Matthew Piper

Research output

Research output per year 1999 2005 2007 2017 2023 2024

• 65 Article
• 8 Review Article
• 2 Letter
• 1 Chapter (Book)
• 2 More
  • 1 Comment / Debate
  • 1 Editorial

Research output per year

Research output per year

Search results

• 2024

  A defined diet for pre-adult Drosophila melanogaster

  Martelli, F., Quig, A., Mele, S., Lin, J., Fulton, T. L., Wansbrough, M., Barlow, C. K., Schittenhelm, R. B., Johnson, T. K. & Piper, M. D. W., Dec 2024, In: Scientific Reports. 14, 1, 9 p., 6974.

  Research output: Contribution to journal › Article › Research › peer-review

  Open Access
  4 Citations (Scopus)

• Exome-informed formulations of food proteins enhance body growth and feed conversion efficiency in ad libitum-fed mice

  Wu, T., Baatar, D., O' Connor, A. E., O'Bryan, M. K., Stringer, J. M., Hutt, K. J., Malimige Aponso, M., Monro, K., Luo, J., Zhu, Y., Ernst, A., Swindells, E. O. K., Alesi, L. R., Tho Tony Nguyen, N., Piper, M. D. W. & Bennett, L. E., Jan 2024, In: Food Research International. 176, 13 p., 113819.

  Research output: Contribution to journal › Article › Research › peer-review

  Open Access
  1 Citation (Scopus)

• Identifying potential dietary treatments for inherited metabolic disorders using Drosophila nutrigenomics

  Martelli, F., Lin, J., Mele, S., Imlach, W., Kanca, O., Barlow, C. K., Paril, J., Schittenhelm, R. B., Christodoulou, J., Bellen, H. J., Piper, M. D. W. & Johnson, T. K., 26 Mar 2024, In: Cell Reports. 43, 3, 20 p., 113861.

  Research output: Contribution to journal › Article › Research › peer-review

  Open Access
  2 Citations (Scopus)

• Short-term fasting of a single amino acid extends lifespan

  Fulton, T. L., Wansbrough, M. R., Mirth, C. K. & Piper, M. D. W., 2 Feb 2024, In: GeroScience. 46, 4, p. 3607–3615 9 p.

  Research output: Contribution to journal › Article › Research › peer-review

  Open Access
  5 Citations (Scopus)
• 2023

  Ageing impairs protein leveraging in a sex-specific manner in Drosophila melanogaster

  Rushby, H. J., Andrews, Z. B., Piper, M. D. W. & Mirth, C. K., Jan 2023, In: Animal Behaviour. 195, p. 43-51 9 p.

  Research output: Contribution to journal › Article › Research › peer-review
  2 Citations (Scopus)

• Biosynthetic constraints on amino acid synthesis at the base of the food chain may determine their use in higher-order consumer genomes

  Ortega, J. G., Raubenheimer, D., Tyagi, S., Mirth, C. K. & Piper, M. D. W., 13 Feb 2023, In: PLoS Genetics. 19, 2, 21 p., e1010635.

  Research output: Contribution to journal › Article › Research › peer-review

  Open Access
  1 Citation (Scopus)

• Dietary restriction and lifespan: adaptive reallocation or somatic sacrifice?

  Piper, M. D. W., Zanco, B., Sgrò, C. M., Adler, M. I., Mirth, C. K. & Bonduriansky, R., Apr 2023, In: The FEBS Journal. 290, 7, p. 1725-1734 10 p.

  Research output: Contribution to journal › Article › Research › peer-review

  Open Access
  6 Citations (Scopus)

• Drosophila melanogaster females prioritise dietary sterols for producing viable eggs

  Zanco, B., Rapley, L., Johnstone, J. N., Dedman, A., Mirth, C. K., Sgrò, C. M. & Piper, M. D. W., Jan 2023, In: Journal of Insect Physiology. 144, 6 p., 104472.

  Research output: Contribution to journal › Article › Research › peer-review
  5 Citations (Scopus)
• 2022

  Amino acid quality modifies the quantitative availability of protein for reproduction in Drosophila melanogaster

  Ma, C., Mirth, C. K., Hall, M. D. & Piper, M. D. W., May 2022, In: Journal of Insect Physiology. 139, 5 p., 104050.

  Research output: Contribution to journal › Article › Research › peer-review
  15 Citations (Scopus)

• Maternal and paternal sugar consumption interact to modify offspring life history and physiology

  Camilleri, T. L., Piper, M. D. W., Robker, R. L. & Dowling, D. K., May 2022, In: Functional Ecology. 36, 5, p. 1124-1136 13 p.

