Matthew Belousoff

Mr

20052020
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Research Output 2005 2019

  • 43 Article
  • 2 Chapter (Book)
  • 2 Comment / Debate
  • 2 Review Article
2019

cryoEM-Guided Development of Antibiotics for Drug-Resistant Bacteria

Belousoff, M. J., Venugopal, H., Wright, A., Seoner, S., Stuart, I., Stubenrauch, C., Bamert, R. S., Lupton, D. W. & Lithgow, T., 5 Mar 2019, In : ChemMedChem. 14, 5, p. 527-231 5 p.

Research output: Contribution to journalArticleResearchpeer-review

2018

Delivery of femtolitre droplets using surface acoustic wave based atomisation for cryo-EM grid preparation

Ashtiani, D., Venugopal, H., Belousoff, M., Spicer, B., Mak, J., Neild, A. & de Marco, A., Aug 2018, In : Journal of Structural Biology. 203, 2, p. 94-101 8 p.

Research output: Contribution to journalArticleResearchpeer-review

Macrocycles Bearing Ferrocenyl Pendants and their Electrochemical Properties upon Binding to Divalent Transition Metal Cations

Zeng, Z., Belousoff, M. J., Spiccia, L., Bond, A. M. & Torriero, A. A. J., 2018, In : ChemPlusChem. 83, 7, p. 728-738 11 p.

Research output: Contribution to journalArticleResearchpeer-review

Rapid near-atomic resolution single-particle 3D reconstruction with SIMPLE

Reboul, C. F., Kiesewetter, S., Eager, M., Belousoff, M., Cui, T., De Sterck, H., Elmlund, D. & Elmlund, H., Nov 2018, In : Journal of Structural Biology. 204, 2, p. 172-181 10 p.

Research output: Contribution to journalArticleResearchpeer-review

Structure and membrane topography of the vibrio-type secretin complex from the type 2 secretion system of enteropathogenic Escherichia coli

Hay, I. D., Belousoff, M. J., Dunstan, R. A., Bamert, R. S. & Lithgow, T., 1 Mar 2018, In : Journal of Bacteriology. 200, 5, 15 p., e00521-17.

Research output: Contribution to journalArticleResearchpeer-review

2017

Structural basis for linezolid binding site rearrangement in the Staphylococcus aureus ribosome

Belousoff, M. J., Eyal, Z., Radjainia, M., Ahmed, T., Bamert, R. S., Matzov, D., Bashan, A., Zimmerman, E., Mishra, S., Cameron, D., Elmlund, H., Peleg, A. Y., Bhushan, S., Lithgow, T. & Yonath, A., 9 May 2017, In : mBio. 8, 3, 7 p., e00395-17.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
File

Structural basis for substrate selection by the translocation and assembly module of the β-barrel assembly machinery

Bamert, R. S., Lundquist, K., Hwang, H., Webb, C. T., Shiota, T., Stubenrauch, C. J., Belousoff, M. J., Goode, R. J. A., Schittenhelm, R. B., Zimmerman, R., Jung, M., Gumbart, J. C. & Lithgow, T., 1 Oct 2017, In : Molecular Microbiology. 106, 1, p. 142-156 15 p.

Research output: Contribution to journalArticleResearchpeer-review

Structural basis of type 2 secretion system engagement between the inner and outer bacterial membranes

Hay, I. D., Belousoff, M. J. & Lithgow, T., 17 Oct 2017, In : mBio. 8, 5, 6 p., e01344-17.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
File

The redesign of oxazolidinone antibiotics in response to Staphylococcus aureus

Lupton, D. & Belousoff, M. J., 1 Oct 2017, In : Future Microbiology. 12, 13, p. 1113-1117 5 p.

