Personal profile
Biography
Dr Maytham Hussein is a Research Fellow and Team Leader in Anti-infective Pharmacology at the Monash Biomedicine Discovery Institute. His research focuses on antimicrobial pharmacology and multi-omics approaches to understand antibiotic action, tolerance, and resistance. He integrates metabolomics, transcriptomics, proteomics, and systems pharmacology to define cellular adaptations to antibiotic stress, with a particular emphasis on glycopeptide antibiotics and bacterial cell wall biosynthesis. Dr Hussein’s work spans clinical and mechanistic microbiology, aiming to translate omics-derived insights into improved therapeutic strategies and predictive models that strengthen antibiotic efficacy.
Education/Academic qualification
Pharmacy, PhD
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
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SDG 3 Good Health and Well-being
Collaborations and top research areas from the last five years
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A Comparative Review of the Pharmacology of Dalbavancin and Oritavancin for Gram-Positive Infections: Birds of a Feather or Apples and Oranges?
Hussein, M., Barclay, J., Baker, M., Wu, Y., Thombare, V. J., Patil, N., Murthy, A. B., Sharma, R., Rao, G. G., Blaskovich, M. A. T., Li, J. & Velkov, T., 2025, In: Infectious Diseases and Therapy. 14, 10, p. 2221–2246 26 p.Research output: Contribution to journal › Review Article › Research › peer-review
Open Access1 Link opens in a new tab Citation (Scopus) -
Metabolomics-driven prediction of antibiotic resistance: a perspective on pre-genetic intervention
Hussein, M. (Leading Author), Creek, D. J., Baker, M., Rao, G., Li, J. & Velkov, T. (Leading Author), 16 Dec 2025, In: npj antimicrobials & resistance. 3, 1, 6 p., 101.Research output: Contribution to journal › Review Article › Other › peer-review
Open Access -
Erratum: Correction: Synergistic potential of Leu10-teixobactin and cefepime against multidrug-resistant Staphylococcus aureus (BMC microbiology (2024) 24 1 DOI: 10.1186/s12866-024-03577-x)
Koh, A. J. J., Hussein, M., Thombare, V., Crawford, S., Li, J. & Velkov, T., 11 Nov 2024, In: BMC Microbiology. 24, 1, 2 p., 464.Research output: Contribution to journal › Comment / Debate › Other › peer-review
Open Access -
High-level nitrofurantoin resistance in a clinical isolate of Klebsiella pneumoniae: a comparative genomics and metabolomics analysis
Hussein, M., Sun, Z., Hawkey, J., Allobawi, R., Judd, L. M., Carbone, V., Sharma, R., Thombare, V., Baker, M., Rao, G. G., Li, J., Holt, K. E. & Velkov, T., 23 Jan 2024, In: mSystems. 9, 1, 16 p., e00972-23.Research output: Contribution to journal › Article › Research › peer-review
Open Access9 Link opens in a new tab Citations (Scopus) -
Metabolic profiling unveils enhanced antibacterial synergy of polymyxin B and teixobactin against multi-drug resistant Acinetobacter baumannii
Hussein, M., Kang, Z., Neville, S. L., Allobawi, R., Thrombare, V., Koh, A. J. J., Wilksch, J., Crawford, S., Mohammed, M. K., McDevitt, C. A., Baker, M., Rao, G. G., Li, J. & Velkov, T., Dec 2024, In: Scientific Reports. 14, 1, 14 p., 27145.Research output: Contribution to journal › Article › Research › peer-review
Open Access6 Link opens in a new tab Citations (Scopus)