Research output per year
Research output per year
Personal profile
Biography
Dr Matthew Eramo completed his PhD in the laboratory of Professor Christina Mitchell in 2016, with his PhD and post-doctoral research focussing on the regulation of autophagy and lysosome recycling in the maintenance of skeletal muscle homeostasis. In particular, how dysfunction of these biochemical pathways lead to human muscular dystrophies and myopathies, and their influence on mitochondrial quality control and whole-body metabolism. In 2019, Dr Eramo joined the laboratory of Professor Mike Ryan, and is currently investigating novel proteins involved in maintenance of mitochondrial cristae architecture and how these control mitochondrial structure, dynamics and function.
Ryan Lab website - https://www.monash.edu/discovery-institute/ryan-lab/home
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
Research area keywords
- Biochemistry and Cell Biology
- Mouse models
- Autophagy
- Mitochondrial biology
- Human disease
- Mitochondrial Disease
- Lysosome
- MICOS
- Microscopy
- Mitochondrial cristae
- OXPHOS
- Skeletal muscle
- Metabolism
- Oxidative Stress
- Cellular Signalling
- Muscular Dystrophies/Myopathies
Network
Recent external collaboration on country/territory level. Dive into details by clicking on the dots or
Research output
- 7 Article
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Bidirectional interconversion between PtdIns4P and PtdIns(4,5)P2 is required for autophagic lysosome reformation and protection from skeletal muscle disease
Eramo, M. J., Gurung, R., Mitchell, C. A. & McGrath, M. J., 2021, In: Autophagy. 17, 5, p. 1287-1289 3 p.Research output: Contribution to journal › Article › Research › peer-review
1 Citation (Scopus) -
Defective lysosome reformation during autophagy causes skeletal muscle disease
McGrath, M. J., Eramo, M. J., Gurung, R., Sriratana, A., Gehrig, S. M., Lynch, G. S., Lourdes, S. R., Koentgen, F., Feeney, S. J., Lazarou, M., McLean, C. A. & Mitchell, C. A., 4 Jan 2021, In: Journal of Clinical Investigation. 131, 1, 16 p., e135124.Research output: Contribution to journal › Article › Research › peer-review
Open Access13 Citations (Scopus) -
INPP4B promotes PI3Kα-dependent late endosome formation and Wnt/β-catenin signaling in breast cancer
Rodgers, S. J., Ooms, L. M., Oorschot, V. M. J., Schittenhelm, R. B., Nguyen, E. V., Hamila, S. A., Rynkiewicz, N., Gurung, R., Eramo, M. J., Sriratana, A., Fedele, C. G., Caramia, F., Loi, S., Kerr, G., Abud, H. E., Ramm, G., Papa, A., Ellisdon, A. M., Daly, R. J., McLean, C. A. & 1 others, , 2021, In: Nature Communications. 12, 1, 19 p., 3140.Research output: Contribution to journal › Article › Research › peer-review
Open Access5 Citations (Scopus) -
Skeletal muscle NOX4 is required for adaptive responses that prevent insulin resistance
Xirouchaki, C. E., Jia, Y., McGrath, M. J., Greatorex, S., Tran, M., Merry, T. L., Hong, D., Eramo, M. J., Broome, S. C., Woodhead, J. S. T., D'Souza, R. F., Gallagher, J., Salimova, E., Huang, C., Schittenhelm, R. B., Sadoshima, J., Watt, M. J., Mitchell, C. A. & Tiganis, T., 17 Dec 2021, In: Science Advances. 7, 51, 24 p., eabl4988.Research output: Contribution to journal › Article › Research › peer-review
Open Access -
The 'mitochondrial contact site and cristae organising system' (MICOS) in health and human disease
Eramo, M. J., Lisnyak, V., Formosa, L. E. & Ryan, M. T., Mar 2020, In: The Journal of Biochemistry. 167, 3, p. 243-255 13 p.Research output: Contribution to journal › Article › Research › peer-review
23 Citations (Scopus)