  Research output: Contribution to journal › Article › Research › peer-review

  Open Access
  5 Citations (Scopus)

• Restricting a single amino acid cross-protects Drosophila melanogaster from nicotine poisoning through mTORC1 and GCN2 signalling

  Fulton, T. L., Mirth, C. K. & Piper, M. D. W., 1 Dec 2022, In: Open Biology. 12, 12, p. 220319 11 p.

  Research output: Contribution to journal › Article › Research › peer-review

  Open Access
  4 Citations (Scopus)

• Target of Rapamycin Drives Unequal Responses to Essential Amino Acid Depletion for Egg Laying in Drosophila Melanogaster

  Alves, A. N., Sgrò, C. M., Piper, M. D. W. & Mirth, C. K., 16 Feb 2022, In: Frontiers in Cell and Developmental Biology. 10, 14 p., 822685.

  Research output: Contribution to journal › Article › Research › peer-review

  Open Access
  7 Citations (Scopus)
• 2021

  A dietary sterol trade-off determines lifespan responses to dietary restriction in Drosophila melanogaster females

  Zanco, B., Mirth, C. K., Sgrò, C. M. & Piper, M. D. W., 26 Jan 2021, In: eLife. 10, 20 p., e62335.

  Research output: Contribution to journal › Article › Research › peer-review

  Open Access
  46 Citations (Scopus)
• 2020

  Effects of short-term dietary protein restriction on blood amino acid levels in young men

  Sjøberg, K. A., Schmoll, D., Piper, M. D. W., Kiens, B. & Rose, A. J., Aug 2020, In: Nutrients. 12, 8, 9 p., 2195.

  Research output: Contribution to journal › Article › Research › peer-review

  Open Access

  File
  5 Citations (Scopus)

• Restriction of essential amino acids dictates the systemic metabolic response to dietary protein dilution

  Yap, Y. W., Rusu, P. M., Chan, A. Y., Fam, B. C., Jungmann, A., Solon-Biet, S. M., Barlow, C. K., Creek, D. J., Huang, E., Schittenhelm, R. B., Morgan, B., Schmoll, D., Kiens, B., Piper, M. D. W., Heikenwälder, M., Simpson, S. J., Bröer, S., Andrikopoulos, S., Muller, O. J. & Rose, A. J., 1 Dec 2020, In: Nature Communications. 11, 1, 13 p., 2894.

  Research output: Contribution to journal › Article › Research › peer-review

  Open Access
  78 Citations (Scopus)

• Sexual dimorphism in the nutritional requirement for adult lifespan in Drosophila melanogaster

  Wu, Q., Yu, G., Cheng, X., Gao, Y., Fan, X., Yang, D., Xie, M., Wang, T., Piper, M. D. W. & Yang, M., Mar 2020, In: Aging Cell. 8 p., e13120.

  Research output: Contribution to journal › Article › Research › peer-review

  Open Access

  File
  32 Citations (Scopus)
• 2019

  Branched-chain amino acids impact health and lifespan indirectly via amino acid balance and appetite control

  Solon-Biet, S. M., Cogger, V. C., Pulpitel, T., Wahl, D., Clark, X., Gregoriou, G. C., Senior, A. M., Wang, Q-P., Brandon, A. E., Perks, R., O’Sullivan, J., Koay, Y. C., Bell-Anderson, K., Kebede, M., Yau, B., Atkinson, C., Svineng, G., Dodgson, T., Wali, J. A., Piper, M. D. W., & 7 othersJuricic, P., Partridge, L., Rose, A. J., Raubenheimer, D., Cooney, G. J., Couteur, D. G. L. & Simpson, S. J., 1 May 2019, In: Nature Metabolism. 1, 5, p. 532-545 14 p.

  Research output: Contribution to journal › Article › Research › peer-review
  236 Citations (Scopus)

• Sex-specific transcriptomic responses to changes in the nutritional environment

  Camus, M. F., Piper, M. D. W. & Reuter, M., 22 Aug 2019, In: eLife. 8, 24 p., e47262.

  Research output: Contribution to journal › Article › Research › peer-review

  Open Access

  File

• Transgenerational Obesity and Healthy Aging in Drosophila

  Camilleri Carter, T-L., Dowling, D. K., Robker, R. & Piper, M., Oct 2019, In: Journals of Gerontology - Series A Biological Sciences and Medical Sciences. 74, 10, p. 1582-1589 8 p.

  Research output: Contribution to journal › Article › Research › peer-review

  Open Access

  File
  9 Citations (Scopus)
• 2018

  Drosophila as a model for ageing

  Piper, M. D. W. & Partridge, L., Sept 2018, In: Biochimica et Biophysica Acta - Molecular Basis of Disease. 1864, 9, p. 2707-2717 11 p.

