Accepting PhD Students

PhD projects

nutrition and lifelong health in Drosophila.

19992020

Research output per year

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Personal profile

Biography

  • 2001 - PhD in Biochemistry and Molecular Genetics, UNSW, AU
  • 2001-2003 - postdoc, Technical University of Delft, NL
  • 2003-2011 - postdoc, University College London, UK
  • 2011-2016 - Royal Society University Research Fellow, University College London, UK
  • 2016 - present - ARC Future Fellow, Monash University, AU

Research interests

I am interested in how nutrition affects various aspects of fitness and and long-term health. Our model organism of choice is the fruit fly Drosophila melanogaster.

The interaction between an organism, nutrition and its environment is complex. Inevitably, organisms must consume a diet that is not perfectly matched to their requirements. They must therefore implement strategies to alter their ability to seek out, consume, absorb and metabolise various nutrients in a manner that is sensitive to their nutritional history as well as current and perceived future experiences. My work seeks to understand the mechansms by which organisms modulate these traits.

Together, these underpin a range of projects on insect behaviour and physiology. The application of these activities will enable us to use nutrition as a treatment to enhance health and ageing.

Research area keywords

  • nutrition
  • Drosophila
  • ageing
  • fitness
  • dietary restriction

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Projects

Research Output

Amino acid quality modifies the quantitative availability of protein for reproduction in Drosophila melanogaster

Ma, C., Mirth, C. K., Hall, M. D. & Piper, M. D. W., 1 Jan 2020, (Accepted/In press) In : Journal of Insect Physiology. 5 p., 104050.

Research output: Contribution to journalArticleResearchpeer-review

Restriction of essential amino acids dictates the systemic metabolic response to dietary protein dilution

Yap, Y. W., Rusu, P. M., Chan, A. Y., Fam, B. C., Jungmann, A., Solon-Biet, S. M., Barlow, C. K., Creek, D. J., Huang, E., Schittenhelm, R. B., Morgan, B., Schmoll, D., Kiens, B., Piper, M. D. W., Heikenwälder, M., Simpson, S. J., Bröer, S., Andrikopoulos, S., Muller, O. J. & Rose, A. J., 9 Jun 2020, In : Nature Communications. 11, 13 p., 2894.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
File

Sexual dimorphism in the nutritional requirement for adult lifespan in Drosophila melanogaster

Wu, Q., Yu, G., Cheng, X., Gao, Y., Fan, X., Yang, D., Xie, M., Wang, T., Piper, M. D. W. & Yang, M., Mar 2020, In : Aging Cell. 8 p., e13120.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
File

Branched-chain amino acids impact health and lifespan indirectly via amino acid balance and appetite control

Solon-Biet, S. M., Cogger, V. C., Pulpitel, T., Wahl, D., Clark, X., Gregoriou, G. C., Senior, A. M., Wang, Q-P., Brandon, A. E., Perks, R., O’Sullivan, J., Koay, Y. C., Bell-Anderson, K., Kebede, M., Yau, B., Atkinson, C., Svineng, G., Dodgson, T., Wali, J. A., Piper, M. D. W. & 7 others, Juricic, P., Partridge, L., Rose, A. J., Raubenheimer, D., Cooney, G. J., Couteur, D. G. L. & Simpson, S. J., 1 May 2019, In : Nature Metabolism. 1, 5, p. 532-545 14 p.

Research output: Contribution to journalArticleResearchpeer-review

25 Citations (Scopus)

Sex-specific transcriptomic responses to changes in the nutritional environment

Camus, M. F., Piper, M. D. W. & Reuter, M., 22 Aug 2019, In : eLife. 8, 24 p., e47262.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
File