 1 Jan 2012, In : Journal of Clinical Oncology. 30, 1, p. 19-26 8 p.

Research output: Contribution to journalArticleResearchpeer-review

Breast cancer risk and 6q22.33: Combined results from breast cancer association consortium and consortium of investigators on modifiers of brca1/2

Kirchhoff, T., Offit, K., Gaudet, M. M., Pharoah, P. D. P., Easton, D. F., Antoniou, A. C., McGuffog, L., Humphreys, M. K., Dunning, A. M., Bojesen, S. E., Nordestgaard, B. G., Flyger, H., Kang, D., Yoo, K-Y., Noh, D-Y., Ahn, S. H., Dork, T., Schürmann, P., Karstens, J. H., Hillemanns, P. & 115 othersCouch, F. J., Olson, J. E., Vachon, C. M., Wang, X., Cox, A., Brock, I., Elliott, G., Reed, M. W. R., Burwinkel, B., Meindl, A., Brauch, H., Justenhoven, C., Hamann, U., Ko, Y-D., Fischer, H-P., Brüning, T., Pesch, B., Harth, V., Rabstein, S., Broeks, A., Schmidt, M. K., Van 't Veer, L. J., Braaf, L. M., Johnson, N., Fletcher, O., Gibson, L., Peto, J., Turnbull, C., Seal, S., Renwick, A., Rahman, N., Wu, P-E., Yu, J-C., Hsiung, C-N., Shen, C-Y., Southey, M. C., Hopper, J. L., Hammet, F., van Dorpe, T., Dieudonne, A. S., Hatse, S., Lambrechts, D., Andrulis, I. L., Bogdanova, N., Antonenkova, N., Rogov, J. I., Prokofieva, D., Bermisheva, M., Khusnutdinova, E., Van Asperen, C. J., Tollenaar, R. A. E. M., Hooning, M. J., Devilee, P., Margolin, S., Lindblom, A., Milne, R. L., Arias, J. I., Pilar Zamora, M., Benítez, J., Severi, G., Baglietto, L., Giles, G. G., Chenevix-Trench, G., Spurdle, A. B., Beesley, J., Chen, X., Holland, H., Healey, S., Wang-Gohrke, S., Chang-Claude, J., Mannermaa, A., Kosma, V-M., Kauppinen, J., Kataja, V., Agnarsson, B. A., Caligo, M. A., Godwin, A. K., Nevanlinna, H., Heikkinen, T., Fredericksen, Z., Lindor, N. M., Nathanson, K. L., Domchek, S. M., Loman, N., Karlsson, P., Askmalm, M. S., Melin, B., Von Wachenfeldt, A., Hogervorst, F. B. L., Verheus, M., Rookus, M. A., Seynaeve, C., Oldenburg, R. A., Ligtenberg, M. J., Ausems, M. G. E. M., Aalfs, C. M., Gille, H. J. P., Wijnen, J. T., Gómez García, E. B., Peock, S., Cook, M., Oliver, C. T., Frost, D., Luccarini, C., Pichert, G., Davidson, R., Chu, C., Eccles, D. M., Ong, K. R., Cook, J., Douglas, F., Hodgson, S., Gareth Evans, D., Eeles, R. A. & Gold, B., 29 Jun 2012, In : PLoS ONE. 7, 6, e35706.

Research output: Contribution to journalArticleResearchpeer-review

Open Access

CHEK2*1100delC heterozygosity in women with breast cancer associated with early death, breast cancer-specific death, and increased risk of a second breast cancer

Weischer, M., Nordestgaard, B. G., Pharoah, P. D. P., Bolla, M. K., Nevanlinna, H., Van't Veer, L. J., Garcia-Closas, M., Hopper, J. L., Hall, P., Andrulis, I. L., Devilee, P., Fasching, P. A., Anton-Culver, H., Lambrechts, D., Hooning, M. J., Cox, A., Giles, G. G., Burwinkel, B., Lindblom, A., Couch, F. J. & 49 othersMannermaa, A., Alnæs, G. G., John, E. M., Dörk, T., Flyger, H., Dunning, A. M., Wang, Q., Muranen, T. A., Van Hien, R., Figueroa, J. D., Southey, M. C., Czene, K., Knight, J. A., Tollenaar, R. A. E. M., Beckmann, M. W., Ziogas, A., Christiaens, M. R., Collée, J. M., Reed, M. W. R., Severi, G., Marme, F., Margolin, S., Olson, J. E., Kosma, V-M., Kristensen, V. N., Miron, A., Bogdanova, N., Shah, M., Blomqvist, C., Broeks, A., Sherman, M. E., Phillips, K. A., Li, J., Liu, J., Glendon, G., Seynaeve, C., Ekici, A. B., Leunen, K., Kriege, M., Cross, S. S., Baglietto, L., Sohn, C., Wang, X., Kataja, V., Børresen-Dale, A. L., Meyer, A., Easton, D. F., Schmidt, M. K. & Bojesen, S. E., 10 Dec 2012, In : Journal of Clinical Oncology. 30, 35, p. 4308-4316 9 p.

