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Research Output 2001 2020

2020
1 Citation (Scopus)

Complement C5a induces renal injury in diabetic kidney disease by disrupting mitochondrial metabolic agility

Tan, S. M., Ziemann, M., Thallas-Bonke, V., Snelson, M., Kumar, V., Laskowski, A., Nguyen, T. V., Huynh, K., Clarke, M. V., Libianto, R., Baker, S. T., Skene, A., Power, D. A., MacIsaac, R. J., Henstridge, D. C., Wetsel, R. A., El-Osta, A., Meikle, P. J., Wilson, S. G., Forbes, J. M. & 4 others, Cooper, M. E., Ekinci, E. I., Woodruff, T. M. & Coughlan, M. T., 1 Jan 2020, In : Diabetes. 69, 1, p. 83-98 16 p.

Research output: Contribution to journalArticleResearchpeer-review

2019
12 Citations (Scopus)

Dietary Advanced Glycation End Products: Digestion, Metabolism and Modulation of Gut Microbial Ecology

Snelson, M. & Coughlan, M. T., 22 Jan 2019, In : Nutrients. 11, 2, 15 p., 215.

Research output: Contribution to journalReview ArticleResearchpeer-review

Open Access
File

Globally elevating the AGE clearance receptor, OST48, does not protect against the development of diabetic kidney disease, despite improving insulin secretion

Zhuang, A., Yap, F. Y. T., McCarthy, D., Leung, C., Sourris, K. C., Penfold, S. A., Thallas-Bonke, V., Coughlan, M. T., Schulz, B. L. & Forbes, J. M., 20 Sep 2019, In : Scientific Reports. 9, 1, 10 p., 13664.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
File
3 Citations (Scopus)

Modulation of the Gut Microbiota by Resistant Starch as a Treatment of Chronic Kidney Diseases: Evidence of Efficacy and Mechanistic Insights

Snelson, M., Kellow, N. J. & Coughlan, M., 1 Mar 2019, In : Advances in Nutrition. 10, 2, p. 303-320 18 p.

Research output: Contribution to journalReview ArticleResearchpeer-review

The Devil's in the Detail: The Importance of Specific, Descriptive Language for Reproducibility in Nutrition Science

Snelson, M. & Coughlan, M., 6 Oct 2019, (Accepted/In press) In : Journal of Renal Nutrition. 2 p.

Research output: Contribution to journalLetterOtherpeer-review

The Mitochondria-Targeted Methylglyoxal Sequestering Compound, MitoGamide, Is Cardioprotective in the Diabetic Heart

Tate, M., Higgins, G., De Blasio, M. J., Lindblom, R., Prakoso, D., Deo, M., Kiriazis, H., Park, M., Baeza-Garz, C. D., Caldwell, S. T., Hartley, R. C., Krieg, T., Murphy, M. P. & Coughlan, M., 25 Oct 2019, (Accepted/In press) In : Cardiovascular Drugs and Therapy. 6 p.

Research output: Contribution to journalArticleResearchpeer-review

Methods in renal research: Measurement of autophagic flux in the renal cortex ex vivo

Higgins, G. C., Nguyen, T-V., Ramm, G. & Coughlan, M. T., 1 Sep 2018, In : Nephrology. 23, 9, p. 815-820 6 p.

Research output: Contribution to journalReview ArticleOtherpeer-review

Open Access
File

Nutritional supplements for diabetes

Coughlan, M. T., 1 Dec 2018, In : Journal of Nutrition and Intermediary Metabolism. 14, 1 p.

Research output: Contribution to journalEditorialOtherpeer-review

Open Access
6 Citations (Scopus)

Obesity associated advanced glycation end products within the human uterine cavity adversely impact endometrial function and embryo implantation competence

Antoniotti, G. S., Coughlan, M., Salamonsen, L. A. & Evans, J., 1 Apr 2018, In : Human Reproduction. 33, 4, p. 654-665 12 p.

