Projects per year
Personal profile
Biography
A/Prof McCormack is a cell biologist with extensive experience in iPSC derivation and use for cell therapy, regenerative medicine, cell-based immuno-oncology, transcriptional and epigenetic control of stem cells, oncogene co-operation and genetic evolution.
His previous roles include post-doctoral positions at the MRC Laboratory of Molecular Biology (Cambridge, UK) and the Royal Melbourne Hospital and Laboratory Head positions at Walter and Eliza Hall Institute and Monash University. In 2022 he became Senior Director of iCamuno Biotherapeutics, an innovative startup biotech focussed on iPSC-based cell therapies, and Adjunct Associate Professor at Australian Centre for Blood Diseases, Monash University. His research has led to over 40 publications in high profile journals including Science, New Engl J Med, J Clin Invest and Blood.
Links: https://www.monash.edu/medicine/ccs/blood-disease/research/ipsc-based-cell-therapies
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
Research area keywords
- iPS cell
- Cell therapies
- Transcription factors
- Epigenetics
- Cancer biology
- Regenerative medicine
Collaborations and top research areas from the last five years
Projects
- 3 Finished
-
Targeting homeobox genes in ACute Myeloid Leukaemia
Shields, B. & McCormack, M.
1/01/17 → 31/12/20
Project: Research
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The role of the homeobox transcription factor Hhex in haematopoiesis and leukaemia
11/07/16 → 31/12/18
Project: Research
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Understanding the multistep pathogenesis of T-cell leukaemia
McCormack, M. (Primary Chief Investigator (PCI)) & Majewski, I. J. (Chief Investigator (CI))
National Health and Medical Research Council (NHMRC) (Australia)
11/07/16 → 31/12/19
Project: Research
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Overexpression of Lmo2 initiates T-lymphoblastic leukemia via impaired thymocyte competition
Abdulla, H. D., Alserihi, R., Flensburg, C., Abeysekera, W., Luo, M. X., Gray, D. H. D., Liu, X., Smyth, G. K., Alexander, W. S., Majewski, I. J. & McCormack, M. P., 5 Jun 2023, In: Journal of Experimental Medicine. 220, 6, 24 p., e20212383.Research output: Contribution to journal › Article › Research › peer-review
Open Access4 Citations (Scopus) -
The Haematopoietically-expressed homeobox transcription factor: roles in development, physiology and disease
Jackson, J. T., Nutt, S. L. & McCormack, M. P., 2023, In: Frontiers in Immunology. 14, 17 p., 1197490.Research output: Contribution to journal › Review Article › Research › peer-review
Open Access4 Citations (Scopus) -
T/myeloid MPAL: origin and pathogenesis
McCormack, M. P., 20 Jan 2022, In: Blood. 139, 3, p. 313-315 3 p.Research output: Contribution to journal › Editorial › Other › peer-review
Open Access4 Citations (Scopus) -
T-ALL can evolve to oncogene independence
Abdulla, H., Vo, A., Shields, B. J., Davies, T. J., Jackson, J. T., Alserihi, R., Viney, E. M., Wong, T., Yan, F., Wong, N. C., Demoen, L., Curtis, D. J., Alexander, W. S., Van Vlierberghe, P., Dickins, R. A. & McCormack, M. P., Aug 2021, In: Leukemia. 35, p. 2205–2219 15 p.Research output: Contribution to journal › Article › Research › peer-review
6 Citations (Scopus) -
Androgens stimulate erythropoiesis through the DNA-binding activity of the androgen receptor in non-hematopoietic cells
McManus, J. F., Nguyen, N. Y. N., Davey, R. A., MacLean, H. E., Pomilio, G., McCormack, M. P., Chiu, W. S., Wei, A. H., Zajac, J. D. & Curtis, D. J., Sept 2020, In: European Journal of Haematology. 105, 3, p. 247-254 8 p.Research output: Contribution to journal › Article › Research › peer-review
13 Citations (Scopus)