Research output: Contribution to journalArticleResearchpeer-review

Colorectal and other cancer risks for carriers and noncarriers from families with a DNA mismatch repair gene mutation: A prospective cohort study

Win, A. K., Young, J. P., Lindor, N. M., Tucker, K. M., Ahnen, D. J., Young, G. P., Buchanan, D. D., Clendenning, M., Giles, G. G., Winship, I., Macrae, F. A., Goldblatt, J., Southey, M. C., Arnold, J., Thibodeau, S. N., Gunawardena, S. R., Bapat, B., Baron, J. A., Casey, G., Gallinger, S. & 5 othersLe Marchand, L., Newcomb, P. A., Haile, R. W. C., Hopper, J. L. & Jenkins, M. A., 20 Mar 2012, In : Journal of Clinical Oncology. 30, 9, p. 958-964 7 p.

Research output: Contribution to journalArticleResearchpeer-review

Common breast cancer susceptibility variants in LSP1 and RAD51L1 are associated with mammographic density measures that predict breast cancer risk

Vachon, C. M., Scott, C. G., Fasching, P. A., Hall, P., Tamimi, R. M., Li, J., Stone, J. L., Apicella, C., Odefrey, F., Gierach, G. L., Jud, S. M., Heusinger, K., Beckmann, M. W., Pollan, M., Fernańdez-Navarro, P., Gonzalez-Neira, A., Benitez, J., Van Gils, C. H., Lokate, M., Onland-Moret, N. C. & 56 othersPeeters, P. H. M., Brown, J., Leyland, J., Varghese, J. S., Easton, D. F., Thompson, D. J., Luben, R. N., Warren, R. M. L., Wareham, N. J., Loos, R. J. F., Khaw, K-T., Ursin, G., Lee, E., Gayther, S. A., Ramus, S. J., Eeles, R. A., Leach, M. O., Kwan-Lim, G., Couch, F. J., Giles, G. G., Baglietto, L., Krishnan, K., Southey, M. C., Le Marchand, L., Kolonel, L. N., Woolcott, C., Maskarinec, G., Haiman, C. A., Walker, S. K., Johnson, N., McCormack, V. A., Biong, M., Alnaes, G. I. G., Gram, I. T., Kristensen, V. N., Brøresen-Dale, A. L., Lindstrom̈, S., Hankinson, S. E., Hunter, D. J., Andrulis, I. L., Knight, J. A., Boyd, N. F., Figuero, J. D., Lissowska, J., Wesolowska, E., Peplonska, B., Bukowska, A., Reszka, E., Liu, J. J., Eriksson, L., Czene, K., Audley, T., Wu, A. H., Pankratz, V. S., Hopper, J. L. & Dos-Santos-Silva, I., Jul 2012, In : Cancer Epidemiology Biomarkers and Prevention. 21, 7, p. 1156-1166 11 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access

Common variants at the 19p13.1 and ZNF365 loci are associated with ER subtypes of breast cancer and ovarian cancer risk in BRCA1 and BRCA2 mutation carriers