Research output: Contribution to journalArticleResearchpeer-review

5 Citations (Scopus)

Perinatal exposure to high dietary advanced glycation end products in transgenic NOD8.3 mice leads to pancreatic beta cell dysfunction

Borg, D. J., Yap, F. Y. T., Keshvari, S., Simmons, D. G., Gallo, L. A., Fotheringham, A. K., Zhuang, A., Slattery, R. M., Hasnain, S. Z., Coughlan, M. T., Kantharidis, P. & Forbes, J. M., 2 Jan 2018, In : Islets. 10, 1, p. 10-24 15 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
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4 Citations (Scopus)

RAGE deletion confers renoprotection by reducing responsiveness to transforming growth factor-β and increasing resistance to apoptosis

Hagiwara, S., Sourris, K., Ziemann, M., Tieqiao, W., Mohan, M., McClelland, A. D., Brennan, E., Forbes, J., Coughlan, M., Harcourt, B., Penfold, S., Wang, B., Higgins, G., Pickering, R., El-Osta, A., Thomas, M. C., Cooper, M. E. & Kantharidis, P., 1 May 2018, In : Diabetes. 67, 5, p. 960-973 14 p.

Research output: Contribution to journalArticleResearchpeer-review

5 Citations (Scopus)

Use of readily accessible inflammatory markers to predict diabetic kidney disease

Winter, L., Wong, L. A., Jerums, G., Seah, J. M., Clarke, M., Tan, S. M., Coughlan, M. T., MacIsaac, R. J. & Ekinci, E. I., 22 May 2018, In : Frontiers in Endocrinology. 9, MAY, 17 p., 225.

Research output: Contribution to journalReview ArticleResearchpeer-review

Open Access
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2017
Open Access
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8 Citations (Scopus)

Increased liver AGEs induce hepatic injury mediated through an OST48 pathway

Zhuang, A., Yap, F. Y., Bruce, C., Leung, C., Plan, M. R., Sullivan, M. A., Herath, C. B., McCarthy, D., Sourris, K. C., Kantharidis, P., Coughlan, M. T., Febbraio, M. A., Hodson, M. P., Watt, M. J., Angus, P., Schulz, B. L. & Forbes, J. M., 1 Dec 2017, In : Scientific Reports. 7, 1, 12292.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
File
35 Citations (Scopus)

NADPH oxidase Nox5 accelerates renal injury in diabetic nephropathy

Jha, J. C., Banal, C., Okabe, J., Gray, S. P., Hettige, T., Chow, B. S. M., Thallas-Bonke, V., Vos, L. D., Holterman, C. E., Coughlan, M. T., Power, D. A., Skene, A., Ekinci, E. I., Cooper, M. E., Touyz, R. M., Kennedy, C. R. & Jandeleit-Dahm, K., 1 Oct 2017, In : Diabetes. 66, 10, p. 2691-2703 13 p.

Research output: Contribution to journalArticleResearchpeer-review

14 Citations (Scopus)

Stirring the pot: Can dietary modification alleviate the burden of CKD?

Snelson, M., Clarke, R. E. & Coughlan, M. T., 11 Mar 2017, In : Nutrients. 9, 3, 29 p., 265.

Research output: Contribution to journalReview ArticleResearchpeer-review

Open Access
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2016
4 Citations (Scopus)

Can targeting the incretin pathway dampen RAGE-mediated events in diabetic nephropathy?

Sourris, K. C., Yao, H., Jerums, G., Cooper, M. E., Ekinci, E. I. & Coughlan, M. T., 1 Sep 2016, In : Current Drug Targets. 17, 11, p. 1252-1264 13 p.

Research output: Contribution to journalArticleOtherpeer-review

30 Citations (Scopus)

Challenging the dogma of mitochondrial reactive oxygen species overproduction in diabetic kidney disease

Coughlan, M. T. & Sharma, K., 1 Aug 2016, In : Kidney International. 90, 2, p. 272-279 8 p.

Research output: Contribution to journalReview ArticleResearchpeer-review

13 Citations (Scopus)

Deficiency in apoptosis-inducing factor recapitulates chronic kidney disease via aberrant mitochondrial homeostasis

Coughlan, M. T., Higgins, G. C., Nguyen, T-V., Penfold, S. A., Thallas-Bonke, V., Tan, S. M., Ramm, G., Van Bergen, N. J., Henstridge, D. C., Sourris, K. C., Harcourt, B. E., Trounce, I. A., Robb, P. M., Laskowski, A., McGee, S. L., Genders, A. J., Walder, K., Drew, B. G., Gregorevic, P., Qian, H. & 13 others, Thomas, M. C., Jerums, G., Macisaac, R. J., Skene, A., Power, D. A., Ekinci, E. I., Wijeyeratne, X. W., Gallo, L. A., Herman-Edelstein, M., Ryan, M. T., Cooper, M. E., Thorburn, D. R. & Forbes, J. M., Apr 2016, In : Diabetes. 65, 4, p. 1085-1098 14 p.

