19992022
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Personal profile

Biography

  • 2001 - PhD in Biochemistry and Molecular Genetics, UNSW, AU
  • 2001-2003 - postdoc, Technical University of Delft, NL
  • 2003-2011 - postdoc, University College London, UK
  • 2011-2016 - Royal Society University Research Fellow, University College London, UK
  • 2016 - present - ARC Future Fellow, Monash University, AU

Research interests

I am interested in how nutrition affects various aspects of fitness and and long-term health. Our model organism of choice is the fruit fly Drosophila melanogaster.

The interaction between an organism, nutrition and its environment is complex. Inevitably, organisms must consume a diet that is not perfectly matched to their requirements. They must therefore implement strategies to alter their ability to seek out, consume, absorb and metabolise various nutrients in a manner that is sensitive to their nutritional history as well as current and perceived future experiences. My work seeks to understand the mechansms by which organisms modulate these traits.

Together, these underpin a range of projects on insect behaviour and physiology. The application of these activities will enable us to use nutrition as a treatment to enhance health and ageing.

Keywords

  • nutrition
  • Drosophila
  • ageing
  • fitness
  • dietary restriction

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Projects 2016 2022

Research Output 1999 2019

Branched-chain amino acids impact health and lifespan indirectly via amino acid balance and appetite control

Solon-Biet, S. M., Cogger, V. C., Pulpitel, T., Wahl, D., Clark, X., Gregoriou, G. C., Senior, A. M., Wang, Q-P., Brandon, A. E., Perks, R., O’Sullivan, J., Koay, Y. C., Bell-Anderson, K., Kebede, M., Yau, B., Atkinson, C., Svineng, G., Dodgson, T., Wali, J. A., Piper, M. D. W. & 7 othersJuricic, P., Partridge, L., Rose, A. J., Raubenheimer, D., Cooney, G. J., Couteur, D. G. L. & Simpson, S. J., May 2019, In : Nature Metabolism. 1, 5, p. 532-545 14 p.

Research output: Contribution to journalArticleResearchpeer-review

Turning food into eggs: insights from nutritional biology and developmental physiology of Drosophila

Mirth, C. K., Nogueira Alves, A. & Piper, M. DW., 1 Feb 2019, In : Current Opinion in Insect Science. 31, p. 49-57 9 p.

Research output: Contribution to journalReview ArticleResearchpeer-review

Open Access
File

Drosophila as a model for ageing

Piper, M. D. W. & Partridge, L., Sep 2018, In : Biochimica et Biophysica Acta - Molecular Basis of Disease. 1864, 9, p. 2707-2717 11 p.

Research output: Contribution to journalArticleResearchpeer-review

Tissue-specific transcriptome profiling of Drosophila reveals roles for GATA transcription factors in longevity by dietary restriction

Dobson, A. J., He, X., Blanc, E., Bolukbasi, E., Feseha, Y., Yang, M. & Piper, M. D. W., 1 Dec 2018, In : npj Aging and Mechanisms of Disease. 4, 1, 8 p., 5.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
File

Using mouse and Drosophila models to investigate the mechanistic links between diet, obesity, type II diabetes, and cancer

Warr, C. G., Shaw, K. H., Azim, A., Piper, M. D. W. & Parsons, L. M., 1 Jan 2018, In : International Journal of Molecular Sciences. 19, 12, 16 p., 4110.

Research output: Contribution to journalReview ArticleResearchpeer-review

Open Access
File