Research output: Contribution to journalComment / DebateOtherpeer-review

The Ribosomal Protein uL22 Modulates the Shape of the Protein Exit Tunnel

Wekselman, I., Zimmerman, E., Davidovich, C., Belousoff, M., Matzov, D., Krupkin, M., Rozenberg, H., Bashan, A., Friedlander, G., Kjeldgaard, J., Ingmer, H., Lindahl, L., Zengel, J. M. & Yonath, A., 1 Aug 2017, In : Structure. 25, 8, p. 1233-1241 9 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
File
2016

Effective assembly of fimbriae in Escherichia coli depends on the translocation assembly module nanomachine

Stubenrauch, C., Belousoff, M. J., Hay, I. D., Shen, H-H., Lillington, J., Tuck, K. L., Peters, K. M., Phan, M-D., Lo, A. W., Schembri, M. A., Strugnell, R. A., Waksman, G. & Lithgow, T., 2016, In : Nature Microbiology. 1, p. 1-8 8 p., 16064 .

Research output: Contribution to journalArticleResearchpeer-review

Open Access

Neomycin B-cyclen conjugates and their Zn(II) complexes as RNA-binding agents

Kong, B., Joshi, T., Belousoff, M. J., Tor, Y., Graham, B. & Spiccia, L., 2016, In : Journal of Inorganic Biochemistry. 162, p. 334-342 9 p.

Research output: Contribution to journalArticleResearchpeer-review

Ribosomal antibiotics: Contemporary challenges

Auerbach-Nevo, T., Baram, D., Bashan, A., Belousoff, M., Breiner, E., Davidovich, C., Cimicata, G., Eyal, Z., Halfon, Y., Krupkin, M., Matzov, D., Metz, M., Rufayda, M., Peretz, M., Pick, O., Pyetan, E., Rozenberg, H., Shalev-Benami, M., Wekselman, I., Zarivach, R. & 11 others, Zimmerman, E., Assis, N., Bloch, J., Israeli, H., Kalaora, R., Lim, L., Sade-Falk, O., Shapira, T., Taha-Salaime, L., Tang, H. & Yonath, A., 29 Jun 2016, In : Antibiotics. 5, 3, 11 p., 24.

Research output: Contribution to journalReview ArticleResearchpeer-review

Open Access
File
2015

Conserved features in TamA enable interaction with TamB to drive the activity of the translocation and assembly module

Selkrig, J. P., Belousoff, M. J., Headey, S. J., Heinz, E., Shiota, T., Shen, H-H., Beckham, S. A., Bamert, R. S., Phan, M-D., Schembri, M. A., Wilce, M. C., Scanlon, M. J., Strugnell, R. A. & Lithgow, T. J., 2015, In : Scientific Reports. 5, 12 p., 12905.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
File

Evolution of the translocation and assembly module (TAM)

Heinz, E., Selkrig, J. P., Belousoff, M. J. & Lithgow, T. J., 2015, In : Genome Biology and Evolution. 7, 6, p. 1628 - 1643 16 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
File

Integration of posttranscriptional gene networks into metabolic adaptation and biofilm maturation in candida albicans

Verma-Gaur, J., Qu, Y., Harrison, P. F., Lo, T. L., Quenault, T. L., Dagley, M. J., Belousoff, M. J., Powell, D. R., Beilharz, T. H. & Traven, A., 2015, In : PLoS Genetics. 11, 10, 28 p., e1005590.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
File

The β-Barrel Assembly Machinery Complex

Leyton, D. L., Belousoff, M. J. & Lithgow, T. J., 2015, The BAM complex: Methods and Protocols. Buchanan, S. K. & Noinaj, N. (eds.). 1st ed. New York NY USA: Humana Press, Vol. 1329. 16 p. (Methods in Molecular Biology: Springer Protocols; vol. 1329).