Research output: Contribution to journalArticleResearchpeer-review

48 Citations (Scopus)

Dietary advanced glycation end products and risk factors for chronic disease: A systematic review of randomised controlled trials

Clarke, R., Dordevic, A. L., Tan, S. M., Ryan, L. & Coughlan, M. T., 1 Mar 2016, In : Nutrients. 8, 3, 26 p., 125.

Research output: Contribution to journalReview ArticleResearchpeer-review

Open Access
File
28 Citations (Scopus)

Mapping time-course mitochondrial adaptations in the kidney in experimental diabetes

Coughlan, M. T., Nguyen, T. V., Penfold, S. A., Higgins, G. C., Thallas-Bonke, V., Tan, S. M., Van Bergen, N. J., Sourris, K. C., Harcourt, B. E., Thorburn, D. R., Trounce, I. A., Cooper, M. E. & Forbes, J. M., 1 May 2016, In : Clinical Science. 130, 9, p. 711-720 10 p.

Research output: Contribution to journalArticleResearchpeer-review

Mitochondrial Fission/Fusion and Disease

Higgins, G. C. & Coughlan, M. T., 15 Jan 2016, Encyclopedia of Life Sciences. Chichester: John Wiley & Sons, p. 1-7 7 p.

Research output: Chapter in Book/Report/Conference proceedingEncyclopaedia / Dictionary EntryOtherpeer-review

2015
45 Citations (Scopus)

Effect of diet-derived advanced glycation end products on inflammation

Kellow, N. J. & Coughlan, M. T., 2015, In : Nutrition Reviews. 73, 11 (nuv030), p. 737 - 759 23 p.

Research output: Contribution to journalArticleResearchpeer-review

Explainer: what are E numbers and should you avoid them in your diet?

Coughlan, M. T. & Snelson, M., 20 Nov 2015, The Conversation.

Research output: Other contributionOther

Food additives and chronic disease risk: what role do emulsifiers play?

Coughlan, M. T. & Kellow, N. J., 23 Apr 2015, The Conversation.

Research output: Other contributionOther

35 Citations (Scopus)

Targeting mitochondria-and reactive oxygen species-driven pathogenesis in diabetic nephropathy

Lindblom, R. S. J., Higgins, G. C., Coughlan, M. T. & De Haan-Klein, J. B., 2015, In : The Review of Diabetic Studies. 12, 1-2, p. 134-156 23 p.

Research output: Contribution to journalReview ArticleResearchpeer-review

2014
22 Citations (Scopus)

Advanced glycation end products (AGEs) are cross-sectionally associated with insulin secretion in healthy subjects

Forbes, J. M., Sourris, K., De Courten, M. P. J., Dougherty, S. L., Chand, V., Lyons, J., Bertovic, D. A., Coughlan, M. T., Schlaich, M. P., Soldatos, G., Cooper, M. E., Straznicky, N., Kingwell, B. A. & de Courten, B., 2014, In : Amino Acids. 46, 2, p. 321 - 326 6 p.

Research output: Contribution to journalArticleResearchpeer-review

114 Citations (Scopus)

Metabolic benefits of dietary prebiotics in human subjects: a systematic review of randomised controlled trials

Kellow, N., Coughlan, M. T. & Reid, C. M., 2014, In : British Journal of Nutrition. 111, 7, p. 1147 - 1161 15 p.

Research output: Contribution to journalArticleResearchpeer-review

94 Citations (Scopus)

Mitochondrial dysfunction and mitophagy: the beginning and end to diabetic nephropathy?

Higgins, G. C. & Coughlan, M. T., 2014, In : British Journal of Pharmacology. 171, 8, p. 1917 - 1942 26 p.