Couch, F. J., Gaudet, M. M., Antoniou, A. C., Ramus, S. J., Kuchenbaecker, K. B., Soucy, P., Beesley, J., Chen, X., Wang, X., Kirchhoff, T., McGuffog, L., Barrowdale, D., Lee, A., Healey, S., Sinilnikova, O. M., Andrulis, I. L., Ozcelik, H., Mulligan, A. M., Thomassen, M., Gerdes, A. M. & 173 othersJensen, U. B., Skytte, A. B., Kruse, T. A., Caligo, M. A., Von Wachenfeldt, A., Barbany-Bustinza, G., Loman, N., Soller, M., Ehrencrona, H., Karlsson, P., Nathanson, K., Rebbeck, T. R., Domchek, S. M., Jakubowska, A., Lubinski, J., Jaworska, K., Durda, K., Zołwocka, E., Huzarski, T., Byrski, T., Gronwald, J., Cybulski, C., Goŕski, B., Osorio, A., Durań, M., Tejada, M. I., Benitez, J., Hamann, U., Hogervorst, F. B. L., Van Os, T. A., Van Leeuwen, F. E., Meijers-Heijboer, H. E. J., Wijnen, J., Blok, M. J., Kets, M., Hooning, M. J., Oldenburg, R. A., Ausems, M. G. E. M., Peock, S., Frost, D., Ellis, S. D., Platte, R., Fineberg, E., Evans, D. G., Jacobs, C., Eeles, R. A., Adlard, J., Davidson, R., Eccles, D. M., Cole, T., Cook, J., Paterson, J., Brewer, C., Douglas, F., Hodgson, S. V., Morrison, P. J., Walker, L., Porteous, M. E., Kennedy, M. J., Side, L. E., Bove, B., for EMBRACE, Godwin, A. K., Stoppa-Lyonnet, D., for GEMO Study Collaborators, Fassy-Colcombet, M., Castera, L., Cornelis, F., Mazoyer, S., Leóne, M., Boutry-Kryza, N., Bressac-de Paillerets, B., Caron, O., Pujol, P., Coupier, I., Delnatte, C., Akloul, L., Lynch, H. T., Snyder, C. L., Buys, S. S., Daly, M. B., Terry, M. B., Chung, W. K., John, E. M., Miron, A., Southey, M. C., Hopper, J. L., Goldgar, D. E., Singer, C. F., Rappaport, C., Tea, M. K. M., Fink-Retter, A., Hansen, T. V. O., Nielsen, F. C., Arason, A., Vijai, J., Shah, S., Sarrel, K., Robson, M. E., Piedmonte, M., Phillips, K., Basil, J., Rubinstein, W. S., Boggess, J., Wakeley, K., Ewart-Toland, A., Montagna, M., Agata, S., Imyanitov, E. N., Isaacs, C., Janavicius, R., Lazaro, C., Blanco, I., Feliubadalo, L., Brunet, J., Gayther, S. A., Pharoah, P. P. D., Odunsi, K. O., Karlan, B. Y., Walsh, C. S., Olah, E., Teo, S. H., Ganz, P. A., Beattie, M. S., Van Rensburg, E. J., Dorfling, C. M., Diez, O., Kwong, A., Schmutzler, R. K., Wappenschmidt, B., Engel, C., Meindl, A., Ditsch, N., Arnold, N., Heidemann, S., Niederacher, D., Preisler-Adams, S., Gadzicki, D., Varon-Mateeva, R., Deissler, H., Gehrig, A., Sutter, C., Kast, K., Fiebig, B., Heinritz, W., Caldes, T., De La Hoya, M., Muranen, T. A., Nevanlinna, H., Tischkowitz, M. D., Spurdle, A. B., Neuhausen, S. L., Ding, Y. C., Lindor, N. M., Fredericksen, Z., Pankratz, V. S., Peterlongo, P., Manoukian, S., Peissel, B., Zaffaroni, D., Barile, M., Bernard, L., Viel, A., Giannini, G., Varesco, L., Radice, P., Greene, M. H., Mai, P. L., Easton, D. F., Chenevix-Trench, G., Offit, K., Simard, J. & on behalf of the Consortium of Investigators of Modifiers of BRCA1/2, 1 Jan 2012, In : Cancer Epidemiology Biomarkers and Prevention. 21, 4, p. 645-657 13 p.

Research output: Contribution to journalArticleResearchpeer-review

Comparison of 6q25 breast cancer hits from Asian and European genome wide association studies in the Breast Cancer Association consortium (BCAC)

