Projects per year
Personal profile
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
Research area keywords
- Clostridium difficile
- mouse models
- pathogenesis
- industry collaboration
- Pre-clinical studies
- gut infections
- AMR
- In vitro and In vivo drug testing
- Therapeutics for gut infections
- infection and immunity
Collaborations and top research areas from the last five years
Recent external collaboration on country/territory level. Dive into details by clicking on the dots or
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Testing the stability and efficacy of the C. difficile clinical colostrum product
Lyras, D. (Primary Chief Investigator (PCI)) & Hutton, M. (Chief Investigator (CI))
28/11/23 → 28/05/26
Project: Research
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Bridge and BridgeTech Industry Fellowship
Hutton, M. (Primary Chief Investigator (PCI))
31/07/23 → 6/11/23
Project: Research
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Developing protocols for testing the efficacy of colostrum against COVID-19
Lyras, D. (Primary Chief Investigator (PCI)) & Hutton, M. (Chief Investigator (CI))
1/10/20 → 31/10/20
Project: Research
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Design, Synthesis, and Evaluation of Cephamycin-Based Antisporulation Agents targeting Clostridioides difficile
Cun, W. Y., Bate, C. E., Srikhanta, Y. N., Hutton, M. L., Webb, C. T., Revitt-Mills, S. A., Lyras, D., McGowan, S., Yu, H., Keller, P. A. & Pyne, S. G., 11 Jan 2024, In: Journal of Medicinal Chemistry. 67, 1, p. 450–466 17 p.Research output: Contribution to journal › Article › Research › peer-review
3 Citations (Scopus) -
Gut Microbial Perturbation and Host Response Induce Redox Pathway Upregulation along the Gut–Liver Axis during Giardiasis in C57BL/6J Mouse Model
Karpe, A. V., Hutton, M. L., Mileto, S. J., James, M. L., Evans, C., Ghodke, A. B., Shah, R. M., Metcalfe, S. S., Liu, J. W., Walsh, T., Lyras, D., Palombo, E. A. & Beale, D. J., Jan 2023, In: International Journal of Molecular Sciences. 24, 2, 17 p., 1636.Research output: Contribution to journal › Article › Research › peer-review
Open Access5 Citations (Scopus) -
A lipoglycopeptide antibiotic for Gram-positive biofilm-related infections
Blaskovich, M. A. T., Hansford, K. A., Butler, M. S., Ramu, S., Kavanagh, A. M., Jarrad, A. M., Prasetyoputri, A., Pitt, M. E., Huang, J. X., Lindahl, F., Ziora, Z. M., Bradford, T., Muldoon, C., Rajaratnam, P., Pelingon, R., Edwards, D. J., Zhang, B., Amado, M., Elliott, A. G. & Zuegg, J. & 33 others, , 14 Sept 2022, In: Science Translational Medicine. 14, 662, 16 p., eabj2381.Research output: Contribution to journal › Article › Research › peer-review
8 Citations (Scopus) -
Bezlotoxumab prevents extraintestinal organ damage induced by Clostridioides difficile infection
Mileto, S. J., Hutton, M. L., Walton, S. L., Das, A., Ioannidis, L. J., Ketagoda, D., Quinn, K. M., Denton, K. M., Hansen, D. S. & Lyras, D., 1 Jan 2022, In: Gut Microbes. 14, 1, 18 p., e2117504.Research output: Contribution to journal › Article › Research › peer-review
Open Access12 Citations (Scopus) -
Cationic peptidomimetic amphiphiles having a n-aryl- or n-naphthyl-1,2,3-triazole core structure targeting clostridioides (Clostridium) difficile: Synthesis, antibacterial evaluation and an in vivo c. difficile infection model
Mahadari, M. K., Jennepalli, S., Tague, A. J., Putsathit, P., Hutton, M. L., Hammer, K. A., Knight, D. R., Riley, T. V., Lyras, D., Keller, P. A. & Pyne, S. G., Aug 2021, In: Antibiotics. 10, 8, 17 p., 913.Research output: Contribution to journal › Article › Research › peer-review
Open Access8 Citations (Scopus)
Prizes
Activities
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PCT/AU2018/051007 (Event)
Yogi Srikhanta (Inventor), Melanie Hutton (Inventor), Milena Awad (Inventor), Julie Singleton (Inventor), Nyssa Drinkwater (Inventor), Sheena McGowan (Inventor) & Dena Lyras (Inventor)
14 Sept 2018Activity: Industry, Government and Philanthropy Engagement and Partnerships › Patents › Patent
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Frontiers in Cellular and Infection Microbiology (Journal)
Melanie Hutton (Editorial board member)
2017 → 2020Activity: Publication peer-review and editorial work types › Editorial responsibility
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Antimicrobial Agents and Chemotherapy (Journal)
Melanie Hutton (Peer reviewer)
2017 → …Activity: Publication peer-review and editorial work types › Peer review responsibility
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Victorian Infection & Immunity Network Young Investigator Symposium 2016
Melanie Hutton (Organiser)
2016 → …Activity: Participating in or organising an event types › Contribution to conference
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Faculty of Medicine, Nursing and Health Sciences Early Career Research Symposium
Melanie Hutton (Organiser)
2015 → …Activity: Participating in or organising an event types › Contribution to conference