  Research output: Contribution to journal › Article › Research › peer-review
  177 Citations (Scopus)

• Tissue-specific transcriptome profiling of Drosophila reveals roles for GATA transcription factors in longevity by dietary restriction

  Dobson, A. J., He, X., Blanc, E., Bolukbasi, E., Feseha, Y., Yang, M. & Piper, M. D. W., 1 Dec 2018, In: npj Aging and Mechanisms of Disease. 4, 1, 8 p., 5.

  Research output: Contribution to journal › Article › Research › peer-review

  Open Access

  File
  30 Citations (Scopus)
• 2017

  2,5-Dimethyl-Celecoxib Extends Drosophila Life Span via a Mechanism That Requires Insulin and Target of Rapamycin Signaling

  Wu, Q., Lian, T., Fan, X., Song, C., Gaur, U., Mao, X., Yang, D., Piper, M. D. W. & Yang, M., 1 Oct 2017, In: Journals of Gerontology - Series A Biological Sciences and Medical Sciences. 72, 10, p. 1334-1341 8 p.

  Research output: Contribution to journal › Article › Research › peer-review
  30 Citations (Scopus)

• Both overlapping and independent mechanisms determine how diet and insulin-ligand knockouts extend lifespan of Drosophila melanogaster

  Zandveld, J., van den Heuvel, J., Zwaan, B. J. & Piper, M., 1 Dec 2017, In: npj Aging and Mechanisms of Disease. 3, 1, 4 p., 4.

  Research output: Contribution to journal › Article › Research › peer-review

  Open Access

  File
  7 Citations (Scopus)

• Commensal bacteria and essential amino acids control food choice behavior and reproduction

  Leitão-Gonçalves, R., Carvalho-Santos, Z., Francisco, A. P., Fioreze, G. T., Anjos, M., Baltazar, C., Elias, A. P., Itskov, P. M., Piper, M. D. W. & Ribeiro, C., 25 Apr 2017, In: PLoS Biology. 15, 4, 29 p., e2000862.

  Research output: Contribution to journal › Article › Research › peer-review

  Open Access

  File
  216 Citations (Scopus)

• Matching Dietary Amino Acid Balance to the In Silico-Translated Exome Optimizes Growth and Reproduction without Cost to Lifespan

  Piper, M. D. W., Soultoukis, G. A., Blanc, E., Mesaros, A., Herbert, S. L., Juricic, P., He, X., Atanassov, I., Salmonowicz, H., Yang, M., Simpson, S. J., Ribeiro, C. & Partridge, L., 7 Mar 2017, In: Cell Metabolism. 25, 3, p. 610-621 12 p.

  Research output: Contribution to journal › Article › Research › peer-review

  Open Access

  File
  118 Citations (Scopus)

• Nutritional programming of lifespan by FOXO inhibition on sugar-rich diets

  Dobson, A. J., Ezcurra, M., Flanagan, C. E., Summerfield, A. C., Piper, M., Gems, D. & Alic, N., 10 Jan 2017, In: Cell Reports. 18, 2, p. 299-306 8 p.

  Research output: Contribution to journal › Article › Research › peer-review

  Open Access

  File
  45 Citations (Scopus)

• Sex and genotype effects on nutrient-dependent fitness landscapes in Drosophila melanogaster

  Camus, M. F., Fowler, K., Piper, M. W. D. & Reuter, M., 20 Dec 2017, In: Proceedings of the Royal Society B: Biological Sciences. 284, 1869, 10 p., 20172237.

  Research output: Contribution to journal › Article › Research › peer-review
  28 Citations (Scopus)
• 2016

  Nuclear hormone receptor DHR96 mediates the resistance to xenobiotics but not the increased lifespan of insulin-mutant Drosophila

  Afschar, S., Toivonen, J. M., Hoffmann, J. M., Tain, L. S., Wieser, D., Finlayson, A. J., Driege, Y., Alic, N., Emran, S., Stinn, J., Froehlich, J., Piper, M. & Partridge, L., 2016, In: Proceedings of the National Academy of Sciences of the United States of America. 113, 5, p. 1321-1326 6 p.

  Research output: Contribution to journal › Article › Research › peer-review

  Open Access

  File
  43 Citations (Scopus)
• 2015

  QuantiFly: Robust trainable software for automated Drosophila egg counting

  Waithe, D., Rennert, P., Brostow, G. & Piper, M. D. W., 18 May 2015, In: PLoS ONE. 10, 5, 16 p., e0127659.