Research output: Contribution to journalArticleResearchpeer-review

50 Citations (Scopus)

Nox-4 deletion reduces oxidative stress and injury by PKC-α-associated mechanisms in diabetic nephropathy

Thallas-Bonke, V., Jha, J. C., Gray, S. P., Barit, D., Haller, H., Schmidt, H. H. H. W., Coughlan, M. T., Cooper, M. E., Forbes, J. M. & Jandeleit-Dahm, K. A. M., 2014, In : Physiological Reports. 2, 11, 13 p., e12192.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
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18 Citations (Scopus)

Ramipril inhibits AGE-RAGE-induced matrix metalloproteinase-2 activation in experimental diabetic nephropathy

Fukami, K., Yamagishi, S., Coughlan, M. T., Harcourt, B. E., Kantharidis, P., Thallas-Bonke, V., Okuda, S., Cooper, M. E. & Forbes, J. M., 2014, In : Diabetology and Metabolic Syndrome. 6, p. 1 - 9 9 p., 86.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
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2013
32 Citations (Scopus)

Advanced glycation end products augment experimental hepatic fibrosis

Goodwin, M., Herath, C. B., Zhiyuan, J., Leung, C., Coughlan, M. T., Forbes, J. M. & Angus, P. W., 2013, In : Journal of Gastroenterology and Hepatology. 28, 2, p. 369 - 376 8 p.

Research output: Contribution to journalArticleResearchpeer-review

19 Citations (Scopus)

Deficiency in mitochondrial complex I activity due to Ndufs6 gene trap insertion induces renal disease

Forbes, J. M., Ke, B-X., Nguyen, T. V., Henstridge, D. C., Penfold, S. A., Laskowski, A., Sourris, K., Groschner, L. N., Cooper, M., Thorburn, D. R. & Coughlan, M. T., 2013, In : Antioxidants and Redox Signaling. 19, 4, p. 331-343 13 p.

Research output: Contribution to journalArticleResearchpeer-review

Dietary prebiotic supplementation – a potential therapy to reduce advanced glycation?

Kellow, N. J. & Coughlan, M. T., 15 Jul 2013, IMARS Highlights, 8, 4, p. 17-25.

Research output: Contribution to specialist publicationShort ReviewOther

16 Citations (Scopus)

Glucose homeostasis can be differentially modulated by varying individual components of a western diet

Forbes, J. M., Cowan, S. P., Andrikopoulos, S., Morley, A. L., Ward, L. C., Walker, K. Z., Cooper, M. & Coughlan, M. T., 2013, In : Journal of Nutritional Biochemistry. 24, 7, p. 1251 - 1257 7 p.

Research output: Contribution to journalArticleResearchpeer-review

23 Citations (Scopus)

Targeting the AGE-RAGE axis improves renal function in the context of a healthy diet low in advanced glycation end-product content

Thallas-Bonke, V., Coughlan, M. T., Tan, A., Harcourt, B. E., Morgan, P. E., Davies, M. J., Bach, L. A., Cooper, M. & Forbes, J. M., 2013, In : Nephrology. 18, 1, p. 47 - 56 10 p.

Research output: Contribution to journalArticleResearchpeer-review

2012
16 Citations (Scopus)

Advanced glycation end products as environmental risk factors for the development of type 1 diabetes

Yap, F., Kantharidis, P., Coughlan, M. T., Slattery, R. M. & Forbes, J. M., 2012, In : Current Drug Targets. 13, 4, p. 526 - 540 15 p.

Research output: Contribution to journalArticleResearchpeer-review

70 Citations (Scopus)

Ubiquinone (coenzyme Q10) prevents renal mitochondrial dysfunction in an experimental model of type 2 diabetes

Sourris, K. C., Harcourt, B. E., Tang, P., Morley, A., Huynh, K., Penfold, S. A., Coughlan, M. T., Cooper, M. E., Nguyen, T-V., Ritchie, R. H. & Forbes, J. M., 2012, In : Free Radical Biology and Medicine. 52, 3, p. 716 - 723 8 p.

Research output: Contribution to journalArticleResearchpeer-review

2011
89 Citations (Scopus)

Advanced glycation end products are direct modulators of beta-cell function

Coughlan, M. T., Yap, F., Tong, D., Andrikopoulos, S., Gasser, A., Thallas-Bonke, V., Webster, D., Miyazaki, J., Kay, T., Slattery, R., Kaye, D., Drew, B., Kingwell, B., Fourlanos, S., Groop, P-H., Harrison, L., Knip, M. & Forbes, J., 2011, In : Diabetes. 60, 10, p. 2523 - 2532 10 p.

Research output: Contribution to journalArticleResearchpeer-review

28 Citations (Scopus)

Advanced glycation urinary protein-bound biomarkers and severity of diabetic nephropathy in man

Coughlan, M. T., Patel, S. K., Jerums, G., Penfold, S. A., Nguyen, T. V., Sourris, K. C., Panagiotopoulos, S., Srivastava, P. M., Cooper, M. E., Burrell, L. M., MacIsaac, R. J. & Forbes, J. M., Oct 2011, In : American Journal of Nephrology. 34, 4, p. 347-355 9 p.

