Melissa Southey


Accepting PhD Students

1990 …2024
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Personal profile


Professor Melissa C. Southey, BSc (Hons, Pathology) PhD (Medicine), GradDip (Law), is a molecular geneticist (FHGSA) and a Founding Fellow of the Faculty of Science, Royal College of Pathologists of Australasia (FFSc, RCPA). She is Chair of Precision Medicine, School of Clinical Sciences at Monash Health, Director of Monash University’s new Biobanking Victoria initiative, based at the Monash Health Translation Precinct and Research Director of the Monash Partners Comprehensive Cancer Consortium.

Professor Southey’s research program has a population-based focus that has been pivotal to the establishment of large genetic epidemiological research resources that are now being utilized to address key questions in cancer research.  Melissa is best known for her work with multiple-case cancer families and heritable risk factors that has provided the evidence base for best practice guidelines for the clinical management of individuals at high risk of the disease.

Professor Southey has led multidisciplinary teams in diagnostic and research settings in Australia and internationally, supported by programmatic awards from the European Commission, the National Institutes of Health (USA), NHMRC and The National Breast Cancer Foundation. She has co-authored more than 520 peer reviewed publications and has been namedin the Clarivate 2018 Highly Cited Researchers, ranking in the top 1% of researchers over the last 10 years.  She actively participates on a number of national and international scientific advisory, governance and editorial bodies.


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External positions

Honorary Professorial Fellow, University of Melbourne

1 Jan 2019 → …

Senior Honorary Research Associate, Cancer Council Victoria

1 Jan 2013 → …

Research area keywords

  • Precision Medicine
  • Oncology
  • Familial Cancer
  • Epidemiology
  • Genomics
  • Biobanking

Network Recent external collaboration on country level. Dive into details by clicking on the dots.

Projects 2015 2024

Research Output 1990 2019

6 Citations (Scopus)

10-year performance of four models of breast cancer risk: a validation study

Terry, M. B., Liao, Y., Whittemore, A. S., Leoce, N., Buchsbaum, R., Zeinomar, N., Dite, G. S., Chung, W. K., Knight, J. A., Southey, M. C., Milne, R. L., Goldgar, D., Giles, G. G., McLachlan, S. A., Friedlander, M. L., Weideman, P. C., Glendon, G., Nesci, S., Andrulis, I. L., John, E. M. & 5 others, Phillips, K. A., Daly, M. B., Buys, S. S., Hopper, J. L. & MacInnis, R. J., 1 Apr 2019, In : The Lancet Oncology. 20, 4, p. 504-517 14 p.

Research output: Contribution to journalArticleResearchpeer-review

2 Citations (Scopus)

Alternative splicing and ACMG-AMP-2015-based classification of PALB2 genetic variants: An ENIGMA report

Lopez-Perolio, I., Leman, R., Behar, R., Lattimore, V., Pearson, J. F., Castéra, L., Martins, A., Vaur, D., Goardon, N., Davy, G., Garre, P., García-Barberán, V., Llovet, P., Pérez-Segura, P., Díaz-Rubio, E., Caldés, T., Hruska, K. S., Hsuan, V., Wu, S., Pesaran, T. & 14 others, Karam, R., Vallon-Christersson, J., Borg, A., Investigators, K., Valenzuela-Palomo, A., Velasco, E. A., Southey, M., Vreeswijk, M. P. G., Devilee, P., Kvist, A., Spurdle, A. B., Walker, L. C., Krieger, S. & De La Hoya, M., 1 Jul 2019, In : Journal of Medical Genetics. 56, 7, p. 453-460 8 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access

Assessing the ProMCol classifier as a prognostic marker for non-metastatic colorectal cancer within the Melbourne Collaborative Cohort Study

Joo, J. E., Jayasekara, H., Wong, E. M., Clendenning, M., Rosty, C., Winship, I. M., Jenkins, M. A., Hopper, J. L., English, D. R., Milne, R. L., Giles, G. G., Southey, M. C. & Buchanan, D. D., 1 Apr 2019, In : Gut. 68, 4, p. 761-762 2 p.

Research output: Contribution to journalLetterOtherpeer-review

1 Citation (Scopus)

Autologous platelet-rich plasma for healing chronic venous leg ulcers: Clinical efficacy and potential mechanisms

Weller, C. D., Gardiner, E. E., Arthur, J. F., Southey, M. & Andrews, R. K., Jun 2019, In : International Wound Journal. 16, 3, p. 788-792 5 p.

Research output: Contribution to journalArticleResearchpeer-review

1 Citation (Scopus)

Benign breast disease increases breast cancer risk independent of underlying familial risk profile: Findings from a Prospective Family Study Cohort

Zeinomar, N., Phillips, K. A., Daly, M. B., Milne, R. L., Dite, G. S., MacInnis, R. J., Liao, Y., Kehm, R. D., Knight, J. A., Southey, M. C., Chung, W. K., Giles, G. G., McLachlan, S. A., Friedlander, M. L., Weideman, P. C., Glendon, G., Nesci, S., kConFab Investigators, Andrulis, I. L., Buys, S. S. & 3 others, John, E. M., Hopper, J. L. & Terry, M. B., 1 Jan 2019, In : International Journal of Cancer. 10 p.

Research output: Contribution to journalArticleResearchpeer-review