Research output: Chapter in Book/Report/Conference proceedingChapter (Book)Otherpeer-review

2014

A mortise-tenon joint in the transmembrane domain modulates autotransporter assembly into bacterial outer membranes

Leyton, D. L., Johnson, M. D., Thapa, R., Huysmans, G., Dunstan, R. A., Celik, N., Shen, H-H., Loo, D., Belousoff, M. J., Purcell, A. W., Henderson, I. R., Beddoe, T. C., Rossjohn, J., Martin, L. L., Strugnell, R. A. & Lithgow, T. J., 2014, In : Nature Communications. 5, (Art. No.: 4239), p. 1 - 11 11 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access

Reconstitution of a nanomachine driving the assembly of proteins into bacterial outer membranes

Shen, H-H., Leyton, D. L., Shiota, T., Belousoff, M. J., Noinaj, N., Lu, J., Holt, S. A., Tan, K. S., Selkrig, J. P., Webb, C. T., Buchanan, S. K., Martin, L. L. & Lithgow, T. J., 2014, In : Nature Communications. 5, 5078, p. 1 - 10 10 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
2012

Copper(II), zinc(II) and nickel(II) complexes as nuclease mimetics

Desbouis, D., Troitsky, I. P., Belousoff, M. J., Spiccia, L. & Graham, B., 2012, In : Coordination Chemistry Reviews. 256, 11-12, p. 897 - 937 41 p.

Research output: Contribution to journalArticleResearchpeer-review

Discovery of an archetypal protein transport system in bacterial outer membranes

Selkrig, J., Mosbahi, K., Webb, C. T., Belousoff, M. J., Perry, A. J., Wells, T. J., Morris, F. C., Leyton, D. L., Totsika, M., Phan, M-D., Celik, N., Kelly, M., Oates, C., Hartland, E. L., Robins-Browne, R. M., Ramarathinam, S. H., Purcell, A. W., Schembri, M. A., Strugnell, R. A., Henderson, I. R. & 2 others, Walker, D. & Lithgow, T. J., 2012, In : Nature Structural and Molecular Biology. 19, 5 (S 1), p. 506 - 510 5 p.

Research output: Contribution to journalArticleResearchpeer-review

The evolution of new lipoprotein subunits of the bacterial outer membrane BAM complex

Anwari, K., Webb, C. T., Poggio, S., Perry, A. J., Belousoff, M. J., Celik, N., Ramm, G., Lovering, A., Sockett, R. E., Smit, J., Jacobs-Wagner, C. & Lithgow, T. J., 2012, In : Molecular Microbiology. 84, 5, p. 832 - 844 13 p.

Research output: Contribution to journalArticleResearchpeer-review

2011

A vestige of a prebiotic bonding machine is functioning within the contemporary ribosome

Krupkin, M., Matzov, D., Tang, H., Metz, M., Kalaora, R., Belousoff, M. J., Zimmerman, E., Bashan, A. & Yonath, A., 2011, In : Philosophical Transactions of the Royal Society B: Biological Sciences. 366, 1580, p. 2972 - 2978 7 p.

Research output: Contribution to journalArticleResearchpeer-review

Crystal structure of the synergistic antibiotic pair, lankamycin and lankacidin, in complex with the large ribosomal subunit

Belousoff, M., Shapira, T., Bashan, A., Zimmerman, E., Rozenberg, H., Arakawa, K., Kinashi, H. & Yonath, A., 2011, In : Proceedings of the National Academy of Sciences. 108, 7, p. 2717 - 2722 6 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
2010

Ancient machinery embedded in the contemporary ribosome

Belousoff, M., Davidovich, C., Zimmerman, E., Caspi, Y., Wekselman, I., Rozenszajn, L., Shapira, T., Sade-Falk, O., Taha, L., Bashan, A., Weiss, M. & Yonath, A., 2010, In : Biochemical Society Transactions. 38, 2, p. 422 - 427 6 p.

Research output: Contribution to journalArticleResearchpeer-review

Linking the RNA world to modern life: The proto-ribosome conception

Bashan, A., Belousoff, M. J., Davidovich, C. & Yonath, A., 2010, In : Origins of Life and Evolution of Biospheres. 40, 4, p. 425-429 5 p.

Research output: Contribution to journalArticleResearchpeer-review

On the development towards the modern world: A plausible role of uncoded peptides in the rnaworld

Belousoff, M. J., Davidovich, C., Bashan, A. & Yonath, A., 2010, In : Origins of Life and Evolution of Biospheres. 40, 4, p. 415-420 6 p.