Research output: Contribution to journalArticleResearchpeer-review

Erratum to: Receptor for advanced glycation end-products (RAGE) provides a link between genetic susceptibility and environmental factors in type 1 diabetes (Diabetologia DOI: 10.1007/s00125-011-2058-z)

Forbes, J. M., Söderlund, J., Yap, F. Y. T., Knip, M., Andrikopoulos, S., Ilonen, J., Simell, O., Veijola, R., Sourris, K. C., Coughlan, M. T., Forsblom, C., Slattery, R., Grey, S. T., Wessman, M., Yamamoto, H., Bierhaus, A., Cooper, M. E. & Groop, P. H., Jun 2011, In : Diabetologia. 54, 6, p. 1586-1587 2 p.

Research output: Contribution to journalComment / DebateOtherpeer-review

226 Citations (Scopus)

MiR-200a prevents renal fibrogenesis through repression of TGF-β2 expression

Wang, B., Koh, P., Winbanks, C., Coughlan, M. T., McClelland, A., Watson, A., Jandeleit-Dahm, K., Burns, W. C., Thomas, M. C., Cooper, M. E. & Kantharidis, P., Jan 2011, In : Diabetes. 60, 1, p. 280-287 8 p.

Research output: Contribution to journalArticleResearchpeer-review

31 Citations (Scopus)

Receptor for advanced glycation end-products (RAGE) provides a link between genetic susceptibility and environmental factors in type 1 diabetes

Forbes, J., Soderlund, J., Yap, F., Knip, M., Andrikopoulos, S., Ilonen, J., Simell, O., Veijola, R., Sourris, K., Coughlan, M. T., Forsblom, C., Slattery, R. M., Grey, S., Wessman, M., Yamamoto, H., Bierhaus, A., Cooper, M. & Groop, P., 2011, In : Diabetologia. 54, 5, p. 1032 - 1042 11 p.

Research output: Contribution to journalArticleResearchpeer-review

Role of oxidative stress in diabetic nephropathy

Forbes, J. M., Coughlan, M. T. & Cooper, M. E., 2011, Advances in Pathogenesis of Diabetic Nephropathy. Prabhakar, S. S. (ed.). Nova Science Publishers, p. 199-218 20 p.

Research output: Chapter in Book/Report/Conference proceedingChapter (Book)Other

69 Citations (Scopus)

Targeted reduction of advanced glycation improves renal function in obesity

Harcourt, B., Sourris, K., Coughlan, M. T., Walker, K., Dougherty, S., Andrikopoulos, S., Morley, A., Thallas-Bonke, V., Chand, V., Penfold, S., De Courten, M. P. J., Thomas, M., Kingwell, B., Bierhaus, A., Cooper, M., de Courten, B. & Forbes, J., 2011, In : Kidney International. 80, 2, p. 190 - 198 9 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
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10 Citations (Scopus)

Temporal increases in urinary carboxymethyllysine correlate with albuminuria development in diabetes

Coughlan, M. T. & Forbes, J. M., 2011, In : American Journal of Nephrology. 34, 1, p. 9 - 17 9 p.

Research output: Contribution to journalArticleResearchpeer-review

2010
52 Citations (Scopus)

Advanced glycation end-products induce vascular dysfunction via resistance to nitric oxide and suppression of endothelial nitric oxide synthase

Soro-Paavonen, A., Zhang, W. Z., Venardos, K., Coughlan, M. T., Harris, E., Tong, D. C. K., Brasacchio, D., Paavonen, K., Chin-Dusting, J., Cooper, M. E., Kaye, D., Thomas, M. C. & Forbes, J. M., Apr 2010, In : Journal of Hypertension. 28, 4, p. 780-788 9 p.

Research output: Contribution to journalArticleResearchpeer-review

61 Citations (Scopus)

Antiatherosclerotic and renoprotective effects of ebselen in the diabetic apolipoprotein E/GPx1-double knockout mouse

Chew, P., Yuen, D., Stefanovic, N., Pete, J., Coughlan, M. T., Jandeleit-Dahm, K., Thomas, M., Rosenfeldt, F., Cooper, M. & De Haan, J. B., 2010, In : Diabetes. 59, 12, p. 3198-3207 10 p.

Research output: Contribution to journalArticleResearchpeer-review