  Research output: Contribution to journal › Article › Research › peer-review

  Open Access

  File
  23 Citations (Scopus)
• 2014

  A holidic medium for Drosophila melanogaster

  Piper, M., Blanc, E., Leitao-Goncalves, R., Yang, M., He, X., Linford, N. J., Hoddinott, M. P., Hopfen, C., Soultoukis, G. A., Niemeyer, C., Kerr, F., Pletcher, S., Ribeiro, C. & Partridge, L., 1 Jan 2014, In: Nature Methods. 11, 1, p. 100-105 6 p.

  Research output: Contribution to journal › Article › Research › peer-review

  Open Access

  File
  247 Citations (Scopus)

• Target of rapamycin signalling mediates the lifespan-extending effects of dietary restriction by essential amino acid alteration

  Emran, S., Yang, M., He, X., Zandveld, J. & Piper, M., May 2014, In: Aging. 6, 5, p. 390-398 9 p.

  Research output: Contribution to journal › Article › Research › peer-review

  Open Access

  File
  49 Citations (Scopus)

• Using Doubly-Labeled Water to Measure Energy Expenditure in an Important Small Ectotherm Drosophila melanogaster

  Piper, M., Selman, C., Speakman, J. R. & Partridge, L., 20 Sept 2014, In: Journal of Genetics and Genomics. 41, 9, p. 505-512 8 p.

  Research output: Contribution to journal › Article › Research › peer-review

  Open Access

  File
  4 Citations (Scopus)
• 2013

  Analysing variation in Drosophila aging across independent experimental studies: a meta-analysis of survival data

  Ziehm, M., Piper, M. & Thornton, J., 2013, In: Aging Cell. 12, 5, p. 917 - 922 6 p.

  Research output: Contribution to journal › Article › Research › peer-review

  Open Access
  24 Citations (Scopus)
• 2012

  Detrimental effects of RNAi: a cautionary note on its use in Drosophila ageing studies

  Alic, N., Hoddinott, M. P., Foley, A., Slack, C., Piper, M. & Partridge, L., 2012, In: PLoS ONE. 7, 9, p. 1 - 5 5 p.

  Research output: Contribution to journal › Article › Research › peer-review

  Open Access

  File
  22 Citations (Scopus)
• 2011

  Absence of effects of Sir2 overexpression on lifespan in C. elegans and Drosophila

  Burnett, C., Valentini, S., Cabreiro, F. G., Goss, M., Somogyvari, M., Piper, M., Hoddinott, M. P., Sutphin, G. L., Leko, V., McElwee, J. J., Vazquez-Manrique, R. P., Orfila, A-M., Ackerman, D., Au, C., Vinti, G., Riesen, M., Howard, K., Neri, C., Bedalov, A., Kaeberlein, M., & 3 othersSoti, C., Partridge, L. & Gems, D., 2011, In: Nature. 477, 7365, p. 482 - 485 4 p.

  Research output: Contribution to journal › Article › Research › peer-review
  519 Citations (Scopus)

• Ageing in Drosophila: the role of the insulin/Igf and TOR signalling network

  Partridge, L., Alic, N., Bjedov, I. & Piper, M., 2011, In: Experimental Gerontology. 46, 5, p. 376 - 381 6 p.

  Research output: Contribution to journal › Article › Research › peer-review
  224 Citations (Scopus)

• Dietary restriction and aging: a unifying perspective

  Piper, M., Partridge, L., Raubenheimer, D. & Simpson, S. J., 2011, In: Cell Metabolism. 14, 2, p. 154 - 160 7 p.

  Research output: Contribution to journal › Article › Research › peer-review
  143 Citations (Scopus)

• Dietary restriction delays ageing, but not neuronal dysfunction, in Drosophila models of Alzheimer's disease

  Kerr, F., Augustin, H., Piper, M., Gandy, C., Allen, M., Lovestone, S. & Partridge, L., 2011, In: Neurobiology of Aging. 32, 11, p. 1977 - 1989 13 p.

  Research output: Contribution to journal › Article › Research › peer-review
  37 Citations (Scopus)
• 2010

  Water-independent effects of dietary restriction in Drosophila

  Piper, M., Wong, R., Grandison, R. C., Bass, T. M., Martinez, P. & Partridge, L., 2010, In: Proceedings of the National Academy of Sciences of the United States of America. 107, 14, p. 54 - 56 3 p.

  Research output: Contribution to journal › Article › Research › peer-review
  11 Citations (Scopus)
• 2009

  Amino-acid imbalance explains extension of lifespan by dietary restriction in Drosophila

  Grandison, R. C., Piper, M. & Partridge, L., 2009, In: Nature. 462, 7276, p. 1061 - 1064 4 p.