Research output: Contribution to journalArticleResearchpeer-review

The proto-ribosome: An ancient nano-machine for peptide bond formation

Davidovich, C., Belousoff, M., Wekselman, I., Shapira, T., Krupkin, M., Zimmerman, E., Bashan, A. & Yonath, A., 18 Jun 2010, In : Israel Journal of Chemistry. 50, 1, p. 29-35 7 p.

Research output: Contribution to journalReview ArticleResearchpeer-review

The structure of ribosome-lankacidin complex reveals ribosomal sites for synergistic antibiotics

Auerbach, T., Mermershtain, I., Davidovich, C., Bashan, A., Belousoff, M., Wekselman, I., Zimmerman, E., Xiong, L., Klepacki, D., Arakawa, K., Kinashi, H., Mankin, A. & Yonath, A., 2010, In : Proceedings of the National Academy of Sciences. 107, 5, p. 1983 - 1988 6 p.

Research output: Contribution to journalArticleResearchpeer-review

2009

Binding of HIV-1 TAR mRNA to a peptide nucleic acid oligomer and its conjugates with metal-ion-binding multidentate ligands

Belousoff, M. J., Gasser, G. A., Graham, B., Tor, Y. & Spiccia, L., 2009, In : Journal of Biological Inorganic Chemistry. 14, p. 287 - 300 14 p.

Research output: Contribution to journalArticleResearchpeer-review

Cleavage of RNA oligonucleotides by aminoglycosides

Belousoff, M. J., Graham, B., Spiccia, L. & Tor, Y., 2009, In : Organic and Biomolecular Chemistry. 7, p. 30 - 33 4 p.

Research output: Contribution to journalArticleResearchpeer-review

Erratum: Ruthenium(II) complexes incorporating 2-(2′-Pyridyl) pyrimidine-4-carboxylic acid (Inorganic Chemistry (2009) 48: 8 (3896) 10.1021/ic9004505)

Nickita, N., Gasser, G., Pearson, P., Belousoff, M. J., Goh, L. Y., Bond, A. M., Deacon, G. B. & Spiccia, L., 20 Apr 2009, In : Inorganic Chemistry. 48, 8, p. 3896 1 p.

Research output: Contribution to journalComment / DebateOtherpeer-review

New macrocyclic terbium(III) complex for use in RNA footprinting experiments

Belousoff, M. J., Ung, P., Forsyth, C. M., Tor, Y., Spiccia, L. & Graham, B., 2009, In : Journal of the American Chemical Society. 131, p. 1106 - 1114 9 p.

Research output: Contribution to journalArticleResearchpeer-review

Ruthenium(ll) complexes incorporating 2-(2'-Pyridyl)pyrimidine-4- carboxylic acid

Nickita, N., Gasser, G. A., Pearson, P., Belousoff, M. J., Goh, L. Y., Bond, A. M., Deacon, G. B. & Spiccia, L., 2009, In : Inorganic Chemistry. 48, 1, p. 68 - 81 14 p.

Research output: Contribution to journalArticleResearchpeer-review

Synthesis, X-ray structure of ferrocene bearing Bis(Zn-cyclen) complexes and the selective electrochemical sensing of TpT

Zeng, Z., Torriero, A. A. J., Belousoff, M. J., Bond, A. M. & Spiccia, L., 2009, In : Chemistry - A European Journal. 15, p. 10988 - 10996 9 p.

Research output: Contribution to journalArticleResearchpeer-review

The evolving ribosome: from non-coded peptide bond formation to sophisticated translation machinery

Davidovich, C., Belousoff, M., Bashan, A. & Yonath, A., 2009, In : Research in Microbiology. 160, 7, p. 487 - 492 6 p.

Research output: Contribution to journalArticleResearchpeer-review

Synthesis, copper(II) complexation, 64Cu-labeling, and bioconjugation of a new bis(2-pyridylmethyl) derivative of 1,4,7- triazacyclononane

Gasser, G. A., Tjioe, L., Graham, B., Belousoff, M. J., Juran, S., Walther, M., Kunstler, J-U., Bergmann, R., Stephan, H. & Spiccia, L., 2008, In : Bioconjugate Chemistry. 19, p. 719 - 730 12 p.