Hein, R., Maranian, M. J., Hopper, J. L., Kapuscinski, M. K., Southey, M. C., Park, D. J., Schmidt, M. K., Broeks, A., Hogervorst, F. B. L., Bueno-de-Mesquit, H. B., Muir, K. R., Lophatananon, A., Rattanamongkongul, S., Puttawibul, P., Fasching, P. A., Hein, A., Ekici, A. B., Beckmann, M. W., Fletcher, O., Johnson, N. & 148 othersdos Santos Silva, I., Peto, J., Sawyer, E. J., Tomlinson, I. P., Kerin, M., Miller, N., Marmee, F., Schneeweiss, A., Sohn, C., Burwinkel, B., Guénel, P., Cordina-Duverger, E., Menegaux, F., Truong, T., Bojesen, S. E., Nordestgaard, B. G., Flyger, H., Milne, R. L., Perez, J. I. A., Zamora, P. M., Benítez, J., Anton-Culver, H., Ziogas, A., Bernstein, L., Clarke, C. A., Brenner, H., Müller, H., Arndt, V., Stegmaier, C., Rahman, N., Seal, S., Turnbull, C., Renwick, A., Meindl, A., Schott, S., Bartram, C. R., Schmutzler, R. K., Brauch, H., Hamann, U., Ko, Y-D., Wang-Gohrke, S., Dörk, T., Schürmann, P., Karstens, J. H., Hillemanns, P., Nevanlinna, H., Heikkinen, T., Aittomäki, K., Blomqvist, C., Bogdanova, N. V., Zalutsky, I. V., Antonenkova, N., Bermisheva, M., Prokovieva, D., Farahtdinova, A., Khusnutdinova, E., Lindblom, A., Margolin, S., Mannermaa, A., Kataja, V., Kosma, V-M., Hartikainen, J., Chen, X., Beesley, J., Lambrechts, D., Zhao, H., Neven, P., Wildiers, H., Nickels, S., Flesch-Janys, D., Radice, P., Peterlongo, P., Manoukian, S., Barile, M., Couch, F. J., Olson, J. E., Wang, X., Fredericksen, Z., Giles, G. G., Baglietto, L., McLean, C. A., Severi, G., Offit, K., Robson, M. E., Gaudet, M. M., Vijai, J., Alnæs, G. G., Kristensen, V., Børresen-Dale, A. L., John, E. M., Miron, A., Winqvist, R., Pylkäs, K., Jukkola-Vuorinen, A., Grip, M., Andrulis, I. L., Knight, J. A., Glendon, G., Mulligan, A. M., Figueroa, J. D., García-Closas, M., Lissowska, J., Sherman, M. E., Hooning, M. J., Martens, J. W. M., Seynaeve, C., Collée, J. M., Hall, P., Humpreys, K., Czene, K., Liu, J., Cox, A., Brock, I. W., Cross, S. S., Reed, M. W. R., Ahmed, S., Ghoussaini, M., Pharoah, P. DP., Kang, D., Yoo, K-Y., Noh, D-Y., Jakubowska, A., Jaworska, K., Durda, K., Złowocka, E., Sangrajrang, S., Gaborieau, V., Brennan, P., McKay, J., Shen, C-Y., Yu, J-C., Hsu, H. M., Hou, M-F., Orr, N., Schoemaker, M., Ashworth, A., Swerdlow, A. J., Trentham-Dietz, A., Newcomb, P. A., Titus, L., Egan, K. M., Chenevix-Trench, G., Antoniou, A. C., Humphreys, M. K., Morrison, J., Chang-Claude, J., Easton, D. F. & Dunning, A. M., 7 Aug 2012, In : PLoS ONE. 7, 8, e42380.

Research output: Contribution to journalArticleResearchpeer-review

Open Access

Evaluation of chromosome 6p22 as a breast cancer risk modifier locus in a follow-up study of BRCA2 mutation carriers

Stevens, K. N., Wang, X., Fredericksen, Z., Pankratz, V. S., Greene, M. H., Andrulis, I. L., Thomassen, M., Caligo, M., Nathanson, K. L., Jakubowska, A., Osorio, A., Hamann, U., Godwin, A. K., Stoppa-Lyonnet, D., Southey, M., Buys, S. S., Singer, C. F., Hansen, T. V. O., Arason, A., Offit, K. & 17 othersPiedmonte, M., Montagna, M., Imyanitov, E., Tihomirova, L., Sucheston, L., Beattie, M., Neuhausen, S. L., Szabo, C. I., Simard, J., Spurdle, A. B., Healey, S., Chen, X., Rebbeck, T. R., Easton, D. F., Chenevix-Trench, G., Antoniou, A. C. & Couch, F. J., 1 Nov 2012, In : Breast Cancer Research and Treatment. 136, 1, p. 295-302 8 p.

Research output: Contribution to journalArticleResearchpeer-review

Genome-wide association analysis identifies three new breast cancer susceptibility loci

Ghoussaini, M., Fletcher, O., Michailidou, K., Turnbull, C., Schmidt, M. K., Dicks, E., Dennis, J., Wang, Q., Humphreys, M. K., Luccarini, C., Baynes, C., Conroy, D. M., Maranian, M. J., Ahmed, S., Driver, K., Johnson, N., Orr, N., Dos Santos Silva, I., Waisfisz, Q., Meijers-Heijboer, H. & 3 othersSouthey, M., Giles, G. G. & McLean, C., Mar 2012, In : Nature Genetics. 44, 3, p. 312-318 7 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
File

High and low mammographic density human breast tissues maintain histological differential in murine tissue engineering chambers

Chew, G. L., Huang, D., Lin, S. J., Huo, C., Blick, T., Henderson, M. A., Hill, P., Cawson, J., Morrison, W. A., Campbell, I. G., Hopper, J. L., Southey, M. C., Haviv, I. & Thompson, E. W., 1 Aug 2012, In : Breast Cancer Research and Treatment. 135, 1, p. 177-187 11 p.