  Research output: Contribution to journal › Article › Research › peer-review
  626 Citations (Scopus)

• Chemical changes in aging Drosophila melanogaster

  Iqbal, A., Piper, M., Faragher, R. G. A., Naughton, D., Partridge, L. & Ostler, E., 2009, In: Age. 31, 4, p. 343 - 351 9 p.

  Research output: Contribution to journal › Article › Research › peer-review
  4 Citations (Scopus)

• Effect of a standardized dietary restriction protocol on multiple laboratory strains of Drosophila melanogaster

  Grandison, R. C., Wong, R., Bass, T. M., Partridge, L. & Piper, M., 2009, In: PLoS ONE. 4, 1, p. 1 - 8 8 p.

  Research output: Contribution to journal › Article › Research › peer-review

  Open Access

  File
  87 Citations (Scopus)

• Quantification of food intake in Drosophila

  Wong, R., Piper, M., Wertheim, B. & Partridge, L., 2009, In: PLoS ONE. 4, 6, p. 1 - 10 10 p.

  Research output: Contribution to journal › Article › Research › peer-review

  Open Access

  File
  206 Citations (Scopus)
• 2008

  Diet and Aging

  Piper, M. D. W. & Bartke, A., 6 Aug 2008, In: Cell Metabolism. 8, 2, p. 99-104 6 p.

  Research output: Contribution to journal › Article › Research › peer-review
  189 Citations (Scopus)

• Evidence for lifespan extension and delayed age-related biomarkers in insulin receptor substrate 1 null mice

  Selman, C., Lingard, S., Choudhury, A. I., Batterham, R. L., Claret, M., Clements, M., Ramadani, F., Okkenhaug, K., Schuster, E., Blanc, E., Piper, M. D., Al-Qassab, H., Speakman, J. R., Carmignac, D., Robinson, I. C. A., Thornton, J. M., Gems, D., Partridge, L. & Withers, D. J., Mar 2008, In: The FASEB Journal. 22, 3, p. 807-818 12 p.

  Research output: Contribution to journal › Article › Research › peer-review
  442 Citations (Scopus)

• Separating cause from effect: How does insulin/IGF signalling control lifespan in worms, flies and mice?

  Piper, M. D. W., Selman, C., McElwee, J. J. & Partridge, L., Feb 2008, In: Journal of Internal Medicine. 263, 2, p. 179-191 13 p.

  Research output: Contribution to journal › Article › Research › peer-review
  125 Citations (Scopus)
• 2007

  Evolutionary conservation of regulated longevity assurance mechanisms

  McElwee, J. J., Schuster, E., Blanc, E., Piper, M. D., Thomas, J. H., Patel, D. S., Selman, C., Withers, D. J., Thornton, J. M., Partridge, L. & Gems, D., 5 Jul 2007, In: Genome Biology. 8, 7, R132.

  Research output: Contribution to journal › Article › Research › peer-review
  164 Citations (Scopus)

• Optimization of dietary restriction protocols in Drosophila

  Bass, T. M., Grandison, R. C., Wong, R., Martinez, P., Partridge, L. & Piper, M. D. W., Oct 2007, In: Journals of Gerontology - Series A Biological Sciences and Medical Sciences. 62, 10, p. 1071-1081 11 p.

  Research output: Contribution to journal › Article › Research › peer-review

  Open Access
  237 Citations (Scopus)

• Transcriptional responses of Saccharomyces cerevisiae to preferred and nonpreferred nitrogen sources in glucose-limited chemostat cultures

  Boer, V. M., Tai, S. L., Vuralhan, Z., Arifin, Y., Walsh, M. C., Piper, M. D. W., De Winde, J. H., Pronk, J. T. & Daran, J. M., Jun 2007, In: FEMS Yeast Research. 7, 4, p. 604-620 17 p.

  Research output: Contribution to journal › Article › Research › peer-review
  79 Citations (Scopus)
• 2006

  Coordinated multitissue transcriptional and plasma metabonomic profiles following acute caloric restriction in mice

  Selman, C., Kerrison, N. D., Cooray, A., Piper, M. D. W., Lingard, S. J., Barton, R. H., Schuster, E. F., Blanc, E., Gems, D., Nicholson, J. K., Thornton, J. M., Partridge, L. & Withers, D. J., 27 Nov 2006, In: Physiological Genomics. 27, 3, p. 187-200 14 p.

  Research output: Contribution to journal › Article › Research › peer-review
  97 Citations (Scopus)