Meiling Han


Accepting PhD Students

PhD projects

Project #1: Deciphering the dynamic membrane lipid remodelling in Acinetobacter baumannii and the interaction with membrane-targeting peptides
Project #2: Targeting bacterial metabolic pathways and lipid biogenesis to combat antibiotic resistance
Project #3: Investigating the metabolic perturbations in host microenvironment induced by polymyxins during Pseudomonas aeruginosa infection


Research activity per year

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Personal profile


Dr Meiling Han is an ARC DECRA fellow commencing in 2023 and is doing her research in antimicrobial resistance at Monash Biomedicine Discovery Institute. She completed her PhD in antimicrobial systems pharmacology at Monash Institute of Pharmaceutical Science in 2018. As a 3-year early career researcher, she has supervised 3 PhD, one master’s and one honours students, and secured numerous grants and awards such as the FMNHS Faculty Bridging Postdoctoral Fellowship (2018-2019), the AINSE Early Career Research Grant (2019-2021), and the Rod Rickards Fellowship from the Australian Academy of Sciences (2019). She was also appointed as Vice Chair for the 2023 Gordon Research Seminar in Metabolomics (Italy). Moreover, she has also achieved a productive research output evidenced by 49 peer-reviewed publications (13 first author, 2 corresponding author) in high-impact journals (e.g., Nat Commun, Nat Microbiol, Adv Sci), with a total of >1100 citations (Google Scholar, Sep 2022).

Research interests

Dr Han's research has been focused on the relationship between antimicrobial resistance and the remodelling of membrane lipids in Gram-negative bacteria. Over the past 3 years, she has established an independent research program to characterise the chemical compositions and biological functions of essential bacterial lipids and intracellular metabolites using an integrative metabolomics/lpidomics and biophysical approach (e.g., neutron reflectometry). During this process she has established solid and extensive research skills in pharmacology and biochemistry, in particular, bacterial membrane lipidomics, an emerging field with only a handful of researchers in the world. Her research findings have enriched our knowledge of small molecules within bacteria and will inform the future discovery of much-needed antimicrobials.

Expertise related to UN Sustainable Development Goals

In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):

  • SDG 3 - Good Health and Well-being


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