Research output: Contribution to journalArticleResearchpeer-review

Identification of a novel percent mammographic density locus at 12q24

Stevens, K. N., Lindstrom, S., Scott, C. G., Thompson, D., Sellers, T. A., Wang, X., Wang, A., Atkinson, E., Rider, D. N., Eckel-passow, J. E., Varghese, J. S., Audley, T., Brown, J., Leyland, J., Luben, R. N., Warren, R. M. L., Loos, R. J. F., Wareham, N. J., Li, J., Hall, P. & 34 othersLiu, J., Eriksson, L., Czene, K., Olson, J. E., Shane pankratz, V., Fredericksen, Z., Diasio, R. B., Lee, A. M., Heit, J. A., Deandrade, M., Goode, E. L., Vierkant, R. A., Cunningham, J. M., Armasu, S. M., Weinshilboum, R., Fridley, B. L., Batzler, A., Ingle, J. N., Boyd, N. F., Paterson, A. D., Rommens, J., Martin, L. J., Hopper, J. L., Southey, M. C., Stone, J., Apicella, C., Kraft, P., Hankinson, S. E., Hazra, A., Hunter, D. J., Easton, D. F., Couch, F. J., Tamimi, R. M. & Vachon, C. M., 1 Jul 2012, In : Human Molecular Genetics. 21, 14, p. 3299-3305 7 p., dds158.

Research output: Contribution to journalArticleResearchpeer-review

Identification of fifteen novel germline variants in the BRCA1 3′UTR reveals a variant in a breast cancer case that introduces a functional miR-103 target site

Brewster, B. L., Rossiello, F., French, J. D., Edwards, S. L., Wong, M., Wronski, A., Whiley, P., Waddell, N., Chen, X., Bove, B., KconFab, Hopper, J. L., John, E. M., Andrulis, I., Daly, M., Volorio, S., Bernard, L., Peissel, B., Manoukian, S., Barile, M. & 8 othersPizzamiglio, S., Verderio, P., Spurdle, A. B., Radice, P., Godwin, A. K., Southey, M. C., Brown, M. A. & Peterlongo, P., 1 Dec 2012, In : Human Mutation. 33, 12, p. 1665-1675 11 p.

Research output: Contribution to journalArticleResearchpeer-review

Interleukin-6 promoter variants, prostate cancer risk, and survival

Tindall, E. A., Severi, G., Hoang, H. N., Southey, M. C., English, D. R., Hopper, J. L., Giles, G. G. & Hayes, V. M., 1 Dec 2012, In : Prostate. 72, 16, p. 1701-1707 7 p.

Research output: Contribution to journalArticleResearchpeer-review

Mammographic breast density and breast cancer: Evidence of a shared genetic basis

Varghese, J. S., Thompson, D. J., Michailidou, K., Lindström, S., Turnbull, C., Brown, J., Leyland, J., Warren, R. M. L., Luben, R. N., Loos, R. J., Wareham, N. J., Rommens, J., Paterson, A. D., Martin, L. J., Vachon, C. M., Scott, C. G., Atkinson, E. J., Couch, F. J., Apicella, C., Southey, M. C. & 10 othersStone, J., Li, J., Eriksson, L., Czene, K., Boyd, N. F., Hall, P., Hopper, J. L., Tamimi, R. M., Rahman, N. & Easton, D. F., 15 Mar 2012, In : Cancer Research. 72, 6, p. 1478-1484 7 p.