Research output: Contribution to journalArticleResearchpeer-review

Synthesis, X-Ray Crystal Structures, and Phosphate Ester Cleavage Properties of bis(2-Pyridylmethyl)amine Copper(II) Complexes with Guanidinium Pendant Groups

Belousoff, M. J., Tjioe, L., Graham, B. & Spiccia, L., 2008, In : Inorganic Chemistry. 47, 19, p. 8641 - 8651 11 p.

Research output: Contribution to journalArticleResearchpeer-review

2007

Recognition of thymine and related nucleosides by a ZnII-cyclen complex bearing a ferrocenyl pendant

Gasser, G. A., Belousoff, M. J., Bond, A. M., Kosowski, Z. E. & Spiccia, L., 2007, In : Inorganic Chemistry. 46, 5, p. 1665 - 1674 10 p.

Research output: Contribution to journalArticleResearchpeer-review

Syntheses, structures and hydrolytic properties of copper(II) complexes of asymmetrically N-functionalised 1,4,7-triazacyclononane ligands

Belousoff, M. J., Battle, A. R., Graham, B. & Spiccia, L., 2007, In : Polyhedron. 26, 2, p. 344 - 355 12 p.

Research output: Contribution to journalArticleResearchpeer-review

Synthesis, structure, spectroscopic properties, and electrochemical oxidation of Ruthenium(II) complexes incorporating Monocarboxylate Bipyridine ligands

Nickita, N., Belousoff, M. J., Bhatt, A. I., Bond, A. M., Deacon, G. B., Gasser, G. A. & Spiccia, L., 2007, In : Inorganic Chemistry. 46, 21, p. 8638 - 8651 14 p.

Research output: Contribution to journalArticleResearchpeer-review

2006

Facile synthesis and detailed characterization of a new ferrocenyl uracil peptide nucleic acid monomer

Gasser, G. A., Belousoff, M. J., Bond, A. M. & Spiccia, L., 2006, In : Journal of Organic Chemistry. 71, 20, p. 7565 - 7573 9 p.

Research output: Contribution to journalArticleResearchpeer-review

Oxalato-bridged dinuclear copper(II) complexes of N-alkylated derivatives of 1,4,7-triazacyclononane: synthesis, X-ray crystal structures and magnetic properties

Belousoff, M. J., Graham, B., Moubaraki, B., Murray, K. S. & Spiccia, L., 2006, In : European Journal of Inorganic Chemistry. 23, p. 4872 - 4878 7 p.

Research output: Contribution to journalArticleResearchpeer-review

Synthesis, X-ray crystal structures, magnetism, and phosphate ester cleavage properties of copper(II) complexes of N-substituted derivatives of 1,4,7-triazacyclononane

Belousoff, M. J., Duriska, M., Graham, B., Batten, S. R., Moubaraki, B., Murray, K. S. & Spiccia, L., 2006, In : Inorganic Chemistry. 45, 9, p. 3746 - 3755 10 p.

Research output: Contribution to journalArticleResearchpeer-review

2005

4',4",5',5"-Tetranitro-2,3:11,12-dibenzo- 1,4,7,10,13,16-hexaoxacyclooctadeca-2,11-diene acetonitrile solvate monohydrate

Belousoff, M. J., Langford, S. J., Latter, M. J. & Lau, V-L., 2005, In : Acta Crystallographica Section E: Structure Reports Online. 61, p. o3283 - o3284 2 p.

Research output: Contribution to journalArticleResearchpeer-review

Kinetics and mechanism of hydrolysis of a model phosphate diester by [Cu(Me3tacn)(OH2)2]2+ (Me 3tacn = 1,4,7-trimethyl-1,4,7-triazacyclononane)

Fry, F., Fischmann, A. J., Belousoff, M. J., Spiccia, L. & Brugger, J., 2005, In : Inorganic Chemistry. 44, p. 941 - 950 10 p.

Research output: Contribution to journalArticleResearchpeer-review