Research output: Contribution to journalArticleResearchpeer-review

Ovarian cancer susceptibility alleles and risk of ovarian cancer in BRCA1 and BRCA2 mutation carriers

Ramus, S. J., Antoniou, A. C., Kuchenbaecker, K. B., Soucy, P., Beesley, J., Chen, X., McGuffog, L., Sinilnikova, O. M., Healey, S., Barrowdale, D., Lee, A., Thomassen, M., Gerdes, A. M., Kruse, T. A., Jensen, U. B., Skytte, A. B., Caligo, M. A., Liljegren, A., Lindblom, A., Olsson, H. & 171 othersKristoffersson, U., Stenmark-Askmalm, M., Melin, B., Domchek, S. M., Nathanson, K. L., Rebbeck, T. R., Jakubowska, A., Lubinski, J., Jaworska, K., Durda, K., Złowocka, E., Gronwald, J., Huzarski, T., Byrski, T., Cybulski, C., Toloczko-Grabarek, A., Osorio, A., Benitez, J., Duran, M., Tejada, M. I., Hamann, U., Rookus, M., van Leeuwen, F. E., Aalfs, C. M., Meijers-Heijboer, H. E. J., van Asperen, C. J., van Roozendaal, K. E. P., Hoogerbrugge, N., Collée, J. M., Kriege, M., van der Luijt, R. B., HeBon, emBRAce, Peock, S., Frost, D., Ellis, S. D., Platte, R., Fineberg, E., Evans, D. G., Lalloo, F., Jacobs, C., Eeles, R., Adlard, J., Davidson, R., Eccles, D., Cole, T., Cook, J., Paterson, J., Douglas, F., Brewer, C., Hodgson, S., Morrison, P. J., Walker, L., Porteous, M. E., Kennedy, M. J., Pathak, H., Godwin, A. K., Stoppa-Lyonnet, D., Caux-Moncoutier, V., de Pauw, A., Gauthier-Villars, M., Mazoyer, S., Léoné, M., Calender, A., Lasset, C., Bonadona, V., Hardouin, A., Berthet, P., Bignon, Y. J., Uhrhammer, N., Faivre, L., Loustalot, C., GEMO, Buys, S., Daly, M., Miron, A., Terry, M. B., Chung, W. K., John, E. M., Southey, M., Goldgar, D., Singer, C. F., Tea, M. K., Pfeiler, G., Fink-Retter, A., Hansen, T. V. O., Ejlertsen, B., Johannsson, O. T., Offit, K., Kirchhoff, T., Gaudet, M. M., Vijai, J., Robson, M., Piedmonte, M., Phillips, K. A., Van Le, L., Hoffman, J. S., Toland, A. E., Montagna, M., Tognazzo, S., Imyanitov, E., Isaacs, C., Janavicius, R., Lazaro, C., Blanco, I., Tornero, E., Navarro, M., Moysich, K. B., Karlan, B. Y., Gross, J., Olah, E., Vaszko, T., Teo, S. H., Ganz, P. A., Beattie, M. S., Dorfling, C. M., van Rensburg, E. J., Diez, O., Kwong, A., Schmutzler, R. K., Wappenschmidt, B., Engel, C., Meindl, A., Ditsch, N., Arnold, N., Heidemann, S., Niederacher, D., Preisler-Adams, S., Gadzicki, D., Varon-Mateeva, R., Deissler, H., Gehrig, A., Sutter, C., Kast, K., Fiebig, B., Schäfer, D., Caldes, T., de la Hoya, M., Nevanlinna, H., Aittomäki, K., Plante, M., Spurdle, A. B., Neuhausen, S. L., Ding, Y. C., Wang, X., Lindor, N., Fredericksen, Z., Pankratz, V. S., Peterlongo, P., Manoukian, S., Peissel, B., Zaffaroni, D., Bonanni, B., Bernard, L., Dolcetti, R., Papi, L., Ottini, L., Radice, P., Greene, M. H., Mai, P. L., Andrulis, I. L., Glendon, G., Ozcelik, H., OCGN, Pharoah, P. D. P., Gayther, S. A., Simard, J., Easton, D. F., Couch, F. J., Chenevix-Trench, G. & on behalf of the Consortium of Investigators of Modifiers of BRCA1/2 (CIMBA), 1 Apr 2012, In : Human Mutation. 33, 4, p. 690-702 13 p.

Research output: Contribution to journalArticleResearchpeer-review

Pathology of breast and ovarian cancers among BRCA1 and BRCA2 mutation carriers: Results from the consortium of investigators of modifiers of BRCA1/2 (CIMBA)

Mavaddat, N., Barrowdale, D., Andrulis, I. L., Domchek, S. M., Eccles, D., Nevanlinna, H., Ramus, S. J., Spurdle, A., Robson, M., Sherman, M., Mulligan, A. M., Couch, F. J., Engel, C., McGuffog, L., Healey, S., Sinilnikova, O. M., Southey, M. C., Terry, M. B., Goldgar, D., O'Malley, F. & 117 othersJohn, E. M., Janavicius, R., Tihomirova, L., Hansen, T. V. O., Nielsen, F. C., Osorio, A., Stavropoulou, A., Benítez, J., Manoukian, S., Peissel, B., Barile, M., Volorio, S., Pasini, B., Dolcetti, R., Putignano, A. L., Ottini, L., Radice, P., Hamann, U., Rashid, M. U., Hogervorst, F. B., Kriege, M., Van Der Luijt, R. B., for HEBON, Peock, S., Frost, D., Evans, D. G., Brewer, C., Walker, L., Rogers, M. T., Side, L. E., Houghton, C., for EMBRACE, Weaver, J. E., Godwin, A. K., Schmutzler, R. K., Wappenschmidt, B., Meindl, A., Kast, K., Arnold, N., Niederacher, D., Sutter, C., Deissler, H., Gadzicki, D., Preisler-Adams, S., Varon-Mateeva, R., Schönbuchner, I., Gevensleben, H., Stoppa-Lyonnet, D., Belotti, M., Barjhoux, L., for GEMO Study Collaborators, Isaacs, C., Peshkin, B. N., Caldes, T., De Al Hoya, M., Cañadas, C., Heikkinen, T., Heikkilä, P., Aittomäki, K., Blanco, I., Lazaro, C., Brunet, J., Agnarsson, B. A., Arason, A., Barkardottir, R. B., Dumont, M., Simard, J., Montagna, M., Agata, S., D'Andrea, E., Yan, M., Fox, S., Rebbeck, T. R., Rubinstein, W., Tung, N., Garber, J. E., Wang, X., Fredericksen, Z., Pankratz, V. S., Lindor, N. M., Szabo, C., Offit, K., Sakr, R., Gaudet, M. M., Singer, C. F., Tea, M. K., Rappaport, C., Mai, P. L., Greene, M. H., Sokolenko, A., Imyanitov, E., Toland, A. E., Senter, L., Sweet, K., Thomassen, M., Gerdes, A. M., Kruse, T., Caligo, M., Aretini, P., Rantala, J., Von Wachenfeld, A., Henriksson, K., Steele, L., Neuhausen, S. L., Nussbaum, R., Beattie, M., Odunsi, K., Sucheston, L., Gayther, S. A., Nathanson, K., Gross, J., Walsh, C., Karlan, B., Chenevix-Trench, G., Easton, D. F., Antoniou, A. C. & for the Consortium of Investigators of Modifiers of BRCA1/2, 1 Jan 2012, In : Cancer Epidemiology Biomarkers and Prevention. 21, 1, p. 134-147 14 p.

Research output: Contribution to journalArticleResearchpeer-review

PREDICT Plus: Development and validation of a prognostic model for early breast cancer that includes HER2

Wishart, G. C., Bajdik, C. D., Dicks, E., Provenzano, E., Schmidt, M. K., Sherman, M., Greenberg, D. C., Green, A. R., Gelmon, K. A., Kosma, V-M., Olson, J. E., Beckmann, M. W., Winqvist, R., Cross, S. S., Severi, G., Huntsman, D. G., Pylkäs, K., Ellis, I. O., Nielsen, T. O., Giles, G. & 17 othersBlomqvist, C., Fasching, P. A., Couch, F. J., Rakha, E., Foulkes, W. D., Blows, F. M., Bégin, L. R., Van't Veer, L. J., Southey, M., Nevanlinna, H., Mannermaa, A., Cox, A., Cheang, M., Baglietto, L., Caldas, C., Garcia-Closas, M. & Pharoah, P. D. P., 21 Aug 2012, In : British Journal of Cancer. 107, 5, p. 800-807 8 p.

Research output: Contribution to journalArticleResearchpeer-review

RAD51 and Breast Cancer Susceptibility: No Evidence for Rare Variant Association in the Breast Cancer Family Registry Study

Le Calvez-Kelm, F. & Breast Cancer Family Registry, 27 Dec 2012, In : PLoS ONE. 7, 12, 8 p., e52374.

Research output: Contribution to journalArticleResearchpeer-review

Open Access

Rare mutations in XRCC2 increase the risk of breast cancer

Park, D. J., Lesueur, F., Nguyen-Dumont, T., Pertesi, M., Odefrey, F., Hammet, F., Neuhausen, S. L., John, E. M., Andrulis, I. L., Terry, M. B., Daly, T. M., Buys, S. S., Le Calvez-Kelm, F. L., Lonie, A., Pope, B. J., Tsimiklis, H., Voegele, C., Hilbers, F. M., Hoogerbrugge, N., Barroso, A. & 8 othersOsorio, A., Giles, G. G., Devilee, P., Benitez, J., Hopper, J. L., Tavtigian, S. V., Goldgar, D. E. & Southey, M. C., 6 Apr 2012, In : American Journal of Human Genetics. 90, 4, p. 734-739 6 p.

Research output: Contribution to journalArticleResearchpeer-review

Risk factors for uncommon histologic subtypes of breast cancer using centralized pathology review in the Breast Cancer Family Registry

Work, M. E., Andrulis, I. L., John, E. M., Hopper, J. L., Liao, Y., Zhang, F., Knight, J. A., West, D. W., Milne, R. L., Giles, G. G., Longacre, T. A., O'Malley, F. P., Mulligan, A. M., Southey, M. C., Hibshoosh, H. & Terry, M. B., Aug 2012, In : Breast Cancer Research and Treatment. 134, 3, p. 1209-1220 12 p.

Research output: Contribution to journalArticleResearchpeer-review

The role of genetic breast cancer susceptibility variants as prognostic factors

Fasching, P. A., Pharoah, P. D. P., Cox, A., Nevanlinna, H., Bojesen, S. E., Karn, T., Broeks, A., van Leeuwen, F. E., Van't Veer, L. J., Udo, R., Dunning, A. M., Greco, D., Aittomäki, K., Blomqvist, C., Shah, M., Nordestgaard, B. G., Flyger, H., Hopper, J. L., Southey, M. C., Apicella, C. & 78 othersGarcia-Closas, M., Sherman, M. E., Lissowska, J., Seynaeve, C., Huijts, P. E. A., Tollenaar, R. A. E. M., Ziogas, A., Ekici, A. B., Rauh, C., Mannermaa, A., Kataja, V., Kosma, V-M., Hartikainen, J. M., Andrulis, I. L., Ozcelik, H., Mulligan, A. M., Glendon, G., Hall, P., Czene, K., Liu, J., Chang-Claude, J., Wang-Gohrke, S., Eilber, U., Nickels, S., Dörk, T., Schiekel, M., Bremer, M., Park-Simon, T-W., Giles, G. G., Severi, G., Baglietto, L., Hooning, M. J., Martens, J. W. M., Jager, A., Kriege, M., Lindblom, A., Margolin, S., Couch, F. J., Stevens, K. N., Olson, J. E., Kosel, M., Cross, S. S., Balasubramanian, S. P., Reed, M. W. R., Miron, A., John, E. M., Winqvist, R., Pylkäs, K., Jukkola-Vuorinen, A., Kauppila, S., Burwinkel, B., Marme, F., Schneeweiss, A., Sohn, C., Chenevix-Trench, G., Lambrechts, D., Dieudonne, A. S., Hatse, S., Van Limbergen, E., Benitez, J., Milne, R. L., Zamora, P. M., Pérez, J. I. A., Bonanni, B., Peissel, B., Loris, B., Peterlongo, P., Rajaraman, P., Schonfeld, S. J., Anton-Culver, H., Devilee, P., Beckmann, M. W., Slamon, D. J., Phillips, K. A., Figueroa, J. D., Humphreys, M. K., Easton, D. F. & Schmidt, M. K., Sep 2012, In : Human Molecular Genetics. 21, 17, p. 3926-3939 14 p., dds159.

Research output: Contribution to journalArticleResearchpeer-review

Tumour morphology of early-onset breast cancers predicts breast cancer risk for first-degree relatives: the Australian Breast Cancer Family Registry

Dite, G. S., Makalic, E., Schmidt, D. F., Giles, G. G., Hopper, J. L. & Southey, M. C., 28 Aug 2012, In : Breast Cancer Research. 14, 4, R122.

Research output: Contribution to journalArticleResearchpeer-review

Open Access

Using tumour pathology to identify people at high genetic risk of breast and colorectal cancers

Hopper, J. L., Jenkins, M. A., Dowty, J. G., Dite, G. S., Apicella, C., Keogh, L., Win, A. K., Young, J. P., Buchanan, D., Walsh, M. D., Rosty, C., Baglietto, L., Severi, G., Phillips, K. A., Wong, E. M., Dobrovic, A., Waring, P., Winship, I., Ramus, S. J., Giles, G. G. & 1 othersSouthey, M. C., Feb 2012, In : Pathology. 44, 2, p. 89-98 10 p.

Research output: Contribution to journalArticleResearchpeer-review